DK2160225T3 - Fremgangsmåde til fremstilling af krystaller - Google Patents

Fremgangsmåde til fremstilling af krystaller

Info

Publication number
DK2160225T3
DK2160225T3 DK08762562.0T DK08762562T DK2160225T3 DK 2160225 T3 DK2160225 T3 DK 2160225T3 DK 08762562 T DK08762562 T DK 08762562T DK 2160225 T3 DK2160225 T3 DK 2160225T3
Authority
DK
Denmark
Prior art keywords
producing crystals
crystals
producing
Prior art date
Application number
DK08762562.0T
Other languages
English (en)
Inventor
Graham Ruecroft
James Robinson
Dipesh Parikh
Original Assignee
Prosonix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prosonix Ltd filed Critical Prosonix Ltd
Application granted granted Critical
Publication of DK2160225T3 publication Critical patent/DK2160225T3/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0004—Crystallisation cooling by heat exchange
    • B01D9/0009—Crystallisation cooling by heat exchange by direct heat exchange with added cooling fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0018—Evaporation of components of the mixture to be separated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B01D9/0054—Use of anti-solvent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0059—General arrangements of crystallisation plant, e.g. flow sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0081—Use of vibrations, e.g. ultrasound
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/02—Crystallisation from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/10—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing sonic or ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/18—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
DK08762562.0T 2007-06-18 2008-06-17 Fremgangsmåde til fremstilling af krystaller DK2160225T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0711680.9A GB0711680D0 (en) 2007-06-18 2007-06-18 Process
PCT/GB2008/050452 WO2008155570A1 (en) 2007-06-18 2008-06-17 Process for making crystals

Publications (1)

Publication Number Publication Date
DK2160225T3 true DK2160225T3 (da) 2013-09-02

Family

ID=38332229

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08762562.0T DK2160225T3 (da) 2007-06-18 2008-06-17 Fremgangsmåde til fremstilling af krystaller

Country Status (10)

Country Link
US (1) US9278323B2 (da)
EP (1) EP2160225B1 (da)
DK (1) DK2160225T3 (da)
ES (1) ES2429295T3 (da)
GB (2) GB0711680D0 (da)
HR (1) HRP20130786T1 (da)
IL (1) IL202643A (da)
PL (1) PL2160225T3 (da)
PT (1) PT2160225E (da)
WO (1) WO2008155570A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
EP2473247A2 (en) * 2009-09-01 2012-07-11 University Of Durham Method of controlling crystallisation
EP2360147A1 (en) 2010-02-22 2011-08-24 CHIESI FARMACEUTICI S.p.A. Process for preparing crystalline particles of a salt of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino] ethyl]-2(1H)-quinolinone (carmoterol)
CA2794941C (en) 2010-04-01 2018-05-15 Chiesi Farmaceutici S.P.A. Process for preparing carrier particles for dry powders for inhalation
CN102294192A (zh) * 2010-06-28 2011-12-28 北京翔奥天竺科技有限公司 超声波混合装置
EP2500072A1 (en) 2011-03-15 2012-09-19 LEK Pharmaceuticals d.d. A novel process of residual solvent removal
DK3517541T3 (da) 2012-05-08 2020-09-07 Nicox Ophthalmics Inc Polymorf form af fluticasonpropionat
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
CN104549021B (zh) * 2015-01-13 2015-12-30 中国石油大学(华东) 一种疏水纳米颗粒与表面活性剂复配分散体制备装置及应用
US10583085B2 (en) 2017-05-17 2020-03-10 Chiesi Farmaceutici S.P.A. Carrier particles for dry powder formulations for inhalation
TW201934483A (zh) * 2017-12-28 2019-09-01 奧地利商施華洛世奇股份有限公司 製造光子結晶的方法及裝置
MX2021000779A (es) 2018-07-27 2021-03-31 Chiesi Farm Spa Nuevas particulas portadoras para formulaciones de polvo seco para inhalacion.

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4023935A (en) * 1971-09-15 1977-05-17 Thiokol Corporation Method of making finely particulate ammonium perchlorate
US5874029A (en) * 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
SE9801287D0 (sv) 1998-04-14 1998-04-14 Astra Ab Incorporation of active substances in carrier matrixes
GB9810859D0 (en) * 1998-05-20 1998-07-22 Zeneca Ltd Crystallisation process
GB9826242D0 (en) 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9828721D0 (en) * 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
GB0015981D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0016002D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
CA2445146A1 (en) * 2001-05-05 2002-11-14 Accentus Plc Formation of small crystals
WO2003032951A1 (en) * 2001-08-29 2003-04-24 Dow Global Technologies Inc. A process for preparing crystalline drug particles by means of precipitation
GB0125604D0 (en) * 2001-10-25 2001-12-19 Glaxo Group Ltd Novel process
GB0201400D0 (en) 2002-01-22 2002-03-13 Glaxo Group Ltd Novel apparatus and process
US6998051B2 (en) 2002-07-03 2006-02-14 Ferro Corporation Particles from supercritical fluid extraction of emulsion
US20040197275A1 (en) * 2002-10-17 2004-10-07 Ecole Polytechnique Federale De Lausanne Process for the manufacture of powders of inhalable medicaments
WO2004073827A1 (en) * 2003-02-21 2004-09-02 The University Of Bath Process for the production of particles
AU2004234057A1 (en) * 2003-04-29 2004-11-11 Akzo Nobel N.V. Antisolvent solidification process
US7208106B2 (en) * 2003-10-24 2007-04-24 Ferro Corporation Method of forming particles
WO2005051511A1 (ja) * 2003-11-28 2005-06-09 Mitsubishi Chemical Corporation 有機化合物微粒子の製造方法

Also Published As

Publication number Publication date
PT2160225E (pt) 2013-09-13
US9278323B2 (en) 2016-03-08
PL2160225T3 (pl) 2014-01-31
US20100190760A1 (en) 2010-07-29
IL202643A0 (en) 2010-06-30
GB0711680D0 (en) 2007-07-25
HRP20130786T1 (en) 2013-10-11
EP2160225A1 (en) 2010-03-10
ES2429295T3 (es) 2013-11-14
IL202643A (en) 2013-08-29
WO2008155570A1 (en) 2008-12-24
GB2461028B (en) 2011-12-07
GB2461028A (en) 2009-12-23
EP2160225B1 (en) 2013-07-31
GB0811007D0 (en) 2008-07-23
GB2461028A8 (en) 2011-11-23
GB2461028C (en) 2015-07-15

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