DK2201012T3 - Pyrrolo[2,3-d]pyrimidinderivater som proteinkinase b-hæmmere - Google Patents
Pyrrolo[2,3-d]pyrimidinderivater som proteinkinase b-hæmmereInfo
- Publication number
- DK2201012T3 DK2201012T3 DK08806741.8T DK08806741T DK2201012T3 DK 2201012 T3 DK2201012 T3 DK 2201012T3 DK 08806741 T DK08806741 T DK 08806741T DK 2201012 T3 DK2201012 T3 DK 2201012T3
- Authority
- DK
- Denmark
- Prior art keywords
- proteinkinase
- pyrrolo
- inhibitors
- pyrimidine derivatives
- pyrimidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97919207P | 2007-10-11 | 2007-10-11 | |
US4786208P | 2008-04-25 | 2008-04-25 | |
PCT/GB2008/050925 WO2009047563A1 (en) | 2007-10-11 | 2008-10-09 | Pyrrolo [2, 3 -d] pyrimidin derivatives as protein kinase b inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2201012T3 true DK2201012T3 (da) | 2014-09-08 |
Family
ID=40251789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08806741.8T DK2201012T3 (da) | 2007-10-11 | 2008-10-09 | Pyrrolo[2,3-d]pyrimidinderivater som proteinkinase b-hæmmere |
Country Status (38)
Country | Link |
---|---|
US (8) | US8101623B2 (da) |
EP (1) | EP2201012B1 (da) |
JP (2) | JP4705695B2 (da) |
KR (1) | KR101494734B1 (da) |
CN (1) | CN101861321B (da) |
AR (1) | AR068846A1 (da) |
AU (1) | AU2008309383B2 (da) |
BR (1) | BRPI0818533B8 (da) |
CA (1) | CA2701057C (da) |
CL (1) | CL2008003023A1 (da) |
CO (1) | CO6270328A2 (da) |
CR (1) | CR11359A (da) |
CU (1) | CU23886B1 (da) |
CY (1) | CY1116929T1 (da) |
DK (1) | DK2201012T3 (da) |
DO (1) | DOP2010000103A (da) |
EA (1) | EA018512B1 (da) |
ES (1) | ES2522365T3 (da) |
GT (1) | GT201000082A (da) |
HK (1) | HK1143154A1 (da) |
HN (1) | HN2010000653A (da) |
HR (1) | HRP20140807T1 (da) |
IL (1) | IL204721A (da) |
ME (1) | ME01999B (da) |
MX (1) | MX2010003927A (da) |
MY (1) | MY150059A (da) |
NI (1) | NI201000050A (da) |
NZ (1) | NZ585261A (da) |
PE (2) | PE20090964A1 (da) |
PL (1) | PL2201012T3 (da) |
PT (1) | PT2201012E (da) |
RS (1) | RS53552B1 (da) |
SA (1) | SA08290625B1 (da) |
SI (1) | SI2201012T1 (da) |
TW (1) | TWI453021B (da) |
UY (1) | UY31384A1 (da) |
WO (1) | WO2009047563A1 (da) |
ZA (1) | ZA201002318B (da) |
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US9670210B2 (en) | 2014-02-13 | 2017-06-06 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
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MY173661A (en) * | 2014-05-28 | 2020-02-14 | Astrazeneca Ab | Processes for the preparation of azd5363 and novel intermediate used therein |
TWI687419B (zh) | 2014-07-10 | 2020-03-11 | 美商英塞特公司 | 作為lsd1抑制劑之咪唑并吡啶及咪唑并吡嗪 |
US9695180B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors |
US9758523B2 (en) | 2014-07-10 | 2017-09-12 | Incyte Corporation | Triazolopyridines and triazolopyrazines as LSD1 inhibitors |
WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
CN107660205B (zh) | 2015-04-03 | 2021-08-27 | 因赛特公司 | 作为lsd1抑制剂的杂环化合物 |
EP3334709A1 (en) | 2015-08-12 | 2018-06-20 | Incyte Corporation | Salts of an lsd1 inhibitor |
TW201726140A (zh) | 2015-09-17 | 2017-08-01 | 瑞典商阿斯特捷利康公司 | 治療癌症之新型生物標記及方法 |
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2008
- 2008-10-09 TW TW097139021A patent/TWI453021B/zh active
- 2008-10-09 MX MX2010003927A patent/MX2010003927A/es active IP Right Grant
- 2008-10-09 EA EA201000552A patent/EA018512B1/ru not_active IP Right Cessation
- 2008-10-09 KR KR1020107010107A patent/KR101494734B1/ko active IP Right Grant
- 2008-10-09 PT PT88067418T patent/PT2201012E/pt unknown
- 2008-10-09 BR BRPI0818533A patent/BRPI0818533B8/pt active IP Right Grant
- 2008-10-09 ES ES08806741.8T patent/ES2522365T3/es active Active
- 2008-10-09 MY MYPI2010001617A patent/MY150059A/en unknown
- 2008-10-09 DK DK08806741.8T patent/DK2201012T3/da active
- 2008-10-09 AU AU2008309383A patent/AU2008309383B2/en active Active
- 2008-10-09 WO PCT/GB2008/050925 patent/WO2009047563A1/en active Application Filing
- 2008-10-09 CA CA2701057A patent/CA2701057C/en active Active
- 2008-10-09 PL PL08806741T patent/PL2201012T3/pl unknown
- 2008-10-09 NZ NZ585261A patent/NZ585261A/en unknown
- 2008-10-09 JP JP2010528485A patent/JP4705695B2/ja active Active
- 2008-10-09 ME MEP-2014-102A patent/ME01999B/me unknown
- 2008-10-09 CN CN200880116651XA patent/CN101861321B/zh active Active
- 2008-10-09 EP EP08806741.8A patent/EP2201012B1/en active Active
- 2008-10-09 UY UY31384A patent/UY31384A1/es not_active Application Discontinuation
- 2008-10-09 RS RS20140457A patent/RS53552B1/en unknown
- 2008-10-09 SI SI200831281T patent/SI2201012T1/sl unknown
- 2008-10-10 PE PE2008001748A patent/PE20090964A1/es active IP Right Grant
- 2008-10-10 PE PE2012002041A patent/PE20130152A1/es not_active Application Discontinuation
- 2008-10-10 AR ARP080104450A patent/AR068846A1/es active IP Right Grant
- 2008-10-10 US US12/249,477 patent/US8101623B2/en active Active
- 2008-10-10 CL CL2008003023A patent/CL2008003023A1/es unknown
- 2008-10-11 SA SA8290625A patent/SA08290625B1/ar unknown
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2010
- 2010-03-25 IL IL204721A patent/IL204721A/en active IP Right Grant
- 2010-03-31 ZA ZA2010/02318A patent/ZA201002318B/en unknown
- 2010-04-09 CU CU20100062A patent/CU23886B1/es active IP Right Grant
- 2010-04-09 NI NI201000050A patent/NI201000050A/es unknown
- 2010-04-09 DO DO2010000103A patent/DOP2010000103A/es unknown
- 2010-04-09 GT GT201000082A patent/GT201000082A/es unknown
- 2010-04-09 CR CR11359A patent/CR11359A/es unknown
- 2010-04-09 HN HN2010000653A patent/HN2010000653A/es unknown
- 2010-05-06 CO CO10054272A patent/CO6270328A2/es active IP Right Grant
- 2010-10-12 HK HK10109649.4A patent/HK1143154A1/xx unknown
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2011
- 2011-03-09 JP JP2011051117A patent/JP5330430B2/ja active Active
- 2011-12-13 US US13/324,191 patent/US20120190679A1/en not_active Abandoned
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2014
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- 2014-08-28 CY CY20141100689T patent/CY1116929T1/el unknown
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2015
- 2015-02-19 US US14/626,303 patent/US9492453B2/en active Active
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2016
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2018
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2020
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2021
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2023
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