ATE184884T1 - Fibrinogenkonzentrate aus blutplasma, verfahren und anlage für ihre herstellung - Google Patents

Fibrinogenkonzentrate aus blutplasma, verfahren und anlage für ihre herstellung

Info

Publication number
ATE184884T1
ATE184884T1 AT95927599T AT95927599T ATE184884T1 AT E184884 T1 ATE184884 T1 AT E184884T1 AT 95927599 T AT95927599 T AT 95927599T AT 95927599 T AT95927599 T AT 95927599T AT E184884 T1 ATE184884 T1 AT E184884T1
Authority
AT
Austria
Prior art keywords
pct
fibrinogen
fibrinogen concentrate
production
viral
Prior art date
Application number
AT95927599T
Other languages
English (en)
Inventor
Ruth Laub
Wael Luc De
Original Assignee
Croix Rouge De Belgique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8218658&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE184884(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Croix Rouge De Belgique filed Critical Croix Rouge De Belgique
Application granted granted Critical
Publication of ATE184884T1 publication Critical patent/ATE184884T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0042—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Materials Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
AT95927599T 1994-07-14 1995-07-14 Fibrinogenkonzentrate aus blutplasma, verfahren und anlage für ihre herstellung ATE184884T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94870121 1994-07-14

Publications (1)

Publication Number Publication Date
ATE184884T1 true ATE184884T1 (de) 1999-10-15

Family

ID=8218658

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95927599T ATE184884T1 (de) 1994-07-14 1995-07-14 Fibrinogenkonzentrate aus blutplasma, verfahren und anlage für ihre herstellung

Country Status (9)

Country Link
US (1) US5834420A (de)
EP (1) EP0771324B2 (de)
JP (1) JP4211894B2 (de)
AT (1) ATE184884T1 (de)
CA (1) CA2195127C (de)
DE (1) DE69512416T3 (de)
ES (1) ES2139227T5 (de)
IL (1) IL122665A (de)
WO (1) WO1996002571A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2139227T5 (es) * 1994-07-14 2011-05-04 Caf-Dcf Département Central De Fractionnement De La Croix Rouge S.C.R.L. Concentrado de fibrinógeno obtenido de plasma sanguíneo, procedimiento e instalación para su preparación.
DE69637181T2 (de) 1995-07-14 2008-04-17 Caf - Dcf Cvba - Scrl Vorrichtung zur inaktivierung von viralen verunreinigungen in blutprodukten
AU6104799A (en) * 1998-09-24 2000-04-10 Ppl Therapeutics (Scotland) Limited Purification of fibrinogen from fluids by precipitation and hydrophoic chromatography
DE69930653T2 (de) 1998-09-24 2007-01-25 Pharming Intellectual Property Bv Reinigung von fibrinogen aus milch durch den einsatz von kationenaustauschchromatographie
FR2785206B1 (fr) * 1998-10-14 2001-01-19 Fond Jean Dausset Ceph Dispositif de centrifugation pour automate de laboratoire
US6946140B1 (en) * 1999-02-09 2005-09-20 The Research Foundation Of State University Of New York Methods and compositions for enhancing fibroblast migration
CA2394797A1 (en) * 1999-12-20 2001-06-28 Tsuyoshi Takahashi Process for producing virus-free plasma protein composition by porous membrane treatment, virus-free plasma protein composition and method of removing viruses
NZ518692A (en) * 1999-12-23 2004-08-27 Csl Ltd Purified fibrinogen free of destabilising levels of plasminogen and other proteases obtained from a Fraction I paste
US20030086817A1 (en) * 2001-11-06 2003-05-08 Horton Isaac B. Blood purification system
DK1476201T3 (da) 2002-02-19 2009-03-30 Resolution Chemicals Ltd Solvent-baseret sterilisering af steroider
EP1596888B1 (de) 2003-02-27 2012-01-11 Baxter International Inc. Verfahren für die überprüfbare inaktivierung von pathogenen in einem biologischen fluid durch bestrahlung
US20050124038A1 (en) * 2003-07-14 2005-06-09 Pharmacia Corporation Transfection of cartilage and matrices thereof in vitro
EP2335650B1 (de) 2003-12-11 2012-10-03 Isto Technologies Inc. Teilchenförmiges Knorpelsystem
EP1753860B1 (de) * 2004-02-20 2012-04-11 Isto Technologies Inc. Bandscheibenreparatur und verfahren dafür
DE102004009400A1 (de) * 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
JP5112060B2 (ja) * 2004-06-29 2013-01-09 リライアンス ライフ サイエンシーズ プライベイト リミテッド ウイルス安全性生物学的流体の調製のための方法
FR2887883B1 (fr) * 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
WO2009118331A1 (en) * 2008-03-28 2009-10-01 Research Foundation For Medical Devices Method of viral inactivation of biological fluids by solvent/detergent-treatment
CN103328503B (zh) 2010-09-20 2016-08-24 欧克塔医药公司 纤维蛋白原生产方法
US20140287044A1 (en) * 2011-03-04 2014-09-25 Rare Antibody Antigen Supply, Inc. Fibrin sealant (fibringluraas) consisting of a kit of lyophilized or frozen high concentrate fribinogen
WO2013135684A1 (en) * 2012-03-13 2013-09-19 Octapharma Ag Improved process for production of fibrinogen and fibrinogen produced thereby
CH706420A1 (fr) * 2012-04-19 2013-10-31 Valerie Soulie Procédé d'inactivation virale d'un fluide biologique, dispositif et récipient pour la mise en œuvre d'un tel procédé.
US20140154233A1 (en) * 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
IL231230A0 (en) 2014-02-27 2014-08-31 Omrix Biopharmaceuticals Ltd Fibrinogen preparation
US9932388B2 (en) 2014-11-13 2018-04-03 Hemarus Therapeutics Limited Chromatographic process for producing high purity fibrinogen and thrombin
JP2023505842A (ja) * 2019-12-10 2023-02-13 ビオテスト・アクチエンゲゼルシャフト フィブリノゲン製剤の製造方法
CN111518197B (zh) * 2020-03-30 2024-01-05 哈尔滨派斯菲科生物制药有限公司 一种纤维蛋白原的生产方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5598196A (en) * 1979-01-16 1980-07-25 Meito Sangyo Kk Fractionation of fibrinogen or its constituents and their use
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
US4481189A (en) † 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
GB8505882D0 (en) * 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii
DE3734923C1 (de) * 1987-10-15 1989-01-26 Biotest Pharma Gmbh Verfahren zur Herstellung einer sterilen Plasmaproteinloesung,die Fibrinogen und den Gerinnungsfaktor XIII enthaelt
FR2632309B1 (fr) † 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
EP0378208B2 (de) † 1989-01-13 2003-01-15 Mitsubishi Pharma Corporation Verfahren zur Herstellung einer Protein enthaltenden Zusammensetzung
WO1993005067A1 (en) * 1991-09-05 1993-03-18 Baxter International, Inc. Topical fibrinogen complex
FR2686883B1 (fr) * 1992-02-04 1994-05-13 Aquitaine Develop Transf Sanguin Procede de fabrication de fibrinogene de tres haute purete, fibrinogene de tres haute purete obtenu ainsi qu'une composition pharmaceutique le contenant.
ES2139227T5 (es) * 1994-07-14 2011-05-04 Caf-Dcf Département Central De Fractionnement De La Croix Rouge S.C.R.L. Concentrado de fibrinógeno obtenido de plasma sanguíneo, procedimiento e instalación para su preparación.

Also Published As

Publication number Publication date
EP0771324A1 (de) 1997-05-07
IL122665A (en) 2001-08-26
JPH10506607A (ja) 1998-06-30
ES2139227T5 (es) 2011-05-04
DE69512416T2 (de) 2000-02-17
ES2139227T3 (es) 2000-02-01
IL122665A0 (en) 1998-08-16
DE69512416T3 (de) 2011-12-15
CA2195127C (en) 2007-06-19
EP0771324B1 (de) 1999-09-22
CA2195127A1 (en) 1996-02-01
EP0771324B2 (de) 2011-02-09
JP4211894B2 (ja) 2009-01-21
DE69512416D1 (de) 1999-10-28
US5834420A (en) 1998-11-10
WO1996002571A1 (fr) 1996-02-01

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