PL3277287T3 - Mieszaniny oligosacharydów mleka ludzkiego zawierające 3'-O-sialilolaktozę - Google Patents

Mieszaniny oligosacharydów mleka ludzkiego zawierające 3'-O-sialilolaktozę

Info

Publication number
PL3277287T3
PL3277287T3 PL16771503.6T PL16771503T PL3277287T3 PL 3277287 T3 PL3277287 T3 PL 3277287T3 PL 16771503 T PL16771503 T PL 16771503T PL 3277287 T3 PL3277287 T3 PL 3277287T3
Authority
PL
Poland
Prior art keywords
sialyllactose
mixtures
human milk
milk oligosaccharides
oligosaccharides
Prior art date
Application number
PL16771503.6T
Other languages
English (en)
Inventor
Elise Champion
Bruce Mcconnell
Gyula Dekany
Original Assignee
Glycom A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycom A/S filed Critical Glycom A/S
Publication of PL3277287T3 publication Critical patent/PL3277287T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06Aminosugars
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/14Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01018Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PL16771503.6T 2015-03-31 2016-03-31 Mieszaniny oligosacharydów mleka ludzkiego zawierające 3'-O-sialilolaktozę PL3277287T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15162024 2015-03-31
EP15162014 2015-03-31
PCT/IB2016/051823 WO2016157108A1 (en) 2015-03-31 2016-03-31 Mixtures of human milk oligosaccharides comprising 3 '-o-sialyllactose

Publications (1)

Publication Number Publication Date
PL3277287T3 true PL3277287T3 (pl) 2024-04-22

Family

ID=57003976

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16771503.6T PL3277287T3 (pl) 2015-03-31 2016-03-31 Mieszaniny oligosacharydów mleka ludzkiego zawierające 3'-O-sialilolaktozę

Country Status (7)

Country Link
US (2) US10588917B2 (pl)
EP (1) EP3277287B8 (pl)
CN (2) CN115300517A (pl)
DK (1) DK3277287T3 (pl)
ES (1) ES2971093T3 (pl)
PL (1) PL3277287T3 (pl)
WO (1) WO2016157108A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2971093T3 (es) 2015-03-31 2024-06-03 Glycom As Mezclas de oligosacáridos de la leche humana que comprenden 3'-O-sialilactosa
WO2019003133A1 (en) 2017-06-30 2019-01-03 Glycom A/S PURIFICATION OF OLIGOSACCHARIDES
WO2021079921A1 (ja) * 2019-10-25 2021-04-29 ライオン株式会社 口腔内の病原性細菌に対する生育抑制剤、口腔内の菌叢改善剤及び口腔用組成物
CN117858693A (zh) * 2021-08-24 2024-04-09 帝斯曼知识产权资产管理有限公司 至少一种人乳低聚糖的新颖用途
CN113899827A (zh) * 2021-09-29 2022-01-07 中国科学院合肥物质科学研究院 一种3’-唾液酸乳糖的检测方法及其应用
EP4418878A1 (en) 2021-10-18 2024-08-28 DSM IP Assets B.V. A method for providing an amorphous hmo product by drying
WO2024042235A1 (en) * 2022-08-25 2024-02-29 Dsm Ip Assets B.V. Hybrid method for producing complex hmos

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0686684A (ja) 1992-05-26 1994-03-29 Monsanto Co シアロ抱合体の合成
US6821756B2 (en) * 1996-09-17 2004-11-23 Kyowa Hakko Kogyo Co., Ltd. Processes for reproducing sugar nucleotides and complex carbohydrates
FR2796082B1 (fr) 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
DE19958985A1 (de) 1999-12-07 2001-06-13 Nutricia Nv Oligosaccharidmischung
DE10147100A1 (de) 2001-09-25 2003-04-17 Numico Res B V Antiinfektive Kohlenhydrate
MY148510A (en) 2006-03-09 2013-04-30 Centre Nat Rech Scient Method for producing sialylated oligosaccharides
EP2060257A1 (en) 2007-11-08 2009-05-20 Nestec S.A. Prevention and treatment of secondary infections following viral infection
WO2009155665A1 (en) 2008-06-26 2009-12-30 Central Northern Adelaide Health Service Methods and compositions for treating pathological infections
KR101218893B1 (ko) 2009-03-05 2013-01-09 닛산 지도우샤 가부시키가이샤 쌍극형 2차 전지 및 그 제조 방법
US9012625B2 (en) 2009-04-07 2015-04-21 Glycom A/S Method for the synthesis of a trisaccharide
US8993740B2 (en) 2010-02-19 2015-03-31 Glycom A/S Method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt) containing N-acetyllactosamine
CA2805501A1 (en) * 2010-07-16 2012-01-19 Glycom A/S Synthesis of new sialooligosaccharide derivatives
EP2454948A1 (en) * 2010-11-23 2012-05-23 Nestec S.A. Oligosaccharide mixture and food product comprising this mixture, especially infant formula
BR112013015951A2 (pt) * 2010-12-31 2018-07-10 Abbott Lab composições nutricionais compreendendo oligossacarídeos e nucleotídeos de leite humano e usos destas para tratar e/ou prevenir infecção viral entérica.
EP2522232A1 (en) * 2011-05-13 2012-11-14 Nestec S.A. Nutritional products comprising human milk oligosaccharides and methods for manufacture thereof
KR20140036227A (ko) 2011-05-13 2014-03-25 글리콤 에이/에스 모유 올리고사카라이드(hmo) 또는 그의 전구체의 생성 방법
CA2835989A1 (en) 2011-05-13 2012-11-22 Glycom A/S Diversification of human milk oligosaccharides (hmos) or precursors thereof
US20140323705A1 (en) 2011-05-13 2014-10-30 Markus Hederos Manufacture of lacto-n-tetraose
EP2760875A4 (en) 2011-09-30 2015-08-26 Glycom As SYNTHESIS OF HMO NUCLEAR STRUCTURES
WO2013091660A1 (en) 2011-12-23 2013-06-27 Glycom A/S A method for obtaining crystalline lacto-n-tetraose and lacto-n-neotetraose precursors and mixtures thereof
EP2828275B1 (en) 2012-03-20 2017-03-01 Glycom A/S Synthesis of the trisaccharide 3-o-fucosyllactose and intermediates thereof
US20150064220A1 (en) 2012-03-27 2015-03-05 Abbott Laboratories Methods for modulating cell-mediated immunity using human milk oligosaccharides
PL2999358T3 (pl) 2013-05-22 2021-12-20 Glycom A/S Syntetyczna mieszanina oligosacharydów do leczenia mikrobioty ssaka
DK2845905T3 (da) 2013-09-10 2021-06-14 Chr Hansen Hmo Gmbh Fremstilling af oligosaccharider
US9492473B2 (en) * 2015-01-26 2016-11-15 Kaleido Biosciences, Inc. Glycan therapeutics and related methods thereof
ES2971093T3 (es) 2015-03-31 2024-06-03 Glycom As Mezclas de oligosacáridos de la leche humana que comprenden 3'-O-sialilactosa

Also Published As

Publication number Publication date
EP3277287B1 (en) 2023-11-22
US20180078574A1 (en) 2018-03-22
US10588917B2 (en) 2020-03-17
EP3277287A1 (en) 2018-02-07
EP3277287B8 (en) 2023-12-27
US11173171B2 (en) 2021-11-16
CN107530366A (zh) 2018-01-02
US20200281954A1 (en) 2020-09-10
DK3277287T3 (da) 2024-01-08
ES2971093T3 (es) 2024-06-03
EP3277287A4 (en) 2018-12-26
CN115300517A (zh) 2022-11-08
WO2016157108A1 (en) 2016-10-06

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