DK2436378T3 - Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger - Google Patents

Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger

Info

Publication number
DK2436378T3
DK2436378T3 DK11191733T DK11191733T DK2436378T3 DK 2436378 T3 DK2436378 T3 DK 2436378T3 DK 11191733 T DK11191733 T DK 11191733T DK 11191733 T DK11191733 T DK 11191733T DK 2436378 T3 DK2436378 T3 DK 2436378T3
Authority
DK
Denmark
Prior art keywords
coated
film
pharmaceutical compositions
containing compounds
granulated calcium
Prior art date
Application number
DK11191733T
Other languages
English (en)
Inventor
Jan Yngvar Piene
Original Assignee
Takeda Nycomed As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Nycomed As filed Critical Takeda Nycomed As
Application granted granted Critical
Publication of DK2436378T3 publication Critical patent/DK2436378T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A23L29/37—Sugar alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31844—Of natural gum, rosin, natural oil or lac
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31971—Of carbohydrate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK11191733T 2005-12-07 2006-12-07 Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger DK2436378T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200501736 2005-12-07
DKPA200601203 2006-09-15
US85013006P 2006-10-06 2006-10-06
EP20060818155 EP1962807B1 (en) 2005-12-07 2006-12-07 Film-coated and/or granulated calcium-containing compounds and use thereof in pharmaceutical compositions

Publications (1)

Publication Number Publication Date
DK2436378T3 true DK2436378T3 (da) 2014-11-03

Family

ID=59285472

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06818155T DK1962807T3 (da) 2005-12-07 2006-12-07 Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger
DK11191733T DK2436378T3 (da) 2005-12-07 2006-12-07 Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK06818155T DK1962807T3 (da) 2005-12-07 2006-12-07 Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger

Country Status (25)

Country Link
US (2) US8846101B2 (da)
EP (2) EP2436378B1 (da)
JP (2) JP5368802B2 (da)
KR (2) KR101451954B1 (da)
CN (1) CN101355927B (da)
AR (1) AR058297A1 (da)
AU (1) AU2006322453B2 (da)
BR (1) BRPI0619572B8 (da)
CA (1) CA2631827C (da)
CY (2) CY1115660T1 (da)
DK (2) DK1962807T3 (da)
EA (1) EA018744B1 (da)
ES (2) ES2522544T3 (da)
GE (1) GEP20125596B (da)
HK (1) HK1126122A1 (da)
IL (2) IL191632A (da)
NO (2) NO340899B1 (da)
NZ (1) NZ568429A (da)
PL (2) PL1962807T3 (da)
PT (2) PT2436378E (da)
SI (2) SI2436378T1 (da)
TW (1) TWI519321B (da)
UA (1) UA95093C2 (da)
WO (1) WO2007065441A1 (da)
ZA (1) ZA200804510B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE534876T1 (de) * 2004-09-21 2011-12-15 Iglesias Vives Joan Verfahren und maschine zum sintern und/oder trocknen von pulvermaterialien unter verwendung von infrarotstrahlung
GB2447019A (en) * 2007-02-27 2008-09-03 Apatech Ltd Bone-replacement material
DE102008012015A1 (de) * 2008-03-01 2009-09-10 Südzucker AG Mannheim/Ochsenfurt Verbesserte Isomalt-haltige Komprimate und Verfahren zu ihrer Herstellung
DE102008047910A1 (de) 2008-09-19 2010-03-25 Molkerei Meggle Wasserburg Gmbh & Co. Kg Tablettierhilfsstoff auf Laktose- und Cellulosebasis
EA021707B1 (ru) * 2008-11-17 2015-08-31 Такеда Никомед Ас Способ получения таблетки, содержащей по меньшей мере 50% мас./мас. карбоната кальция, и таблетка, полученная этим способом
EP2210595A1 (en) * 2009-01-14 2010-07-28 LEK Pharmaceuticals d.d. Active coating of pharmaceutical dosage forms
WO2011048144A1 (en) * 2009-10-20 2011-04-28 Herbonis Ag Composition comprising solanum glaucophyllum for preventing and/or treating hypocalcaemia and for stabilizing blood calcium levels
TR200908237A2 (tr) 2009-11-02 2011-05-23 Bi̇lgi̇ç Mahmut Kalsiyum ve D vitamini içeren farmasötik bileşimler.
US20110300216A1 (en) * 2010-06-03 2011-12-08 First Eric R Chewable, swallowable and effervescent solid dosage form for oral delivery of pharmaceutical actives
US8821942B1 (en) * 2011-04-06 2014-09-02 Access Business Group International Llc Highly compressible, low density ground calcium carbonate granulation and a related method of preparation
AR089857A1 (es) * 2012-02-02 2014-09-24 Glaxosmithkline Llc Comprimido antiacido para refrescar el aliento
US10092518B2 (en) 2012-04-10 2018-10-09 Alpina Laudanum Institute Of Phytopharmaceutical Sciences Ag Wet granulation process and granulate material comprising Arabic gum
CN102823872B (zh) * 2012-08-22 2014-01-15 安徽泰格生物技术股份有限公司 包膜乳酸钙颗粒及其制备方法
EP2964261A4 (en) * 2013-03-07 2016-07-27 Amneal Pharmaceuticals Llc STABILIZATION OF MOISTURE-SENSITIVE DRUGS
US8728428B1 (en) 2013-03-13 2014-05-20 Carbon Engineering Limited Partnership Recovering a caustic solution via calcium carbonate crystal aggregates
US9637393B2 (en) * 2014-05-19 2017-05-02 Carbon Engineering Limited Partnership Recovering a caustic solution via calcium carbonate crystal aggregates
CA2956050C (en) 2014-07-31 2023-09-12 Amorphical Ltd. Non-aqueous liquid and semi-solid formulations of amorphous calcium carbonate
EP3193843A1 (en) * 2014-09-17 2017-07-26 Steerlife India Private Limited Effervescent composition and method of making it
KR101683635B1 (ko) 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
CN106265725B (zh) * 2015-05-14 2021-02-09 北京科信必成医药科技发展有限公司 一种碳酸钙掩味颗粒剂及其制备方法
AU2016294583B2 (en) * 2015-07-14 2021-02-04 Specialty Operations France Agricultural adjuvant compositions of oil/surfactant/salt emulsions and methods for use
CN106420808B (zh) * 2015-08-11 2019-07-19 北京远方通达医药技术有限公司 一种含有维生素d3和碳酸钙的制剂及其制备方法
KR20180062063A (ko) 2016-11-30 2018-06-08 (주) 메티메디제약 서방형 항암용 약학 조성물
RU2643922C1 (ru) * 2017-06-07 2018-02-06 федеральное государственное бюджетное образовательное учреждение высшего образования Кубанский государственный медицинский университет Министерства Здравоохранения Российской Федерации (ФГБОУ ВО КубГМУ, Минздрава России) Гидрогель для замещения дефектов биологических тканей
KR101856905B1 (ko) * 2017-08-21 2018-06-11 박삼목 염화칼슘 성분이 함유된 리필용 습기제거제 및 이를 이용한 보충용 용기
EP3737363A4 (en) 2018-01-12 2021-10-20 Metimedi Pharmaceuticals Co., Ltd METHODS OF TREATMENT OF CHRONIC INFLAMMATORY DISEASES
CN108420797B (zh) * 2018-05-09 2022-05-03 南京海融制药有限公司 维生素d类似物制剂及其制备方法
CA3107696A1 (en) * 2018-10-04 2020-04-09 Chemische Fabrik Budenheim Kg Spherical beads for use in producing pharmaceutically active pellets
KR102155235B1 (ko) * 2020-01-13 2020-09-11 주식회사 뉴팜 탄산분말을 이용한 기능성 식품
GB202001237D0 (en) * 2020-01-29 2020-03-11 Sisteks D O O Granular pharmaceutical product for oral administration from a pre-filled straw and method of manufacturing such pharmaceutical product
CN111973574B (zh) * 2020-07-28 2022-04-08 健民药业集团股份有限公司 一种维生素d类似物微球及其制备方法
US20240261290A1 (en) * 2023-02-06 2024-08-08 Boehringer Ingelheim International Gmbh Pharmaceutical composition comprising 7-(4-chlorobenzyl)-1-(3-hydroxypropyl)-3-methyl-8-(3-(trifluoromethoxy)-phenoxy)-3,7-dihydro-1h-purine-2,6-dione

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2332470A (en) * 1969-12-15 1972-06-15 Sandoz Patents Limited Improvements in or relating to organic compounds
US4162319A (en) * 1974-08-28 1979-07-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Ring substituted pyrazino-isoquinoline derivatives and their preparation
DE2441261A1 (de) * 1974-08-28 1976-03-18 Merck Patent Gmbh Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung
CA1165242A (en) * 1981-07-01 1984-04-10 Hovsep Simonian Compressed and formed alkaline component suitable for use in buffered acetylsalicylic acid product
US4664915A (en) * 1981-07-01 1987-05-12 Bristol-Myers Company Compressed and formed alkaline component suitable for use in buffered aspirin product
US4684534A (en) 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
CA1279574C (en) * 1985-04-17 1991-01-29 Jeffrey L. Finnan Process for lubricating water-soluble vitamin powders
US5198227A (en) * 1990-01-22 1993-03-30 Mcneil-Ppc, Inc. Dual subcoated simulated capsule medicament
DE4006734C1 (da) * 1990-03-03 1991-07-25 Benckiser-Knapsack Gmbh, 6802 Ladenburg, De
US5204115A (en) 1990-12-12 1993-04-20 Suomen Xyrofin Oy Directly compressible xylitol and method
JP2995226B2 (ja) 1992-03-03 1999-12-27 日本ワイスレダリー株式会社 カルシウム含有チユアブル錠
US5965162A (en) * 1993-09-10 1999-10-12 Fuisz Technologies Ltd. Process for forming chewable quickly dispersing multi-vitamin preparation and product therefrom
US5405623A (en) 1993-09-22 1995-04-11 Wm. Wrigley Jr. Company Chewing gum compositions and methods for manufacturing same
DE4427137B4 (de) 1993-10-07 2007-08-23 Degussa Gmbh Fällungskieselsäure
FR2717387B1 (fr) * 1994-03-17 1996-10-18 Hi Pharmtech Procédé de fabrication de comprimés à croquer à base de troxérutine, de carbonate de calcium, de phosphate de calcium, d'aspartate d'arginine, de glutamate d'arginine d'amoxicilline.
FR2724844B1 (fr) 1994-09-23 1997-01-24 Innothera Lab Sa Association therapeutique vitamino-calcique, son procede d'obtention et son utilisation
US6716454B2 (en) * 1994-09-23 2004-04-06 Laboratorie Innothera, Société Anonyme Therapeutic combination of vitamin and calcium in unitary galenic tablet form, a method of obtaining it, and the use thereof
US5846506A (en) * 1994-10-07 1998-12-08 Degussa Aktiengesellschaft Precipitated silicas
DE19617487A1 (de) 1996-05-02 1997-11-06 Merck Patent Gmbh Geschmacksverbesserung von Arzneimittelwirkstoffen
AU733032C (en) 1996-06-14 2002-01-03 Kyowa Hakko Kirin Co., Ltd. Intraorally rapidly disintegrable tablet
JPH10108647A (ja) * 1996-10-08 1998-04-28 Meiji Seika Kaisha Ltd 胃切除術後患者用ミネラル補給材
FR2762217B1 (fr) 1997-04-16 2000-09-29 Besins Iscovesco Lab Preparation solide vitamino-calcique, son procede d'obtention et son utilisation
US5939091A (en) 1997-05-20 1999-08-17 Warner Lambert Company Method for making fast-melt tablets
ITFI970184A1 (it) * 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
CA2305179A1 (en) 1997-09-30 1999-04-08 Daiichi Pharmaceutical Co., Ltd. Oral administration preparation
NZ505123A (en) * 1997-12-19 2003-07-25 Smithkline Beecham Corp Process for manufacturing bite-dispersion tablets by compressing medicaments and other ingredients into granulates then compressing the granulates and other ingredients into tablets, and the tablets thereof
PE20000559A1 (es) * 1998-05-27 2000-07-05 Merck & Co Inc Formulacion de tabletas comprimidas de efavirenz
GB9825033D0 (en) * 1998-11-13 1999-01-13 Nycomed Pharma As Process
ATE276199T1 (de) * 1999-02-03 2004-10-15 Biosante Pharmaceuticals Inc Methoden zur herstellung von therapeutische kalzium-phosphat partikeln
DE19927537A1 (de) 1999-06-16 2000-12-21 Merck Patent Gmbh Sprühtrocknungsanlage und Verfahren zu ihrer Verwendung
EP1116485A3 (de) 2000-01-10 2002-01-16 Gerhard Dr. Gergely Instant-Granulat und Verfahren zu seiner Herstellung
GB0003782D0 (en) * 2000-02-17 2000-04-05 Dumex Ltd As Process
DE50011442D1 (de) 2000-02-18 2005-12-01 Glatt Ingtech Gmbh Verfahren zur Herstellung von Vollwaschmitteln und Vollwaschmittelkomponenten
SK284948B6 (sk) 2000-04-06 2006-03-02 Zentiva, A. S. Liečivý prípravok s obsahom vápnika alebo zmesi vápnika a vitamínu D, alebo zmesi vápnika a horčíka v novej liekovej forme
AR028064A1 (es) 2000-05-03 2003-04-23 Omnia Fertilizer Ltd Metodo para producir granulos de nitrato de calcio
JP2001316249A (ja) 2000-05-11 2001-11-13 Lion Corp 錠剤型医薬組成物
US6419954B1 (en) * 2000-05-19 2002-07-16 Yamanouchi Pharmaceutical Co., Ltd. Tablets and methods for modified release of hydrophilic and other active agents
JP2002087965A (ja) * 2000-09-14 2002-03-27 Lion Corp 口中崩壊性アスピリン含有錠剤
IT1319685B1 (it) 2000-12-12 2003-10-23 Ursula Mariah Rothlin Formulazioni alimentari ad elevato contenuto di calcio.
US7303763B2 (en) * 2001-02-12 2007-12-04 Watson Laboratories, Inc. Compositions for conjugated estrogens and associated methods
CA2440361A1 (en) * 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co. Ltd. Intraorally rapidly disintegrable preparation
WO2002070013A1 (fr) * 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co., Ltd. Utilisation d'une poudre sechee par atomisation contenant un alcool de sucre
JP3825269B2 (ja) 2001-03-13 2006-09-27 三菱重工業株式会社 ターボクーリングシステム
RU2283651C2 (ru) * 2001-12-21 2006-09-20 Пфайзер Продактс Инк. Способы мокрой грануляции азитромицина
WO2004047810A1 (en) 2002-11-25 2004-06-10 Purdue Research Foundation Mannose-based fast dissolving tablets
JP4578124B2 (ja) * 2003-03-12 2010-11-10 武田薬品工業株式会社 高濃度に活性成分を球形核に付着させた医薬組成物
US8449911B2 (en) * 2003-03-12 2013-05-28 Takeda Pharmaceutical Company Limited Drug composition having active ingredient adhered at high concentration to spherical core
CA2531065A1 (en) 2003-07-10 2005-01-27 Smithkline Beecham Corporation Pharmaceutical compositions
US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
US20050244493A1 (en) 2004-04-30 2005-11-03 Withiam Michael C Rapidly disintegrating tablets comprising calcium carbonate
ES2523148T3 (es) * 2004-05-24 2014-11-21 Takeda Nycomed As Material en forma de partículas que comprende un compuesto que contiene calcio y un alcohol de azúcar
BE1016566A4 (fr) 2004-05-25 2007-02-06 Psaltopoulos Emmanuel Procede pour fournir les besoins quotidiens de l'etre humain en calcium (ca), en vitamine "d" et en vitamine "k" sous forme de pilule a croquer ou a avaler.
US20060068005A1 (en) 2004-09-30 2006-03-30 Pal Laboratories, Inc. Chewable electrolyte tablet
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
ES2255429B1 (es) 2004-10-25 2007-08-16 Italfarmaco, S.A. Composiciones farmaceuticas bucodispersables.
WO2006131806A2 (en) 2005-06-07 2006-12-14 Pfizer Products Inc. Multiparticulates comprising low-solubility drugs and carriers that result in rapid drug release
BE1016895A6 (fr) 2005-12-16 2007-09-04 Psaltopoulos Emmanuel MOLECULE INCORPORANT LE CALCIUM (CA), LA VITAMINE "D" ET LA VITAMINE "K" POUR LA PREVENTION ET LE TRAITEMENT DE l'OSTEOPOROSE AINSI QUE POUR LA PREVENTION DE LA CALCIFICATION VASCULAIRE ET POUR LA PREVENTION DE LA CALCIFICATION DU CARTILAGE DES ARTICULATIONS.
US8859011B2 (en) 2006-05-12 2014-10-14 Particle Dynamics International, Llc Calcium compositions
FI20080346A0 (fi) 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi lisäaineita sisältävän tabletin valmistamiseksi
FI20080351A0 (fi) 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi matalan lääkepitoisuuden tabletin valmistamiseksi
FI20080352A0 (fi) 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi korkean lääkepitoisuuden tabletin valmistamiseksi
KR101472543B1 (ko) 2007-01-16 2014-12-16 코닌클리케 필립스 엔.브이. 혼성 타입의 지향성 단말기를 위한 디바이스 발견
CA2835910C (en) 2007-04-25 2016-06-28 Warner Chilcott Company, Llc Improved vitamin d content uniformity in pharmaceutical dosage forms
WO2008141333A1 (en) 2007-05-14 2008-11-20 Cadbury Adams Usa Llc Taste potentiator compositions in oral delivery systems
CN102046147B (zh) 2007-06-06 2013-03-20 巴斯夫欧洲公司 用于制备快速崩解的片剂的药物配制剂
WO2008148742A2 (de) 2007-06-06 2008-12-11 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
JP2010529073A (ja) 2007-06-06 2010-08-26 ビーエーエスエフ ソシエタス・ヨーロピア チュアブル錠及びトローチ剤製造のための医薬製剤
JP2010529071A (ja) 2007-06-06 2010-08-26 ビーエーエスエフ ソシエタス・ヨーロピア 速崩性錠剤製造のための医薬製剤
WO2009100271A1 (en) 2008-02-07 2009-08-13 Ralph Brown Prevention of micronutrient deficiencies associated with common disabilities in the over 50 adult
FR2928269B1 (fr) 2008-03-05 2011-10-07 Innothera Chouzy Formulation pharmaceutique orale sous forme unitaire de comprime soluble ou dispersible, notamment effervescent, appropriee a une fabrication par compression
US8324191B2 (en) 2008-07-11 2012-12-04 Biolink Life Sciences, Inc Combined calcium, magnesium and vitamin D supplements
US20100068347A1 (en) 2008-09-15 2010-03-18 Yael Policker Nutraceutical sweetener composition

Also Published As

Publication number Publication date
KR20080081020A (ko) 2008-09-05
NO341860B1 (no) 2018-02-12
ES2522544T3 (es) 2014-11-17
EP1962807A1 (en) 2008-09-03
IL191632A (en) 2016-04-21
CN101355927A (zh) 2009-01-28
US20090252805A1 (en) 2009-10-08
BRPI0619572B1 (pt) 2020-11-17
AU2006322453B2 (en) 2013-03-07
EP2436378A1 (en) 2012-04-04
ZA200804510B (en) 2015-04-29
US20150050353A1 (en) 2015-02-19
US8846101B2 (en) 2014-09-30
CA2631827A1 (en) 2007-06-14
NZ568429A (en) 2012-04-27
ES2521640T3 (es) 2014-11-13
AR058297A1 (es) 2008-01-30
KR101451954B1 (ko) 2014-10-16
UA95093C2 (uk) 2011-07-11
PL2436378T3 (pl) 2015-04-30
TW200730184A (en) 2007-08-16
BRPI0619572A2 (pt) 2012-12-11
JP2013209403A (ja) 2013-10-10
JP2009518322A (ja) 2009-05-07
DK1962807T3 (da) 2014-11-03
JP5368802B2 (ja) 2013-12-18
KR101554355B1 (ko) 2015-09-18
CA2631827C (en) 2016-09-13
IL191632A0 (en) 2008-12-29
US9801907B2 (en) 2017-10-31
EA018744B1 (ru) 2013-10-30
PT1962807E (pt) 2014-10-29
NO20170606A1 (no) 2017-04-10
PT2436378E (pt) 2014-10-29
KR20140037278A (ko) 2014-03-26
CY1115660T1 (el) 2017-01-25
NO340899B1 (no) 2017-07-10
WO2007065441A1 (en) 2007-06-14
BRPI0619572A8 (pt) 2017-12-19
EP2436378B1 (en) 2014-08-06
IL244761A0 (en) 2016-05-01
SI2436378T1 (sl) 2014-12-31
CY1115661T1 (el) 2017-01-25
IL244761B (en) 2018-07-31
NO20082903L (no) 2008-07-01
PL1962807T3 (pl) 2015-03-31
CN101355927B (zh) 2013-04-17
HK1126122A1 (en) 2009-08-28
TWI519321B (zh) 2016-02-01
BRPI0619572B8 (pt) 2021-05-25
EP1962807B1 (en) 2014-08-06
AU2006322453A1 (en) 2007-06-14
SI1962807T1 (sl) 2014-12-31
EA200870007A1 (ru) 2009-02-27
GEP20125596B (en) 2012-08-10

Similar Documents

Publication Publication Date Title
DK2436378T3 (da) Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger
DK1894567T3 (da) Ledsagende farmaceutiske midler og anvendelse deraf
DK2114924T3 (da) Co-krystaller og farmaceutiske sammensætninger omfattende disse
DK1890681T3 (da) Törgranuleret sammensætning indeholdende emtricitabin og tenofovir DF
IL190292A (en) History of pyridopyrimidinone and their pharmaceutical preparations
EP1890677A4 (en) PHARMACEUTICAL COMPOSITIONS AND THEIR USE
RU2398586C3 (ru) Фармацевтическая композиция
PL1861387T3 (pl) Pochodne benzoimidazolu i ich kompozycje farmaceutyczne
IL190249A0 (en) Deazapurine derivatives and pharmaceutical compositions containing the same
NO343748B1 (no) Cyklopaminanaloger og farmasøytiske preparater omfattende slike
NO345139B1 (no) Florizinanaloger som inhibitorer av glukosekotransportør 2 og farmasøytisk sammensetning derav
NO20085030L (no) Pyrrolopyrimidinforbindelser og deres anvendelser
DK1883665T3 (da) Polylactidsammensætninger og anvendelser deraf
NO20085420L (no) Farmasøytisk formulering med fenylefrin og preparater for absorpsjon i tykktarmen
IL194404A0 (en) Benzyl phenyl glucopyranoside derivatives and pharmaceutical compositions containing the same
DK1948149T3 (da) Præparat indeholdende metformin og vildagliptin
DK1962873T3 (da) Farmaceutiske sammensætninger omfattende oxalat-reducerende bakterier
DK1827412T3 (da) Sammensætninger til anvendelse i kirurgi
PT1861387E (pt) Derivados de benzimidazol e composições farmacêuticas dos mesmos
DK1968990T3 (da) Vandopløselig benzoazepinforbindelse og farmaceutisk sammensætning deraf
DK2001556T3 (da) Thioninium-forbindelser og anvendelse deraf
DK1858481T3 (da) Ophthalmologiske sammensætninger og anvendelse deraf
DK2068891T3 (da) Sammensætning omfattende krebsdyr gastrolith komponenter, calciumcarbonat og anvendelse deraf
DK1885716T3 (da) Thiazolderivater og anvendelse deraf
IL186102A0 (en) Alpha ketoamide derivatives and pharmaceutical compositions containing the same