IL207495A - Useful compounds for age-related macular degeneration (amd) - Google Patents
Useful compounds for age-related macular degeneration (amd)Info
- Publication number
- IL207495A IL207495A IL207495A IL20749510A IL207495A IL 207495 A IL207495 A IL 207495A IL 207495 A IL207495 A IL 207495A IL 20749510 A IL20749510 A IL 20749510A IL 207495 A IL207495 A IL 207495A
- Authority
- IL
- Israel
- Prior art keywords
- amd
- age
- management
- macular degeneration
- compounds useful
- Prior art date
Links
- 206010064930 age-related macular degeneration Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 208000002780 macular degeneration Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79227806P | 2006-04-14 | 2006-04-14 | |
| PCT/AU2007/000490 WO2007118276A1 (en) | 2006-04-14 | 2007-04-13 | Method of treatment of age-related macular degeneration(amd) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL207495A0 IL207495A0 (en) | 2010-12-30 |
| IL207495A true IL207495A (en) | 2015-05-31 |
Family
ID=38608967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL207495A IL207495A (en) | 2006-04-14 | 2010-08-09 | Useful compounds for age-related macular degeneration (amd) |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20100144693A1 (enExample) |
| EP (2) | EP2514423A3 (enExample) |
| JP (1) | JP5290147B2 (enExample) |
| KR (2) | KR20080109096A (enExample) |
| CN (3) | CN101534826A (enExample) |
| AU (2) | AU2007240120A1 (enExample) |
| BR (2) | BRPI0722382A2 (enExample) |
| CA (1) | CA2683756A1 (enExample) |
| DK (1) | DK2012789T3 (enExample) |
| ES (1) | ES2437997T3 (enExample) |
| IL (1) | IL207495A (enExample) |
| NZ (2) | NZ572591A (enExample) |
| WO (1) | WO2007118276A1 (enExample) |
| ZA (2) | ZA200809493B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002950217A0 (en) | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
| PT1888548E (pt) | 2005-05-26 | 2012-10-30 | Neuron Systems Inc | Derivado de quinolina para o tratamento de doenças da retina |
| CN101589026B (zh) * | 2006-06-22 | 2013-10-16 | 普拉纳生物技术有限公司 | 治疗脑神经胶质瘤的方法 |
| JP2011530596A (ja) * | 2008-08-11 | 2011-12-22 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | ｔＲＮＡ合成酵素の阻害のためのハロフジノン類似体およびそれらの使用 |
| ES2634492T3 (es) | 2008-12-24 | 2017-09-28 | Prana Biotechnology Ltd | Compuestos de quinazolinona |
| AP2011005843A0 (en) | 2009-01-26 | 2011-08-31 | Joshua Lawrence Dunaief | Use of deferiprone for treatment and prevention ofiron-related eye disorders. |
| JP5885670B2 (ja) | 2009-12-11 | 2016-03-15 | アルデイラ セラピューティクス， インコーポレイテッド | 黄斑変性の処置のための組成物および方法 |
| WO2012122534A2 (en) | 2011-03-10 | 2012-09-13 | The Trustees Of Columbia University In The City Of New York | N-quinolin-benzensulfonamides and related compounds for the treatment of cancer, autoimmune disorders and inflammation |
| US10155742B2 (en) | 2012-01-13 | 2018-12-18 | President And Fellows Of Harvard College | Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions |
| CN105073714A (zh) * | 2012-12-20 | 2015-11-18 | 奥尔德拉医疗公司 | 迫位原醇 |
| JP6514114B2 (ja) | 2013-01-23 | 2019-05-15 | アルデイラ セラピューティクス， インコーポレイテッド | 毒性アルデヒド関連疾患および処置 |
| KR20150120380A (ko) | 2013-01-25 | 2015-10-27 | 알데이라 테라퓨틱스, 아이엔씨. | 황반 변성의 치료에서 신규한 트랩 |
| JP6784942B2 (ja) * | 2014-12-02 | 2020-11-18 | オールテリティ セラピューティクス リミテッド | ４Ｈ−ピリド［１，２−ａ］ピリミジン−４−オン化合物 |
| US10408982B2 (en) * | 2015-04-29 | 2019-09-10 | Triaplex Co., Ltd. | Polarizing film, preparation method thereof, polarizing lens comprising the same |
| US10781178B2 (en) * | 2015-08-12 | 2020-09-22 | The General Hospital Corporation | 8-hydroxyquinoline derivatives as diagnostic and therapeutic agents |
| WO2017035077A1 (en) | 2015-08-21 | 2017-03-02 | Aldeyra Therapeutics, Inc. | Deuterated compounds and uses thereof |
| US11008290B2 (en) * | 2015-09-24 | 2021-05-18 | University Of Florida Research Foundation, Incorporated | Halogenated quinoline derivatives as antimicrobial agents |
| EP3454858A4 (en) | 2016-05-09 | 2020-01-15 | Aldeyra Therapeutics, Inc. | COMBINATION TREATMENT OF FLAMMABLE CONDITIONS AND DISEASES OF THE EYE |
| WO2018000047A1 (en) * | 2016-07-01 | 2018-01-04 | Prana Biotechnology Limited | Method of treating immunoglobulin light chain amyloidosis |
| AU2018234919A1 (en) | 2017-03-16 | 2019-09-19 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| EP3694500A4 (en) | 2017-10-10 | 2021-06-30 | Aldeyra Therapeutics, Inc. | TREATMENT OF INFLAMMATORY DISORDERS |
| EP3801525A4 (en) | 2018-06-08 | 2022-03-23 | The General Hospital Corporation | PROLYL TRNA SYNTHETASE INHIBITORS |
| US12006298B2 (en) | 2018-08-06 | 2024-06-11 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| CN109232396B (zh) * | 2018-11-27 | 2020-07-03 | 聊城大学 | 酰胺吡啶类衍生物及其用途 |
| EP3962894A4 (en) | 2019-05-02 | 2023-01-11 | Aldeyra Therapeutics, Inc. | POLYMORPHIC COMPOUNDS AND USES THEREOF |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| EP4149470A4 (en) | 2020-05-13 | 2024-04-24 | Aldeyra Therapeutics, Inc. | Pharmaceutical formulations and uses thereof |
| WO2022006439A2 (en) * | 2020-07-02 | 2022-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compound embodiments for treating retinal degeneration and method embodiments of making and using the same |
| US12060334B2 (en) | 2021-03-12 | 2024-08-13 | University Of Florida Research Foundation, Incorporated | 3-substituted phenazine derivatives as antimicrobial agents |
| CN113214249B (zh) * | 2021-04-23 | 2023-09-19 | 成都大学 | 吡啶并[1,2-a]嘧啶-4-硫酮化合物的合成方法 |
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| US5314909A (en) * | 1993-03-17 | 1994-05-24 | Merck & Co., Inc. | Use of non-steroidal antiiflammatory agents in macular degeneration |
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| US5631373A (en) | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
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| US5801183A (en) | 1995-01-27 | 1998-09-01 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Aza and aza (N-oxy) analogs of glycine/NMDA receptor antagonists |
| ES2162319T3 (es) * | 1996-08-13 | 2001-12-16 | Gerolymatos P N Sa | Uso del agente quelante clioquinol para la fabricacion de una composicion farmaceutica para el tratamiento de la enfermedad de alzheimer. |
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| ATE354573T1 (de) | 2000-12-21 | 2007-03-15 | Vertex Pharma | ßPYRAZOLVERBINDUNGEN, DIE SICH ALS PROTEINKINASEINHIBITOREN EIGNENß |
| FR2819187A1 (fr) | 2001-01-10 | 2002-07-12 | Michel Xilinas | Utilisation des substances chelatrices pour le traitement et la prevention de la deferrescence oculaire |
| EP1389209B1 (en) | 2001-04-24 | 2009-04-08 | Purdue Research Foundation | Folate mimetics and folate-receptor binding conjugates thereof |
| FR2827599A1 (fr) | 2001-07-20 | 2003-01-24 | Neuro3D | Composes derives de quinoleine et quinoxaline,preparation et utilisations |
| JP2005504770A (ja) | 2001-08-17 | 2005-02-17 | メルク エンド カムパニー インコーポレーテッド | ５−スルホンアミド−８−ヒドロキシ−１，６−ナフチリジン−７−カルボキサミドの製造方法 |
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| EP1558585B1 (en) * | 2002-10-04 | 2013-09-25 | Prana Biotechnology Limited | Neurologically-active compounds |
| EP1617844A4 (en) * | 2003-04-03 | 2009-07-22 | Prana Biotechnology Ltd | TREATMENT OF NEUROLOGICAL DISEASES |
| CA2529256A1 (en) * | 2003-06-23 | 2004-12-29 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| CA2563038C (en) * | 2004-04-02 | 2013-10-29 | Gaik Beng Kok | Neurologically-active compounds |
| CA2593846A1 (en) * | 2005-01-14 | 2006-08-10 | The Regents Of The University Of California | Compositions and methods for inhibiting drusen formation and for diagnosing or treating drusen-related disorders |
| US20080207673A1 (en) * | 2005-05-04 | 2008-08-28 | Michel Xilinas | Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins |
| CN101589026B (zh) * | 2006-06-22 | 2013-10-16 | 普拉纳生物技术有限公司 | 治疗脑神经胶质瘤的方法 |
-
2007
- 2007-04-13 NZ NZ572591A patent/NZ572591A/en not_active IP Right Cessation
- 2007-04-13 BR BRPI0722382-0A patent/BRPI0722382A2/pt not_active Application Discontinuation
- 2007-04-13 WO PCT/AU2007/000490 patent/WO2007118276A1/en not_active Ceased
- 2007-04-13 CN CNA2007800222734A patent/CN101534826A/zh active Pending
- 2007-04-13 BR BRPI0710737-4A patent/BRPI0710737A2/pt not_active IP Right Cessation
- 2007-04-13 KR KR1020087027935A patent/KR20080109096A/ko not_active Ceased
- 2007-04-13 KR KR1020107020805A patent/KR20100110396A/ko not_active Ceased
- 2007-04-13 ZA ZA200809493A patent/ZA200809493B/xx unknown
- 2007-04-13 CN CN2010102559981A patent/CN101987849B/zh not_active Expired - Fee Related
- 2007-04-13 AU AU2007240120A patent/AU2007240120A1/en not_active Abandoned
- 2007-04-13 CN CN2011101585377A patent/CN102225930A/zh active Pending
- 2007-04-13 US US12/297,165 patent/US20100144693A1/en not_active Abandoned
- 2007-04-13 ES ES07718737.5T patent/ES2437997T3/es active Active
- 2007-04-13 EP EP12176495A patent/EP2514423A3/en not_active Withdrawn
- 2007-04-13 DK DK07718737.5T patent/DK2012789T3/da active
- 2007-04-13 EP EP07718737.5A patent/EP2012789B1/en not_active Not-in-force
- 2007-04-13 JP JP2009504530A patent/JP5290147B2/ja not_active Expired - Fee Related
- 2007-04-13 NZ NZ590271A patent/NZ590271A/en unknown
- 2007-04-13 CA CA002683756A patent/CA2683756A1/en not_active Abandoned
-
2010
- 2010-07-30 AU AU2010206074A patent/AU2010206074B2/en not_active Ceased
- 2010-08-09 IL IL207495A patent/IL207495A/en active IP Right Grant
- 2010-08-19 ZA ZA2010/05922A patent/ZA201005922B/en unknown
- 2010-11-23 US US12/952,425 patent/US20110071167A1/en not_active Abandoned
-
2013
- 2013-11-22 US US14/087,689 patent/US9163018B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NZ572591A (en) | 2012-01-12 |
| CN101987849B (zh) | 2013-05-08 |
| EP2012789B1 (en) | 2013-09-25 |
| AU2010206074A1 (en) | 2010-08-19 |
| EP2514423A3 (en) | 2012-12-19 |
| US20140088122A1 (en) | 2014-03-27 |
| AU2007240120A1 (en) | 2007-10-25 |
| EP2012789A1 (en) | 2009-01-14 |
| EP2012789A4 (en) | 2011-02-16 |
| NZ590271A (en) | 2011-12-22 |
| BRPI0710737A2 (pt) | 2011-05-10 |
| US20100144693A1 (en) | 2010-06-10 |
| AU2007240120A2 (en) | 2008-12-18 |
| JP5290147B2 (ja) | 2013-09-18 |
| BRPI0722382A2 (pt) | 2012-06-05 |
| KR20100110396A (ko) | 2010-10-12 |
| CN101987849A (zh) | 2011-03-23 |
| IL207495A0 (en) | 2010-12-30 |
| CN101534826A (zh) | 2009-09-16 |
| JP2009533356A (ja) | 2009-09-17 |
| EP2514423A2 (en) | 2012-10-24 |
| CN102225930A (zh) | 2011-10-26 |
| DK2012789T3 (da) | 2013-12-16 |
| ZA200809493B (en) | 2010-08-25 |
| WO2007118276A1 (en) | 2007-10-25 |
| US20110071167A1 (en) | 2011-03-24 |
| US9163018B2 (en) | 2015-10-20 |
| KR20080109096A (ko) | 2008-12-16 |
| CA2683756A1 (en) | 2007-10-25 |
| ES2437997T3 (es) | 2014-01-15 |
| AU2010206074B2 (en) | 2012-08-30 |
| ZA201005922B (en) | 2013-09-25 |
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