DK1921169T3 - Hybridiseringssonder til nukleinsyredetektion, universelle stamceller, fremgangsmåder og kits - Google Patents
Hybridiseringssonder til nukleinsyredetektion, universelle stamceller, fremgangsmåder og kitsInfo
- Publication number
- DK1921169T3 DK1921169T3 DK07075511.1T DK07075511T DK1921169T3 DK 1921169 T3 DK1921169 T3 DK 1921169T3 DK 07075511 T DK07075511 T DK 07075511T DK 1921169 T3 DK1921169 T3 DK 1921169T3
- Authority
- DK
- Denmark
- Prior art keywords
- kits
- probes
- nucleic acid
- target
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15200693A | 1993-11-12 | 1993-11-12 | |
EP95904104A EP0728218B1 (en) | 1993-11-12 | 1994-11-14 | Hybridization probes for nucleic acid detection, universal stems, methods and kits |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1921169T3 true DK1921169T3 (da) | 2012-06-04 |
Family
ID=22541183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07075511.1T DK1921169T3 (da) | 1993-11-12 | 1994-11-14 | Hybridiseringssonder til nukleinsyredetektion, universelle stamceller, fremgangsmåder og kits |
Country Status (10)
Country | Link |
---|---|
EP (3) | EP1921169B1 (da) |
JP (1) | JP4071277B2 (da) |
AT (2) | ATE382708T1 (da) |
AU (1) | AU697841B2 (da) |
CA (1) | CA2176348C (da) |
DE (1) | DE69435060T2 (da) |
DK (1) | DK1921169T3 (da) |
ES (1) | ES2386007T3 (da) |
PT (2) | PT1921169E (da) |
WO (1) | WO1995013399A1 (da) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7273749B1 (en) | 1990-06-04 | 2007-09-25 | University Of Utah Research Foundation | Container for carrying out and monitoring biological processes |
US7081226B1 (en) | 1996-06-04 | 2006-07-25 | University Of Utah Research Foundation | System and method for fluorescence monitoring |
US6576419B1 (en) | 1993-07-23 | 2003-06-10 | University Of Utah Research Foundation | Assay procedure using fluorogenic tracers |
US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
EP0826066B1 (en) | 1995-05-05 | 2000-09-13 | The Perkin-Elmer Corporation | Methods and reagents for combined pcr amplification and hybridization probing assay |
WO1997032044A1 (en) * | 1996-03-01 | 1997-09-04 | E.I. Du Pont De Nemours And Company | A method for the amplification and detection of a nucleic acid fragment of interest |
AU713667B2 (en) * | 1996-04-12 | 1999-12-09 | Phri Properties, Inc. | Detection probes, kits and assays |
US5955268A (en) * | 1996-04-26 | 1999-09-21 | Abbott Laboratories | Method and reagent for detecting multiple nucleic acid sequences in a test sample |
DE69727932T2 (de) * | 1996-06-04 | 2005-03-10 | University Of Utah Research Foundation, Salt Lake City | Vorrichtung und verfahren zur durchführung und überwachung von polymerase kettenreaktionen |
EP1179600B1 (en) | 1996-06-04 | 2005-05-11 | University Of Utah Research Foundation | Monitoring hybridization during PCR |
US6117635A (en) * | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
GB9715522D0 (en) * | 1997-07-24 | 1997-10-01 | Zeneca Ltd | Assays |
US5935791A (en) * | 1997-09-23 | 1999-08-10 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
US6485901B1 (en) | 1997-10-27 | 2002-11-26 | Boston Probes, Inc. | Methods, kits and compositions pertaining to linear beacons |
WO1999022018A2 (en) | 1997-10-27 | 1999-05-06 | Boston Probes, Inc. | Methods, kits and compositions pertaining to pna molecular beacons |
GB9725237D0 (en) * | 1997-11-29 | 1998-01-28 | Secr Defence | Amplification system |
GB9804355D0 (en) * | 1998-03-03 | 1998-04-22 | Zeneca Ltd | Method |
DE19811731A1 (de) * | 1998-03-18 | 1999-09-23 | November Ag Molekulare Medizin | Verfahren zum Nachweis einer Nukleotidsequenz |
WO1999049293A2 (en) | 1998-03-24 | 1999-09-30 | Boston Probes, Inc. | Methods, kits and compositions pertaining to detection complexes |
US6468743B1 (en) | 1998-05-18 | 2002-10-22 | Conagra Grocery Products Company | PCR techniques for detecting microbial contaminants in foodstuffs |
GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
WO2000001850A2 (en) | 1998-07-02 | 2000-01-13 | Gen-Probe Incorporated | Molecular torches |
US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
CA2375060A1 (en) | 1999-05-24 | 2000-11-30 | Invitrogen Corporation | Method for deblocking of labeled oligonucleotides |
US6440706B1 (en) | 1999-08-02 | 2002-08-27 | Johns Hopkins University | Digital amplification |
GB2359625B (en) | 1999-12-10 | 2004-10-20 | Molecular Light Tech Res Ltd | Monitoring oligonucleotide binding process using chemiluminescence quenching |
CA2393844A1 (en) * | 1999-12-14 | 2001-06-21 | Genovo, Inc. | Methods and compositions for the manufacture of replication incompetent adenovirus |
US6346384B1 (en) * | 2000-03-27 | 2002-02-12 | Dade Behring Inc. | Real-time monitoring of PCR using LOCI |
US6936443B2 (en) | 2000-04-03 | 2005-08-30 | Cytyc Corporation | Detection and typing of human papillomavirus using PNA probes |
JP2003529376A (ja) | 2000-04-03 | 2003-10-07 | サイティック コーポレイション | Pnaプローブを使用するヒトパピローマウイルスの検出およびタイピング |
GB0016813D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (4) |
CN1348096A (zh) | 2000-10-10 | 2002-05-08 | 栾国彦 | 一种均相特异性检测核酸的探针及应用方法 |
AU2002213416A1 (en) * | 2000-10-24 | 2002-05-06 | Yuri Khripin | Detecting specific nucleotide sequences |
US20020102557A1 (en) * | 2001-01-31 | 2002-08-01 | Gentile-Davey Maria C. | Self -complementary molecular probe |
WO2002063049A2 (en) * | 2001-02-02 | 2002-08-15 | Genome Therapeutics Corporation | Methods for determining a nucleotide at a specific location within a nucleic acid molecule |
EP1321520A4 (en) * | 2001-03-27 | 2003-09-03 | Nat Inst Of Advanced Ind Scien | NEW NUCLEIC ACID PROBE AND NEW METHOD FOR ANALYZING NUCLEIC ACIDS USING THE SAME |
US20030082547A1 (en) | 2001-08-27 | 2003-05-01 | Ewing Gregory J. | Non-fluorescent quencher compounds and biomolecular assays |
US6852491B2 (en) * | 2001-09-04 | 2005-02-08 | Abbott Laboratories | Amplification and detection reagents for HIV-1 |
CA2472026A1 (en) | 2002-01-07 | 2003-07-17 | Norchip A/S | Method for detecting human papillomavirus mrna |
ES2370169T3 (es) | 2002-06-14 | 2011-12-13 | Gen-Probe Incorporated | Composiciones y métodos para detectar el virus de la hepatitis b. |
EP1403382A3 (en) * | 2002-08-06 | 2004-05-06 | Roche Diagnostics GmbH | Improved fluorescent resonance energy transfer probes |
EP1431398A1 (en) | 2002-12-20 | 2004-06-23 | Evotec OAI AG | A method for detecting in a mixture an amount of analytes |
GB0317592D0 (en) | 2003-07-26 | 2003-08-27 | Astrazeneca Ab | Method |
CN103898207B (zh) * | 2003-08-01 | 2016-09-14 | 戴诺生物技术有限公司 | 自杂交多重靶核酸探针及其使用方法 |
US20050123975A1 (en) * | 2003-11-19 | 2005-06-09 | Applera Corporation | Methods for determining the degradation state or concentration of nucleic acids |
EP2453024B1 (en) | 2004-06-21 | 2017-12-06 | The Board of Trustees of The Leland Stanford Junior University | Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder |
JPWO2006049297A1 (ja) * | 2004-11-08 | 2008-05-29 | 独立行政法人理化学研究所 | 新規なヌクレオシド若しくはヌクレオチド誘導体及びその利用 |
EP1816195A4 (en) * | 2004-11-19 | 2009-06-03 | Wakunaga Pharma Co Ltd | NUCLEIC ACID FRAGMENTS FOR DETECTING NUCLEIC ACID AND METHOD FOR DETECTING NUCLEIC ACID |
GB0510979D0 (en) | 2005-05-28 | 2005-07-06 | Kbiosciences Ltd | Detection system for PCR assay |
CA2528222A1 (en) | 2005-10-31 | 2007-04-30 | Centre For Addiction And Mental Health | Slc1a1 marker for anxiety disorder |
DK2564864T3 (da) | 2005-11-12 | 2015-04-07 | Trustees Of The Leland Board Of | Fgf-2-relaterede fremgangsmåder til diagnosticering og behandling af depression |
US7759062B2 (en) | 2006-06-09 | 2010-07-20 | Third Wave Technologies, Inc. | T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection |
FR2906532B1 (fr) | 2006-09-28 | 2008-12-12 | Biomerieux Sa | Nouvel oligonucleotide marque |
ES2327956T3 (es) | 2006-10-12 | 2009-11-05 | Bio-Rad Pasteur | Sondas de doble hebra para la deteccion de acidos nucleicos, mediante fluorescencia. |
CA2705213C (en) | 2007-11-07 | 2016-10-04 | The University Of British Columbia | Microfluidic device and method of using same |
FR2933410B1 (fr) | 2008-07-04 | 2010-08-20 | Biomerieux Sa | Nouvelle sonde de detection |
DE102010012421B4 (de) | 2009-03-23 | 2023-04-20 | Vermicon Ag | Verfahren zum spezifischen Nachweis von Mikroorganismen |
WO2010112033A2 (en) | 2009-03-31 | 2010-10-07 | Østjysk Innovation A/S | Method for estimating the risk of having or developing multiple sclerosis using sequence polymorphisms in a specific region of chromosome x |
US8355927B2 (en) | 2010-11-05 | 2013-01-15 | Genomind, Llc | Neuropsychiatric test reports |
JP5334136B2 (ja) | 2009-09-09 | 2013-11-06 | 独立行政法人産業技術総合研究所 | 電気化学分子認識プローブ及びそれを用いた分子認識センサ並びにそれらを用いた電気化学的検出方法 |
CA3050896C (en) | 2010-04-21 | 2023-01-24 | Erik Berntorp | Genetic factors associated with inhibitor development in hemophilia a |
WO2012052758A1 (en) | 2010-10-22 | 2012-04-26 | Astrazeneca Ab | Response biomarkers for iap antagonists in human cancers |
JP5958034B2 (ja) | 2012-04-11 | 2016-07-27 | 富士レビオ株式会社 | 分子ビーコン型プローブを用いた標的核酸の検出方法 |
EP2895627A4 (en) * | 2012-09-17 | 2016-06-29 | Univ Brandeis | COMBINATION OF DNA-BINDING DYE AND PROBES FOR DNA SEQUENCE CHARACTERIZATION |
EP2722399A1 (en) | 2012-10-18 | 2014-04-23 | Roche Diagniostics GmbH | Method for preventing high molecular weight products during amplification |
US9816120B2 (en) * | 2013-01-09 | 2017-11-14 | The Penn State Research Foundation | Low sequence bias single-stranded DNA ligation |
MX2016000997A (es) | 2013-07-25 | 2016-04-19 | Dch Molecular Diagnostics Inc | Metodos y composiciones para detectar contaminacion bacteriana. |
CA2943951C (en) | 2013-10-17 | 2022-05-31 | Centre For Addiction And Mental Health | Genetic markers for antipsychotic induced weight gain and methods for use thereof |
EP3096757B1 (en) | 2014-01-24 | 2020-10-21 | AI Therapeutics, Inc. | Apilimod compositions for treating non-hodgkin's b cell lymphoma |
CA2940908C (en) | 2014-02-28 | 2023-05-09 | Centre For Addiction And Mental Health | Compositions and methods for the treatment and prevention of antipsychotic medication-induced weight gain |
ES2741399T3 (es) | 2014-11-07 | 2020-02-10 | Ai Therapeutics Inc | Apilimod para el uso en el tratamiento de cáncer renal |
US9957393B2 (en) | 2015-03-30 | 2018-05-01 | Enzo Biochem, Inc. | Monoazo dyes with cyclic amine as fluorescence quenchers |
CN109642253A (zh) | 2016-08-02 | 2019-04-16 | 豪夫迈·罗氏有限公司 | 用于提高核酸的扩增和检测/定量的效率的辅助寡核苷酸 |
RU2020114632A (ru) | 2017-09-27 | 2021-10-28 | ЭйАй ТЕРАПЬЮТИКС, ИНК. | Терапевтические способы, относящиеся к ингибиторам hsp90 |
CN112930354A (zh) * | 2018-07-24 | 2021-06-08 | 密歇根大学董事会 | 分子内动力学探针 |
US11584953B2 (en) * | 2019-02-12 | 2023-02-21 | 10X Genomics, Inc. | Methods for processing nucleic acid molecules |
GB201915346D0 (en) | 2019-06-21 | 2019-12-04 | Lumiradx Tech Ltd | Improvements in or relating to nicking enzymes |
WO2021051135A1 (en) | 2019-09-12 | 2021-03-18 | AI Therapeutics, Inc. | Pikfyve inhibitors for cancer therapy |
WO2021248063A2 (en) * | 2020-06-04 | 2021-12-09 | Logicink Corporation | Multi-sensing of nucleic acid and small molecule markers |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
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CA1190838A (en) | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
US4766062A (en) | 1984-05-07 | 1988-08-23 | Allied Corporation | Displacement polynucleotide assay method and polynucleotide complex reagent therefor |
US4822733A (en) | 1985-05-28 | 1989-04-18 | Amoco Corporation | Lifetime-resolved assay procedures |
CA1273552A (en) * | 1985-12-23 | 1990-09-04 | Michael J. Heller | Fluorescent stokes shift probes for polynucleotide hybridization assays |
ATE88761T1 (de) * | 1986-01-10 | 1993-05-15 | Amoco Corp | Kompetitiver homogener test. |
US4868103A (en) * | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
US5118801A (en) * | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
EP0428000A1 (en) * | 1989-11-03 | 1991-05-22 | Abbott Laboratories | Fluorogenic substrates for the detection of proteolytic enzyme activity |
WO1992014845A1 (en) * | 1991-02-26 | 1992-09-03 | Worcester Foundation For Experimental Biology | Diagnosing cystic fibrosis and other genetic diseases using fluorescence resonance energy transfer (fret) |
JP3085756B2 (ja) * | 1991-10-30 | 2000-09-11 | 株式会社日立製作所 | 核酸の検出方法 |
EP0601889A2 (en) * | 1992-12-10 | 1994-06-15 | Maine Medical Center Research Institute | Nucleic acid probes |
-
1994
- 1994-11-14 PT PT07075511T patent/PT1921169E/pt unknown
- 1994-11-14 JP JP51407995A patent/JP4071277B2/ja not_active Expired - Lifetime
- 1994-11-14 EP EP07075511A patent/EP1921169B1/en not_active Expired - Lifetime
- 1994-11-14 EP EP95904104A patent/EP0728218B1/en not_active Expired - Lifetime
- 1994-11-14 PT PT95904104T patent/PT728218E/pt unknown
- 1994-11-14 ES ES07075511T patent/ES2386007T3/es not_active Expired - Lifetime
- 1994-11-14 CA CA002176348A patent/CA2176348C/en not_active Expired - Lifetime
- 1994-11-14 AT AT95904104T patent/ATE382708T1/de not_active IP Right Cessation
- 1994-11-14 DK DK07075511.1T patent/DK1921169T3/da active
- 1994-11-14 EP EP10184995A patent/EP2423322A1/en not_active Withdrawn
- 1994-11-14 DE DE69435060T patent/DE69435060T2/de not_active Expired - Lifetime
- 1994-11-14 AU AU12921/95A patent/AU697841B2/en not_active Expired
- 1994-11-14 AT AT07075511T patent/ATE545711T1/de active
- 1994-11-14 WO PCT/US1994/013415 patent/WO1995013399A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP0728218A4 (en) | 1998-06-17 |
ATE545711T1 (de) | 2012-03-15 |
CA2176348A1 (en) | 1995-05-18 |
PT728218E (pt) | 2008-04-08 |
AU697841B2 (en) | 1998-10-15 |
EP0728218A1 (en) | 1996-08-28 |
EP0728218B1 (en) | 2008-01-02 |
EP1921169A1 (en) | 2008-05-14 |
CA2176348C (en) | 2004-11-02 |
PT1921169E (pt) | 2012-05-23 |
DE69435060T2 (de) | 2009-01-02 |
AU1292195A (en) | 1995-05-29 |
DE69435060D1 (de) | 2008-02-14 |
EP2423322A1 (en) | 2012-02-29 |
EP1921169B1 (en) | 2012-02-15 |
ES2386007T3 (es) | 2012-08-07 |
JP4071277B2 (ja) | 2008-04-02 |
JPH09504950A (ja) | 1997-05-20 |
ATE382708T1 (de) | 2008-01-15 |
WO1995013399A1 (en) | 1995-05-18 |
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