DK175208B1 - Fremgangsmåde til fremstilling af et findelt fast stof - Google Patents

Fremgangsmåde til fremstilling af et findelt fast stof Download PDF

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Publication number
DK175208B1
DK175208B1 DK199100590A DK59091A DK175208B1 DK 175208 B1 DK175208 B1 DK 175208B1 DK 199100590 A DK199100590 A DK 199100590A DK 59091 A DK59091 A DK 59091A DK 175208 B1 DK175208 B1 DK 175208B1
Authority
DK
Denmark
Prior art keywords
solvent
solid
process according
liquid carrier
solution
Prior art date
Application number
DK199100590A
Other languages
Danish (da)
English (en)
Other versions
DK59091D0 (da
DK59091A (da
Inventor
William J Schmitt
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DK59091D0 publication Critical patent/DK59091D0/da
Publication of DK59091A publication Critical patent/DK59091A/da
Application granted granted Critical
Publication of DK175208B1 publication Critical patent/DK175208B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12—Powders or granules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/04—Specific aggregation state of one or more of the phases to be mixed
    • B01F23/043—Mixing fluids or with fluids in a supercritical state, in supercritical conditions or variable density fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/09—Mixing systems, i.e. flow charts or diagrams for components having more than two different of undetermined agglomeration states, e.g. supercritical states
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/48—Mixing liquids with liquids; Emulsifying characterised by the nature of the liquids
    • B01F23/481—Mixing liquids with liquids; Emulsifying characterised by the nature of the liquids using liquefied or cryogenic gases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0404—Technical information in relation with mixing theories or general explanations of phenomena associated with mixing or generalizations of a concept by comparison of equivalent methods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/21—Mixing gases with liquids by introducing liquids into gaseous media
DK199100590A 1988-10-05 1991-04-03 Fremgangsmåde til fremstilling af et findelt fast stof DK175208B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25384988A 1988-10-05 1988-10-05
US25384988 1988-10-05
US8903783 1989-09-06
PCT/US1989/003783 WO1990003782A2 (en) 1988-10-05 1989-09-06 Finely divided solid crystalline powders via precipitation into an anti-solvent

Publications (3)

Publication Number Publication Date
DK59091D0 DK59091D0 (da) 1991-04-03
DK59091A DK59091A (da) 1991-04-03
DK175208B1 true DK175208B1 (da) 2004-07-12

Family

ID=22961959

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199100590A DK175208B1 (da) 1988-10-05 1991-04-03 Fremgangsmåde til fremstilling af et findelt fast stof

Country Status (10)

Country Link
EP (1) EP0437451B1 (xx)
JP (1) JP2843857B2 (xx)
KR (1) KR0132576B1 (xx)
AU (1) AU624421B2 (xx)
CA (1) CA1338106C (xx)
DE (1) DE68907062T2 (xx)
DK (1) DK175208B1 (xx)
HK (1) HK89396A (xx)
HU (1) HU209603B (xx)
WO (1) WO1990003782A2 (xx)

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US5639441A (en) * 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
US5301664A (en) * 1992-03-06 1994-04-12 Sievers Robert E Methods and apparatus for drug delivery using supercritical solutions
US5389263A (en) * 1992-05-20 1995-02-14 Phasex Corporation Gas anti-solvent recrystallization and application for the separation and subsequent processing of RDX and HMX
JPH09508055A (ja) 1993-11-08 1997-08-19 ザ、ジレット、カンパニー 超臨界流体を用いる粒子の形成法、これによって形成されるエーロゲル粒子、およびエーロゲル粒子を含む制汗剤
IT1265473B1 (it) * 1993-12-30 1996-11-22 Otefal Srl Procedimento per la produzione di polveri a granulometria controllata e prodotto in polvere cosi' ottenuto
AT401871B (de) * 1994-01-28 1996-12-27 Gebro Broschek Gmbh Verfahren zur herstellung von s(+)-ibuprofen- partikeln mit verbesserten fliesseigenschaften und deren verwendung zur arzneimittelherstellung
GB9413202D0 (en) * 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
DE69618938T2 (de) * 1995-03-28 2002-10-31 Fidia Advanced Biopolymers Srl Nanosphären mit einem biokompatiblen polysaccharid
SE9501384D0 (sv) * 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
US5803966A (en) * 1995-11-01 1998-09-08 Alcon Laboratories, Inc. Process for sizing prednisolone acetate using a supercritical fluid anti-solvent
US5728315A (en) * 1996-05-01 1998-03-17 Alliedsignal Inc. Azeotrope-like compositions of trifluoromethane, carbon dioxide, ethane and hexafluoroethane
FR2753639B1 (fr) † 1996-09-25 1998-12-11 Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede
WO1998027072A1 (en) * 1996-12-17 1998-06-25 Cordant Technologies, Inc. Salting-out process of crystallizing 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.0?5,903,11¿]-dodecane
SE9701956D0 (sv) 1997-05-23 1997-05-23 Astra Ab New composition of matter
US6221153B1 (en) * 1998-06-09 2001-04-24 Trevor Percival Castor Method for producing large crystals of complex molecules
SE9804003D0 (sv) * 1998-11-23 1998-11-23 Astra Ab A method of producing drug particles
GB9828721D0 (en) * 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
SE9901667D0 (sv) 1999-05-07 1999-05-07 Astra Ab Method and device for forming particles
GB9915975D0 (en) 1999-07-07 1999-09-08 Bradford Particle Design Ltd Method for the formation of particles
PL202704B1 (pl) 2000-03-03 2009-07-31 Boehringer Ingelheim Pharma Sposób obróbki substancji rozpuszczanej, sposób jej krystalizacji z roztworu, sposób jej ekstrakcji z mieszaniny, sposób powlekania substancją substratu, sposób nasycania nośnika substancją, sposób usuwania zanieczyszczeń z wyrobu, oraz sposób przeprowadzania reakcji chemicznych w celu wytworzenia produktu reakcji
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US6620351B2 (en) 2000-05-24 2003-09-16 Auburn University Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer
ES2170008B1 (es) * 2000-08-25 2003-05-01 Soc Es Carburos Metalicos Sa Procedimiento para la precipitacion de particulas solidas finamente divididas.
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US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
DE10105801B4 (de) 2001-02-07 2004-07-08 Henkel Kgaa Wasch- und Reinigungsmittel umfassend feine Mikropartikel mit Reinigungsmittelbestandteilen
US7276184B2 (en) 2001-07-12 2007-10-02 Eastman Kodak Company Surfactant assisted nanomaterial generation process
GB0117696D0 (en) 2001-07-20 2001-09-12 Bradford Particle Design Plc Particle information
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
EP1429749A2 (en) 2001-09-26 2004-06-23 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
ATE418347T1 (de) 2002-02-19 2009-01-15 Resolution Chemicals Ltd Auf lösungsmitteln basierende sterilisation von steroiden
DE10218107A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen von Steroiden, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
MY143936A (en) 2003-03-27 2011-07-29 Nycomed Gmbh Process for preparing crystalline ciclesonide with defined particle size
CA2524773C (en) 2003-05-08 2014-04-08 Nektar Therapeutics Uk Ltd Particulate coformulations of active substances with excipients
CN1819863A (zh) * 2003-06-10 2006-08-16 大正制药株式会社 放射形球状晶析物及其制造方法以及使用它的干粉制剂
NZ545146A (en) 2006-02-07 2009-03-31 Ind Res Ltd Near-critical fluid fractionation process for extracting plant or animal material
CA2647809C (en) 2006-03-24 2016-08-16 Auxilium Pharmaceuticals, Inc. Stabilized compositions containing alkaline labile drugs
JP5173842B2 (ja) * 2007-01-31 2013-04-03 富山化学工業株式会社 ピペラシリンナトリウムの新規な結晶
EP2425820B1 (en) 2007-02-11 2015-04-08 MAP Pharmaceuticals Inc Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
EP2156823A1 (en) * 2008-08-14 2010-02-24 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmeceutical compounds in the form of micro and nanoparticles
US8071656B2 (en) 2009-03-03 2011-12-06 Dynasep Llc Nylon extraction from commingled materials
WO2011015226A1 (en) * 2009-08-03 2011-02-10 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmaceutical compounds in the form of micro and nanoparticles
CA2767773C (en) 2011-02-11 2015-11-24 Grain Processing Corporation Composition comprising a salt and a crystallization interrupter
CA2897670C (en) * 2013-01-07 2021-04-06 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US8778181B1 (en) * 2013-03-14 2014-07-15 Crititech, Inc. Equipment assembly for and method of processing particles
EP4275692A2 (en) * 2021-01-08 2023-11-15 Seoul National University R & DB Foundation Dried-cell-secretome-based therapeutic agent for treating osteoarthritis

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GB899667A (en) * 1960-04-19 1962-06-27 Glaxo Lab Ltd Crystalline griseofulvin
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
FR2608988B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules

Also Published As

Publication number Publication date
WO1990003782A2 (en) 1990-04-19
DK59091D0 (da) 1991-04-03
KR0132576B1 (ko) 1998-04-17
JPH04500925A (ja) 1992-02-20
DE68907062T2 (de) 1993-10-07
AU624421B2 (en) 1992-06-11
WO1990003782A3 (en) 1990-07-26
HK89396A (en) 1996-05-31
HUT56265A (en) 1991-08-28
EP0437451A1 (en) 1991-07-24
EP0437451B1 (en) 1993-06-09
HU209603B (en) 1994-09-28
KR900701253A (ko) 1990-12-01
HU895780D0 (en) 1991-07-29
AU4219889A (en) 1990-05-01
DE68907062D1 (de) 1993-07-15
CA1338106C (en) 1996-03-05
DK59091A (da) 1991-04-03
JP2843857B2 (ja) 1999-01-06

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