JPS5732212A - Sterilizing method of acetylsalicylate salt - Google Patents

Sterilizing method of acetylsalicylate salt

Info

Publication number
JPS5732212A
JPS5732212A JP10766680A JP10766680A JPS5732212A JP S5732212 A JPS5732212 A JP S5732212A JP 10766680 A JP10766680 A JP 10766680A JP 10766680 A JP10766680 A JP 10766680A JP S5732212 A JPS5732212 A JP S5732212A
Authority
JP
Japan
Prior art keywords
amino acid
concentration
salt
acid salt
lysine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10766680A
Other languages
Japanese (ja)
Inventor
Yoshitsugu Yamada
Toshimitsu Okuma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP10766680A priority Critical patent/JPS5732212A/en
Publication of JPS5732212A publication Critical patent/JPS5732212A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain a sterile product suitable for a medicine readily, by immersing an amino acid salt of acetylsalicylic acid which is unsuitable in the sterility test in ethanol or propanol of a specific concentration at a specified temperature, and separating the amino acid salt.
CONSTITUTION: An amino acid salt of acethylsalicylic acid, e.g. a salt of dl-lysine, l-lysine, dl-arginine or dl-histidine, is immersed in ethyl alcohol, n- or iso-propyl alcohol in a concentration of 70W95wt% at 10W30°C, and if necessary stirred for 1W5hr. The formed crystals are then filtered, washed with the alcohol of the concentration and dried to give the aimed sterile product. The drying operation is preferably carried out at a temperature as low as possible under reduced pressure.
COPYRIGHT: (C)1982,JPO&Japio
JP10766680A 1980-08-07 1980-08-07 Sterilizing method of acetylsalicylate salt Pending JPS5732212A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10766680A JPS5732212A (en) 1980-08-07 1980-08-07 Sterilizing method of acetylsalicylate salt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10766680A JPS5732212A (en) 1980-08-07 1980-08-07 Sterilizing method of acetylsalicylate salt

Publications (1)

Publication Number Publication Date
JPS5732212A true JPS5732212A (en) 1982-02-20

Family

ID=14464920

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10766680A Pending JPS5732212A (en) 1980-08-07 1980-08-07 Sterilizing method of acetylsalicylate salt

Country Status (1)

Country Link
JP (1) JPS5732212A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002503211A (en) * 1996-06-27 2002-01-29 ザ、プロクター、エンド、ギャンブル、カンパニー Cosmetic composition
WO2003070285A1 (en) * 2002-02-19 2003-08-28 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals
DE10306761B3 (en) * 2003-02-17 2004-08-26 Völkl, Klaus Peter, Dr. Process for the production of sterile active pharmaceutical ingredients
US7524834B2 (en) 1997-11-14 2009-04-28 Astrazeneca Ab Sterile powders, formulations, and methods for producing the same
CN102993036A (en) * 2011-09-10 2013-03-27 海南中化联合制药工业股份有限公司 Preparation method of aspirin-DL-lysine sterile raw material

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002503211A (en) * 1996-06-27 2002-01-29 ザ、プロクター、エンド、ギャンブル、カンパニー Cosmetic composition
US7524834B2 (en) 1997-11-14 2009-04-28 Astrazeneca Ab Sterile powders, formulations, and methods for producing the same
WO2003070285A1 (en) * 2002-02-19 2003-08-28 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals
US8541399B2 (en) 2002-02-19 2013-09-24 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals
DE10306761B3 (en) * 2003-02-17 2004-08-26 Völkl, Klaus Peter, Dr. Process for the production of sterile active pharmaceutical ingredients
DE10306761B9 (en) * 2003-02-17 2004-12-23 Völkl, Klaus Peter, Dr. Process for the production of sterile active pharmaceutical ingredients
CN102993036A (en) * 2011-09-10 2013-03-27 海南中化联合制药工业股份有限公司 Preparation method of aspirin-DL-lysine sterile raw material

Similar Documents

Publication Publication Date Title
Harfenist et al. Countercurrent distribution studies with insulin
Casey et al. Disulfide stereochemistry. Conformations and chiroptical properties of L-cystine derivatives
JPS5732212A (en) Sterilizing method of acetylsalicylate salt
JPS5753446A (en) Peptide derivative
JPS5223020A (en) Process for preparation of fluorocompound containing oxygen
JPS55148098A (en) Concentration and purification of interferon
Shive et al. Growth inhibition by analogues of pantothenic acid. II. α-and β-substituted pantothenic acids and related compounds
JPS53109554A (en) Crystallization of proteins
JPS5446701A (en) Purification of carbolylic acid esters
JPS57128663A (en) Preparation of purified sodium glutamate crystal
JPS5223037A (en) Process for preparation of optical active amino acid
ES483076A1 (en) Process for the purification of tryptophane and derivatives of tryptophane
JPS5239622A (en) Process for preparation of methacrylic acid
JPS57150382A (en) Purification of super oxide dismutase
SU1681922A1 (en) Method of separating acid admixtures from hydrogen
JPS5315486A (en) Mass-screening analysis for individual amino acids
JPS57188563A (en) Preparation of optically active 3-benzoylthio-2-methyl- propionic acid
FR2304388A1 (en) PROCESS FOR THE ELIMINATION OF HYDROFLUORIC ACID FROM GAS CURRENTS IN CONTAINER
JPS553A (en) Production of 2-amino-3-butynoic acid
JPS5225726A (en) Process for preparation of omega-aminoalkanoic acid arylamides
Nelson et al. Improved analysis of citrate and aconitate in plant tissues
JPS5239852A (en) Heat exchange plant
FR2351097A1 (en) PROCESS FOR THE PREPARATION OF P-TOLUENE-SULPHONIC ACID, ISOMER FREE
JPS55130979A (en) Production of phaeophytic acid
JPS57131225A (en) Purification of polycarbonate solution