DK3277287T3 - Blandinger af humane mælke-oligosaccharider, der omfatter 3 '-o-sialyllactose - Google Patents
Blandinger af humane mælke-oligosaccharider, der omfatter 3 '-o-sialyllactose Download PDFInfo
- Publication number
- DK3277287T3 DK3277287T3 DK16771503.6T DK16771503T DK3277287T3 DK 3277287 T3 DK3277287 T3 DK 3277287T3 DK 16771503 T DK16771503 T DK 16771503T DK 3277287 T3 DK3277287 T3 DK 3277287T3
- Authority
- DK
- Denmark
- Prior art keywords
- sialyllactose
- mixtures
- human milk
- milk oligosaccharides
- oligosaccharides
- Prior art date
Links
- 210000004251 human milk Anatomy 0.000 title 1
- 235000020256 human milk Nutrition 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229920001542 oligosaccharide Polymers 0.000 title 1
- 150000002482 oligosaccharides Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01018—Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15162014 | 2015-03-31 | ||
| EP15162024 | 2015-03-31 | ||
| PCT/IB2016/051823 WO2016157108A1 (en) | 2015-03-31 | 2016-03-31 | Mixtures of human milk oligosaccharides comprising 3 '-o-sialyllactose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3277287T3 true DK3277287T3 (da) | 2024-01-08 |
Family
ID=57003976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16771503.6T DK3277287T3 (da) | 2015-03-31 | 2016-03-31 | Blandinger af humane mælke-oligosaccharider, der omfatter 3 '-o-sialyllactose |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10588917B2 (da) |
| EP (1) | EP3277287B8 (da) |
| CN (2) | CN107530366A (da) |
| DK (1) | DK3277287T3 (da) |
| ES (1) | ES2971093T3 (da) |
| PL (1) | PL3277287T3 (da) |
| WO (1) | WO2016157108A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107530366A (zh) * | 2015-03-31 | 2018-01-02 | 格礼卡姆股份公司 | 包含3’‑o‑唾液乳糖的人乳寡糖的混合物 |
| WO2019003133A1 (en) | 2017-06-30 | 2019-01-03 | Glycom A/S | PURIFICATION OF OLIGOSACCHARIDES |
| JPWO2021079921A1 (da) * | 2019-10-25 | 2021-04-29 | ||
| CN117858693A (zh) * | 2021-08-24 | 2024-04-09 | 帝斯曼知识产权资产管理有限公司 | 至少一种人乳低聚糖的新颖用途 |
| CN113899827A (zh) * | 2021-09-29 | 2022-01-07 | 中国科学院合肥物质科学研究院 | 一种3’-唾液酸乳糖的检测方法及其应用 |
| WO2023066907A1 (en) | 2021-10-18 | 2023-04-27 | Dsm Ip Assets B.V. | A method for providing an amorphous hmo product by drying |
| WO2024042235A1 (en) * | 2022-08-25 | 2024-02-29 | Dsm Ip Assets B.V. | Hybrid method for producing complex hmos |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0686684A (ja) | 1992-05-26 | 1994-03-29 | Monsanto Co | シアロ抱合体の合成 |
| AU4220397A (en) * | 1996-09-17 | 1998-04-14 | Kyowa Hakko Kogyo Co. Ltd. | Processes for producing sugar nucleotides and complex carbohydrates |
| FR2796082B1 (fr) | 1999-07-07 | 2003-06-27 | Centre Nat Rech Scient | Procede de production d'oligosaccharides |
| DE19958985A1 (de) * | 1999-12-07 | 2001-06-13 | Nutricia Nv | Oligosaccharidmischung |
| CN101415834B (zh) | 2006-03-09 | 2014-09-24 | 国家科学研究中心 | 生产涎化低聚糖的方法 |
| EP2060257A1 (en) * | 2007-11-08 | 2009-05-20 | Nestec S.A. | Prevention and treatment of secondary infections following viral infection |
| CN102341948B (zh) | 2009-03-05 | 2014-04-16 | 日产自动车株式会社 | 双极型二次电池及其生产方法 |
| AU2010233770A1 (en) | 2009-04-07 | 2011-10-27 | Glycom A/S | Novel method for the synthesis of a trisaccharide |
| CN105330705A (zh) | 2010-02-19 | 2016-02-17 | 格礼卡姆股份公司 | 用于制备含n-乙酰乳糖胺的四糖乳糖-n-新四糖(lnnt)的方法 |
| WO2012007585A1 (en) * | 2010-07-16 | 2012-01-19 | Glycom A/S | Derivatization of oligosaccharides |
| EP2454948A1 (en) | 2010-11-23 | 2012-05-23 | Nestec S.A. | Oligosaccharide mixture and food product comprising this mixture, especially infant formula |
| WO2012092153A1 (en) * | 2010-12-31 | 2012-07-05 | Abbott Laboratories | Nutritional compositions comprising human milk oligosaccharides and nucleotides and uses thereof for treating and/or preventing enteric viral infection |
| CA2835986A1 (en) | 2011-05-13 | 2012-11-22 | Glycom A/S | Method for generating human milk oligosaccharides (hmos) or precursors thereof |
| EP2712362A4 (en) | 2011-05-13 | 2014-12-24 | Glycom As | MANUFACTURE OF LACTO-N-TETRAOSE |
| CA2835989A1 (en) | 2011-05-13 | 2012-11-22 | Glycom A/S | Diversification of human milk oligosaccharides (hmos) or precursors thereof |
| EP2522232A1 (en) * | 2011-05-13 | 2012-11-14 | Nestec S.A. | Nutritional products comprising human milk oligosaccharides and methods for manufacture thereof |
| US20140235850A1 (en) | 2011-09-30 | 2014-08-21 | Glycom A/S | Synthesis of hmo core structures |
| WO2013091660A1 (en) | 2011-12-23 | 2013-06-27 | Glycom A/S | A method for obtaining crystalline lacto-n-tetraose and lacto-n-neotetraose precursors and mixtures thereof |
| US20150065702A1 (en) | 2012-03-20 | 2015-03-05 | Glycom A/S | Synthesis of the Trisaccharide 3-O-Fucosyllactose and Intermediates Thereof |
| US20150064220A1 (en) | 2012-03-27 | 2015-03-05 | Abbott Laboratories | Methods for modulating cell-mediated immunity using human milk oligosaccharides |
| WO2014187464A1 (en) * | 2013-05-22 | 2014-11-27 | Glycom As | Synthetic mixture of oligosaccharides for t treating a microbiota of a mammal |
| EP3572521A1 (en) | 2013-09-10 | 2019-11-27 | Jennewein Biotechnologie GmbH | Production of oligosaccharides |
| US9492473B2 (en) * | 2015-01-26 | 2016-11-15 | Kaleido Biosciences, Inc. | Glycan therapeutics and related methods thereof |
| CN107530366A (zh) * | 2015-03-31 | 2018-01-02 | 格礼卡姆股份公司 | 包含3’‑o‑唾液乳糖的人乳寡糖的混合物 |
-
2016
- 2016-03-31 CN CN201680019455.5A patent/CN107530366A/zh active Pending
- 2016-03-31 WO PCT/IB2016/051823 patent/WO2016157108A1/en active Application Filing
- 2016-03-31 ES ES16771503T patent/ES2971093T3/es active Active
- 2016-03-31 EP EP16771503.6A patent/EP3277287B8/en active Active
- 2016-03-31 CN CN202211120765.XA patent/CN115300517A/zh active Pending
- 2016-03-31 PL PL16771503.6T patent/PL3277287T3/pl unknown
- 2016-03-31 US US15/561,684 patent/US10588917B2/en active Active
- 2016-03-31 DK DK16771503.6T patent/DK3277287T3/da active
-
2020
- 2020-03-16 US US16/820,126 patent/US11173171B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3277287A1 (en) | 2018-02-07 |
| PL3277287T3 (pl) | 2024-04-22 |
| CN115300517A (zh) | 2022-11-08 |
| US10588917B2 (en) | 2020-03-17 |
| US11173171B2 (en) | 2021-11-16 |
| US20200281954A1 (en) | 2020-09-10 |
| EP3277287B1 (en) | 2023-11-22 |
| EP3277287B8 (en) | 2023-12-27 |
| EP3277287A4 (en) | 2018-12-26 |
| ES2971093T3 (es) | 2024-06-03 |
| CN107530366A (zh) | 2018-01-02 |
| WO2016157108A1 (en) | 2016-10-06 |
| US20180078574A1 (en) | 2018-03-22 |
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