DK3018204T3 - NEW CLASS OF THERAPEUTIC PROTEIN BASED MOLECULES - Google Patents
NEW CLASS OF THERAPEUTIC PROTEIN BASED MOLECULES Download PDFInfo
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- DK3018204T3 DK3018204T3 DK15180371.5T DK15180371T DK3018204T3 DK 3018204 T3 DK3018204 T3 DK 3018204T3 DK 15180371 T DK15180371 T DK 15180371T DK 3018204 T3 DK3018204 T3 DK 3018204T3
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C—CHEMISTRY; METALLURGY
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- C12Y—ENZYMES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
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Landscapes
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| DK05790917.8T DK1786902T3 (en) | 2004-09-10 | 2005-07-21 | New class of therapeutic protein-based molecules |
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| US20100210528A1 (en) * | 1999-03-05 | 2010-08-19 | Leland Shapiro | Compositions, methods and uses for inhibition and/or treatment of influenza infection |
| US8512710B2 (en) * | 2002-11-22 | 2013-08-20 | Ansun Biopharma, Inc. | Class of therapeutic protein based molecules |
| US8084036B2 (en) * | 2002-11-22 | 2011-12-27 | Nexbio, Inc. | Broad spectrum anti-viral therapeutics and prophylaxis |
| US7807174B2 (en) * | 2002-11-22 | 2010-10-05 | Nexbio, Inc. | Class of therapeutic protein based molecules |
| CN101002512B (zh) * | 2004-11-10 | 2013-12-04 | 日立化成株式会社 | 附有粘着辅助剂的金属箔及使用其的印刷配线板 |
| CA2627323A1 (en) * | 2005-10-25 | 2007-05-03 | Mnd Diagnostic Ltd. | Compositions for- detecting of influenza viruses and kits and methods using same |
| AU2015215955B2 (en) * | 2006-01-24 | 2016-12-01 | Ansun Biopharma, Inc. | Technology for preparation of macromolecular microspheres |
| US20070190163A1 (en) | 2006-01-24 | 2007-08-16 | Malaknov Michael P | Technology for preparation of macromolecular microspheres |
| AU2013237761B8 (en) * | 2006-01-24 | 2015-06-04 | Ansun Biopharma, Inc. | Technology for preparation of macromolecular microspheres |
| US8273381B1 (en) * | 2006-04-14 | 2012-09-25 | Auburn University | Compositions for and methods of controlling olfactory responses to odorants |
| US20100143972A1 (en) * | 2006-12-14 | 2010-06-10 | Horswill Alexander R | Method of Making Cyclic Polypeptides with Inteins |
| EP2113027B1 (en) * | 2007-02-20 | 2014-06-18 | DSM IP Assets B.V. | Novel sialidase |
| BRPI0815057B8 (pt) | 2007-08-03 | 2021-05-25 | Romark Laboratories Lc | composto, composição farmacêutica, e, uso de um composto |
| EA021587B1 (ru) | 2009-05-12 | 2015-07-30 | РОМАРК ЛЭБОРЕТЕРИЗ Эл. Си. | Соединения галогеналкилгетероарилбензамида |
| EA030679B1 (ru) * | 2009-06-26 | 2018-09-28 | РОМАРК ЛЭБОРЕТЕРИЗ Эл.Си. | Соединения и способы лечения гриппа |
| EP2459714A1 (en) * | 2009-07-31 | 2012-06-06 | Danisco US Inc. | Proteases with modified pre-pro regions |
| CN102711807A (zh) * | 2009-11-06 | 2012-10-03 | 耐百生物制药有限公司 | 用于在呼吸道中进行治疗和预防的方法、化合物和组合物 |
| JP2015508780A (ja) | 2012-02-17 | 2015-03-23 | アンサン バイオファーマ,インコーポレイテッド | 免疫不全患者のインフルエンザ及びパラインフルエンザウイルスを処置するための方法、化合物、及び組成物 |
| EP2877204A2 (en) * | 2012-06-28 | 2015-06-03 | Ansun Biopharma, Inc. | Microparticle formulations for delivery to the upper and central respiratory tract and methods of manufacture |
| EP2866792A4 (en) | 2012-06-28 | 2016-08-17 | Ansun Biopharma Inc | MICROPARTICLE FORMULATIONS FOR DELIVERY TO LOWER AND CENTRAL RESPIRATORY PATHS AND METHOD OF PREPARING THEM |
| CA2896057C (en) | 2012-12-24 | 2023-03-14 | Maxine Bauzon | Short-acting factor vii polypeptides |
| CN110295114A (zh) * | 2013-03-15 | 2019-10-01 | 安迅生物制药公司 | 蛋白纯化的新颖方法 |
| WO2014197485A1 (en) * | 2013-06-03 | 2014-12-11 | Ansun Biopharma, Inc. | Anti-viral therapeutic for infection of the eye |
| WO2014201034A2 (en) * | 2013-06-10 | 2014-12-18 | Ansun Biopharma, Inc. | Treatment for polyomavirus infection |
| US20160120961A1 (en) * | 2013-06-10 | 2016-05-05 | Ansun Biopharma, Inc. | Treatment of merkel cell polyomavirus infection |
| WO2015184356A1 (en) | 2014-05-30 | 2015-12-03 | Ansun Biopharma, Inc. | Treatment of middle east respiratory syndrome coronavirus |
| WO2016044656A1 (en) | 2014-09-17 | 2016-03-24 | Ansun Biopharma, Inc. | Treatment of infection by human enterovirus d68 |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| WO2016115616A1 (en) * | 2015-01-21 | 2016-07-28 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health | Inhibition of cellular proteases as treatment for influenza |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| SG10202100652VA (en) * | 2015-07-21 | 2021-03-30 | Univ Jefferson | Gene therapies for neurodegenerative disorders targeting ganglioside biosynthetic pathways |
| EP3458085B1 (en) | 2016-05-20 | 2022-12-07 | Octapharma AG | Glycosylated vwf fusion proteins with improved pharmacokinetics |
| US11459398B2 (en) | 2016-07-01 | 2022-10-04 | The Board Of Trustees Of The Leland Stanford Junior University | Conjugates for targeted cell surface editing |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| ES2986557T3 (es) * | 2017-05-26 | 2024-11-11 | Genovis Ab | Enzimas para el análisis de glucanos |
| JP2020533404A (ja) | 2017-09-05 | 2020-11-19 | グラディエーター バイオサイエンシーズ インコーポレイテッド | 細胞内送達法 |
| MX2020007024A (es) | 2018-01-03 | 2020-10-28 | Palleon Pharmaceuticals Inc | Sialidasas humanas recombinantes, proteinas de fusion de sialidasa y metodos para usar las mismas. |
| GB201800274D0 (en) * | 2018-01-08 | 2018-02-21 | Enzymatica Ab | Novel treatments |
| GB201803197D0 (en) | 2018-02-27 | 2018-04-11 | Pneumagen Ltd | Viral treatment |
| CN112739374A (zh) * | 2018-07-20 | 2021-04-30 | 安迅生物制药公司 | 唾液酸酶向癌细胞、免疫细胞和肿瘤微环境的递送 |
| CN109991649B (zh) * | 2019-03-26 | 2021-04-06 | 华中科技大学 | 一种制备无机闪烁体膜的方法 |
| JP7343890B2 (ja) * | 2019-04-26 | 2023-09-13 | 国立大学法人東海国立大学機構 | シアリダーゼ活性を有する酵素剤及びその利用 |
| CN110038122A (zh) * | 2019-05-23 | 2019-07-23 | 武汉真福医药股份有限公司 | 枯草杆菌纤溶酶在治疗支气管炎药物中的应用 |
| US12245754B2 (en) | 2019-07-03 | 2025-03-11 | Aillis Inc. | Pharmaceutical composition for treating influenza virus infections |
| CN111450236B (zh) * | 2020-02-25 | 2023-04-07 | 西北大学 | 一种用于阻断冠状病毒感染的制剂 |
| WO2021217053A1 (en) * | 2020-04-24 | 2021-10-28 | Rezolute, Inc. | Plasma kallikrein inhibitors for the treatment of ards and related conditions |
| US20230218794A1 (en) * | 2020-06-10 | 2023-07-13 | The Penn State Research Foundation | Process and system to lessen human coronavirus transmission and spread |
| WO2022147481A1 (en) | 2020-12-30 | 2022-07-07 | Ansun Biopharma Inc. | Combination therapy of an oncolytic virus delivering a foreign antigen and an engineered immune cell expressing a chimeric receptor targeting the foreign antigen |
| WO2022261290A1 (en) * | 2021-06-09 | 2022-12-15 | Microbial Machines, Inc. | Engineered microorganisms for detection of diseased cells |
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| US3439089A (en) | 1968-03-27 | 1969-04-15 | Merck & Co Inc | Medicated hard candy |
| US5643758A (en) | 1987-03-10 | 1997-07-01 | New England Biolabs, Inc. | Production and purification of a protein fused to a binding protein |
| DE286239T1 (de) * | 1987-03-10 | 1994-02-24 | New England Biolabs Inc | Herstellung und Reinigung eines Proteins, das mit einem Bindungsprotein fusioniert ist. |
| RU2054180C1 (ru) | 1991-08-21 | 1996-02-10 | Жирнов Олег Петрович (н/п) | Способ лечения вирусных респираторных инфекций |
| US5376633A (en) | 1992-09-30 | 1994-12-27 | Lezdey; John | Method for deactivating viruses in blood component containers |
| US5985859A (en) * | 1994-04-14 | 1999-11-16 | The University Of Alabama | Methods of inhibiting bacterial sialidase |
| DE69527924T2 (de) * | 1994-06-14 | 2003-01-09 | Genencor International, Inc. | Hitzebeständige xylanasen |
| SI9620042A (sl) * | 1995-02-27 | 1998-12-31 | Gilead Sciences, Inc. | Novi selektivni inhibitorji virusnih ali bakterijskih neuraminidaz |
| GB9513683D0 (en) * | 1995-07-05 | 1995-09-06 | Ciba Geigy Ag | Products |
| AU5546898A (en) | 1997-01-14 | 1998-08-07 | Hopital Sainte-Justine | Human lysosomal sialidase and therapeutic uses thereof |
| US6251392B1 (en) | 1997-10-20 | 2001-06-26 | Epicyte Pharmaceuticals, Inc. | Epithelial cell targeting agent |
| US6737511B1 (en) | 1999-08-16 | 2004-05-18 | The United States Of America As Represented By The Department Of Health And Human Services | Receptor-mediated uptake of an extracellular BCL-xL fusion protein inhibits apoptosis |
| US20020025320A1 (en) | 1999-08-20 | 2002-02-28 | Prosper Boyaka | Sialidases as mucosal adjuvants |
| CN1405562A (zh) * | 2002-10-24 | 2003-03-26 | 肖洪武 | 一种唾液酸酶测定试剂 |
| US7807174B2 (en) | 2002-11-22 | 2010-10-05 | Nexbio, Inc. | Class of therapeutic protein based molecules |
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| DE10258400A1 (de) * | 2002-12-13 | 2004-06-24 | N.V. Nutricia | Trans-Sialidasen aus Trypanosoma congolense |
| US20070190163A1 (en) | 2006-01-24 | 2007-08-16 | Malaknov Michael P | Technology for preparation of macromolecular microspheres |
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- 2005-07-21 EP EP05790917.8A patent/EP1786902B1/en not_active Expired - Lifetime
- 2005-07-21 PT PT151803715T patent/PT3018204T/pt unknown
- 2005-07-21 DK DK17164276.2T patent/DK3241898T3/en active
- 2005-07-21 EP EP15180371.5A patent/EP3018204B1/en not_active Expired - Lifetime
- 2005-07-21 EP EP19153015.3A patent/EP3530734A1/en not_active Withdrawn
- 2005-07-21 JP JP2007531167A patent/JP4764881B2/ja not_active Expired - Lifetime
- 2005-07-21 CA CA2578050A patent/CA2578050C/en not_active Expired - Lifetime
- 2005-07-21 EP EP17164276.2A patent/EP3241898B1/en not_active Expired - Lifetime
- 2005-07-21 DK DK05790917.8T patent/DK1786902T3/en active
- 2005-07-21 KR KR1020077008112A patent/KR20070064619A/ko not_active Withdrawn
- 2005-07-21 PT PT57909178T patent/PT1786902E/pt unknown
- 2005-07-21 WO PCT/US2005/025831 patent/WO2006031291A2/en not_active Ceased
- 2005-07-21 ES ES17164276T patent/ES2721172T3/es not_active Expired - Lifetime
- 2005-07-21 CA CA2823429A patent/CA2823429C/en not_active Expired - Lifetime
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2007
- 2007-03-07 IL IL181779A patent/IL181779A/en active IP Right Grant
- 2007-04-10 ZA ZA200702915A patent/ZA200702915B/xx unknown
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2008
- 2008-10-22 US US12/256,230 patent/US7645448B2/en not_active Expired - Lifetime
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2010
- 2010-07-05 JP JP2010153231A patent/JP5307082B2/ja not_active Expired - Fee Related
- 2010-09-02 IL IL207957A patent/IL207957A/en active IP Right Grant
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2015
- 2015-09-06 IL IL241227A patent/IL241227B/en active IP Right Grant
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