TR201905393T4 - Terapötik protein temelli moleküllerin yeni bir sınıfı. - Google Patents
Terapötik protein temelli moleküllerin yeni bir sınıfı. Download PDFInfo
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- TR201905393T4 TR201905393T4 TR2019/05393T TR201905393T TR201905393T4 TR 201905393 T4 TR201905393 T4 TR 201905393T4 TR 2019/05393 T TR2019/05393 T TR 2019/05393T TR 201905393 T TR201905393 T TR 201905393T TR 201905393 T4 TR201905393 T4 TR 201905393T4
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- 230000001225 therapeutic effect Effects 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 208000015181 infectious disease Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 230000001717 pathogenic effect Effects 0.000 abstract 3
- 102000005348 Neuraminidase Human genes 0.000 abstract 2
- 108010006232 Neuraminidase Proteins 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 2
- 238000004873 anchoring Methods 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 2
- 230000000172 allergic effect Effects 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 108020001778 catalytic domains Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 230000028709 inflammatory response Effects 0.000 abstract 1
- 230000026683 transduction Effects 0.000 abstract 1
- 238000010361 transduction Methods 0.000 abstract 1
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01018—Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- General Engineering & Computer Science (AREA)
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- Virology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Plant Pathology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Mevcut buluş, patojenik enfeksiyonu önlemek ve tedavi etmek için yeni bileşimler ve yöntemler sağlar. Özel olarak, mevcut buluş, bileşiği bir hedef hücrenin yüzeyine ankraj eden bir ankrajlama alanına ve bir hedef hücrenin bir patojen, örneğin, bir virüs, tarafından enfeksiyonunu önlemek için ekstraselüler olarak etki edebilen bir terapötik alana sahip olan bileşikler sağlar. Mevcut buluş ayrıca, siyalidaz aktivitesine sahip olan, siyalidaz katalitik alanlarına sahip olan protein-temelli bileşikleri içeren terapötik bileşimleri de içerir. Buluşun bileşikleri, patojen enfeksiyonunu tedavi etmek veya önlemek için ve alerjik ve enflamatuvar yanıtları tedavi etmek ve azaltmak için kullanılabilir. Buluş ayrıca, hedef hücrelerin rekombinant virüsler tarafından transdüksiyonunu arttırmak için bileşimler ve yöntemler de sağlar. Bu tarz bileşimler ve yöntemler gen terapisinde kullanılabilir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/939,262 US7807174B2 (en) | 2002-11-22 | 2004-09-10 | Class of therapeutic protein based molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201905393T4 true TR201905393T4 (tr) | 2019-05-21 |
Family
ID=36060467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2019/05393T TR201905393T4 (tr) | 2004-09-10 | 2005-07-21 | Terapötik protein temelli moleküllerin yeni bir sınıfı. |
Country Status (17)
Country | Link |
---|---|
US (2) | US7807174B2 (tr) |
EP (4) | EP3530734A1 (tr) |
JP (2) | JP4764881B2 (tr) |
KR (1) | KR20070064619A (tr) |
CN (2) | CN101426906B (tr) |
AU (1) | AU2005285461B2 (tr) |
BR (1) | BRPI0515646B8 (tr) |
CA (2) | CA2578050C (tr) |
DK (3) | DK3241898T3 (tr) |
ES (3) | ES2626845T3 (tr) |
HK (2) | HK1201562A1 (tr) |
IL (3) | IL181779A (tr) |
PT (3) | PT1786902E (tr) |
RU (1) | RU2468080C2 (tr) |
TR (1) | TR201905393T4 (tr) |
WO (1) | WO2006031291A2 (tr) |
ZA (1) | ZA200702915B (tr) |
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2004
- 2004-09-10 US US10/939,262 patent/US7807174B2/en active Active
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2005
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- 2005-07-21 EP EP19153015.3A patent/EP3530734A1/en not_active Withdrawn
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- 2005-07-21 JP JP2007531167A patent/JP4764881B2/ja active Active
- 2005-07-21 PT PT57909178T patent/PT1786902E/pt unknown
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- 2005-07-21 BR BRPI0515646A patent/BRPI0515646B8/pt active IP Right Grant
- 2005-07-21 WO PCT/US2005/025831 patent/WO2006031291A2/en active Application Filing
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- 2005-07-21 DK DK17164276.2T patent/DK3241898T3/en active
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- 2005-07-21 ES ES17164276T patent/ES2721172T3/es active Active
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2007
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2008
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2015
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2016
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