DK2336132T3 - Morpholinpurinderivat - Google Patents

Morpholinpurinderivat

Info

Publication number
DK2336132T3
DK2336132T3 DK09820579.2T DK09820579T DK2336132T3 DK 2336132 T3 DK2336132 T3 DK 2336132T3 DK 09820579 T DK09820579 T DK 09820579T DK 2336132 T3 DK2336132 T3 DK 2336132T3
Authority
DK
Denmark
Prior art keywords
morpholinpurinderivat
Prior art date
Application number
DK09820579.2T
Other languages
Danish (da)
English (en)
Inventor
Kazuyuki Sugita
Kiyoshi Nakayama
Masaki Setoguchi
Yuichi Tominaga
Masanori Saitou
Takashi Odagiri
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of DK2336132T3 publication Critical patent/DK2336132T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK09820579.2T 2008-10-14 2009-10-13 Morpholinpurinderivat DK2336132T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008264797 2008-10-14
JP2009121690 2009-05-20
PCT/JP2009/067738 WO2010044401A1 (ja) 2008-10-14 2009-10-13 モルホリノプリン誘導体

Publications (1)

Publication Number Publication Date
DK2336132T3 true DK2336132T3 (da) 2014-04-07

Family

ID=42106564

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09820579.2T DK2336132T3 (da) 2008-10-14 2009-10-13 Morpholinpurinderivat

Country Status (21)

Country Link
US (2) US8097622B2 (enExample)
EP (1) EP2336132B1 (enExample)
JP (1) JP5090423B2 (enExample)
KR (1) KR101614976B1 (enExample)
CN (1) CN102245607B (enExample)
AU (1) AU2009304789B2 (enExample)
BR (1) BRPI0920199A2 (enExample)
CA (1) CA2740471C (enExample)
CO (1) CO6362009A2 (enExample)
DK (1) DK2336132T3 (enExample)
ES (1) ES2452541T3 (enExample)
IL (1) IL212278A (enExample)
MX (1) MX2011003490A (enExample)
MY (1) MY156456A (enExample)
NZ (1) NZ592761A (enExample)
PL (1) PL2336132T3 (enExample)
PT (1) PT2336132E (enExample)
RU (1) RU2490269C2 (enExample)
TW (1) TWI378933B (enExample)
WO (1) WO2010044401A1 (enExample)
ZA (1) ZA201102449B (enExample)

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CN102260263A (zh) * 2010-05-26 2011-11-30 四川大学 一类二苯胺基嘌呤衍生物及制备方法和医药用途
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CN108602825A (zh) * 2016-02-05 2018-09-28 中央研究院 具有抗癌活性的嘌呤化合物
US10722484B2 (en) 2016-03-09 2020-07-28 K-Gen, Inc. Methods of cancer treatment
CN110036109A (zh) 2016-12-02 2019-07-19 第一三共株式会社 新颖的内-β-N-乙酰基氨基葡糖苷酶
EP3360865A1 (en) 2017-02-13 2018-08-15 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of cyclopropyldiketopiperazines, and of a key intermediate of ds-5272
TWI837231B (zh) 2018-11-29 2024-04-01 日商第一三共股份有限公司 含有ｅｚｈ１／２雙重抑制劑之醫藥組合及其用途
CN113368114B (zh) * 2020-03-10 2022-04-22 四川大学 一种吗啉嘧啶类化合物的抗肿瘤应用
JP2024511996A (ja) * 2021-03-17 2024-03-18 タンゴ セラピューティクス， インコーポレイテッド 抗がん剤としてのプリン誘導体

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Also Published As

Publication number Publication date
EP2336132A4 (en) 2012-03-21
PT2336132E (pt) 2014-04-02
WO2010044401A1 (ja) 2010-04-22
RU2011119525A (ru) 2012-11-27
ES2452541T3 (es) 2014-04-01
NZ592761A (en) 2012-05-25
CN102245607A (zh) 2011-11-16
CO6362009A2 (es) 2012-01-20
JP2011001339A (ja) 2011-01-06
AU2009304789A1 (en) 2010-04-22
US8097622B2 (en) 2012-01-17
ZA201102449B (en) 2011-12-28
PL2336132T3 (pl) 2014-06-30
CA2740471C (en) 2013-09-17
US8309546B2 (en) 2012-11-13
EP2336132B1 (en) 2014-01-01
TW201018690A (en) 2010-05-16
IL212278A0 (en) 2011-06-30
BRPI0920199A2 (pt) 2019-09-24
MX2011003490A (es) 2011-04-21
MY156456A (en) 2016-02-26
CN102245607B (zh) 2014-07-02
CA2740471A1 (en) 2010-04-22
TWI378933B (en) 2012-12-11
HK1158189A1 (en) 2012-07-13
IL212278A (en) 2016-07-31
KR20110067038A (ko) 2011-06-20
EP2336132A1 (en) 2011-06-22
KR101614976B1 (ko) 2016-04-22
RU2490269C2 (ru) 2013-08-20
US20100130492A1 (en) 2010-05-27
JP5090423B2 (ja) 2012-12-05
AU2009304789B2 (en) 2012-04-05
US20120071476A1 (en) 2012-03-22

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