DK175525B1 - Fremgangsmåde til fremstilling af fusionsproteiner, genstruktur, vektor indeholdende genstrukturen, streptomycetcelle indeholdende vektoren, fusionsprotein og anvendelse deraf - Google Patents
Fremgangsmåde til fremstilling af fusionsproteiner, genstruktur, vektor indeholdende genstrukturen, streptomycetcelle indeholdende vektoren, fusionsprotein og anvendelse deraf Download PDFInfo
- Publication number
- DK175525B1 DK175525B1 DK198802416A DK241688A DK175525B1 DK 175525 B1 DK175525 B1 DK 175525B1 DK 198802416 A DK198802416 A DK 198802416A DK 241688 A DK241688 A DK 241688A DK 175525 B1 DK175525 B1 DK 175525B1
- Authority
- DK
- Denmark
- Prior art keywords
- plasmid
- gene
- tendamistat
- vector
- fusion protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3714866 | 1987-05-05 | ||
| DE19873714866 DE3714866A1 (de) | 1987-05-05 | 1987-05-05 | Verfahren zur herstellung von fremdproteinen in streptomyceten |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK241688D0 DK241688D0 (da) | 1988-05-04 |
| DK241688A DK241688A (da) | 1988-11-06 |
| DK175525B1 true DK175525B1 (da) | 2004-11-22 |
Family
ID=6326841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198802416A DK175525B1 (da) | 1987-05-05 | 1988-05-04 | Fremgangsmåde til fremstilling af fusionsproteiner, genstruktur, vektor indeholdende genstrukturen, streptomycetcelle indeholdende vektoren, fusionsprotein og anvendelse deraf |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0289936B1 (no) |
| JP (1) | JP2671260B2 (no) |
| KR (1) | KR970001235B1 (no) |
| CN (1) | CN1029989C (no) |
| AR (1) | AR241658A1 (no) |
| AT (1) | ATE94905T1 (no) |
| AU (1) | AU612144B2 (no) |
| CA (1) | CA1338338C (no) |
| DE (2) | DE3714866A1 (no) |
| DK (1) | DK175525B1 (no) |
| ES (1) | ES2045004T3 (no) |
| FI (1) | FI97549C (no) |
| HU (1) | HU204094B (no) |
| IE (1) | IE62522B1 (no) |
| IL (1) | IL86277A0 (no) |
| NO (1) | NO178036C (no) |
| NZ (1) | NZ224464A (no) |
| PT (1) | PT87400B (no) |
| ZA (1) | ZA883168B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5426036A (en) * | 1987-05-05 | 1995-06-20 | Hoechst Aktiengesellschaft | Processes for the preparation of foreign proteins in streptomycetes |
| DE4012818A1 (de) | 1990-04-21 | 1991-10-24 | Hoechst Ag | Verfahren zur herstellung von fremdproteinen in streptomyceten |
| ES2081826T3 (es) * | 1988-11-03 | 1996-03-16 | Hoechst Ag | Procedimiento para la preparacion de un producto previo de insulina en estreptomicetos. |
| DE3844211A1 (de) * | 1988-12-29 | 1990-07-05 | Hoechst Ag | Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung |
| DE3936876A1 (de) * | 1989-11-06 | 1991-05-23 | Hoechst Ag | Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3331860A1 (de) * | 1983-09-03 | 1985-03-21 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von tendamistat |
| DE3418274A1 (de) * | 1984-05-17 | 1985-11-21 | Hoechst Ag, 6230 Frankfurt | Signalpeptid fuer die exkretion von peptiden in streptomyceten |
| ATE63757T1 (de) * | 1985-03-28 | 1991-06-15 | Chiron Corp | Expression durch verwendung von fusionsgenen fuer proteinproduktion. |
| DE3707150A1 (de) * | 1987-03-06 | 1988-09-15 | Hoechst Ag | Tendamistat-derivate |
| ES2081826T3 (es) * | 1988-11-03 | 1996-03-16 | Hoechst Ag | Procedimiento para la preparacion de un producto previo de insulina en estreptomicetos. |
-
1987
- 1987-05-05 DE DE19873714866 patent/DE3714866A1/de not_active Withdrawn
-
1988
- 1988-04-28 DE DE88106786T patent/DE3884261D1/de not_active Expired - Lifetime
- 1988-04-28 EP EP88106786A patent/EP0289936B1/de not_active Expired - Lifetime
- 1988-04-28 ES ES88106786T patent/ES2045004T3/es not_active Expired - Lifetime
- 1988-04-28 AT AT88106786T patent/ATE94905T1/de not_active IP Right Cessation
- 1988-05-03 NZ NZ224464A patent/NZ224464A/xx unknown
- 1988-05-03 FI FI882059A patent/FI97549C/fi not_active IP Right Cessation
- 1988-05-03 KR KR1019880005131A patent/KR970001235B1/ko not_active IP Right Cessation
- 1988-05-03 AR AR88310742A patent/AR241658A1/es active
- 1988-05-04 NO NO881942A patent/NO178036C/no unknown
- 1988-05-04 CA CA000565869A patent/CA1338338C/en not_active Expired - Lifetime
- 1988-05-04 ZA ZA883168A patent/ZA883168B/xx unknown
- 1988-05-04 DK DK198802416A patent/DK175525B1/da not_active IP Right Cessation
- 1988-05-04 PT PT87400A patent/PT87400B/pt not_active IP Right Cessation
- 1988-05-04 AU AU15559/88A patent/AU612144B2/en not_active Expired
- 1988-05-04 IE IE133888A patent/IE62522B1/en not_active IP Right Cessation
- 1988-05-04 CN CN88102568A patent/CN1029989C/zh not_active Expired - Lifetime
- 1988-05-04 HU HU882276A patent/HU204094B/hu unknown
- 1988-05-04 IL IL86277A patent/IL86277A0/xx not_active IP Right Cessation
- 1988-05-06 JP JP63110295A patent/JP2671260B2/ja not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |