DK2012789T3 - Fremgangsmåde til behandling af aldersrelateret makulær degeneration (AMD) - Google Patents
Fremgangsmåde til behandling af aldersrelateret makulær degeneration (AMD)Info
- Publication number
- DK2012789T3 DK2012789T3 DK07718737.5T DK07718737T DK2012789T3 DK 2012789 T3 DK2012789 T3 DK 2012789T3 DK 07718737 T DK07718737 T DK 07718737T DK 2012789 T3 DK2012789 T3 DK 2012789T3
- Authority
- DK
- Denmark
- Prior art keywords
- amd
- age
- macular degeneration
- related macular
- degeneration
- Prior art date
Links
- 206010064930 age-related macular degeneration Diseases 0.000 title 2
- 208000002780 macular degeneration Diseases 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79227806P | 2006-04-14 | 2006-04-14 | |
| PCT/AU2007/000490 WO2007118276A1 (en) | 2006-04-14 | 2007-04-13 | Method of treatment of age-related macular degeneration(amd) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2012789T3 true DK2012789T3 (da) | 2013-12-16 |
Family
ID=38608967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07718737.5T DK2012789T3 (da) | 2006-04-14 | 2007-04-13 | Fremgangsmåde til behandling af aldersrelateret makulær degeneration (AMD) |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20100144693A1 (enExample) |
| EP (2) | EP2514423A3 (enExample) |
| JP (1) | JP5290147B2 (enExample) |
| KR (2) | KR20100110396A (enExample) |
| CN (3) | CN101987849B (enExample) |
| AU (2) | AU2007240120A1 (enExample) |
| BR (2) | BRPI0722382A2 (enExample) |
| CA (1) | CA2683756A1 (enExample) |
| DK (1) | DK2012789T3 (enExample) |
| ES (1) | ES2437997T3 (enExample) |
| IL (1) | IL207495A (enExample) |
| NZ (2) | NZ590271A (enExample) |
| WO (1) | WO2007118276A1 (enExample) |
| ZA (2) | ZA200809493B (enExample) |
Families Citing this family (30)
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| AU2002950217A0 (en) | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
| AU2006249866B2 (en) | 2005-05-26 | 2011-10-13 | Aldeyra Therapeutics, Inc. | Compositions and methods of treating retinal disease |
| JP5415942B2 (ja) * | 2006-06-22 | 2014-02-12 | プラナ バイオテクノロジー リミティッド | 処置の方法およびその処置に有用な薬剤 |
| CA2737219C (en) * | 2008-08-11 | 2017-02-28 | Tracy Keller | Halofuginone analogs for inhibition of trna synthetases and uses thereof |
| WO2010071944A1 (en) * | 2008-12-24 | 2010-07-01 | Prana Biotechnology Limited | Quinazolinone compounds |
| EP2389179A4 (en) | 2009-01-26 | 2012-08-29 | Michael Spino | USE OF DEFERPRONE FOR THE TREATMENT AND PREVENTION OF IRON-RELATED EYE DISORDERS |
| CA2782015C (en) | 2009-12-11 | 2020-08-25 | Neuron Systems, Inc. | Topical ophthalmic compositions and methods for the treatment of macular degeneration |
| WO2012122534A2 (en) | 2011-03-10 | 2012-09-13 | The Trustees Of Columbia University In The City Of New York | N-quinolin-benzensulfonamides and related compounds for the treatment of cancer, autoimmune disorders and inflammation |
| CA2861840C (en) | 2012-01-13 | 2020-12-15 | President And Fellows Of Harvard College | Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions |
| KR20150118106A (ko) | 2012-12-20 | 2015-10-21 | 알데이라 테라퓨틱스, 아이엔씨. | 페리-카르비놀 |
| CN111135171B (zh) | 2013-01-23 | 2023-09-08 | 奥尔德拉医疗公司 | 与毒性醛相关的疾病和治疗 |
| AU2014209585A1 (en) | 2013-01-25 | 2015-07-23 | Aldeyra Therapeutics, Inc. | Novel traps in the treatment of macular degeneration |
| EA031505B1 (ru) * | 2014-12-02 | 2019-01-31 | Прана Байотекнолоджи Лимитед | СОЕДИНЕНИЯ 4Н-ПИРИДО[1,2-а]ПИРИМИДИН-4-ОНА |
| CN107533181B (zh) * | 2015-04-29 | 2020-06-30 | 特里亚佩克斯有限公司 | 偏光膜、制备它的方法及包含它的偏光镜片 |
| US10781178B2 (en) * | 2015-08-12 | 2020-09-22 | The General Hospital Corporation | 8-hydroxyquinoline derivatives as diagnostic and therapeutic agents |
| CN118724806A (zh) | 2015-08-21 | 2024-10-01 | 奥尔德拉医疗公司 | 氘化化合物和其用途 |
| US11008290B2 (en) * | 2015-09-24 | 2021-05-18 | University Of Florida Research Foundation, Incorporated | Halogenated quinoline derivatives as antimicrobial agents |
| CN109152774A (zh) | 2016-05-09 | 2019-01-04 | 奥尔德拉医疗公司 | 眼部炎性病症和疾病的组合治疗 |
| WO2018000047A1 (en) * | 2016-07-01 | 2018-01-04 | Prana Biotechnology Limited | Method of treating immunoglobulin light chain amyloidosis |
| WO2018170476A1 (en) | 2017-03-16 | 2018-09-20 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| CN111356451A (zh) | 2017-10-10 | 2020-06-30 | 奥尔德拉医疗公司 | 炎性病症的治疗 |
| WO2019237125A1 (en) | 2018-06-08 | 2019-12-12 | The General Hospital Corporation | Inhibitors of prolyl-trna-synthetase |
| CN112714762A (zh) | 2018-08-06 | 2021-04-27 | 奥尔德拉医疗公司 | 多晶型化合物及其用途 |
| CN109232396B (zh) * | 2018-11-27 | 2020-07-03 | 聊城大学 | 酰胺吡啶类衍生物及其用途 |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| CN113784954A (zh) | 2019-05-02 | 2021-12-10 | 奥尔德拉医疗公司 | 多晶型化合物和其用途 |
| WO2021231792A1 (en) | 2020-05-13 | 2021-11-18 | Aldeyra Therapeutics, Inc. | Pharmaceutical formulations and uses thereof |
| EP4175636A2 (en) * | 2020-07-02 | 2023-05-10 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Cyclic compounds for use in treating retinal degeneration |
| US12060334B2 (en) | 2021-03-12 | 2024-08-13 | University Of Florida Research Foundation, Incorporated | 3-substituted phenazine derivatives as antimicrobial agents |
| CN113214249B (zh) * | 2021-04-23 | 2023-09-19 | 成都大学 | 吡啶并[1,2-a]嘧啶-4-硫酮化合物的合成方法 |
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-
2007
- 2007-04-13 BR BRPI0722382-0A patent/BRPI0722382A2/pt not_active Application Discontinuation
- 2007-04-13 NZ NZ590271A patent/NZ590271A/en unknown
- 2007-04-13 US US12/297,165 patent/US20100144693A1/en not_active Abandoned
- 2007-04-13 KR KR1020107020805A patent/KR20100110396A/ko not_active Ceased
- 2007-04-13 AU AU2007240120A patent/AU2007240120A1/en not_active Abandoned
- 2007-04-13 BR BRPI0710737-4A patent/BRPI0710737A2/pt not_active IP Right Cessation
- 2007-04-13 CA CA002683756A patent/CA2683756A1/en not_active Abandoned
- 2007-04-13 ES ES07718737.5T patent/ES2437997T3/es active Active
- 2007-04-13 CN CN2010102559981A patent/CN101987849B/zh not_active Expired - Fee Related
- 2007-04-13 JP JP2009504530A patent/JP5290147B2/ja not_active Expired - Fee Related
- 2007-04-13 CN CN2011101585377A patent/CN102225930A/zh active Pending
- 2007-04-13 CN CNA2007800222734A patent/CN101534826A/zh active Pending
- 2007-04-13 DK DK07718737.5T patent/DK2012789T3/da active
- 2007-04-13 WO PCT/AU2007/000490 patent/WO2007118276A1/en not_active Ceased
- 2007-04-13 NZ NZ572591A patent/NZ572591A/en not_active IP Right Cessation
- 2007-04-13 EP EP12176495A patent/EP2514423A3/en not_active Withdrawn
- 2007-04-13 EP EP07718737.5A patent/EP2012789B1/en not_active Not-in-force
- 2007-04-13 KR KR1020087027935A patent/KR20080109096A/ko not_active Ceased
- 2007-04-13 ZA ZA200809493A patent/ZA200809493B/xx unknown
-
2010
- 2010-07-30 AU AU2010206074A patent/AU2010206074B2/en not_active Ceased
- 2010-08-09 IL IL207495A patent/IL207495A/en active IP Right Grant
- 2010-08-19 ZA ZA2010/05922A patent/ZA201005922B/en unknown
- 2010-11-23 US US12/952,425 patent/US20110071167A1/en not_active Abandoned
-
2013
- 2013-11-22 US US14/087,689 patent/US9163018B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007240120A2 (en) | 2008-12-18 |
| IL207495A (en) | 2015-05-31 |
| AU2010206074A1 (en) | 2010-08-19 |
| IL207495A0 (en) | 2010-12-30 |
| ZA201005922B (en) | 2013-09-25 |
| WO2007118276A1 (en) | 2007-10-25 |
| EP2514423A3 (en) | 2012-12-19 |
| AU2010206074B2 (en) | 2012-08-30 |
| NZ572591A (en) | 2012-01-12 |
| ES2437997T3 (es) | 2014-01-15 |
| US20140088122A1 (en) | 2014-03-27 |
| NZ590271A (en) | 2011-12-22 |
| EP2012789B1 (en) | 2013-09-25 |
| AU2007240120A1 (en) | 2007-10-25 |
| US20100144693A1 (en) | 2010-06-10 |
| JP2009533356A (ja) | 2009-09-17 |
| ZA200809493B (en) | 2010-08-25 |
| KR20080109096A (ko) | 2008-12-16 |
| US20110071167A1 (en) | 2011-03-24 |
| CA2683756A1 (en) | 2007-10-25 |
| EP2514423A2 (en) | 2012-10-24 |
| EP2012789A4 (en) | 2011-02-16 |
| EP2012789A1 (en) | 2009-01-14 |
| US9163018B2 (en) | 2015-10-20 |
| CN102225930A (zh) | 2011-10-26 |
| BRPI0722382A2 (pt) | 2012-06-05 |
| KR20100110396A (ko) | 2010-10-12 |
| CN101987849B (zh) | 2013-05-08 |
| CN101534826A (zh) | 2009-09-16 |
| CN101987849A (zh) | 2011-03-23 |
| JP5290147B2 (ja) | 2013-09-18 |
| BRPI0710737A2 (pt) | 2011-05-10 |
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