DK2187880T3 - Sammensætninger og fremgangsmåder til behandling af makuladegeneration - Google Patents

Sammensætninger og fremgangsmåder til behandling af makuladegeneration

Info

Publication number
DK2187880T3
DK2187880T3 DK08830106.4T DK08830106T DK2187880T3 DK 2187880 T3 DK2187880 T3 DK 2187880T3 DK 08830106 T DK08830106 T DK 08830106T DK 2187880 T3 DK2187880 T3 DK 2187880T3
Authority
DK
Denmark
Prior art keywords
compositions
methods
macular degeneration
treating macular
treating
Prior art date
Application number
DK08830106.4T
Other languages
English (en)
Inventor
Ilyas Washington
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40452355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2187880(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Columbia filed Critical Univ Columbia
Application granted granted Critical
Publication of DK2187880T3 publication Critical patent/DK2187880T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK08830106.4T 2007-09-12 2008-09-12 Sammensætninger og fremgangsmåder til behandling af makuladegeneration DK2187880T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99337907P 2007-09-12 2007-09-12
PCT/US2008/010676 WO2009035673A1 (en) 2007-09-12 2008-09-12 Compositions and methods for treating macular degeneration

Publications (1)

Publication Number Publication Date
DK2187880T3 true DK2187880T3 (da) 2014-03-10

Family

ID=40452355

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08830106.4T DK2187880T3 (da) 2007-09-12 2008-09-12 Sammensætninger og fremgangsmåder til behandling af makuladegeneration

Country Status (8)

Country Link
US (4) US8877809B2 (da)
EP (2) EP2187880B1 (da)
JP (2) JP5149388B2 (da)
DK (1) DK2187880T3 (da)
ES (1) ES2449150T3 (da)
PL (1) PL2187880T3 (da)
PT (1) PT2187880E (da)
WO (1) WO2009035673A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3326623A1 (en) 2003-03-14 2018-05-30 University of Washington Retinoid replacements and opsin agonists and methods for the use thereof
IN2012DN09335A (da) 2004-06-18 2015-08-21 Univ Washington
ES2449150T3 (es) 2007-09-12 2014-03-18 The Trustees Of Columbia University In The City Of New York Compuestos y métodos para tratar la degeneración muscular
AU2009213138B2 (en) 2008-02-11 2014-11-06 University Of Washington Methods for the treatment and prevention of age-related retinal dysfunction
US20090312438A1 (en) * 2008-06-13 2009-12-17 Bernstein Paul S Compositions and Methods for Attenuating the Formation of A2E in the Retinal Pigment Epithelium
WO2011034551A2 (en) 2009-09-15 2011-03-24 Qlt Inc. Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle
RU2622763C2 (ru) 2010-04-19 2017-06-19 Новелион Терапьютикс Инк. Лечебная схема и способы лечения или уменьшения нарушений зрения, связанных с дефицитом эндогенных ретиноидов
NZ629267A (en) 2012-03-01 2016-11-25 Quadra Logic Tech Inc Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency
JP6449764B2 (ja) 2012-06-07 2019-01-09 ベス イスラエル デアコネス メディカル センター インコーポレイテッド Pin1の阻害のための方法および組成物
EP3855181A1 (en) * 2014-02-13 2021-07-28 Katairo GmbH Compounds for the treatment of lipofuscin related diseases
WO2015143190A1 (en) * 2014-03-21 2015-09-24 Beth Israel Deaconess Medical Center, Inc. Enhanced atra-related compounds derived from structure-activity relationships and modeling for inhibiting pin1
WO2016011265A2 (en) 2014-07-17 2016-01-21 Beth Israel Deaconess Medical Center, Inc. Biomarkers for pin1-associated disorders
KR102276424B1 (ko) * 2014-10-06 2021-07-12 삼성전자주식회사 로-키나제 저해제를 포함하는 세포의 노화를 감소시키기 위한 조성물 및 그의 용도
US9173915B1 (en) 2014-10-10 2015-11-03 Peter F. Kador Antioxidant eye drops
US10548864B2 (en) 2015-03-12 2020-02-04 Beth Israel Deaconess Medical Center, Inc. Enhanced ATRA-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions
US20200025685A1 (en) * 2016-12-15 2020-01-23 Codiak Biosciences, Inc. Methods of measuring exosomes using intrinsic fluorescence
CN118121573A (zh) * 2022-12-01 2024-06-04 复旦大学 一种氘代维生素a及其衍生物的用途

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310764A (en) * 1992-05-08 1994-05-10 Steven Baranowitz Treatment of age related macular degeneration with beta-carotene
US5508456A (en) * 1993-07-30 1996-04-16 Ligand Pharmaceuticals Incorporated 9-cis tritium-labeled retinoids and intermediates, methods for their synthesis and methods for their use in discovering retinoid X receptor ligands
US5489611A (en) 1995-02-10 1996-02-06 Warner-Lambert Company Method for lowering plasma levels of lipoprotein (a)
US8198334B2 (en) 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
US6593104B1 (en) * 1999-02-12 2003-07-15 University Of Iowa Research Foundation Macular degeneration diagnostics and therapeutics
US20030149997A1 (en) 1999-02-19 2003-08-07 Hageman Gregory S. Diagnostics and therapeutics for arterial wall disruptive disorders
JP2003507030A (ja) * 1999-08-16 2003-02-25 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 18個のヒト分泌タンパク質
US20040009907A1 (en) * 2001-02-26 2004-01-15 Alsobrook John P. Proteins and nucleic acids encoding same
US20030032078A1 (en) * 2001-01-23 2003-02-13 Board Of Regents, The University Of Texas System Methods and compositions for the treatment of macular and retinal degenerations
NZ516873A (en) 2001-02-12 2003-11-28 Warner Lambert Co Compositions containing retinoids and erb inhibitors and their use in inhibiting retinoid skin damage
MXPA03008229A (es) 2001-03-14 2004-11-12 Lilly Co Eli Trienos fluorados y su uso como moduladores rxr.
US6660297B2 (en) 2001-03-23 2003-12-09 Bausch & Lomb Incorporated Nutritional supplement to treat macular degeneration
US20040121407A1 (en) 2002-09-06 2004-06-24 Elixir Pharmaceuticals, Inc. Regulation of the growth hormone/IGF-1 axis
AU2003297607A1 (en) 2002-12-02 2004-06-23 Genvec, Inc Materials and methods for treating ocular-related disorders
EP1628631A2 (en) 2003-06-05 2006-03-01 Achkar, Charles C. Methods of treating hyperproliferative cell disorders
US7267830B2 (en) * 2003-12-19 2007-09-11 Alcon, Inc. Composition and methods for inhibiting the progression macular degeneration and promoting healthy vision
FR2864871A1 (fr) 2004-01-06 2005-07-08 Thomson Licensing Sa Methode de decouverte d'un reseau domestique et appareil implementant la methode
US7309487B2 (en) * 2004-02-09 2007-12-18 George Inana Methods and compositions for detecting and treating retinal diseases
US7566808B2 (en) * 2004-02-17 2009-07-28 President And Fellows Of Harvard College Management of ophthalmologic disorders, including macular degeneration
US9421175B2 (en) * 2004-03-17 2016-08-23 Lars Michael Larsen Prevention of retinopathy by inhibition of the visual cycle
US20060089411A1 (en) * 2004-08-07 2006-04-27 Gierhart Dennis L Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin
WO2006033734A2 (en) * 2004-08-18 2006-03-30 Sirion Therapeutics, Inc. Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders
EP1804788A4 (en) * 2004-10-25 2008-05-21 Sirion Therapeutics Inc DETECTION AND ANALYSIS OF FLUORESCENT MOLECULES RELATING TO OPHTHALMOLOGY
AU2005304822B2 (en) * 2004-11-04 2008-10-16 Sirion Therapeutics, Inc. Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation
CA2584845C (en) * 2004-12-08 2009-02-17 Sirion Therapeutics, Inc. Methods, assays and compositions for treating retinol-related diseases
US20070014833A1 (en) * 2005-03-30 2007-01-18 Sirtris Pharmaceuticals, Inc. Treatment of eye disorders with sirtuin modulators
US20060292099A1 (en) 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
PL1888548T3 (pl) 2005-05-26 2013-01-31 Neuron Systems Inc Pochodna chinoliny do leczenia schorzeń siatkówki
UA81382C2 (en) * 2005-07-11 2007-12-25 Composition for treating retinol-related diseases by modulation of retinol binding
CN101316584A (zh) * 2005-09-27 2008-12-03 北海道公立大学法人札幌医科大学 用于预防及治疗由血管通透性亢进引起的眼病的医药
ES2449150T3 (es) 2007-09-12 2014-03-18 The Trustees Of Columbia University In The City Of New York Compuestos y métodos para tratar la degeneración muscular
US8677809B2 (en) 2008-06-16 2014-03-25 Oxford Instruments Plc Thermal measurements using multiple frequency atomic force microscopy
US8263601B2 (en) * 2009-02-27 2012-09-11 Concert Pharmaceuticals, Inc. Deuterium substituted xanthine derivatives
MX2011013880A (es) * 2009-06-18 2012-06-01 Concert Pharmaceuticals Inc Derivados de isoindolina-1,3-diona deuterados como inibidores de pde4 y tnf-alfa.

Also Published As

Publication number Publication date
US9486432B2 (en) 2016-11-08
EP2187880A1 (en) 2010-05-26
EP2187880B1 (en) 2013-12-18
US20170128403A1 (en) 2017-05-11
ES2449150T3 (es) 2014-03-18
USRE47045E1 (en) 2018-09-18
JP2010539168A (ja) 2010-12-16
PT2187880E (pt) 2014-03-25
JP5695017B2 (ja) 2015-04-01
US20110034554A1 (en) 2011-02-10
US20150133549A1 (en) 2015-05-14
EP2687208A1 (en) 2014-01-22
JP5149388B2 (ja) 2013-02-20
EP2187880A4 (en) 2010-09-08
WO2009035673A8 (en) 2009-07-02
PL2187880T3 (pl) 2014-05-30
WO2009035673A1 (en) 2009-03-19
US8877809B2 (en) 2014-11-04
JP2013049711A (ja) 2013-03-14

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