DK3290052T3 - Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2 - Google Patents

Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2 Download PDF

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Publication number
DK3290052T3
DK3290052T3 DK17191118.3T DK17191118T DK3290052T3 DK 3290052 T3 DK3290052 T3 DK 3290052T3 DK 17191118 T DK17191118 T DK 17191118T DK 3290052 T3 DK3290052 T3 DK 3290052T3
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DK
Denmark
Prior art keywords
growth factor
monoclonal antibodies
antibodies against
factor receptor
fibroblast growth
Prior art date
Application number
DK17191118.3T
Other languages
English (en)
Inventor
Jin Kim Kyung
Wei-Meng Zhao
Hangil Park
Original Assignee
Galaxy Biotech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galaxy Biotech Llc filed Critical Galaxy Biotech Llc
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Publication of DK3290052T3 publication Critical patent/DK3290052T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
DK17191118.3T 2008-11-07 2009-11-06 Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2 DK3290052T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11268608P 2008-11-07 2008-11-07
US16487009P 2009-03-30 2009-03-30
EP14188785.1A EP2842573B1 (en) 2008-11-07 2009-11-06 Monoclonal antibodies to Fibroblast Growth Factor receptor 2

Publications (1)

Publication Number Publication Date
DK3290052T3 true DK3290052T3 (da) 2020-02-03

Family

ID=42153600

Family Applications (3)

Application Number Title Priority Date Filing Date
DK14188785.1T DK2842573T3 (da) 2008-11-07 2009-11-06 Monoklonale antistoffer mod fibroblast vækstfaktorreceptor 2
DK09825523.5T DK2365828T3 (da) 2008-11-07 2009-11-06 Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2.
DK17191118.3T DK3290052T3 (da) 2008-11-07 2009-11-06 Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK14188785.1T DK2842573T3 (da) 2008-11-07 2009-11-06 Monoklonale antistoffer mod fibroblast vækstfaktorreceptor 2
DK09825523.5T DK2365828T3 (da) 2008-11-07 2009-11-06 Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2.

Country Status (21)

Country Link
US (8) US8101723B2 (da)
EP (4) EP3290052B1 (da)
JP (7) JP5627591B2 (da)
KR (1) KR101699432B1 (da)
CN (1) CN102131524B (da)
AU (1) AU2009313357B2 (da)
BR (1) BRPI0917315B8 (da)
CA (2) CA2733668C (da)
DK (3) DK2842573T3 (da)
ES (3) ES2523740T3 (da)
HK (3) HK1160012A1 (da)
HR (2) HRP20171640T1 (da)
HU (1) HUE035700T2 (da)
LT (2) LT3290052T (da)
MX (1) MX2011000455A (da)
NO (1) NO2842573T3 (da)
PL (3) PL3290052T3 (da)
PT (3) PT2842573T (da)
RU (1) RU2546254C9 (da)
SI (2) SI2842573T1 (da)
WO (1) WO2010054265A2 (da)

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Also Published As

Publication number Publication date
US10689448B2 (en) 2020-06-23
JP6960485B2 (ja) 2021-11-05
PL3290052T3 (pl) 2020-06-29
HUE035700T2 (en) 2018-05-28
US8101723B2 (en) 2012-01-24
HK1249053A1 (zh) 2018-10-26
JP6342223B2 (ja) 2018-06-13
JP6661734B2 (ja) 2020-03-11
US9382324B2 (en) 2016-07-05
US20160362496A1 (en) 2016-12-15
JP5627591B2 (ja) 2014-11-19
EP2842573A1 (en) 2015-03-04
HRP20171640T1 (hr) 2018-01-12
EP3290052B1 (en) 2019-12-25
JP7301106B2 (ja) 2023-06-30
US9834609B2 (en) 2017-12-05
DK2842573T3 (da) 2017-10-30
BRPI0917315A2 (pt) 2015-11-17
CN102131524A (zh) 2011-07-20
JP2020096615A (ja) 2020-06-25
CA2733668C (en) 2022-08-30
US20120134994A1 (en) 2012-05-31
ES2523740T3 (es) 2014-12-01
US20230242650A1 (en) 2023-08-03
NO2842573T3 (da) 2018-02-24
JP6445496B2 (ja) 2018-12-26
US20140193899A1 (en) 2014-07-10
SI3290052T1 (sl) 2020-07-31
BRPI0917315B1 (pt) 2020-12-08
SI2842573T1 (en) 2018-01-31
US20100196364A1 (en) 2010-08-05
PT3290052T (pt) 2020-02-06
RU2546254C2 (ru) 2015-04-10
EP2365828A2 (en) 2011-09-21
JP2012508184A (ja) 2012-04-05
PL2842573T3 (pl) 2018-04-30
AU2009313357B2 (en) 2015-06-11
CA3166399A1 (en) 2010-05-14
KR20110081141A (ko) 2011-07-13
PT2365828E (pt) 2014-12-12
JP2017019807A (ja) 2017-01-26
JP2019052165A (ja) 2019-04-04
CN102131524B (zh) 2014-05-14
US8603987B2 (en) 2013-12-10
WO2010054265A2 (en) 2010-05-14
ES2770134T3 (es) 2020-06-30
DK2365828T3 (da) 2014-12-08
EP3290052A1 (en) 2018-03-07
HRP20200090T1 (hr) 2020-04-03
US20180094063A1 (en) 2018-04-05
EP2842573B1 (en) 2017-09-27
JP2023116746A (ja) 2023-08-22
KR101699432B1 (ko) 2017-01-24
HK1160012A1 (en) 2012-08-10
LT3290052T (lt) 2020-02-25
US10138301B2 (en) 2018-11-27
PT2842573T (pt) 2017-12-04
RU2011141890A (ru) 2013-04-27
US20200347141A1 (en) 2020-11-05
CA2733668A1 (en) 2010-05-14
ES2646168T3 (es) 2017-12-12
LT2842573T (lt) 2017-12-11
BRPI0917315B8 (pt) 2021-05-25
EP3783024A1 (en) 2021-02-24
JP2022008996A (ja) 2022-01-14
MX2011000455A (es) 2011-02-25
RU2546254C9 (ru) 2015-07-10
PL2365828T3 (pl) 2015-04-30
JP2014240385A (ja) 2014-12-25
EP2365828A4 (en) 2012-06-06
AU2009313357A1 (en) 2010-05-14
HK1207974A1 (en) 2016-02-19
US20190153105A1 (en) 2019-05-23
EP2365828B1 (en) 2014-10-15
WO2010054265A3 (en) 2010-09-16

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