ATE418347T1 - Auf lösungsmitteln basierende sterilisation von steroiden - Google Patents

Auf lösungsmitteln basierende sterilisation von steroiden

Info

Publication number
ATE418347T1
ATE418347T1 AT03742601T AT03742601T ATE418347T1 AT E418347 T1 ATE418347 T1 AT E418347T1 AT 03742601 T AT03742601 T AT 03742601T AT 03742601 T AT03742601 T AT 03742601T AT E418347 T1 ATE418347 T1 AT E418347T1
Authority
AT
Austria
Prior art keywords
solvent
steroids
sterile
pharmaceutical compound
based sterilization
Prior art date
Application number
AT03742601T
Other languages
English (en)
Inventor
Parveen Bhatarah
Alan Greenwood
Original Assignee
Resolution Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0203912A external-priority patent/GB0203912D0/en
Application filed by Resolution Chemicals Ltd filed Critical Resolution Chemicals Ltd
Application granted granted Critical
Publication of ATE418347T1 publication Critical patent/ATE418347T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
AT03742601T 2002-02-19 2003-02-19 Auf lösungsmitteln basierende sterilisation von steroiden ATE418347T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0203912A GB0203912D0 (en) 2002-02-19 2002-02-19 Solvent-based sterilisation of pharmaceuticals
GB0218724A GB0218724D0 (en) 2002-02-19 2002-08-12 Solvent-based sterilisation o pharmaceuticals

Publications (1)

Publication Number Publication Date
ATE418347T1 true ATE418347T1 (de) 2009-01-15

Family

ID=27758830

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03742601T ATE418347T1 (de) 2002-02-19 2003-02-19 Auf lösungsmitteln basierende sterilisation von steroiden

Country Status (9)

Country Link
US (2) US8541399B2 (de)
EP (1) EP1476201B1 (de)
AT (1) ATE418347T1 (de)
AU (1) AU2003246829A1 (de)
DE (1) DE60325459D1 (de)
DK (1) DK1476201T3 (de)
ES (1) ES2318145T3 (de)
SI (1) SI1476201T1 (de)
WO (1) WO2003070285A1 (de)

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SE9704186D0 (sv) 1997-11-14 1997-11-14 Astra Ab New composition of matter
ITMI20022674A1 (it) * 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
DE10306761B9 (de) * 2003-02-17 2004-12-23 Völkl, Klaus Peter, Dr. Verfahren zur Herstellung von sterilen pharmazeutischen Wirkstoffen
GB0319500D0 (en) 2003-08-19 2003-09-17 Resolution Chemicals Ltd Particle-size reduction apparatus,and use thereof
ITMI20032054A1 (it) 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
WO2006000913A1 (en) * 2004-06-23 2006-01-05 Pfizer Products Inc. Method for sterile filtration of viscous pharmaceutical compositions
GB0427568D0 (en) 2004-12-16 2005-01-19 Resolution Chemicals Ltd Particle-size reduction apparatus, and the use thereof
ATE552032T1 (de) 2005-07-14 2012-04-15 Lithera Inc Verbesserte lipolytikum-formulierung mit hinhaltender wirkstofffreigabe für die arealbehandlung von fettgewebe
GB0604141D0 (en) * 2006-03-01 2006-04-12 Arrow Int Ltd Nebulizer formulation
FR2898273B1 (fr) * 2006-03-07 2013-11-08 Merck Generiques Procede de sterilisation par chauffage par voie seche d'une poudre comprenant un glucocorticosteroide
GB2443287B (en) * 2006-10-17 2009-05-27 Lipothera Inc Methods, compositions and formulations for the treatment of thyroid eye disease
JP2011504381A (ja) * 2007-11-01 2011-02-10 ヤンセン ファーマシューティカ エヌ．ベー． 薬剤供給パッケージ
US9132084B2 (en) 2009-05-27 2015-09-15 Neothetics, Inc. Methods for administration and formulations for the treatment of regional adipose tissue
EP2523667A4 (de) * 2010-01-15 2014-04-02 Lithera Inc Lyophilisierte kuchenformulierungen
MX2013005873A (es) 2010-11-24 2013-08-07 Lithera Inc Formulaciones monoterapeuticas de agonistas beta selectivo, lipofilo y de accion prolongada y procedimientos para el tratamiento cosmetico de adiposidad y abultamiento del contorno.
ES2727474T3 (es) 2012-05-08 2019-10-16 Nicox Ophthalmics Inc Nanocristales de propionato de fluticasona
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
IN2014CH01890A (de) * 2014-04-10 2015-10-16 Aurobindo Pharma Ltd

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US3962430A (en) 1974-08-07 1976-06-08 Merck & Co., Inc. Sterilization of solid non-electrolyte medicinal agents employing sodium chloride
DE2837115A1 (de) 1978-08-25 1980-03-06 Bayer Ag Neues verfahren zur herstellung von sterilen feststoffen
JPS5732212A (en) * 1980-08-07 1982-02-20 Mitsui Toatsu Chem Inc Sterilizing method of acetylsalicylate salt
US4695454A (en) * 1985-04-01 1987-09-22 New York Blood Center, Inc. Process for preparing hepatitis B surface antigen containing particles in novel forms which are highly immunogenic
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JPH0660106B2 (ja) * 1985-11-14 1994-08-10 徳男 斎藤 生薬類を主剤とする滅菌丸剤の製造法
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DE3834371A1 (de) * 1988-10-10 1990-04-12 Gustmann Westphahlen Hartmut Verfahren zur sterilisierung von teilchenfoermigen pharmazeutischen substanzen
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US5958378A (en) * 1996-07-03 1999-09-28 Research Development Foundation High dose liposomal aerosol formulations containing cyclosporin A or budesonide
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Also Published As

Publication number Publication date
US20050222108A1 (en) 2005-10-06
DK1476201T3 (da) 2009-03-30
WO2003070285A1 (en) 2003-08-28
US8541399B2 (en) 2013-09-24
EP1476201A1 (de) 2004-11-17
EP1476201B1 (de) 2008-12-24
ES2318145T3 (es) 2009-05-01
US20100197646A1 (en) 2010-08-05
SI1476201T1 (sl) 2009-06-30
AU2003246829A1 (en) 2003-09-09
DE60325459D1 (de) 2009-02-05

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