GB899667A - Crystalline griseofulvin - Google Patents

Crystalline griseofulvin

Info

Publication number
GB899667A
GB899667A GB1372460A GB1372460A GB899667A GB 899667 A GB899667 A GB 899667A GB 1372460 A GB1372460 A GB 1372460A GB 1372460 A GB1372460 A GB 1372460A GB 899667 A GB899667 A GB 899667A
Authority
GB
United Kingdom
Prior art keywords
griseofulvin
solvent
crystalline
admixing
acetone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1372460A
Inventor
George Shaw
Alan Newby Boyd
Dennis Bayliff
Malcolm David Shepherd
Frank William Anderson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Priority to GB1372460A priority Critical patent/GB899667A/en
Priority to BR12849161A priority patent/BR6128491D0/en
Publication of GB899667A publication Critical patent/GB899667A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Crystalline griseofulvin is produced by admixing a solution of griseofulvin in a griseofulvin solvent such as acetone, methanol, ethanol, dimethyl formamide or dimethyl acetamide with a griseofulvin non-solvent which is at least partially miscible with the griseofulvin solvent such as water, by pouring one liquid into the other which is being vigourously and non-vertically stirred. Specification 899,668 is referred to.ALSO:Crystalline griseofulvin is produced by admixing a solution of griseofulvin in a griseofulvin solvent such as acetone, methanol, ethanol, dimethyl formamide or dimethyl acetamide with a griseofulvin non-solvent which is at least partially miscible with the griseofulvin solvent, such as water, under such conditions as to effect rapidly substantially complete intermixing of the liquids on and after contact. Specification 899,668 is referred to.
GB1372460A 1960-04-19 1960-04-19 Crystalline griseofulvin Expired GB899667A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB1372460A GB899667A (en) 1960-04-19 1960-04-19 Crystalline griseofulvin
BR12849161A BR6128491D0 (en) 1960-04-19 1961-04-18 PROCESS FOR THE PRODUCTION OF CRYSTALLINE GRISEOFULVINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1372460A GB899667A (en) 1960-04-19 1960-04-19 Crystalline griseofulvin

Publications (1)

Publication Number Publication Date
GB899667A true GB899667A (en) 1962-06-27

Family

ID=10028228

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1372460A Expired GB899667A (en) 1960-04-19 1960-04-19 Crystalline griseofulvin

Country Status (2)

Country Link
BR (1) BR6128491D0 (en)
GB (1) GB899667A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003782A2 (en) * 1988-10-05 1990-04-19 The Upjohn Company Finely divided solid crystalline powders via precipitation into an anti-solvent
EP0544657A1 (en) * 1984-05-21 1993-06-09 The University Of Rochester Method for making uniformly-sized particles from insoluble compounds
EP1603652A2 (en) * 2003-03-04 2005-12-14 Five Star Technologies, Inc. Hydrodynamic cavitation crystallization device and process
CN116655571A (en) * 2023-05-16 2023-08-29 天津大学 Preparation method of griseofulvin superfine crystals

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0544657A1 (en) * 1984-05-21 1993-06-09 The University Of Rochester Method for making uniformly-sized particles from insoluble compounds
EP0544657A4 (en) * 1984-05-21 1993-08-04 The University Of Rochester Method for making uniformly-sized particles from insoluble compounds
WO1990003782A2 (en) * 1988-10-05 1990-04-19 The Upjohn Company Finely divided solid crystalline powders via precipitation into an anti-solvent
WO1990003782A3 (en) * 1988-10-05 1990-07-26 Upjohn Co Finely divided solid crystalline powders via precipitation into an anti-solvent
EP1603652A2 (en) * 2003-03-04 2005-12-14 Five Star Technologies, Inc. Hydrodynamic cavitation crystallization device and process
EP1603652A4 (en) * 2003-03-04 2006-08-09 Five Star Technologies Inc Hydrodynamic cavitation crystallization device and process
CN116655571A (en) * 2023-05-16 2023-08-29 天津大学 Preparation method of griseofulvin superfine crystals

Also Published As

Publication number Publication date
BR6128491D0 (en) 1973-06-07

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