DK3619199T3 - Fremstilling af 2-([1,2,3]triazol-2-yl)-benzoesyrederivater - Google Patents
Fremstilling af 2-([1,2,3]triazol-2-yl)-benzoesyrederivater Download PDFInfo
- Publication number
- DK3619199T3 DK3619199T3 DK18722948.9T DK18722948T DK3619199T3 DK 3619199 T3 DK3619199 T3 DK 3619199T3 DK 18722948 T DK18722948 T DK 18722948T DK 3619199 T3 DK3619199 T3 DK 3619199T3
- Authority
- DK
- Denmark
- Prior art keywords
- triazol
- preparation
- benzoic acid
- acid derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
- B01J23/72—Copper
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2017060451 | 2017-05-03 | ||
| PCT/EP2018/061172 WO2018202689A1 (en) | 2017-05-03 | 2018-05-02 | Preparation of 2-([1,2,3]triazol-2-yl)-benzoic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3619199T3 true DK3619199T3 (da) | 2021-09-27 |
Family
ID=62116854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18722948.9T DK3619199T3 (da) | 2017-05-03 | 2018-05-02 | Fremstilling af 2-([1,2,3]triazol-2-yl)-benzoesyrederivater |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11124488B2 (da) |
| EP (1) | EP3619199B1 (da) |
| JP (1) | JP7182562B2 (da) |
| KR (1) | KR102582197B1 (da) |
| CN (1) | CN110612291B (da) |
| CA (1) | CA3059394C (da) |
| CY (1) | CY1124777T1 (da) |
| DK (1) | DK3619199T3 (da) |
| ES (1) | ES2892161T3 (da) |
| HR (1) | HRP20211304T1 (da) |
| HU (1) | HUE055904T2 (da) |
| IL (1) | IL270274B (da) |
| LT (1) | LT3619199T (da) |
| MX (1) | MX2019012902A (da) |
| PL (1) | PL3619199T3 (da) |
| PT (1) | PT3619199T (da) |
| RS (1) | RS62357B1 (da) |
| SI (1) | SI3619199T1 (da) |
| TW (1) | TWI756418B (da) |
| WO (1) | WO2018202689A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3175369A1 (en) | 2020-04-19 | 2021-10-28 | Guy Braunstein | Medical use of daridorexant |
| TW202400149A (zh) | 2022-05-13 | 2024-01-01 | 瑞士商愛杜西亞製藥有限公司 | 經噻唑并芳基-甲基取代之環狀肼-n-甲醯胺衍生物 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007285371A1 (en) | 2006-08-15 | 2008-02-21 | Actelion Pharmaceuticals Ltd. | Azetidine compounds as orexin receptor antagonists |
| DE602007009284D1 (de) | 2006-09-29 | 2010-10-28 | Actelion Pharmaceuticals Ltd | 3-aza-bicycloä3.1.0ühexanderivate |
| PE20081229A1 (es) | 2006-12-01 | 2008-08-28 | Merck & Co Inc | Antagonistas de receptor de orexina de diazepam sustituido |
| AR064561A1 (es) | 2006-12-28 | 2009-04-08 | Actelion Pharmaceuticals Ltd | Derivados de 2-aza-biciclo[3.1.0]hexano y su uso en la preparacion de un medicamento para el tratamiento de enfermedades relacionadas con disfunciones generales del sistema de la orexina. |
| JP2010526869A (ja) | 2007-05-14 | 2010-08-05 | アクテリオン ファーマシューティカルズ リミテッド | ２−シクロプロピル−チアゾール誘導体 |
| EP2150115B1 (en) | 2007-05-23 | 2013-09-18 | Merck Sharp & Dohme Corp. | Cyclopropyl pyrrolidine orexin receptor antagonists |
| JP5847087B2 (ja) | 2009-10-23 | 2016-01-20 | ヤンセン ファーマシューティカ エヌ．ベー． | オレキシン受容体調節因子としての縮合複素環式化合物 |
| KR101859400B1 (ko) | 2009-10-23 | 2018-05-18 | 얀센 파마슈티카 엔.브이. | 오렉신 수용체 조절제로서의 이치환된 옥타하이드로피롤로［3,4-ｃ］피롤 |
| US9062044B2 (en) | 2009-10-23 | 2015-06-23 | Janssen Pharmaceutica Nv | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
| US20130281465A1 (en) | 2010-12-17 | 2013-10-24 | Taisho Pharmaceutical Co., Ltd. | Pyrazole derivative |
| WO2012085857A1 (en) | 2010-12-22 | 2012-06-28 | Actelion Pharmaceuticals Ltd | 3,8-diaza-bicyclo[4.2.0]oct-3-yl amides |
| EP2680697B1 (en) | 2011-03-03 | 2018-01-10 | Merck Sharp & Dohme Corp. | Process for the preparation of an orexin receptor antagonist |
| US9586962B2 (en) | 2011-04-20 | 2017-03-07 | Janssen Pharmaceutica Nv | Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators |
| TW201315730A (zh) | 2011-07-05 | 2013-04-16 | 大正製藥股份有限公司 | 甲基哌啶衍生物 |
| WO2013050938A1 (en) * | 2011-10-04 | 2013-04-11 | Actelion Pharmaceuticals Ltd | 3,7-diazabicyclo[3.3.1]nonane and 9-oxa-3,7-diazabicyclo[3.3.1]nonane derivatives |
| IN2014CN04127A (da) | 2011-11-08 | 2015-07-10 | Actelion Pharmaceuticals Ltd | |
| US9441254B2 (en) | 2012-05-09 | 2016-09-13 | Merck Sharp & Dohme Corp. | Process for the preparation of an intermediate for an orexin receptor antagonist |
| KR101689093B1 (ko) | 2012-06-04 | 2016-12-22 | 액테리온 파마슈티칼 리미티드 | 벤즈이미다졸-프롤린 유도체 |
| JP2014015452A (ja) | 2012-06-15 | 2014-01-30 | Taisho Pharmaceutical Co Ltd | ピラゾール誘導体を含有する医薬 |
| SG11201502493XA (en) * | 2012-10-10 | 2015-04-29 | Actelion Pharmaceuticals Ltd | Orexin receptor antagonists which are [ortho bi (hetero )aryl]-[2-(meta bi (hetero )aryl)-pyrrolidin-1-yl]-methanone derivatives |
| JP2016510810A (ja) | 2013-03-12 | 2016-04-11 | アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | オレキシン受容体アンタゴニストとしてのアゼチジンアミド誘導体 |
| TW201444821A (zh) | 2013-03-13 | 2014-12-01 | Janssen Pharmaceutica Nv | 經取代之哌啶化合物及其作為食慾素受體調節劑之用途 |
| TW201444849A (zh) * | 2013-03-13 | 2014-12-01 | Janssen Pharmaceutica Nv | 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途 |
| UA119151C2 (uk) | 2013-12-03 | 2019-05-10 | Ідорсія Фармасьютікалз Лтд | КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА |
| HUE035731T2 (hu) | 2013-12-03 | 2018-05-28 | Idorsia Pharmaceuticals Ltd | (S)-(2-(6-klór-7-metil-1H-benzo[d]imidazol-2-il)-2-metilpirrolidin-1-il)(5-metoxi-2- (2H-l,2,3-triazol-2-il)fenil)metanon kristályos formája és alkalmazása orexin receptor antagonistaként |
| TR201815342T4 (tr) | 2013-12-04 | 2018-11-21 | Idorsia Pharmaceuticals Ltd | Benzimidazol-prolin türevlerinin kullanımı. |
| TW201613891A (en) | 2014-02-12 | 2016-04-16 | Eolas Therapeutics Inc | Substituted prolines / piperidines as orexin receptor antagonists |
| WO2016020403A1 (en) | 2014-08-04 | 2016-02-11 | Sandoz Ag | Preparation of a benzoic acid derivative and its use for the preparation of suvorexant |
| CN104649983B (zh) * | 2014-12-23 | 2018-01-23 | 广东东阳光药业有限公司 | 一种酸的制备方法 |
| US10131653B2 (en) | 2015-04-24 | 2018-11-20 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
-
2018
- 2018-05-02 US US16/610,413 patent/US11124488B2/en active Active
- 2018-05-02 ES ES18722948T patent/ES2892161T3/es active Active
- 2018-05-02 MX MX2019012902A patent/MX2019012902A/es unknown
- 2018-05-02 LT LTEPPCT/EP2018/061172T patent/LT3619199T/lt unknown
- 2018-05-02 PT PT18722948T patent/PT3619199T/pt unknown
- 2018-05-02 IL IL270274A patent/IL270274B/en unknown
- 2018-05-02 SI SI201830396T patent/SI3619199T1/sl unknown
- 2018-05-02 CN CN201880028762.9A patent/CN110612291B/zh active Active
- 2018-05-02 WO PCT/EP2018/061172 patent/WO2018202689A1/en unknown
- 2018-05-02 TW TW107114814A patent/TWI756418B/zh active
- 2018-05-02 CA CA3059394A patent/CA3059394C/en active Active
- 2018-05-02 JP JP2019559016A patent/JP7182562B2/ja active Active
- 2018-05-02 KR KR1020197035319A patent/KR102582197B1/ko active IP Right Grant
- 2018-05-02 EP EP18722948.9A patent/EP3619199B1/en active Active
- 2018-05-02 HU HUE18722948A patent/HUE055904T2/hu unknown
- 2018-05-02 PL PL18722948T patent/PL3619199T3/pl unknown
- 2018-05-02 DK DK18722948.9T patent/DK3619199T3/da active
- 2018-05-02 RS RS20211164A patent/RS62357B1/sr unknown
-
2021
- 2021-08-12 HR HRP20211304TT patent/HRP20211304T1/hr unknown
- 2021-10-06 CY CY20211100871T patent/CY1124777T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL270274B (en) | 2022-08-01 |
| CN110612291A (zh) | 2019-12-24 |
| ES2892161T3 (es) | 2022-02-02 |
| JP2020518573A (ja) | 2020-06-25 |
| MX2019012902A (es) | 2019-12-16 |
| IL270274A (da) | 2019-12-31 |
| CY1124777T1 (el) | 2022-11-25 |
| SI3619199T1 (sl) | 2021-11-30 |
| CN110612291B (zh) | 2024-02-13 |
| PL3619199T3 (pl) | 2021-12-20 |
| KR102582197B1 (ko) | 2023-09-22 |
| HUE055904T2 (hu) | 2021-12-28 |
| EP3619199A1 (en) | 2020-03-11 |
| TW201843144A (zh) | 2018-12-16 |
| TWI756418B (zh) | 2022-03-01 |
| EP3619199B1 (en) | 2021-07-07 |
| US20210114997A1 (en) | 2021-04-22 |
| KR20200003097A (ko) | 2020-01-08 |
| PT3619199T (pt) | 2021-10-01 |
| RS62357B1 (sr) | 2021-10-29 |
| JP7182562B2 (ja) | 2022-12-02 |
| CA3059394C (en) | 2023-09-12 |
| CA3059394A1 (en) | 2018-11-08 |
| US11124488B2 (en) | 2021-09-21 |
| WO2018202689A1 (en) | 2018-11-08 |
| HRP20211304T1 (hr) | 2021-11-12 |
| LT3619199T (lt) | 2021-09-27 |
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