|
CA1323293C
(en)
*
|
1987-12-11 |
1993-10-19 |
Keith C. Backman |
Assay using template-dependent nucleic acid probe reorganization
|
|
US5449602A
(en)
*
|
1988-01-13 |
1995-09-12 |
Amoco Corporation |
Template-directed photoligation
|
|
US5093245A
(en)
*
|
1988-01-26 |
1992-03-03 |
Applied Biosystems |
Labeling by simultaneous ligation and restriction
|
|
IE61148B1
(en)
*
|
1988-03-10 |
1994-10-05 |
Ici Plc |
Method of detecting nucleotide sequences
|
|
JP2856804B2
(ja)
*
|
1988-03-24 |
1999-02-10 |
ユニバーシティ オブ アイオワ リサーチ ファウンデイション |
標識された相補的核酸プローブを開裂する触媒反応の補因子としての活性に基づく核酸配列検出のための触媒ハイブリッド形成系
|
|
US4988617A
(en)
*
|
1988-03-25 |
1991-01-29 |
California Institute Of Technology |
Method of detecting a nucleotide change in nucleic acids
|
|
US8148065B1
(en)
*
|
1988-04-06 |
2012-04-03 |
City Of Hope |
Ligation amplification of nucleic acid sequences
|
|
CA1341584C
(en)
*
|
1988-04-06 |
2008-11-18 |
Bruce Wallace |
Method of amplifying and detecting nucleic acid sequences
|
|
JP2801051B2
(ja)
*
|
1988-06-24 |
1998-09-21 |
アムジエン・インコーポレーテツド |
核酸塩基配列を検出するための方法及び試薬
|
|
DE68926504T2
(de)
*
|
1988-07-20 |
1996-09-12 |
David Segev |
Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
|
|
US6004826A
(en)
*
|
1988-07-20 |
1999-12-21 |
David Segev |
Repair-mediated process for amplifying and detecting nucleic acid sequences
|
|
US5382511A
(en)
*
|
1988-08-02 |
1995-01-17 |
Gene Tec Corporation |
Method for studying nucleic acids within immobilized specimens
|
|
US5185243A
(en)
*
|
1988-08-25 |
1993-02-09 |
Syntex (U.S.A.) Inc. |
Method for detection of specific nucleic acid sequences
|
|
GB2225112A
(en)
*
|
1988-11-22 |
1990-05-23 |
Ici Plc |
Hybridisation probes
|
|
CA2005927A1
(en)
*
|
1988-12-21 |
1990-06-21 |
Chander Bahl |
Method of preparing nucleotide probes using a bridging complement
|
|
DE69028325T2
(de)
*
|
1989-01-19 |
1997-04-17 |
Behringwerke Ag |
Nukleinsäure-Amplifikation unter Verwendung eines Einzelprimers
|
|
DE69028725T2
(de)
*
|
1989-02-28 |
1997-03-13 |
Canon Kk |
Partiell doppelsträngiges Oligonukleotid und Verfahren zu seiner Bildung
|
|
CA2012983A1
(en)
*
|
1989-03-27 |
1990-09-27 |
Sydney Brenner |
Process for nucleic acid detection by binary amplification
|
|
US5091302A
(en)
*
|
1989-04-27 |
1992-02-25 |
The Blood Center Of Southeastern Wisconsin, Inc. |
Polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic applications thereof
|
|
US5573907A
(en)
*
|
1990-01-26 |
1996-11-12 |
Abbott Laboratories |
Detecting and amplifying target nucleic acids using exonucleolytic activity
|
|
US5427930A
(en)
*
|
1990-01-26 |
1995-06-27 |
Abbott Laboratories |
Amplification of target nucleic acids using gap filling ligase chain reaction
|
|
ATE137269T1
(de)
*
|
1990-01-26 |
1996-05-15 |
Abbott Lab |
Verbessertes verfahren zur amplifikation von nuklein säurezielsequenz, einsetzbar für die polymerase und ligasekettenreaktion
|
|
US5516663A
(en)
*
|
1990-01-26 |
1996-05-14 |
Abbott Laboratories |
Ligase chain reaction with endonuclease IV correction and contamination control
|
|
US6013431A
(en)
|
1990-02-16 |
2000-01-11 |
Molecular Tool, Inc. |
Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
|
|
EP0453301A3
(en)
*
|
1990-04-20 |
1993-07-21 |
Syntex (U.S.A.) Inc. |
Double receptor polynucleotide assay method
|
|
US5494810A
(en)
*
|
1990-05-03 |
1996-02-27 |
Cornell Research Foundation, Inc. |
Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
|
|
US5210015A
(en)
*
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
|
US5846710A
(en)
*
|
1990-11-02 |
1998-12-08 |
St. Louis University |
Method for the detection of genetic diseases and gene sequence variations by single nucleotide primer extension
|
|
US6004744A
(en)
|
1991-03-05 |
1999-12-21 |
Molecular Tool, Inc. |
Method for determining nucleotide identity through extension of immobilized primer
|
|
US5981176A
(en)
*
|
1992-06-17 |
1999-11-09 |
City Of Hope |
Method of detecting and discriminating between nucleic acid sequences
|
|
US5695933A
(en)
*
|
1993-05-28 |
1997-12-09 |
Massachusetts Institute Of Technology |
Direct detection of expanded nucleotide repeats in the human genome
|
|
AU8132194A
(en)
*
|
1993-11-03 |
1995-05-23 |
Molecular Tool, Inc. |
Single nucleotide polymorphisms and their use in genetic analysis
|
|
WO1995020679A1
(en)
*
|
1994-01-26 |
1995-08-03 |
Hybridon, Inc. |
Method of detecting sub-ppb levels of oligonucleotides in biological fluids
|
|
EP0754240B1
(de)
*
|
1994-02-07 |
2003-08-20 |
Beckman Coulter, Inc. |
Ligase/polymerase-vermittelte analyse genetischer elemente von einzelnukleotid-polymorphismen und ihre verwendung in der genetischen analyse
|
|
US5831065A
(en)
*
|
1994-04-04 |
1998-11-03 |
Lynx Therapeutics, Inc. |
Kits for DNA sequencing by stepwise ligation and cleavage
|
|
US5552278A
(en)
*
|
1994-04-04 |
1996-09-03 |
Spectragen, Inc. |
DNA sequencing by stepwise ligation and cleavage
|
|
US5714330A
(en)
*
|
1994-04-04 |
1998-02-03 |
Lynx Therapeutics, Inc. |
DNA sequencing by stepwise ligation and cleavage
|
|
USRE43097E1
(en)
|
1994-10-13 |
2012-01-10 |
Illumina, Inc. |
Massively parallel signature sequencing by ligation of encoded adaptors
|
|
US6013445A
(en)
*
|
1996-06-06 |
2000-01-11 |
Lynx Therapeutics, Inc. |
Massively parallel signature sequencing by ligation of encoded adaptors
|
|
GB9507238D0
(en)
*
|
1995-04-07 |
1995-05-31 |
Isis Innovation |
Detecting dna sequence variations
|
|
US5728526A
(en)
*
|
1995-06-07 |
1998-03-17 |
Oncor, Inc. |
Method for analyzing a nucleotide sequence
|
|
HUP9900910A2
(hu)
*
|
1995-06-07 |
1999-07-28 |
Lynx Therapeutics, Inc. |
Oligonukleotid jelzések osztályozáshoz és azonosításhoz
|
|
DE19610255B4
(de)
|
1996-03-15 |
2004-11-04 |
Universität Heidelberg |
Verfahren zur Herstellung von Nukleinsäuresequenzen und Verfahren zum Nachweis von Translokationen zwischen Chromosomen
|
|
AU2320597A
(en)
|
1996-03-19 |
1997-10-10 |
Molecular Tool, Inc. |
Method for determining the nucleotide sequence of a polynucleotide
|
|
ES2288760T3
(es)
|
1996-04-25 |
2008-01-16 |
Bioarray Solutions Ltd. |
Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
|
|
EP0841396B2
(de)
|
1996-10-01 |
2012-04-11 |
Geron Corporation |
Katalytische Untereinheit der menschlichen Telomerase
|
|
AU744445B2
(en)
|
1997-04-24 |
2002-02-21 |
University Of Washington |
Targeted gene modification by parvoviral vectors
|
|
US6960457B1
(en)
|
1997-09-04 |
2005-11-01 |
Stanford University |
Reversible immobilization of arginine-tagged moieties on a silicate surface
|
|
US6492111B1
(en)
*
|
1998-11-25 |
2002-12-10 |
Isis Pharmaceuticals, Inc. |
In situ binary synthesis of biologically effective molecules
|
|
WO2000031302A1
(en)
*
|
1998-11-25 |
2000-06-02 |
Isis Pharmaceuticals, Inc. |
In situ binary synthesis of biologically effective molecules
|
|
US7014994B1
(en)
|
1999-03-19 |
2006-03-21 |
Cornell Research Foundation,Inc. |
Coupled polymerase chain reaction-restriction-endonuclease digestion-ligase detection reaction process
|
|
WO2000062036A1
(en)
*
|
1999-04-12 |
2000-10-19 |
Nanogen/Becton Dickinson Partnership |
Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology
|
|
WO2001025481A1
(en)
*
|
1999-10-04 |
2001-04-12 |
Olympus Optical Co., Ltd. |
Method of detecting nucleic acid
|
|
JP4598338B2
(ja)
*
|
1999-10-04 |
2010-12-15 |
オリンパス株式会社 |
核酸検出方法
|
|
JP3668075B2
(ja)
|
1999-10-12 |
2005-07-06 |
光夫 板倉 |
遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたSNPs高速スコアリング方法
|
|
US7611869B2
(en)
|
2000-02-07 |
2009-11-03 |
Illumina, Inc. |
Multiplexed methylation detection methods
|
|
US7582420B2
(en)
|
2001-07-12 |
2009-09-01 |
Illumina, Inc. |
Multiplex nucleic acid reactions
|
|
US8076063B2
(en)
|
2000-02-07 |
2011-12-13 |
Illumina, Inc. |
Multiplexed methylation detection methods
|
|
US7955794B2
(en)
|
2000-09-21 |
2011-06-07 |
Illumina, Inc. |
Multiplex nucleic acid reactions
|
|
US9709559B2
(en)
|
2000-06-21 |
2017-07-18 |
Bioarray Solutions, Ltd. |
Multianalyte molecular analysis using application-specific random particle arrays
|
|
WO2004059289A2
(en)
|
2001-05-22 |
2004-07-15 |
Epicentre Technologies |
Target-dependent transcription using deletion mutants of n4 rna polymerase
|
|
US7291490B2
(en)
|
2001-06-11 |
2007-11-06 |
Ecopia Biosciences Inc. |
Nucleic acid fragment encoding an NRPS for the biosynthesis of anthramycin
|
|
CA2386587C
(en)
|
2001-06-11 |
2006-06-06 |
Ecopia Biosciences Inc. |
Genes and proteins for the biosynthesis of anthramycin
|
|
US7262063B2
(en)
|
2001-06-21 |
2007-08-28 |
Bio Array Solutions, Ltd. |
Directed assembly of functional heterostructures
|
|
KR20040068122A
(ko)
|
2001-10-15 |
2004-07-30 |
바이오어레이 솔루션스 리미티드 |
공동 검색과 효소-매개된 탐지에 의한 다형성 좌위의 다중분석
|
|
EP1860200A1
(de)
*
|
2001-12-03 |
2007-11-28 |
Illumina, Inc. |
Multiplexverfahren zur Methylierungsdetektion
|
|
AU2003275018B2
(en)
|
2002-09-20 |
2009-10-01 |
Integrated Dna Technologies, Inc. |
Anthraquinone quencher dyes, their methods of preparation and use
|
|
WO2004044242A1
(en)
*
|
2002-11-14 |
2004-05-27 |
John Nicholas Housby |
Polymorphism assay
|
|
AU2003298655A1
(en)
|
2002-11-15 |
2004-06-15 |
Bioarray Solutions, Ltd. |
Analysis, secure access to, and transmission of array images
|
|
US7595279B2
(en)
|
2003-09-22 |
2009-09-29 |
Bioarray Solutions Ltd. |
Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
|
|
EP1692298A4
(de)
|
2003-10-28 |
2008-08-13 |
Bioarray Solutions Ltd |
Optimierung der genexpressionsanalyse unter verwendung immobilisierter fängersonden
|
|
US7439341B2
(en)
|
2003-11-14 |
2008-10-21 |
Integrated Dna Technologies, Inc. |
Fluorescence quenching azo dyes, their methods of preparation and use
|
|
EP1718739B1
(de)
|
2004-02-04 |
2011-07-13 |
Novo Nordisk A/S |
Verfahren zur rückfaltung von säuger-glycosyltransferasen
|
|
US7848889B2
(en)
|
2004-08-02 |
2010-12-07 |
Bioarray Solutions, Ltd. |
Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
|
|
WO2006127507A2
(en)
|
2005-05-20 |
2006-11-30 |
Integrated Dna Technologies, Inc. |
Compounds and methods for labeling oligonucleotides
|
|
EP2172563A1
(de)
|
2008-09-24 |
2010-04-07 |
bioMérieux S.A. |
Verfahren zur Verringerung der Abhängigkeit von Sequenzvariationen eines Nukleinsäuretargets in einem diagnostischen Hybridisierungs-Assay
|
|
US9506057B2
(en)
|
2010-03-26 |
2016-11-29 |
Integrated Dna Technologies, Inc. |
Modifications for antisense compounds
|
|
AU2011230496B2
(en)
|
2010-03-26 |
2015-09-17 |
Integrated Dna Technologies, Inc. |
Methods for enhancing nucleic acid hybridization
|
|
CA2809457C
(en)
|
2010-09-07 |
2019-07-30 |
Integrated Dna Technologies, Inc. |
Modifications for antisense compounds
|
|
US20120107355A1
(en)
|
2010-10-27 |
2012-05-03 |
Harrisvaccines, Inc. |
Method of rapidly producing improved vaccines for animals
|
|
JP6243325B2
(ja)
|
2011-04-12 |
2017-12-06 |
ガンガゲン インコーポレーティッド |
キメラ抗菌ポリペプチド
|
|
EP2729580B1
(de)
|
2011-07-08 |
2015-09-16 |
Keygene N.V. |
Sequenzbasierte genotypisierung auf grundlage von oligonukleotid-verknüpfungsassays
|
|
CN105228648A
(zh)
|
2011-10-19 |
2016-01-06 |
哈里斯疫苗有限公司 |
快速产生改良的动物疫苗的方法
|
|
CN105264076B
(zh)
|
2013-01-28 |
2019-09-13 |
堪萨斯州立大学研究基金会 |
裂谷热病毒糖蛋白gn和gc及其用途
|
|
WO2015145463A1
(en)
|
2014-03-27 |
2015-10-01 |
Gangagen, Inc. |
Phage-derived compositions for improved mycobacterial therapy
|
|
JP7465418B2
(ja)
|
2017-12-14 |
2024-04-11 |
バクトクリア ホールディングス ピーティーイー エルティーディー. |
治療用バクテリオシン
|
|
CA3102892A1
(en)
|
2018-06-12 |
2019-12-19 |
Keygene N.V. |
Nucleic acid amplification method
|
|
CN113474466A
(zh)
|
2019-02-21 |
2021-10-01 |
主基因有限公司 |
多倍体基因分型
|
|
IL309032A
(en)
|
2021-06-03 |
2024-02-01 |
Mazen Animal Health Inc |
Oral administration of coronavirus spike protein to alter cytokine levels and provide passive immunity to newborn pigs
|