PL2029567T3 - Sposób wytwarzania pochodnych benzopiran-2-olu - Google Patents

Sposób wytwarzania pochodnych benzopiran-2-olu

Info

Publication number
PL2029567T3
PL2029567T3 PL07734680T PL07734680T PL2029567T3 PL 2029567 T3 PL2029567 T3 PL 2029567T3 PL 07734680 T PL07734680 T PL 07734680T PL 07734680 T PL07734680 T PL 07734680T PL 2029567 T3 PL2029567 T3 PL 2029567T3
Authority
PL
Poland
Prior art keywords
benzopyran
derivatives
production
Prior art date
Application number
PL07734680T
Other languages
English (en)
Inventor
Jens Bertil Ahman
Barry Richard Dillon
Alan John Pettman
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of PL2029567T3 publication Critical patent/PL2029567T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
PL07734680T 2006-05-24 2007-05-21 Sposób wytwarzania pochodnych benzopiran-2-olu PL2029567T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80306806P 2006-05-24 2006-05-24
PCT/IB2007/001379 WO2007138440A1 (en) 2006-05-24 2007-05-21 Process for the production of benzopyran-2-ol derivatives
EP07734680A EP2029567B1 (en) 2006-05-24 2007-05-21 Process for the production of benzopyran-2-ol derivatives

Publications (1)

Publication Number Publication Date
PL2029567T3 true PL2029567T3 (pl) 2011-01-31

Family

ID=37232871

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07734680T PL2029567T3 (pl) 2006-05-24 2007-05-21 Sposób wytwarzania pochodnych benzopiran-2-olu

Country Status (25)

Country Link
US (1) US8067594B2 (pl)
EP (1) EP2029567B1 (pl)
JP (1) JP5269349B2 (pl)
KR (1) KR101087326B1 (pl)
CN (1) CN101454304B (pl)
AR (1) AR061112A1 (pl)
AT (1) ATE480531T1 (pl)
AU (1) AU2007266761B2 (pl)
BR (1) BRPI0712037A2 (pl)
CA (1) CA2651978C (pl)
CY (1) CY1110823T1 (pl)
DE (1) DE602007009096D1 (pl)
DK (1) DK2029567T3 (pl)
ES (1) ES2350056T3 (pl)
HK (1) HK1133425A1 (pl)
IL (2) IL194959A0 (pl)
MX (1) MX2008012976A (pl)
NZ (1) NZ571988A (pl)
PL (1) PL2029567T3 (pl)
PT (1) PT2029567E (pl)
RU (1) RU2397163C2 (pl)
SG (1) SG158070A1 (pl)
TW (1) TWI343381B (pl)
WO (1) WO2007138440A1 (pl)
ZA (1) ZA200808527B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140010198A (ko) 2006-06-12 2014-01-23 유씨비 파마 게엠베하 새로운 키랄 중간체, 그 키랄 중간체의 제조방법 및 톨테로딘, 페소테로딘 또는 그 활성대사물질의 제조에서 그 키랄 중간체의 사용
ES2533956T3 (es) 2009-05-11 2015-04-16 Ratiopharm Gmbh Desfesoterodina en forma de una sal de ácido tartárico
EP2281801B1 (en) 2009-07-27 2014-01-08 Crystal Pharma, S.A.U. Process for obtaining 3,3-diphenylpropylamines
IT1396373B1 (it) * 2009-10-29 2012-11-19 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina.
EP2364966A1 (en) 2010-03-09 2011-09-14 LEK Pharmaceuticals d.d. Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-3-phenylpropylamines, intermediates for making hydroxytolterodine
IT1401451B1 (it) * 2010-06-10 2013-07-26 Chemi Spa Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo.
WO2011158257A1 (en) 2010-06-18 2011-12-22 Panacea Biotec Ltd Preparation process of fesoterodine and intermediates
CN102329244A (zh) * 2010-07-13 2012-01-25 凯瑞斯德生化(苏州)有限公司 一种rs-托特罗定的制备方法及中间体化合物
WO2012025941A2 (en) 2010-08-25 2012-03-01 Cadila Healthcare Limited Processes for the preparation of fesoterodine
IT1403094B1 (it) 2010-12-09 2013-10-04 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina o un suo sale
JP6234999B2 (ja) 2012-05-04 2017-11-22 クリスタル ファルマ、エセ、ア、ウＣｒｙｓｔａｌ Ｐｈａｒｍａ，Ｓ．Ａ．Ｕ． 光学的に活性な３，３−ジフェニルプロピルアミンを調製するための方法
EP2760822B1 (en) 2012-06-14 2016-03-23 ratiopharm GmbH Desfesoterodine salts
ITMI20121232A1 (it) 2012-07-16 2014-01-17 Cambrex Profarmaco Milano Srl Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati
CN103044273B (zh) * 2012-11-29 2014-12-24 珠海保税区丽珠合成制药有限公司 一种酒石酸托特罗定的合成方法
WO2017137955A1 (en) 2016-02-14 2017-08-17 Celestis Pharmaceuticals Pvt. Ltd. Novel (r) and rac 3-(2-(allyloxy)-5-methylphenyl)-n,n-diisopropyl-3- phenylpropan-1-amine and its use for synthesis of (r) and rac-2-(3- (diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol
RU2652119C1 (ru) * 2016-12-14 2018-04-25 федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный технический университет" Способ получения производных хроман-2-аминов

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
KR20000057548A (ko) * 1996-12-13 2000-09-25 알프레드 엘. 미첼슨 광학적 전송물질 및 결합재
EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
DE19955190A1 (de) * 1999-11-16 2001-06-21 Sanol Arznei Schwarz Gmbh Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
SE9904850D0 (sv) 1999-12-30 1999-12-30 Pharmacia & Upjohn Ab Novel process and intermediates
DE10033016A1 (de) * 2000-07-07 2002-01-24 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen
US7173139B2 (en) 2001-06-29 2007-02-06 California Institute Of Technology Enantioselective 1,4-addition of aromatic nucleophiles to α,β-unsaturated aldehydes using chiral organic catalysts
WO2004091596A2 (en) * 2003-04-18 2004-10-28 Pharmacia & Upjohn Company Llc Combination therapies for chronic obstructive pulmonary disease (copd)

Also Published As

Publication number Publication date
ZA200808527B (en) 2009-11-25
PT2029567E (pt) 2010-11-08
EP2029567B1 (en) 2010-09-08
US8067594B2 (en) 2011-11-29
CN101454304B (zh) 2012-05-30
KR20090003353A (ko) 2009-01-09
CN101454304A (zh) 2009-06-10
IL194959A0 (en) 2009-08-03
HK1133425A1 (en) 2010-03-26
US20090306384A1 (en) 2009-12-10
CA2651978A1 (en) 2007-12-06
TW200804332A (en) 2008-01-16
AR061112A1 (es) 2008-08-06
CA2651978C (en) 2011-06-07
EP2029567A1 (en) 2009-03-04
RU2397163C2 (ru) 2010-08-20
JP5269349B2 (ja) 2013-08-21
JP2007314537A (ja) 2007-12-06
DE602007009096D1 (de) 2010-10-21
SG158070A1 (en) 2010-01-29
KR101087326B1 (ko) 2011-11-25
TWI343381B (en) 2011-06-11
AU2007266761A1 (en) 2007-12-06
ATE480531T1 (de) 2010-09-15
BRPI0712037A2 (pt) 2011-12-20
CY1110823T1 (el) 2015-06-10
ES2350056T3 (es) 2011-01-17
NZ571988A (en) 2011-09-30
RU2008141413A (ru) 2010-06-27
IL220430A0 (en) 2012-07-31
WO2007138440A1 (en) 2007-12-06
AU2007266761B2 (en) 2011-01-20
MX2008012976A (es) 2008-10-17
DK2029567T3 (da) 2010-11-29

Similar Documents

Publication Publication Date Title
IL220430A0 (en) Process for the production of benzopyran-2-ol derivatives
PL1903019T3 (pl) Sposób wytwarzania izoolefin
EP1999134A4 (en) PROCESS FOR PREPARING ANYHYDRUGAL ALCOHOLS
IL198847A0 (en) New process for the preparation of 2-imino-thiazolidin-4-one derivatives
EG26797A (en) Cement production process
EP1861408A4 (en) PROCESS FOR PRODUCING HYDROCHLOROSILANES
GB0707811D0 (en) Process for the production of crumb
EP1874948A4 (en) PROCESS FOR THE PREPARATION OF Y-GLUTAMYLCYSTEIN
EP2088136A4 (en) PROCESS FOR PRODUCING HYDROXYADAMANTANE-AMINE
HUE050656T2 (hu) Folyamat a biogáz elõállítására
IL205745A (en) METHOD FOR PREPARING HISTORY OF 2-FLUORO EASY-3-AMINO-ACRYLIC ACID
IL205082A0 (en) Process for the preparation of tetranorlabdane derivatives
PL2155679T3 (pl) Sposób wytwarzania pochodnych 4-formyloaminopiperydyny
IL187155A0 (en) Process for production of 4-biphenylazetidin-2-ones
EP1947083A4 (en) PROCESS FOR THE PREPARATION OF ARALKYLOXYPYRROLIDINE DERIVATIVES
ZA200710066B (en) Process for production of 4-biphenylylazetidin-2-ones
ZA200806840B (en) Improved process for producing nitroisourea derivatives
EP1864993A4 (en) METHOD FOR PRODUCING A GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE
EP2221290A4 (en) PROCESS FOR THE PREPARATION OF ALKOXYINDANONE DERIVATIVES
EP1985611A4 (en) PROCESS FOR THE PREPARATION OF O-METHYL-N-NITROISOHARNSTOFF
HU0600517D0 (en) Process for the production of benzylidene-rosiglitazone base
PL2194796T3 (pl) Sposób wytwarzania czekolady
HK1134925A1 (en) Method for the production of benzofuran-2-carboxamides
EP2077259A4 (en) PROCESS FOR THE PRODUCTION OF 2,6-DIMETHYL-1-NAPHTHALDEHYDE
GB201013148D0 (en) Novel dioctatin derivatives and process for production thereof