DK3441468T3 - Afgivelsesfremgangsmåder og sammensætninger til nukleasemedieret genom-manipulation - Google Patents

Afgivelsesfremgangsmåder og sammensætninger til nukleasemedieret genom-manipulation Download PDF

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DK3441468T3
DK3441468T3 DK18192631.2T DK18192631T DK3441468T3 DK 3441468 T3 DK3441468 T3 DK 3441468T3 DK 18192631 T DK18192631 T DK 18192631T DK 3441468 T3 DK3441468 T3 DK 3441468T3
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nuclease
compositions
delivery methods
mediated genome
genome manipulation
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Michael C Holmes
Jianbin Wang
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Sangamo Therapeutics Inc
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK18192631.2T 2013-10-17 2014-10-16 Afgivelsesfremgangsmåder og sammensætninger til nukleasemedieret genom-manipulation DK3441468T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361892348P 2013-10-17 2013-10-17
US201462033424P 2014-08-05 2014-08-05
EP14854505.6A EP3058072B1 (en) 2013-10-17 2014-10-16 Delivery methods and compositions for nuclease-mediated genome engineering

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DK3441468T3 true DK3441468T3 (da) 2021-07-26

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US (2) US9957526B2 (enExample)
EP (2) EP3441468B1 (enExample)
JP (5) JP6646573B2 (enExample)
CN (3) CN110713995B (enExample)
AU (3) AU2014337248B2 (enExample)
CA (2) CA3194037A1 (enExample)
DK (1) DK3441468T3 (enExample)
ES (1) ES2881473T3 (enExample)
IL (3) IL244796A0 (enExample)
WO (1) WO2015057980A1 (enExample)

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