DK2097400T3 - Kondenseret, substitueret aminopyrrolidinderivat - Google Patents

Kondenseret, substitueret aminopyrrolidinderivat

Info

Publication number
DK2097400T3
DK2097400T3 DK07860629.0T DK07860629T DK2097400T3 DK 2097400 T3 DK2097400 T3 DK 2097400T3 DK 07860629 T DK07860629 T DK 07860629T DK 2097400 T3 DK2097400 T3 DK 2097400T3
Authority
DK
Denmark
Prior art keywords
condensed
aminopyrrolidine derivative
substituted aminopyrrolidine
substituted
derivative
Prior art date
Application number
DK07860629.0T
Other languages
Danish (da)
English (en)
Inventor
Hisashi Takahashi
Satoshi Komoriya
Takahiro Kitamura
Takashi Odagiri
Hiroaki Inagaki
Toshifumi Tsuda
Kiyoshi Nakayama
Makoto Takemura
Kenichi Yoshida
Rie Miyauchi
Masatoshi Nagamochi
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of DK2097400T3 publication Critical patent/DK2097400T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK07860629.0T 2007-01-05 2007-12-28 Kondenseret, substitueret aminopyrrolidinderivat DK2097400T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007000667 2007-01-05
JP2007074991 2007-03-22
PCT/JP2007/075434 WO2008082009A2 (en) 2007-01-05 2007-12-28 Fused substituted aminopyrrolidine derivative

Publications (1)

Publication Number Publication Date
DK2097400T3 true DK2097400T3 (da) 2013-10-14

Family

ID=39522355

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07860629.0T DK2097400T3 (da) 2007-01-05 2007-12-28 Kondenseret, substitueret aminopyrrolidinderivat

Country Status (24)

Country Link
US (2) US8618094B2 (enExample)
EP (2) EP2540715A1 (enExample)
JP (1) JP5197606B2 (enExample)
KR (1) KR101419085B1 (enExample)
AR (1) AR064753A1 (enExample)
AU (1) AU2007339692B2 (enExample)
BR (1) BRPI0720771A2 (enExample)
CA (1) CA2674369C (enExample)
CL (1) CL2008000026A1 (enExample)
CY (1) CY1114444T1 (enExample)
DK (1) DK2097400T3 (enExample)
ES (1) ES2428344T3 (enExample)
IL (1) IL199694A (enExample)
MX (1) MX2009007291A (enExample)
MY (1) MY162052A (enExample)
NO (1) NO20092804L (enExample)
NZ (1) NZ577214A (enExample)
PE (1) PE20081631A1 (enExample)
PL (1) PL2097400T3 (enExample)
PT (1) PT2097400E (enExample)
RU (1) RU2443698C2 (enExample)
SI (1) SI2097400T1 (enExample)
TW (1) TWI409068B (enExample)
WO (1) WO2008082009A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2012018105A1 (ja) * 2010-08-06 2013-10-03 第一三共株式会社 抗菌化合物の結晶
WO2014152317A2 (en) * 2013-03-15 2014-09-25 Melinta Therapeutics, Inc. Methods of treating gonorrhea infections using quinolone antibiotics
SG11201806416XA (en) 2016-02-12 2018-08-30 Astellas Pharma Inc Tetrahydroisoquinoline derivatives
PH12022550774A1 (en) * 2019-10-23 2023-05-03 Taigen Biotechnology Co Ltd Quinolone carboxylic acid derivatives
CA3227204A1 (en) * 2021-07-22 2023-01-26 The Texas A&M University System Activated ferrate solutions and methods thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61282382A (ja) 1985-06-06 1986-12-12 Dainippon Pharmaceut Co Ltd フエニル置換１，８−ナフチリジン誘導体、そのエステルおよびその塩
EP0242789A3 (en) 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof
JPH0676400B2 (ja) * 1987-08-25 1994-09-28 大日本製薬株式会社 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
IL90062A (en) 1988-04-27 1994-10-07 Daiichi Seiyaku Co Pyridonecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
JP2807277B2 (ja) 1988-08-31 1998-10-08 第一製薬株式会社 スピロ化合物
JPH0278659A (ja) * 1988-09-12 1990-03-19 Shionogi & Co Ltd アザビシクロアルカン類化合物
EP0677522A4 (en) 1992-12-28 1995-12-27 Yoshitomi Pharmaceutical 8-methoxyquinolonecarboxylic acid derivative.
JPH06345261A (ja) 1993-04-16 1994-12-20 Daihen Corp 自動搬送装置の搬送用ハンド
PT812838E (pt) * 1994-02-04 2002-10-31 Dainippon Pharmaceutical Co Derivado de acido piridonacarboxilico substituido com o grupo amino biciclico seu ester seu sal e amina biciclica como seu intermediario
DE4435479A1 (de) 1994-10-04 1996-04-11 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
PT807630E (pt) * 1995-02-02 2003-08-29 Daiichi Seiyaku Co Compostos heterociclicos
KR19990022524A (ko) * 1995-06-06 1999-03-25 웨인스톡 스티븐 에프. 퀴놀리지논형화합물
JP4132155B2 (ja) * 1996-10-25 2008-08-13 第一三共株式会社 三環性アミン誘導体
ATE297912T1 (de) * 1998-11-24 2005-07-15 Daiichi Seiyaku Co Cycloalkylsubstituierte aminomethylpyrrolidin- derivate
EP1336612B1 (en) * 2000-11-24 2007-01-17 Meiji Seika Kaisha Ltd. Novel carbapenem derivatives
WO2005049602A1 (en) * 2003-11-18 2005-06-02 Warner-Lambert Company Llc Quinolone antibacterial agents
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative

Also Published As

Publication number Publication date
CA2674369A1 (en) 2008-07-10
WO2008082009A3 (en) 2008-12-11
WO2008082009A2 (en) 2008-07-10
JP2010515663A (ja) 2010-05-13
EP2097400A2 (en) 2009-09-09
JP5197606B2 (ja) 2013-05-15
PE20081631A1 (es) 2008-11-22
AU2007339692A1 (en) 2008-07-10
IL199694A (en) 2013-08-29
CA2674369C (en) 2012-04-03
US8618094B2 (en) 2013-12-31
TWI409068B (zh) 2013-09-21
NO20092804L (no) 2009-10-05
US20130029977A9 (en) 2013-01-31
EP2540715A1 (en) 2013-01-02
PT2097400E (pt) 2013-10-10
RU2009129975A (ru) 2011-02-10
HK1130056A1 (en) 2009-12-18
SI2097400T1 (sl) 2013-10-30
MY162052A (en) 2017-05-31
AR064753A1 (es) 2009-04-22
IL199694A0 (en) 2010-04-15
BRPI0720771A2 (pt) 2014-07-15
RU2443698C2 (ru) 2012-02-27
TW200836733A (en) 2008-09-16
NZ577214A (en) 2011-11-25
KR20090096618A (ko) 2009-09-11
CY1114444T1 (el) 2016-08-31
EP2097400B1 (en) 2013-07-03
MX2009007291A (es) 2009-07-14
PL2097400T3 (pl) 2013-11-29
KR101419085B1 (ko) 2014-07-15
AU2007339692B2 (en) 2012-01-19
US20120108582A1 (en) 2012-05-03
ES2428344T3 (es) 2013-11-07
CL2008000026A1 (es) 2008-05-16
US20140142096A1 (en) 2014-05-22

Similar Documents

Publication Publication Date Title
FR24C1047I2 (fr) Derive de 4-pyrimidinesulfamide
HRP20151058T1 (xx) Ariloazol-2-il-cijanoetilamino-spojevi, postupak njihove proizvodnje i postupak njihove uporabe
NO2021006I1 (no) Quofenix, delafloksacin
NL2000581A1 (nl) Aangecondenseerde fenylamidoheterocyclische verbindingen.
EP2226315A4 (en) 2-aminoquinazoline DERIVATIVE
BRPI0815717A2 (pt) Compostos de imidazopirazina.
DK2041123T3 (da) Kondenserede cykliske forbindelser.
BRPI0923786A2 (pt) compostos 5,6-dihidro-6-fenilbenzo(f) isoquinolina-2- amina substituidos
ATE555107T1 (de) 2-aza-bicyclo-ä2,2,1-üheptan-derivate
EP2170350A4 (en) SUBSTITUTED IMIDAZOHETEROCYCLES
ATE542825T1 (de) Substituierte piperidino-dihydrothienopyrimidine
EP2233474A4 (en) CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE
BRPI0813235A2 (pt) Combinação anti-helmíntica.
EP2344471A4 (en) 7-PIPERIDINALKYL-3,4-dihydroquinolone DERIVATIVE
CL2007002263S1 (es) Motoneta.
ATE502012T1 (de) 1,1,1-trifluor-2-hydroxy-3-phenylpropan-derivat
BRPI0816970A2 (pt) 1,3-dissubstituídas-4-fenil-1h-piridin-2-onas
CL2008000457S1 (es) Motoneta.
CL2007003097S1 (es) Motocicleta.
ATE527260T1 (de) (dihydro)pyrroloä2,1-aüisoquinoline
BRPI0815059A2 (pt) Derivado de 1,3-di-hidroisoindol
BRPI0917446A2 (pt) derivados de acilaminobenzamida.
BRPI0906714A2 (pt) Derivados de oxazepinopirimidona heteroarilamida substituídos.
BRPI0814748A2 (pt) Compostos de alditóis substituídos, composições e métodos
BRPI0816679A2 (pt) Derivados de ftalazinona.