DK2580236T3 - Muteiner af tåre-lipocalin, der binder til il-4-r-alfa - Google Patents

Muteiner af tåre-lipocalin, der binder til il-4-r-alfa Download PDF

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Publication number
DK2580236T3
DK2580236T3 DK11726380.6T DK11726380T DK2580236T3 DK 2580236 T3 DK2580236 T3 DK 2580236T3 DK 11726380 T DK11726380 T DK 11726380T DK 2580236 T3 DK2580236 T3 DK 2580236T3
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DK
Denmark
Prior art keywords
muteines
lipocaline
alfa
tower
binding
Prior art date
Application number
DK11726380.6T
Other languages
English (en)
Inventor
Alexandra Baehre
Stefan Trentmann
Klaus Kirchfled
Hans-Juergen Christian
Andreas Hohlbaum
Gabriele Matschiner
Original Assignee
Pieris Pharmaceuticals Gmbh
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pieris Pharmaceuticals Gmbh, Astrazeneca Ab filed Critical Pieris Pharmaceuticals Gmbh
Application granted granted Critical
Publication of DK2580236T3 publication Critical patent/DK2580236T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DK11726380.6T 2010-06-08 2011-06-08 Muteiner af tåre-lipocalin, der binder til il-4-r-alfa DK2580236T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35246110P 2010-06-08 2010-06-08
PCT/EP2011/059420 WO2011154420A2 (en) 2010-06-08 2011-06-08 Tear lipocalin muteins binding il-4 r alpha

Publications (1)

Publication Number Publication Date
DK2580236T3 true DK2580236T3 (da) 2019-06-11

Family

ID=44627297

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11726380.6T DK2580236T3 (da) 2010-06-08 2011-06-08 Muteiner af tåre-lipocalin, der binder til il-4-r-alfa

Country Status (22)

Country Link
US (5) US8986951B2 (da)
EP (1) EP2580236B1 (da)
JP (3) JP5902679B2 (da)
CN (3) CN111499725A (da)
AU (1) AU2011263786B2 (da)
CA (1) CA2800026C (da)
CY (1) CY1122339T1 (da)
DK (1) DK2580236T3 (da)
ES (1) ES2729652T3 (da)
HR (1) HRP20190689T1 (da)
HU (1) HUE043835T2 (da)
LT (1) LT2580236T (da)
NZ (1) NZ603562A (da)
PL (1) PL2580236T3 (da)
PT (1) PT2580236T (da)
RS (1) RS58839B1 (da)
RU (1) RU2569745C2 (da)
SG (1) SG186161A1 (da)
SI (1) SI2580236T1 (da)
TR (1) TR201906295T4 (da)
WO (1) WO2011154420A2 (da)
ZA (1) ZA201209160B (da)

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Publication number Publication date
US9687524B2 (en) 2017-06-27
JP2016028604A (ja) 2016-03-03
CN103038249A (zh) 2013-04-10
RU2569745C2 (ru) 2015-11-27
NZ603562A (en) 2014-07-25
AU2011263786A1 (en) 2012-11-29
JP5902679B2 (ja) 2016-04-13
SG186161A1 (en) 2013-01-30
US20170340703A1 (en) 2017-11-30
CN105949301B (zh) 2020-03-27
US8986951B2 (en) 2015-03-24
LT2580236T (lt) 2019-06-25
HUE043835T2 (hu) 2019-09-30
HRP20190689T1 (hr) 2019-06-14
AU2011263786B2 (en) 2014-11-13
US20130085113A1 (en) 2013-04-04
TR201906295T4 (tr) 2019-05-21
US20210196788A1 (en) 2021-07-01
US20150283207A1 (en) 2015-10-08
RS58839B1 (sr) 2019-07-31
CN105949301A (zh) 2016-09-21
PT2580236T (pt) 2019-05-30
CA2800026C (en) 2023-05-09
CN103038249B (zh) 2016-04-13
JP2013537400A (ja) 2013-10-03
US10232014B2 (en) 2019-03-19
AU2011263786A2 (en) 2014-08-21
WO2011154420A3 (en) 2012-12-20
CY1122339T1 (el) 2021-01-27
SI2580236T1 (sl) 2019-08-30
RU2012150766A (ru) 2014-07-20
ZA201209160B (en) 2014-01-29
US20190240289A1 (en) 2019-08-08
EP2580236B1 (en) 2019-04-03
ES2729652T3 (es) 2019-11-05
WO2011154420A2 (en) 2011-12-15
EP2580236A2 (en) 2013-04-17
JP6766194B2 (ja) 2020-10-07
CN111499725A (zh) 2020-08-07
JP2019115342A (ja) 2019-07-18
CA2800026A1 (en) 2011-12-15
US10898545B2 (en) 2021-01-26
PL2580236T3 (pl) 2019-09-30

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