AU2014337248B2 - Delivery methods and compositions for nuclease-mediated genome engineering - Google Patents

Delivery methods and compositions for nuclease-mediated genome engineering Download PDF

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Publication number
AU2014337248B2
AU2014337248B2 AU2014337248A AU2014337248A AU2014337248B2 AU 2014337248 B2 AU2014337248 B2 AU 2014337248B2 AU 2014337248 A AU2014337248 A AU 2014337248A AU 2014337248 A AU2014337248 A AU 2014337248A AU 2014337248 B2 AU2014337248 B2 AU 2014337248B2
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cells
cell
gene
nuclease
donor
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AU2014337248A1 (en
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Michael C. Holmes
Jianbin Wang
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Sangamo Therapeutics Inc
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Sangamo Therapeutics Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
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  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
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  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2014337248A 2013-10-17 2014-10-16 Delivery methods and compositions for nuclease-mediated genome engineering Ceased AU2014337248B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2020213379A AU2020213379B2 (en) 2013-10-17 2020-08-07 Delivery Methods And Compositions For Nuclease-Mediated Genome Engineering
AU2022271447A AU2022271447A1 (en) 2013-10-17 2022-11-17 Delivery Methods And Compositions For Nuclease-Mediated Genome Engineering

Applications Claiming Priority (5)

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US201361892348P 2013-10-17 2013-10-17
US61/892,348 2013-10-17
US201462033424P 2014-08-05 2014-08-05
US62/033,424 2014-08-05
PCT/US2014/060931 WO2015057980A1 (en) 2013-10-17 2014-10-16 Delivery methods and compositions for nuclease-mediated genome engineering

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AU2014337248A1 AU2014337248A1 (en) 2016-04-21
AU2014337248B2 true AU2014337248B2 (en) 2020-09-24

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AU2020213379A Ceased AU2020213379B2 (en) 2013-10-17 2020-08-07 Delivery Methods And Compositions For Nuclease-Mediated Genome Engineering
AU2022271447A Abandoned AU2022271447A1 (en) 2013-10-17 2022-11-17 Delivery Methods And Compositions For Nuclease-Mediated Genome Engineering

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US (2) US9957526B2 (enExample)
EP (2) EP3441468B1 (enExample)
JP (5) JP6646573B2 (enExample)
CN (3) CN110713995B (enExample)
AU (3) AU2014337248B2 (enExample)
CA (2) CA3194037A1 (enExample)
DK (1) DK3441468T3 (enExample)
ES (1) ES2881473T3 (enExample)
IL (3) IL244796A0 (enExample)
WO (1) WO2015057980A1 (enExample)

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