DK2513119T3 - 3,4,4a,10b-tetrahydro-1h-thiopyrano-[4,3-c]isoquinolin derivater - Google Patents
3,4,4a,10b-tetrahydro-1h-thiopyrano-[4,3-c]isoquinolin derivaterInfo
- Publication number
- DK2513119T3 DK2513119T3 DK10790569.7T DK10790569T DK2513119T3 DK 2513119 T3 DK2513119 T3 DK 2513119T3 DK 10790569 T DK10790569 T DK 10790569T DK 2513119 T3 DK2513119 T3 DK 2513119T3
- Authority
- DK
- Denmark
- Prior art keywords
- thiopyrano
- derivates
- isoquinoline
- tetrahydro
- isoquinoline derivates
- Prior art date
Links
- ZQCSTHXMOLTGJA-UHFFFAOYSA-N 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c]isoquinoline Chemical compound N1=CC2=CC=CC=C2C2C1CCSC2 ZQCSTHXMOLTGJA-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
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- Public Health (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Pulmonology (AREA)
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- Ophthalmology & Optometry (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09179982 | 2009-12-18 | ||
| US31555210P | 2010-03-19 | 2010-03-19 | |
| PCT/EP2010/069704 WO2011073231A1 (en) | 2009-12-18 | 2010-12-15 | 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4, 3-c] ISOQUINOLINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2513119T3 true DK2513119T3 (da) | 2014-10-06 |
Family
ID=41718903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10790569.7T DK2513119T3 (da) | 2009-12-18 | 2010-12-15 | 3,4,4a,10b-tetrahydro-1h-thiopyrano-[4,3-c]isoquinolin derivater |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9018175B2 (https=) |
| EP (2) | EP2813509B1 (https=) |
| JP (1) | JP5645961B2 (https=) |
| KR (1) | KR20120123313A (https=) |
| CN (1) | CN102652136B (https=) |
| AR (1) | AR079451A1 (https=) |
| AU (1) | AU2010332955B8 (https=) |
| BR (1) | BR112012014058A8 (https=) |
| CA (1) | CA2784013A1 (https=) |
| CO (1) | CO6551705A2 (https=) |
| DK (1) | DK2513119T3 (https=) |
| EA (1) | EA023212B1 (https=) |
| ES (2) | ES2505290T3 (https=) |
| GE (1) | GEP20146105B (https=) |
| HR (1) | HRP20140893T1 (https=) |
| ME (1) | ME01914B (https=) |
| MX (1) | MX2012006696A (https=) |
| NZ (1) | NZ601115A (https=) |
| PH (1) | PH12012501125A1 (https=) |
| PL (1) | PL2513119T3 (https=) |
| PT (1) | PT2513119E (https=) |
| RS (1) | RS53544B1 (https=) |
| SG (2) | SG196785A1 (https=) |
| SI (1) | SI2513119T1 (https=) |
| SM (1) | SMT201400185B (https=) |
| TW (1) | TWI468411B (https=) |
| UA (1) | UA107689C2 (https=) |
| WO (1) | WO2011073231A1 (https=) |
| ZA (1) | ZA201204135B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2577777B1 (en) | 2010-06-07 | 2016-12-28 | Sapurast Research LLC | Rechargeable, high-density electrochemical device |
| CN103501776A (zh) * | 2011-02-17 | 2014-01-08 | 西普拉有限公司 | 甘罗铵与β2激动剂的组合物 |
| EP2721036B1 (en) | 2011-06-15 | 2015-07-22 | Takeda GmbH | Novel 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c]isoquinoline compounds |
| WO2014016548A2 (en) * | 2012-07-27 | 2014-01-30 | Cipla Limited | Pharmaceutical composition |
| WO2014090990A1 (en) * | 2012-12-13 | 2014-06-19 | Ludwig Aigner | Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease |
| WO2014117947A1 (en) | 2013-02-04 | 2014-08-07 | Grünenthal GmbH | 4-amino substituted condensed pyrimidine compounds as pde4 inhibitors |
| BR112015019276A2 (pt) | 2013-02-19 | 2017-07-18 | Pfizer | compostos de azabenzimidazol como inibidores de isoenzimas de pde4 para o tratamento de distúrbios do snc e outros distúrbios |
| WO2016012896A1 (en) | 2014-07-24 | 2016-01-28 | Pfizer Inc. | Pyrazolopyrimidine compounds |
| MD20170011A2 (ro) | 2014-08-06 | 2017-08-31 | Pfizer Inc. | Compuşi imidazopiridazinici |
| WO2017089347A1 (en) | 2015-11-25 | 2017-06-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas |
| WO2022006470A1 (en) | 2020-07-01 | 2022-01-06 | Vanderbilt University | Methods of treatment for a kidney disease |
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| US3899494A (en) | 1970-05-13 | 1975-08-12 | Sandoz Ltd | Substituted 6-phenyl benzo-naphthyridines |
| DE2047465A1 (de) | 1970-09-26 | 1972-03-30 | Farbwerke Hoechst AG, vorm Meister Lucius & Bruning, 6000 Frankfurt | Neue Oxdiazole und Verfahren zu lh rer Herstellung |
| CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| JPH01213284A (ja) | 1988-02-22 | 1989-08-28 | Sankyo Co Ltd | チエノピリミジン−２，４−ジオン誘導体 |
| GB8828477D0 (en) | 1988-12-06 | 1989-01-05 | Riker Laboratories Inc | Medical aerosol formulations |
| ATE111364T1 (de) | 1989-05-31 | 1994-09-15 | Fisons Plc | Medikament und inhalationsvorrichtung dafür. |
| GB8921222D0 (en) | 1989-09-20 | 1989-11-08 | Riker Laboratories Inc | Medicinal aerosol formulations |
| IL97065A (en) | 1990-02-02 | 1994-01-25 | Fisons Plc | Repellent preparations for aerosol |
| DE4003272A1 (de) | 1990-02-03 | 1991-08-08 | Boehringer Ingelheim Kg | Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen |
| DE69131867T2 (de) | 1990-03-23 | 2000-05-18 | Minnesota Mining And Mfg. Co., Saint Paul | Anwendung von löslichen fluorhaltigen Tensiden zur Herstellung von Aerosol-Präparaten mit dosierter Abgabe |
| ATE114112T1 (de) | 1990-10-18 | 1994-12-15 | Minnesota Mining & Mfg | Aerosolzubereitung, die beclometason 17,21- dipropionat enthält. |
| AU650953B2 (en) | 1991-03-21 | 1994-07-07 | Novartis Ag | Inhaler |
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| ES2260299T3 (es) | 2000-10-09 | 2006-11-01 | 3M Innovative Properties Company | Formulaciones medicinales en aerosol. |
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| GB0202254D0 (en) | 2002-01-31 | 2002-03-20 | Pfizer Ltd | Prevention of scarring |
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| MXPA06012279A (es) | 2004-04-23 | 2007-01-31 | Celgene Corp | Metodos de uso y composiciones que comprenden moduladores de pde4 para el tratamiento y manejo de la hipertension pulmonar. |
| ATE508130T1 (de) | 2004-09-08 | 2011-05-15 | Nycomed Gmbh | 3-oxa-10-aza-phenanthrene als pde4- oder pde3/4- inhibitoren |
| EP1791847A2 (en) | 2004-09-08 | 2007-06-06 | Altana Pharma AG | Novel 3-thia-10-aza-phenanthrene derivatives |
| CA2588768A1 (en) | 2004-11-17 | 2006-05-26 | Kissei Pharmaceutical Co., Ltd. | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both |
| CA2599368A1 (en) | 2005-03-09 | 2006-09-14 | Nycomed Gmbh | Amido-substituted 6-phenylphenanthridines |
| MX2009011089A (es) | 2007-04-23 | 2009-10-30 | Sanofi Aventis | Derivados de quinolina-carboxamida en calidad de antagonistas de p2y12. |
| EP2721036B1 (en) * | 2011-06-15 | 2015-07-22 | Takeda GmbH | Novel 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c]isoquinoline compounds |
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- 2010-12-15 WO PCT/EP2010/069704 patent/WO2011073231A1/en not_active Ceased
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- 2010-12-15 CA CA2784013A patent/CA2784013A1/en not_active Abandoned
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