DK2029567T3 - Fremgangsmåde til frembringelse af benzopyran-2-ol-derivater - Google Patents
Fremgangsmåde til frembringelse af benzopyran-2-ol-derivaterInfo
- Publication number
- DK2029567T3 DK2029567T3 DK07734680.7T DK07734680T DK2029567T3 DK 2029567 T3 DK2029567 T3 DK 2029567T3 DK 07734680 T DK07734680 T DK 07734680T DK 2029567 T3 DK2029567 T3 DK 2029567T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- benzopyran
- producing
- producing benzopyran
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80306806P | 2006-05-24 | 2006-05-24 | |
| PCT/IB2007/001379 WO2007138440A1 (en) | 2006-05-24 | 2007-05-21 | Process for the production of benzopyran-2-ol derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2029567T3 true DK2029567T3 (da) | 2010-11-29 |
Family
ID=37232871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07734680.7T DK2029567T3 (da) | 2006-05-24 | 2007-05-21 | Fremgangsmåde til frembringelse af benzopyran-2-ol-derivater |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8067594B2 (da) |
| EP (1) | EP2029567B1 (da) |
| JP (1) | JP5269349B2 (da) |
| KR (1) | KR101087326B1 (da) |
| CN (1) | CN101454304B (da) |
| AR (1) | AR061112A1 (da) |
| AT (1) | ATE480531T1 (da) |
| AU (1) | AU2007266761B2 (da) |
| BR (1) | BRPI0712037A2 (da) |
| CA (1) | CA2651978C (da) |
| CY (1) | CY1110823T1 (da) |
| DE (1) | DE602007009096D1 (da) |
| DK (1) | DK2029567T3 (da) |
| ES (1) | ES2350056T3 (da) |
| HK (1) | HK1133425A1 (da) |
| IL (2) | IL194959A0 (da) |
| MX (1) | MX2008012976A (da) |
| NZ (1) | NZ571988A (da) |
| PL (1) | PL2029567T3 (da) |
| PT (1) | PT2029567E (da) |
| RU (1) | RU2397163C2 (da) |
| SG (1) | SG158070A1 (da) |
| TW (1) | TWI343381B (da) |
| WO (1) | WO2007138440A1 (da) |
| ZA (1) | ZA200808527B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2027103T3 (da) * | 2006-06-12 | 2014-04-22 | Ucb Pharma Gmbh | Nyt chiralt mellemprodukt, fremgangsmåde til fremstilling deraf og dets anvendelse i fremstillingen af tolterodin, fesoterodin, eller den aktive metabolit deraf |
| BRPI1010820A2 (pt) | 2009-05-11 | 2019-09-24 | Ratiopharm Gmbh | desfesoterodina na forma de um sal de acido tartarico |
| ES2456866T3 (es) | 2009-07-27 | 2014-04-23 | Crystal Pharma, S.A.U. | Procedimiento para la obtención de 3,3-difenilpropilaminas |
| IT1396373B1 (it) * | 2009-10-29 | 2012-11-19 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina. |
| EP2364966A1 (en) | 2010-03-09 | 2011-09-14 | LEK Pharmaceuticals d.d. | Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-3-phenylpropylamines, intermediates for making hydroxytolterodine |
| IT1401451B1 (it) * | 2010-06-10 | 2013-07-26 | Chemi Spa | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
| WO2011158257A1 (en) | 2010-06-18 | 2011-12-22 | Panacea Biotec Ltd | Preparation process of fesoterodine and intermediates |
| CN102329244A (zh) * | 2010-07-13 | 2012-01-25 | 凯瑞斯德生化(苏州)有限公司 | 一种rs-托特罗定的制备方法及中间体化合物 |
| WO2012025941A2 (en) | 2010-08-25 | 2012-03-01 | Cadila Healthcare Limited | Processes for the preparation of fesoterodine |
| IT1403094B1 (it) | 2010-12-09 | 2013-10-04 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina o un suo sale |
| WO2013113946A2 (en) | 2012-05-04 | 2013-08-08 | Crystal Pharma, S.A.U. | Process for the preparation of optically active 3,3-diphenylpropylamines |
| PL2760822T3 (pl) | 2012-06-14 | 2016-09-30 | Sole desfezoterodyny | |
| ITMI20121232A1 (it) | 2012-07-16 | 2014-01-17 | Cambrex Profarmaco Milano Srl | Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati |
| CN103044273B (zh) * | 2012-11-29 | 2014-12-24 | 珠海保税区丽珠合成制药有限公司 | 一种酒石酸托特罗定的合成方法 |
| WO2017137955A1 (en) | 2016-02-14 | 2017-08-17 | Celestis Pharmaceuticals Pvt. Ltd. | Novel (r) and rac 3-(2-(allyloxy)-5-methylphenyl)-n,n-diisopropyl-3- phenylpropan-1-amine and its use for synthesis of (r) and rac-2-(3- (diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol |
| RU2652119C1 (ru) * | 2016-12-14 | 2018-04-25 | федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный технический университет" | Способ получения производных хроман-2-аминов |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19525137C2 (de) * | 1995-07-11 | 2003-02-27 | Gruenenthal Gmbh | 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe |
| KR20000057548A (ko) * | 1996-12-13 | 2000-09-25 | 알프레드 엘. 미첼슨 | 광학적 전송물질 및 결합재 |
| EP0957073A1 (en) | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| DE29923134U1 (de) * | 1999-11-16 | 2000-06-29 | Sanol Arznei Schwarz Gmbh | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
| SE9904850D0 (sv) | 1999-12-30 | 1999-12-30 | Pharmacia & Upjohn Ab | Novel process and intermediates |
| DE10033016A1 (de) * | 2000-07-07 | 2002-01-24 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen |
| US7173139B2 (en) | 2001-06-29 | 2007-02-06 | California Institute Of Technology | Enantioselective 1,4-addition of aromatic nucleophiles to α,β-unsaturated aldehydes using chiral organic catalysts |
| MXPA05011225A (es) * | 2003-04-18 | 2005-12-14 | Pharmacia & Upjohn Co Llc | Politerapias. |
-
2007
- 2007-05-21 MX MX2008012976A patent/MX2008012976A/es active IP Right Grant
- 2007-05-21 AT AT07734680T patent/ATE480531T1/de active
- 2007-05-21 DE DE602007009096T patent/DE602007009096D1/de active Active
- 2007-05-21 BR BRPI0712037-0A patent/BRPI0712037A2/pt not_active Application Discontinuation
- 2007-05-21 SG SG200907701-7A patent/SG158070A1/en unknown
- 2007-05-21 EP EP07734680A patent/EP2029567B1/en active Active
- 2007-05-21 RU RU2008141413/04A patent/RU2397163C2/ru active
- 2007-05-21 AU AU2007266761A patent/AU2007266761B2/en not_active Ceased
- 2007-05-21 ES ES07734680T patent/ES2350056T3/es active Active
- 2007-05-21 NZ NZ571988A patent/NZ571988A/en not_active IP Right Cessation
- 2007-05-21 PT PT07734680T patent/PT2029567E/pt unknown
- 2007-05-21 KR KR1020087028577A patent/KR101087326B1/ko not_active IP Right Cessation
- 2007-05-21 US US12/302,228 patent/US8067594B2/en active Active
- 2007-05-21 CN CN2007800191401A patent/CN101454304B/zh active Active
- 2007-05-21 CA CA2651978A patent/CA2651978C/en not_active Expired - Fee Related
- 2007-05-21 DK DK07734680.7T patent/DK2029567T3/da active
- 2007-05-21 PL PL07734680T patent/PL2029567T3/pl unknown
- 2007-05-21 WO PCT/IB2007/001379 patent/WO2007138440A1/en active Application Filing
- 2007-05-22 JP JP2007135615A patent/JP5269349B2/ja active Active
- 2007-05-23 TW TW096118354A patent/TWI343381B/zh not_active IP Right Cessation
- 2007-05-23 AR ARP070102234A patent/AR061112A1/es not_active Application Discontinuation
-
2008
- 2008-10-07 ZA ZA200808527A patent/ZA200808527B/xx unknown
- 2008-10-28 IL IL194959A patent/IL194959A0/en unknown
-
2009
- 2009-12-01 HK HK09111229.1A patent/HK1133425A1/xx not_active IP Right Cessation
-
2010
- 2010-10-11 CY CY20101100903T patent/CY1110823T1/el unknown
-
2012
- 2012-06-14 IL IL220430A patent/IL220430A0/en unknown
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