ES2058112T3 - Sondas de hibridacion. - Google Patents

Sondas de hibridacion.

Info

Publication number
ES2058112T3
ES2058112T3 ES87304433T ES87304433T ES2058112T3 ES 2058112 T3 ES2058112 T3 ES 2058112T3 ES 87304433 T ES87304433 T ES 87304433T ES 87304433 T ES87304433 T ES 87304433T ES 2058112 T3 ES2058112 T3 ES 2058112T3
Authority
ES
Spain
Prior art keywords
hybrid
probe
base sequence
nucleotide
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87304433T
Other languages
English (en)
Inventor
Francis Joseph Carr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10598059&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2058112(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Application granted granted Critical
Publication of ES2058112T3 publication Critical patent/ES2058112T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Surgical Instruments (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)

Abstract

UN METODO PARA DISCRIMINAR UNA SECUENCIA DE BASE ESPECIFICA DE UNA SECUENCIA DE BASE VARIANTE CONSISTE EN SOMETER SEGMENTOS ADYACENTES DE UNA SECUENCIA DE BASE-OBJETIVO A HIBRIDACION CON UNA PRIMERA PROBETA DE NUCLEOTIDO Y CON UNA SEGUNDA PROBETA DE NUCLEOTIDO PARA FORMAR UN HIBRIDO, SIENDO LA SECUENCIA DE NUCLEOTIDOS DE LA PRIMERA Y SEGUNDA PROBETAS TALES QUE CUANDO FORMAN UN HIBRIDO DE PROBETA PARTIDA CON UNA SECUENCIA OBJETIVO SUPLEMENTARIA PUEDEN SER POSTERIORMENTE LIGADAS SOMETIENDO A CUALQUIER HIBRIDO OBTENIDO, TAMBIEN SE DESCRIBEN PROBETAS DE HIBRIDACION Y CONJUNTO DE ELEMENTOS PARA USAR EN ESTE METODO.
ES87304433T 1986-05-19 1987-05-19 Sondas de hibridacion. Expired - Lifetime ES2058112T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868612087A GB8612087D0 (en) 1986-05-19 1986-05-19 Hybridisation probes

Publications (1)

Publication Number Publication Date
ES2058112T3 true ES2058112T3 (es) 1994-11-01

Family

ID=10598059

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87304433T Expired - Lifetime ES2058112T3 (es) 1986-05-19 1987-05-19 Sondas de hibridacion.

Country Status (7)

Country Link
EP (1) EP0246864B2 (es)
JP (2) JP2622255B2 (es)
AT (1) ATE108490T1 (es)
DE (1) DE3750198T3 (es)
ES (1) ES2058112T3 (es)
GB (1) GB8612087D0 (es)
HK (1) HK125195A (es)

Families Citing this family (87)

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US4988617A (en) * 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US8148065B1 (en) * 1988-04-06 2012-04-03 City Of Hope Ligation amplification of nucleic acid sequences
CA1341584C (en) * 1988-04-06 2008-11-18 Bruce Wallace Method of amplifying and detecting nucleic acid sequences
DE68927373T2 (de) * 1988-06-24 1997-03-20 Amgen Inc Verfahren und mittel zum nachweis von nukleinsäuresequenzen
US6004826A (en) * 1988-07-20 1999-12-21 David Segev Repair-mediated process for amplifying and detecting nucleic acid sequences
ATE138106T1 (de) * 1988-07-20 1996-06-15 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
US5382511A (en) * 1988-08-02 1995-01-17 Gene Tec Corporation Method for studying nucleic acids within immobilized specimens
US5185243A (en) * 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
GB2225112A (en) * 1988-11-22 1990-05-23 Ici Plc Hybridisation probes
CA2005927A1 (en) * 1988-12-21 1990-06-21 Chander Bahl Method of preparing nucleotide probes using a bridging complement
ATE142272T1 (de) * 1989-01-19 1996-09-15 Behringwerke Ag Nukleinsäure-amplifikation unter verwendung eines einzelprimers
EP0385410B1 (en) * 1989-02-28 1996-10-02 Canon Kabushiki Kaisha Partially double-stranded oligonucleotide and method for forming oligonucleotide
CA2012983A1 (en) * 1989-03-27 1990-09-27 Sydney Brenner Process for nucleic acid detection by binary amplification
US5091302A (en) * 1989-04-27 1992-02-25 The Blood Center Of Southeastern Wisconsin, Inc. Polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic applications thereof
CA2035010C (en) * 1990-01-26 1996-12-10 Keith C. Backman Method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
US5516663A (en) * 1990-01-26 1996-05-14 Abbott Laboratories Ligase chain reaction with endonuclease IV correction and contamination control
US5427930A (en) * 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US5573907A (en) * 1990-01-26 1996-11-12 Abbott Laboratories Detecting and amplifying target nucleic acids using exonucleolytic activity
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
CA2040896C (en) * 1990-04-20 2002-01-29 Edwin F. Ullman Double receptor polynucleotide assay method
US5494810A (en) * 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5846710A (en) * 1990-11-02 1998-12-08 St. Louis University Method for the detection of genetic diseases and gene sequence variations by single nucleotide primer extension
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
US5981176A (en) * 1992-06-17 1999-11-09 City Of Hope Method of detecting and discriminating between nucleic acid sequences
US5695933A (en) * 1993-05-28 1997-12-09 Massachusetts Institute Of Technology Direct detection of expanded nucleotide repeats in the human genome
AU8132194A (en) * 1993-11-03 1995-05-23 Molecular Tool, Inc. Single nucleotide polymorphisms and their use in genetic analysis
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US5552278A (en) * 1994-04-04 1996-09-03 Spectragen, Inc. DNA sequencing by stepwise ligation and cleavage
US5831065A (en) * 1994-04-04 1998-11-03 Lynx Therapeutics, Inc. Kits for DNA sequencing by stepwise ligation and cleavage
US5714330A (en) * 1994-04-04 1998-02-03 Lynx Therapeutics, Inc. DNA sequencing by stepwise ligation and cleavage
US6013445A (en) * 1996-06-06 2000-01-11 Lynx Therapeutics, Inc. Massively parallel signature sequencing by ligation of encoded adaptors
USRE43097E1 (en) 1994-10-13 2012-01-10 Illumina, Inc. Massively parallel signature sequencing by ligation of encoded adaptors
GB9507238D0 (en) * 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
US5728526A (en) * 1995-06-07 1998-03-17 Oncor, Inc. Method for analyzing a nucleotide sequence
WO1996041011A1 (en) * 1995-06-07 1996-12-19 Lynx Therapeutics, Inc. Oligonucleotide tags for sorting and identification
DE19610255B4 (de) * 1996-03-15 2004-11-04 Universität Heidelberg Verfahren zur Herstellung von Nukleinsäuresequenzen und Verfahren zum Nachweis von Translokationen zwischen Chromosomen
WO1997035033A1 (en) 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
ATE366418T1 (de) 1996-04-25 2007-07-15 Bioarray Solutions Ltd Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
WO1998014592A2 (en) 1996-10-01 1998-04-09 Geron Corporation Telomerase reverse transcriptase
AU744445B2 (en) 1997-04-24 2002-02-21 University Of Washington Targeted gene modification by parvoviral vectors
US6960457B1 (en) 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
AU1827200A (en) * 1998-11-25 2000-06-13 Isis Pharmaceuticals, Inc. (in situ) binary synthesis of biologically effective molecules
US6492111B1 (en) * 1998-11-25 2002-12-10 Isis Pharmaceuticals, Inc. In situ binary synthesis of biologically effective molecules
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WO2000062036A1 (en) * 1999-04-12 2000-10-19 Nanogen/Becton Dickinson Partnership Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology
EP1136568A4 (en) * 1999-10-04 2004-12-15 Olympus Optical Corp Ltd METHOD FOR DETERMINING NUCLEIC ACID
JP4598338B2 (ja) * 1999-10-04 2010-12-15 オリンパス株式会社 核酸検出方法
JP3668075B2 (ja) * 1999-10-12 2005-07-06 光夫 板倉 遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたＳＮＰｓ高速スコアリング方法
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US7108998B2 (en) 2001-06-11 2006-09-19 Ecopia Biosciences Inc. Nucleic acid fragment encoding an NRPS for the biosynthesis of anthramycin
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US7291490B2 (en) 2001-06-11 2007-11-06 Ecopia Biosciences Inc. Nucleic acid fragment encoding an NRPS for the biosynthesis of anthramycin
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US20040002073A1 (en) 2001-10-15 2004-01-01 Li Alice Xiang Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
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Also Published As

Publication number Publication date
GB8612087D0 (en) 1986-06-25
DE3750198T2 (de) 1995-01-26
JP2622255B2 (ja) 1997-06-18
DE3750198D1 (de) 1994-08-18
EP0246864B1 (en) 1994-07-13
ATE108490T1 (de) 1994-07-15
EP0246864A3 (en) 1989-08-23
HK125195A (en) 1995-08-11
JPH09182591A (ja) 1997-07-15
EP0246864B2 (en) 2007-05-23
EP0246864A2 (en) 1987-11-25
JP2683336B2 (ja) 1997-11-26
JPS6322197A (ja) 1988-01-29
DE3750198T3 (de) 2008-01-03

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