SI3619199T1 - Priprava derivatov 2-((1,2,3)triazol-2-il)-benzojske kisline - Google Patents
Priprava derivatov 2-((1,2,3)triazol-2-il)-benzojske kislineInfo
- Publication number
- SI3619199T1 SI3619199T1 SI201830396T SI201830396T SI3619199T1 SI 3619199 T1 SI3619199 T1 SI 3619199T1 SI 201830396 T SI201830396 T SI 201830396T SI 201830396 T SI201830396 T SI 201830396T SI 3619199 T1 SI3619199 T1 SI 3619199T1
- Authority
- SI
- Slovenia
- Prior art keywords
- triazol
- preparation
- benzoic acid
- acid derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
- B01J23/72—Copper
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2017060451 | 2017-05-03 | ||
| EP18722948.9A EP3619199B1 (en) | 2017-05-03 | 2018-05-02 | Preparation of 2-([1,2,3]triazol-2-yl)-benzoic acid derivatives |
| PCT/EP2018/061172 WO2018202689A1 (en) | 2017-05-03 | 2018-05-02 | Preparation of 2-([1,2,3]triazol-2-yl)-benzoic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3619199T1 true SI3619199T1 (sl) | 2021-11-30 |
Family
ID=62116854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201830396T SI3619199T1 (sl) | 2017-05-03 | 2018-05-02 | Priprava derivatov 2-((1,2,3)triazol-2-il)-benzojske kisline |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11124488B2 (sl) |
| EP (1) | EP3619199B1 (sl) |
| JP (1) | JP7182562B2 (sl) |
| KR (1) | KR102582197B1 (sl) |
| CN (1) | CN110612291B (sl) |
| CA (1) | CA3059394C (sl) |
| CY (1) | CY1124777T1 (sl) |
| DK (1) | DK3619199T3 (sl) |
| ES (1) | ES2892161T3 (sl) |
| HR (1) | HRP20211304T1 (sl) |
| HU (1) | HUE055904T2 (sl) |
| IL (1) | IL270274B (sl) |
| LT (1) | LT3619199T (sl) |
| MX (1) | MX2019012902A (sl) |
| PL (1) | PL3619199T3 (sl) |
| PT (1) | PT3619199T (sl) |
| RS (1) | RS62357B1 (sl) |
| SI (1) | SI3619199T1 (sl) |
| TW (1) | TWI756418B (sl) |
| WO (1) | WO2018202689A1 (sl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4138822A1 (en) | 2020-04-19 | 2023-03-01 | Idorsia Pharmaceuticals Ltd | Medical use of daridorexant |
| TW202400149A (zh) | 2022-05-13 | 2024-01-01 | 瑞士商愛杜西亞製藥有限公司 | 經噻唑并芳基-甲基取代之環狀肼-n-甲醯胺衍生物 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7994336B2 (en) | 2006-08-15 | 2011-08-09 | Actelion Pharmaceuticals Ltd. | Azetidine compounds as orexin receptor antagonists |
| WO2008038251A2 (en) | 2006-09-29 | 2008-04-03 | Actelion Pharmaceuticals Ltd | 3-aza-bicyclo[3.1.0]hexane derivatives |
| PE20081229A1 (es) * | 2006-12-01 | 2008-08-28 | Merck & Co Inc | Antagonistas de receptor de orexina de diazepam sustituido |
| TW200833328A (en) | 2006-12-28 | 2008-08-16 | Actelion Pharmaceuticals Ltd | 2-aza-bicyclo[3.1.0]hexane derivatives |
| JP2010526869A (ja) | 2007-05-14 | 2010-08-05 | アクテリオン ファーマシューティカルズ リミテッド | ２−シクロプロピル−チアゾール誘導体 |
| WO2008150364A1 (en) | 2007-05-23 | 2008-12-11 | Merck & Co., Inc. | Cyclopropyl pyrrolidine orexin receptor antagonists |
| JP5759470B2 (ja) | 2009-10-23 | 2015-08-05 | ヤンセン ファーマシューティカ エヌ．ベー． | オレキシン受容体調節因子としての二置換オクタヒドロピロロ［３，４−ｃ］ピロール |
| JP5848251B2 (ja) | 2009-10-23 | 2016-01-27 | ヤンセン ファーマシューティカ エヌ．ベー． | オレキシン受容体調節因子としての縮合複素環式化合物 |
| US8680275B2 (en) | 2009-10-23 | 2014-03-25 | Janssen Pharmaceutica Nv | Fused heterocyclic compounds as orexin receptor modulators |
| NZ611865A (en) | 2010-12-17 | 2014-11-28 | Taisho Pharmaceutical Co Ltd | Pyrazole derivative |
| WO2012085857A1 (en) | 2010-12-22 | 2012-06-28 | Actelion Pharmaceuticals Ltd | 3,8-diaza-bicyclo[4.2.0]oct-3-yl amides |
| US9108959B2 (en) | 2011-03-03 | 2015-08-18 | Merck Sharp & Dohme Corp. | Process for the preparation of an orexin receptor antagonist |
| US9586962B2 (en) | 2011-04-20 | 2017-03-07 | Janssen Pharmaceutica Nv | Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators |
| WO2013005755A1 (ja) | 2011-07-05 | 2013-01-10 | 大正製薬株式会社 | メチルピペリジン誘導体 |
| WO2013050938A1 (en) * | 2011-10-04 | 2013-04-11 | Actelion Pharmaceuticals Ltd | 3,7-diazabicyclo[3.3.1]nonane and 9-oxa-3,7-diazabicyclo[3.3.1]nonane derivatives |
| TWI565703B (zh) | 2011-11-08 | 2017-01-11 | 艾克泰聯製藥有限公司 | ２-（１，２，３-三唑-２-基）苯甲醯胺及３-（１，２，３-三唑-２-基）吡啶醯胺衍生物 |
| WO2013169610A1 (en) | 2012-05-09 | 2013-11-14 | Merck Sharp & Dohme Corp. | Process for the preparation of an intermediate for an orexin receptor antagonist |
| EP2855453B1 (en) | 2012-06-04 | 2016-12-07 | Actelion Pharmaceuticals Ltd. | Benzimidazole-proline derivatives |
| JP2014015452A (ja) | 2012-06-15 | 2014-01-30 | Taisho Pharmaceutical Co Ltd | ピラゾール誘導体を含有する医薬 |
| CN104703980B (zh) * | 2012-10-10 | 2017-09-22 | 埃科特莱茵药品有限公司 | 属于[邻双(杂)芳基]‑[2‑(间双(杂)芳基)吡咯烷‑1‑基]甲酮衍生物的食欲素受体拮抗剂 |
| KR20150130413A (ko) | 2013-03-12 | 2015-11-23 | 액테리온 파마슈티칼 리미티드 | 오렉신 수용체 길항제로서의 아제티딘 아미드 유도체 |
| TW201444849A (zh) * | 2013-03-13 | 2014-12-01 | Janssen Pharmaceutica Nv | 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途 |
| TW201444821A (zh) | 2013-03-13 | 2014-12-01 | Janssen Pharmaceutica Nv | 經取代之哌啶化合物及其作為食慾素受體調節劑之用途 |
| UA119151C2 (uk) | 2013-12-03 | 2019-05-10 | Ідорсія Фармасьютікалз Лтд | КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА |
| PT3077389T (pt) * | 2013-12-03 | 2017-12-15 | Idorsia Pharmaceuticals Ltd | Forma cristalina de (s)-(2-(6-cloro-7-metil-1hbenzo[d]imidazol-2-il)-2-metilpirrolidin-1-il)(5-metoxi-2-(2h-1,2,3-triazol-2-il)fenil)metanona e a sua utilização como como antagonistas do receptor de orexina |
| LT3077391T (lt) | 2013-12-04 | 2018-10-25 | Idorsia Pharmaceuticals Ltd | Benzimidazolo prolino darinių panaudojimas |
| UY35993A (es) * | 2014-02-12 | 2015-08-31 | Eolas Therapeutics Inc | Prolinas / piperidinas sustituidas como antagonistas del receptor de orexina |
| WO2016020403A1 (en) | 2014-08-04 | 2016-02-11 | Sandoz Ag | Preparation of a benzoic acid derivative and its use for the preparation of suvorexant |
| CN104649983B (zh) * | 2014-12-23 | 2018-01-23 | 广东东阳光药业有限公司 | 一种酸的制备方法 |
| US10131653B2 (en) * | 2015-04-24 | 2018-11-20 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
-
2018
- 2018-05-02 CN CN201880028762.9A patent/CN110612291B/zh active Active
- 2018-05-02 RS RS20211164A patent/RS62357B1/sr unknown
- 2018-05-02 CA CA3059394A patent/CA3059394C/en active Active
- 2018-05-02 IL IL270274A patent/IL270274B/en unknown
- 2018-05-02 HU HUE18722948A patent/HUE055904T2/hu unknown
- 2018-05-02 ES ES18722948T patent/ES2892161T3/es active Active
- 2018-05-02 JP JP2019559016A patent/JP7182562B2/ja active Active
- 2018-05-02 WO PCT/EP2018/061172 patent/WO2018202689A1/en unknown
- 2018-05-02 TW TW107114814A patent/TWI756418B/zh active
- 2018-05-02 US US16/610,413 patent/US11124488B2/en active Active
- 2018-05-02 KR KR1020197035319A patent/KR102582197B1/ko active IP Right Grant
- 2018-05-02 LT LTEPPCT/EP2018/061172T patent/LT3619199T/lt unknown
- 2018-05-02 PT PT18722948T patent/PT3619199T/pt unknown
- 2018-05-02 PL PL18722948T patent/PL3619199T3/pl unknown
- 2018-05-02 EP EP18722948.9A patent/EP3619199B1/en active Active
- 2018-05-02 DK DK18722948.9T patent/DK3619199T3/da active
- 2018-05-02 MX MX2019012902A patent/MX2019012902A/es unknown
- 2018-05-02 SI SI201830396T patent/SI3619199T1/sl unknown
-
2021
- 2021-08-12 HR HRP20211304TT patent/HRP20211304T1/hr unknown
- 2021-10-06 CY CY20211100871T patent/CY1124777T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT3619199T (pt) | 2021-10-01 |
| HUE055904T2 (hu) | 2021-12-28 |
| RS62357B1 (sr) | 2021-10-29 |
| PL3619199T3 (pl) | 2021-12-20 |
| CA3059394C (en) | 2023-09-12 |
| WO2018202689A1 (en) | 2018-11-08 |
| IL270274B (en) | 2022-08-01 |
| JP2020518573A (ja) | 2020-06-25 |
| CA3059394A1 (en) | 2018-11-08 |
| US20210114997A1 (en) | 2021-04-22 |
| JP7182562B2 (ja) | 2022-12-02 |
| HRP20211304T1 (hr) | 2021-11-12 |
| EP3619199B1 (en) | 2021-07-07 |
| ES2892161T3 (es) | 2022-02-02 |
| TW201843144A (zh) | 2018-12-16 |
| CN110612291A (zh) | 2019-12-24 |
| CN110612291B (zh) | 2024-02-13 |
| DK3619199T3 (da) | 2021-09-27 |
| TWI756418B (zh) | 2022-03-01 |
| IL270274A (sl) | 2019-12-31 |
| MX2019012902A (es) | 2019-12-16 |
| LT3619199T (lt) | 2021-09-27 |
| KR102582197B1 (ko) | 2023-09-22 |
| CY1124777T1 (el) | 2022-11-25 |
| KR20200003097A (ko) | 2020-01-08 |
| US11124488B2 (en) | 2021-09-21 |
| EP3619199A1 (en) | 2020-03-11 |
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