DK175683B1 - Fremgangsmåde til fremstilling af stabile sucralfatsuspensioner - Google Patents

Fremgangsmåde til fremstilling af stabile sucralfatsuspensioner Download PDF

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Publication number
DK175683B1
DK175683B1 DK198801984A DK198488A DK175683B1 DK 175683 B1 DK175683 B1 DK 175683B1 DK 198801984 A DK198801984 A DK 198801984A DK 198488 A DK198488 A DK 198488A DK 175683 B1 DK175683 B1 DK 175683B1
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DK
Denmark
Prior art keywords
sucralfate
suspension
gel
weight
solution
Prior art date
Application number
DK198801984A
Other languages
Danish (da)
English (en)
Other versions
DK198488A (da
DK198488D0 (da
Inventor
Ubaldo Conte
Paolo Colombo
Carla Caramella
Giorgio Zagnoli
Original Assignee
Lisapharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lisapharma Spa filed Critical Lisapharma Spa
Publication of DK198488D0 publication Critical patent/DK198488D0/da
Publication of DK198488A publication Critical patent/DK198488A/da
Application granted granted Critical
Publication of DK175683B1 publication Critical patent/DK175683B1/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Stereo-Broadcasting Methods (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Lift-Guide Devices, And Elevator Ropes And Cables (AREA)
  • Saccharide Compounds (AREA)
DK198801984A 1987-04-15 1988-04-12 Fremgangsmåde til fremstilling af stabile sucralfatsuspensioner DK175683B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20129/87A IT1203901B (it) 1987-04-15 1987-04-15 Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti
IT2012987 1987-04-15

Publications (3)

Publication Number Publication Date
DK198488D0 DK198488D0 (da) 1988-04-12
DK198488A DK198488A (da) 1988-10-17
DK175683B1 true DK175683B1 (da) 2005-01-17

Family

ID=11164041

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198801984A DK175683B1 (da) 1987-04-15 1988-04-12 Fremgangsmåde til fremstilling af stabile sucralfatsuspensioner

Country Status (20)

Country Link
US (1) US5321013A (fr)
EP (1) EP0286978B1 (fr)
JP (1) JPS6445312A (fr)
KR (1) KR930006037B1 (fr)
CN (1) CN1021629C (fr)
AT (1) ATE58144T1 (fr)
AU (1) AU623853B2 (fr)
CA (1) CA1306945C (fr)
DE (1) DE3860967D1 (fr)
DK (1) DK175683B1 (fr)
ES (1) ES2021781B3 (fr)
FI (1) FI88257C (fr)
GR (1) GR3002515T3 (fr)
IE (1) IE61339B1 (fr)
IN (1) IN169494B (fr)
IT (1) IT1203901B (fr)
MX (1) MX11135A (fr)
NO (1) NO174656C (fr)
NZ (1) NZ224253A (fr)
ZA (1) ZA882476B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2735559B2 (ja) * 1988-03-02 1998-04-02 中外製薬株式会社 懸濁液
IT1230157B (it) * 1989-06-16 1991-10-14 Lisapharma Spa Uso di sucralfato gel umido per il trattamento di ulcere del derma e come veicolo di farmaci ad attivita' topica
FR2657010B1 (fr) * 1990-01-12 1992-05-15 Pf Medicament Composition pharmaceutique sous forme de suspension aqueuse stable a base de sucrafalte et d'une substance anti-acide ainsi que son procede de preparation.
EP0549794B1 (fr) * 1990-08-31 2001-11-28 Chugai Seiyaku Kabushiki Kaisha Production d'une solution de base de sucralfate en suspension dans l'eau
DK86492D0 (da) * 1992-06-30 1992-06-30 Bukh Meditec Laegemiddel
IT1264546B1 (it) * 1993-07-30 1996-10-02 Lisapharma Spa Composizione farmaceutica ad attivita' antiacida in forma di sospensione a base di gel di sucralfato
BR9507533A (pt) * 1994-04-26 1997-09-02 Chugai Pharmaceutical Co Ltd Preparações de sucralfato granulado fundido e um processo para sua produção
IT1274735B (it) * 1994-08-25 1997-07-24 Enosys S P A Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco
IT1284030B1 (it) * 1996-06-18 1998-05-08 Solchem Italiana Spa Metodo per la produzione di sospensioni acquose stabili, utili nelle composizioni farmaceutiche
IT1301969B1 (it) * 1998-07-30 2000-07-20 Lisapharma Spa Sucralfato gel secco granulare e poroso procedimento per la suapreparazione, e composizioni farmaceutiche solide che lo contengono
US6391860B1 (en) * 1999-09-09 2002-05-21 Mcgrath Patrick D. Method for preparation and use of paste formed by controlled reaction of sucralfate with hydrochloric acid
CN100425244C (zh) * 2004-04-14 2008-10-15 中国人民解放军总医院 注射用硫酸铝,用于治疗膀胱肿瘤的注射用硫酸铝注射液
WO2010033408A1 (fr) * 2008-09-17 2010-03-25 Mcgrath Patrick D Procédés et compositions de pâte de sucralfate antimicrobienne
US10716802B2 (en) 2013-03-15 2020-07-21 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
GR1008308B (el) 2013-05-31 2014-10-02 UNI-PHARMA ΚΛΕΩΝ ΤΣΕΤΗΣ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "UNI-PHARMA ABEE", Τοπικες φαρμακευτικες και ιατροτεχνολογικες συνθεσεις που περιεχουν συνδυασμους σουκραλφατης, υαλουρονικου οξεος, αργινινης και ενος φυσικου ενυδατικου παραγοντα
JP6627485B2 (ja) * 2015-01-28 2020-01-08 ライオン株式会社 ゲル組成物及びその製造方法
JP6515680B2 (ja) * 2015-05-27 2019-05-22 ライオン株式会社 スクラルファート含有液状組成物
US10973846B2 (en) 2015-09-24 2021-04-13 The Brigham And Women's Hospital, Inc. Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
CN109431972B (zh) * 2018-11-20 2022-02-22 昆明积大制药股份有限公司 一种粒径为100nm—500nm的硫糖铝凝胶的成胶方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2512344A1 (fr) * 1981-09-08 1983-03-11 Af Aplicaciones Far Lab Procede de fabrication d'une suspension stable d'hydroxyde d'alumine et/ou d'hydroxyde de magnesie comme agent actif des antacida
JPS5978116A (ja) * 1982-10-27 1984-05-04 Chugai Pharmaceut Co Ltd スクラルフェ−ト製剤
DE3429263A1 (de) * 1984-08-08 1986-02-20 Gödecke AG, 1000 Berlin Verfahren zur stabilisierung filtrierbarer antacida mit hexitolen
DE3430809A1 (de) * 1984-08-22 1986-03-06 Merck Patent Gmbh, 6100 Darmstadt Sucralfat-suspension

Also Published As

Publication number Publication date
NZ224253A (en) 1991-03-26
FI88257B (fi) 1993-01-15
ATE58144T1 (de) 1990-11-15
JPH0576927B2 (fr) 1993-10-25
IT1203901B (it) 1989-02-23
AU623853B2 (en) 1992-05-28
NO881625D0 (no) 1988-04-14
DK198488A (da) 1988-10-17
CA1306945C (fr) 1992-09-01
AU1464388A (en) 1988-10-20
FI881769A (fi) 1988-10-16
IT8720129A0 (it) 1987-04-15
CN88102143A (zh) 1988-12-28
NO174656B (no) 1994-03-07
EP0286978B1 (fr) 1990-11-07
ES2021781B3 (es) 1991-11-16
CN1021629C (zh) 1993-07-21
EP0286978A1 (fr) 1988-10-19
IN169494B (fr) 1991-10-26
MX11135A (es) 1993-12-01
ZA882476B (en) 1988-09-29
IE61339B1 (en) 1994-11-02
NO881625L (no) 1988-10-17
DK198488D0 (da) 1988-04-12
GR3002515T3 (en) 1993-01-25
DE3860967D1 (de) 1990-12-13
FI88257C (fi) 1993-04-26
US5321013A (en) 1994-06-14
IE881038L (en) 1988-10-15
JPS6445312A (en) 1989-02-17
KR880012211A (ko) 1988-11-26
FI881769A0 (fi) 1988-04-15
KR930006037B1 (ko) 1993-07-03
NO174656C (no) 1994-06-15

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