GB899667A - Crystalline griseofulvin - Google Patents
Crystalline griseofulvinInfo
- Publication number
- GB899667A GB899667A GB1372460A GB1372460A GB899667A GB 899667 A GB899667 A GB 899667A GB 1372460 A GB1372460 A GB 1372460A GB 1372460 A GB1372460 A GB 1372460A GB 899667 A GB899667 A GB 899667A
- Authority
- GB
- United Kingdom
- Prior art keywords
- griseofulvin
- solvent
- crystalline
- admixing
- acetone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
Landscapes
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Crystalline griseofulvin is produced by admixing a solution of griseofulvin in a griseofulvin solvent such as acetone, methanol, ethanol, dimethyl formamide or dimethyl acetamide with a griseofulvin non-solvent which is at least partially miscible with the griseofulvin solvent such as water, by pouring one liquid into the other which is being vigourously and non-vertically stirred. Specification 899,668 is referred to.ALSO:Crystalline griseofulvin is produced by admixing a solution of griseofulvin in a griseofulvin solvent such as acetone, methanol, ethanol, dimethyl formamide or dimethyl acetamide with a griseofulvin non-solvent which is at least partially miscible with the griseofulvin solvent, such as water, under such conditions as to effect rapidly substantially complete intermixing of the liquids on and after contact. Specification 899,668 is referred to.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1372460A GB899667A (en) | 1960-04-19 | 1960-04-19 | Crystalline griseofulvin |
BR12849161A BR6128491D0 (en) | 1960-04-19 | 1961-04-18 | PROCESS FOR THE PRODUCTION OF CRYSTALLINE GRISEOFULVINE |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1372460A GB899667A (en) | 1960-04-19 | 1960-04-19 | Crystalline griseofulvin |
Publications (1)
Publication Number | Publication Date |
---|---|
GB899667A true GB899667A (en) | 1962-06-27 |
Family
ID=10028228
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1372460A Expired GB899667A (en) | 1960-04-19 | 1960-04-19 | Crystalline griseofulvin |
Country Status (2)
Country | Link |
---|---|
BR (1) | BR6128491D0 (en) |
GB (1) | GB899667A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990003782A2 (en) * | 1988-10-05 | 1990-04-19 | The Upjohn Company | Finely divided solid crystalline powders via precipitation into an anti-solvent |
EP0544657A1 (en) * | 1984-05-21 | 1993-06-09 | The University Of Rochester | Method for making uniformly-sized particles from insoluble compounds |
EP1603652A2 (en) * | 2003-03-04 | 2005-12-14 | Five Star Technologies, Inc. | Hydrodynamic cavitation crystallization device and process |
CN116655571A (en) * | 2023-05-16 | 2023-08-29 | 天津大学 | Preparation method of griseofulvin superfine crystals |
-
1960
- 1960-04-19 GB GB1372460A patent/GB899667A/en not_active Expired
-
1961
- 1961-04-18 BR BR12849161A patent/BR6128491D0/en unknown
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0544657A1 (en) * | 1984-05-21 | 1993-06-09 | The University Of Rochester | Method for making uniformly-sized particles from insoluble compounds |
EP0544657A4 (en) * | 1984-05-21 | 1993-08-04 | The University Of Rochester | Method for making uniformly-sized particles from insoluble compounds |
WO1990003782A2 (en) * | 1988-10-05 | 1990-04-19 | The Upjohn Company | Finely divided solid crystalline powders via precipitation into an anti-solvent |
WO1990003782A3 (en) * | 1988-10-05 | 1990-07-26 | Upjohn Co | Finely divided solid crystalline powders via precipitation into an anti-solvent |
EP1603652A2 (en) * | 2003-03-04 | 2005-12-14 | Five Star Technologies, Inc. | Hydrodynamic cavitation crystallization device and process |
EP1603652A4 (en) * | 2003-03-04 | 2006-08-09 | Five Star Technologies Inc | Hydrodynamic cavitation crystallization device and process |
CN116655571A (en) * | 2023-05-16 | 2023-08-29 | 天津大学 | Preparation method of griseofulvin superfine crystals |
Also Published As
Publication number | Publication date |
---|---|
BR6128491D0 (en) | 1973-06-07 |
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