ATE545711T1 - Hybridisierungssonden zur nukleinsäuredetektion sowie universelle stämme, verfahren und kits - Google Patents
Hybridisierungssonden zur nukleinsäuredetektion sowie universelle stämme, verfahren und kitsInfo
- Publication number
- ATE545711T1 ATE545711T1 AT07075511T AT07075511T ATE545711T1 AT E545711 T1 ATE545711 T1 AT E545711T1 AT 07075511 T AT07075511 T AT 07075511T AT 07075511 T AT07075511 T AT 07075511T AT E545711 T1 ATE545711 T1 AT E545711T1
- Authority
- AT
- Austria
- Prior art keywords
- kits
- probes
- target
- nucleic acid
- universal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15200693A | 1993-11-12 | 1993-11-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE545711T1 true ATE545711T1 (de) | 2012-03-15 |
Family
ID=22541183
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95904104T ATE382708T1 (de) | 1993-11-12 | 1994-11-14 | Hybridisierungsprobe zur nukleinsäuredetektion, universelle stammstrukturen, methoden und reagentiensätze |
AT07075511T ATE545711T1 (de) | 1993-11-12 | 1994-11-14 | Hybridisierungssonden zur nukleinsäuredetektion sowie universelle stämme, verfahren und kits |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95904104T ATE382708T1 (de) | 1993-11-12 | 1994-11-14 | Hybridisierungsprobe zur nukleinsäuredetektion, universelle stammstrukturen, methoden und reagentiensätze |
Country Status (10)
Country | Link |
---|---|
EP (3) | EP0728218B1 (de) |
JP (1) | JP4071277B2 (de) |
AT (2) | ATE382708T1 (de) |
AU (1) | AU697841B2 (de) |
CA (1) | CA2176348C (de) |
DE (1) | DE69435060T2 (de) |
DK (1) | DK1921169T3 (de) |
ES (1) | ES2386007T3 (de) |
PT (2) | PT728218E (de) |
WO (1) | WO1995013399A1 (de) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7081226B1 (en) | 1996-06-04 | 2006-07-25 | University Of Utah Research Foundation | System and method for fluorescence monitoring |
US7273749B1 (en) | 1990-06-04 | 2007-09-25 | University Of Utah Research Foundation | Container for carrying out and monitoring biological processes |
US6576419B1 (en) | 1993-07-23 | 2003-06-10 | University Of Utah Research Foundation | Assay procedure using fluorogenic tracers |
US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
JP4040087B2 (ja) | 1995-05-05 | 2008-01-30 | アプレラ コーポレイション | Pcr増幅とハイブリダイゼーションプロービングアッセイとを組み合わせた方法およびそのための試薬 |
CA2246238A1 (en) * | 1996-03-01 | 1997-09-04 | E.I. Du Pont De Nemours And Company | A method for the amplification and detection of a nucleic acid fragment of interest |
EP0892808B1 (de) * | 1996-04-12 | 2008-05-14 | PHRI Properties, Inc. | Sonden, kits und assays |
US5955268A (en) * | 1996-04-26 | 1999-09-21 | Abbott Laboratories | Method and reagent for detecting multiple nucleic acid sequences in a test sample |
ES2304573T3 (es) * | 1996-06-04 | 2008-10-16 | University Of Utah Research Foundation | Recipiente para llevar a cabo y controlar procesos biologicos. |
US6174670B1 (en) | 1996-06-04 | 2001-01-16 | University Of Utah Research Foundation | Monitoring amplification of DNA during PCR |
US6117635A (en) * | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
GB9715522D0 (en) * | 1997-07-24 | 1997-10-01 | Zeneca Ltd | Assays |
US5935791A (en) * | 1997-09-23 | 1999-08-10 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
WO1999022018A2 (en) | 1997-10-27 | 1999-05-06 | Boston Probes, Inc. | Methods, kits and compositions pertaining to pna molecular beacons |
US6485901B1 (en) | 1997-10-27 | 2002-11-26 | Boston Probes, Inc. | Methods, kits and compositions pertaining to linear beacons |
GB9725237D0 (en) * | 1997-11-29 | 1998-01-28 | Secr Defence | Amplification system |
GB9804355D0 (en) * | 1998-03-03 | 1998-04-22 | Zeneca Ltd | Method |
DE19811731A1 (de) * | 1998-03-18 | 1999-09-23 | November Ag Molekulare Medizin | Verfahren zum Nachweis einer Nukleotidsequenz |
WO1999049293A2 (en) | 1998-03-24 | 1999-09-30 | Boston Probes, Inc. | Methods, kits and compositions pertaining to detection complexes |
US6468743B1 (en) | 1998-05-18 | 2002-10-22 | Conagra Grocery Products Company | PCR techniques for detecting microbial contaminants in foodstuffs |
GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
EP1092047B1 (de) | 1998-07-02 | 2009-08-26 | Gen-Probe Incorporated | Molekulare fackeln |
US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
CA2375060A1 (en) | 1999-05-24 | 2000-11-30 | Invitrogen Corporation | Method for deblocking of labeled oligonucleotides |
US6440706B1 (en) | 1999-08-02 | 2002-08-27 | Johns Hopkins University | Digital amplification |
GB2359625B (en) | 1999-12-10 | 2004-10-20 | Molecular Light Tech Res Ltd | Monitoring oligonucleotide binding process using chemiluminescence quenching |
EP1238091A2 (de) * | 1999-12-14 | 2002-09-11 | Genovo, Incorporated | Verfahren und zusammensetzungen zur herstellung von replicationsunfähigen adenovirus |
US6346384B1 (en) * | 2000-03-27 | 2002-02-12 | Dade Behring Inc. | Real-time monitoring of PCR using LOCI |
US6936443B2 (en) | 2000-04-03 | 2005-08-30 | Cytyc Corporation | Detection and typing of human papillomavirus using PNA probes |
US20020155427A1 (en) | 2000-04-03 | 2002-10-24 | Cohenford Menashi A. | Detection and typing of human papillomavirus using PNA probes |
GB0016813D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (4) |
CN1348096A (zh) | 2000-10-10 | 2002-05-08 | 栾国彦 | 一种均相特异性检测核酸的探针及应用方法 |
JP2004530410A (ja) * | 2000-10-24 | 2004-10-07 | インタージェン カンパニー | 特異的ヌクレオチド配列の検出 |
US20020102557A1 (en) * | 2001-01-31 | 2002-08-01 | Gentile-Davey Maria C. | Self -complementary molecular probe |
US20020142336A1 (en) * | 2001-02-02 | 2002-10-03 | Genome Therapeutics Corporation | Methods for determining a nucleotide at a specific location within a nucleic acid molecule |
US7273700B2 (en) * | 2001-03-27 | 2007-09-25 | National Institute Of Advanced Industrial Science And Technology | Nucleic acid probe and novel method of assaying nucleic acid using the same |
US20030082547A1 (en) | 2001-08-27 | 2003-05-01 | Ewing Gregory J. | Non-fluorescent quencher compounds and biomolecular assays |
US6852491B2 (en) * | 2001-09-04 | 2005-02-08 | Abbott Laboratories | Amplification and detection reagents for HIV-1 |
ES2282599T3 (es) | 2002-01-07 | 2007-10-16 | Norchip A/S | Metodo para detectar arnm del virus del papiloma humano. |
WO2003106714A1 (en) | 2002-06-14 | 2003-12-24 | Gen-Probe Incorporated | Compositions and methods for detecting hepatitis b virus |
EP1403382A3 (de) * | 2002-08-06 | 2004-05-06 | Roche Diagnostics GmbH | Verbesserte Proben für FRET |
EP1431398A1 (de) | 2002-12-20 | 2004-06-23 | Evotec OAI AG | Verfahren zum Nachweis die Menge eines Analyten in einer Mischung |
GB0317592D0 (en) | 2003-07-26 | 2003-08-27 | Astrazeneca Ab | Method |
WO2005012548A2 (en) * | 2003-08-01 | 2005-02-10 | Dynal Biotech Inc. | Self-hybridizing multiple target nucleic acid probes and methods of use |
US20050123975A1 (en) * | 2003-11-19 | 2005-06-09 | Applera Corporation | Methods for determining the degradation state or concentration of nucleic acids |
ATE551432T1 (de) | 2004-06-21 | 2012-04-15 | Univ Leland Stanford Junior | Bei manisch-depressiver erkrankung und/oder schwerer depressiver erkrankung unterschiedlich exprimierte gene und wege |
JPWO2006049297A1 (ja) * | 2004-11-08 | 2008-05-29 | 独立行政法人理化学研究所 | 新規なヌクレオシド若しくはヌクレオチド誘導体及びその利用 |
US20080311571A1 (en) * | 2004-11-19 | 2008-12-18 | Wakunaga Pharmaceutical Co., Ltd. | Nucleic Acid Fragments for Detecting Nucleic Acid and Method for Detecting Nucleic Acid |
GB0510979D0 (en) * | 2005-05-28 | 2005-07-06 | Kbiosciences Ltd | Detection system for PCR assay |
CA2528222A1 (en) | 2005-10-31 | 2007-04-30 | Centre For Addiction And Mental Health | Slc1a1 marker for anxiety disorder |
JP5366554B2 (ja) | 2005-11-12 | 2013-12-11 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | うつを診断および処置するためのfgf2関連方法 |
US7759062B2 (en) | 2006-06-09 | 2010-07-20 | Third Wave Technologies, Inc. | T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection |
FR2906532B1 (fr) | 2006-09-28 | 2008-12-12 | Biomerieux Sa | Nouvel oligonucleotide marque |
ATE437965T1 (de) * | 2006-10-12 | 2009-08-15 | Bio Rad Pasteur | Doppelsträngige sonden zur fluoreszenzdetektion von nukleinsäuren |
CA2705213C (en) | 2007-11-07 | 2016-10-04 | The University Of British Columbia | Microfluidic device and method of using same |
FR2933410B1 (fr) | 2008-07-04 | 2010-08-20 | Biomerieux Sa | Nouvelle sonde de detection |
DE102010012421B4 (de) | 2009-03-23 | 2023-04-20 | Vermicon Ag | Verfahren zum spezifischen Nachweis von Mikroorganismen |
WO2010112033A2 (en) | 2009-03-31 | 2010-10-07 | Østjysk Innovation A/S | Method for estimating the risk of having or developing multiple sclerosis using sequence polymorphisms in a specific region of chromosome x |
US8355927B2 (en) | 2010-11-05 | 2013-01-15 | Genomind, Llc | Neuropsychiatric test reports |
JP5334136B2 (ja) | 2009-09-09 | 2013-11-06 | 独立行政法人産業技術総合研究所 | 電気化学分子認識プローブ及びそれを用いた分子認識センサ並びにそれらを用いた電気化学的検出方法 |
CA2796561C (en) | 2010-04-21 | 2019-09-17 | Erik Berntorp | Genetic factors associated with inhibitor development in hemophilia a |
WO2012052758A1 (en) | 2010-10-22 | 2012-04-26 | Astrazeneca Ab | Response biomarkers for iap antagonists in human cancers |
JP5958034B2 (ja) | 2012-04-11 | 2016-07-27 | 富士レビオ株式会社 | 分子ビーコン型プローブを用いた標的核酸の検出方法 |
CA2885195A1 (en) * | 2012-09-17 | 2014-03-20 | Brandeis University | Combination of dsdna binding dye and probes for characterization of ssdna sequences |
EP2722399A1 (de) | 2012-10-18 | 2014-04-23 | Roche Diagniostics GmbH | Verfahren zur Vermeidung von Produkten mit hohem Molekulargewicht während einer Amplifikation |
WO2014110272A1 (en) * | 2013-01-09 | 2014-07-17 | The Penn State Research Foundation | Low sequence bias single-stranded dna ligation |
JP2016525359A (ja) | 2013-07-25 | 2016-08-25 | ディーシーエイチ モレキュラー ダイアグノスティクス, インコーポレイテッド | 細菌汚染を検出するための方法および組成物 |
WO2015054792A1 (en) | 2013-10-17 | 2015-04-23 | Centre For Addiction And Mental Health | Genetic markers for antipsychotic induced weight gain and methods for use thereof |
WO2015112888A1 (en) | 2014-01-24 | 2015-07-30 | Lam Therapeutics, Inc. | Apilimod compositions and methods for using same |
SG11201607137WA (en) | 2014-02-28 | 2016-09-29 | Camh | Compositions and methods for the treatment and prevention of antipsychotic medication-induced weight gain |
PL3215158T3 (pl) | 2014-11-07 | 2019-11-29 | Ai Therapeutics Inc | Apilimod do zastosowania do leczenia raka nerki |
US9957393B2 (en) | 2015-03-30 | 2018-05-01 | Enzo Biochem, Inc. | Monoazo dyes with cyclic amine as fluorescence quenchers |
CN109642253A (zh) | 2016-08-02 | 2019-04-16 | 豪夫迈·罗氏有限公司 | 用于提高核酸的扩增和检测/定量的效率的辅助寡核苷酸 |
WO2019067666A1 (en) | 2017-09-27 | 2019-04-04 | Lam Therapeutics, Inc. | THERAPEUTIC METHODS RELATING TO HSP90 INHIBITORS |
WO2020023503A1 (en) * | 2018-07-24 | 2020-01-30 | The Regents Of The University Of Michigan | Intramolecular kinetic probes |
SG11202108788TA (en) * | 2019-02-12 | 2021-09-29 | 10X Genomics Inc | Methods for processing nucleic acid molecules |
GB201915346D0 (en) | 2019-06-21 | 2019-12-04 | Lumiradx Tech Ltd | Improvements in or relating to nicking enzymes |
AR119934A1 (es) | 2019-09-12 | 2022-01-19 | Ai Therapeutics Inc | Inhibidores de pikfyve para terapia contra el cáncer |
US20230212702A1 (en) * | 2020-06-04 | 2023-07-06 | Logicink Corporation | Multi-sensing of nucleic acid and small molecule markers |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1190838A (en) | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
US4766062A (en) * | 1984-05-07 | 1988-08-23 | Allied Corporation | Displacement polynucleotide assay method and polynucleotide complex reagent therefor |
US4822733A (en) | 1985-05-28 | 1989-04-18 | Amoco Corporation | Lifetime-resolved assay procedures |
CA1273552A (en) * | 1985-12-23 | 1990-09-04 | Michael J. Heller | Fluorescent stokes shift probes for polynucleotide hybridization assays |
ATE88761T1 (de) * | 1986-01-10 | 1993-05-15 | Amoco Corp | Kompetitiver homogener test. |
US4868103A (en) * | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
US5118801A (en) * | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
EP0428000A1 (de) * | 1989-11-03 | 1991-05-22 | Abbott Laboratories | Fluorogene Substrate zum Nachweis von proteolytischer Enzymaktivität |
WO1992014845A1 (en) * | 1991-02-26 | 1992-09-03 | Worcester Foundation For Experimental Biology | Diagnosing cystic fibrosis and other genetic diseases using fluorescence resonance energy transfer (fret) |
JP3085756B2 (ja) * | 1991-10-30 | 2000-09-11 | 株式会社日立製作所 | 核酸の検出方法 |
EP0601889A2 (de) * | 1992-12-10 | 1994-06-15 | Maine Medical Center Research Institute | Nukleinsäure-Sonden |
-
1994
- 1994-11-14 AU AU12921/95A patent/AU697841B2/en not_active Expired
- 1994-11-14 AT AT95904104T patent/ATE382708T1/de not_active IP Right Cessation
- 1994-11-14 AT AT07075511T patent/ATE545711T1/de active
- 1994-11-14 ES ES07075511T patent/ES2386007T3/es not_active Expired - Lifetime
- 1994-11-14 PT PT95904104T patent/PT728218E/pt unknown
- 1994-11-14 CA CA002176348A patent/CA2176348C/en not_active Expired - Lifetime
- 1994-11-14 EP EP95904104A patent/EP0728218B1/de not_active Expired - Lifetime
- 1994-11-14 JP JP51407995A patent/JP4071277B2/ja not_active Expired - Lifetime
- 1994-11-14 DE DE69435060T patent/DE69435060T2/de not_active Expired - Lifetime
- 1994-11-14 EP EP07075511A patent/EP1921169B1/de not_active Expired - Lifetime
- 1994-11-14 WO PCT/US1994/013415 patent/WO1995013399A1/en active IP Right Grant
- 1994-11-14 DK DK07075511.1T patent/DK1921169T3/da active
- 1994-11-14 PT PT07075511T patent/PT1921169E/pt unknown
- 1994-11-14 EP EP10184995A patent/EP2423322A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1921169A1 (de) | 2008-05-14 |
CA2176348A1 (en) | 1995-05-18 |
DE69435060T2 (de) | 2009-01-02 |
CA2176348C (en) | 2004-11-02 |
EP0728218A4 (de) | 1998-06-17 |
JPH09504950A (ja) | 1997-05-20 |
WO1995013399A1 (en) | 1995-05-18 |
PT1921169E (pt) | 2012-05-23 |
EP0728218B1 (de) | 2008-01-02 |
EP0728218A1 (de) | 1996-08-28 |
ES2386007T3 (es) | 2012-08-07 |
JP4071277B2 (ja) | 2008-04-02 |
ATE382708T1 (de) | 2008-01-15 |
DE69435060D1 (de) | 2008-02-14 |
AU697841B2 (en) | 1998-10-15 |
AU1292195A (en) | 1995-05-29 |
EP1921169B1 (de) | 2012-02-15 |
DK1921169T3 (da) | 2012-06-04 |
PT728218E (pt) | 2008-04-08 |
EP2423322A1 (de) | 2012-02-29 |
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