DK175739B1 - Saponinadjuvans - Google Patents

Saponinadjuvans Download PDF

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Publication number
DK175739B1
DK175739B1 DK198906029A DK602989A DK175739B1 DK 175739 B1 DK175739 B1 DK 175739B1 DK 198906029 A DK198906029 A DK 198906029A DK 602989 A DK602989 A DK 602989A DK 175739 B1 DK175739 B1 DK 175739B1
Authority
DK
Denmark
Prior art keywords
saponin
methanol
adjuvant
extract
antigen
Prior art date
Application number
DK198906029A
Other languages
Danish (da)
English (en)
Other versions
DK602989A (da
DK602989D0 (da
Inventor
Charlotte A Kensil
Dante J Marciani
Gerald A Beltz
Chung-Ho Hung
Original Assignee
Antigenics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21996520&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK175739(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Antigenics Inc filed Critical Antigenics Inc
Publication of DK602989A publication Critical patent/DK602989A/da
Publication of DK602989D0 publication Critical patent/DK602989D0/da
Application granted granted Critical
Publication of DK175739B1 publication Critical patent/DK175739B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005Glycosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/256Polyterpene radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
DK198906029A 1987-05-29 1989-11-29 Saponinadjuvans DK175739B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5522987A 1987-05-29 1987-05-29
US5522987 1987-05-29
US8801842 1988-05-31
PCT/US1988/001842 WO1988009336A1 (fr) 1987-05-29 1988-05-31 Adjuvant a base de saponine

Publications (3)

Publication Number Publication Date
DK602989A DK602989A (da) 1989-11-29
DK602989D0 DK602989D0 (da) 1989-11-29
DK175739B1 true DK175739B1 (da) 2005-02-07

Family

ID=21996520

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198906029A DK175739B1 (da) 1987-05-29 1989-11-29 Saponinadjuvans

Country Status (8)

Country Link
EP (1) EP0362279B2 (fr)
JP (1) JP2731563B2 (fr)
AT (1) ATE116993T1 (fr)
AU (1) AU616670B2 (fr)
CA (1) CA1331443C (fr)
DE (1) DE3852761T3 (fr)
DK (1) DK175739B1 (fr)
WO (1) WO1988009336A1 (fr)

Families Citing this family (155)

* Cited by examiner, † Cited by third party
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ATE116993T1 (de) 1995-01-15
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EP0362279B1 (fr) 1995-01-11
JP2731563B2 (ja) 1998-03-25
AU1934088A (en) 1988-12-21
DE3852761D1 (de) 1995-02-23
EP0362279B2 (fr) 1999-11-03
DE3852761T2 (de) 1995-09-07
DE3852761T3 (de) 2000-06-21
CA1331443C (fr) 1994-08-16
DK602989D0 (da) 1989-11-29
EP0362279A1 (fr) 1990-04-11
WO1988009336A1 (fr) 1988-12-01
AU616670B2 (en) 1991-11-07
JPH02504266A (ja) 1990-12-06

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