IL122665A - Method and apparatus for inactivating contaminants in blood products - Google Patents

Method and apparatus for inactivating contaminants in blood products

Info

Publication number
IL122665A
IL122665A IL12266596A IL12266596A IL122665A IL 122665 A IL122665 A IL 122665A IL 12266596 A IL12266596 A IL 12266596A IL 12266596 A IL12266596 A IL 12266596A IL 122665 A IL122665 A IL 122665A
Authority
IL
Israel
Prior art keywords
pct
fibrinogen concentrate
viral
fibrinogen
date
Prior art date
Application number
IL12266596A
Other languages
English (en)
Other versions
IL122665A0 (en
Original Assignee
Croix Rouge De Belgique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8218658&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL122665(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Croix Rouge De Belgique filed Critical Croix Rouge De Belgique
Priority claimed from PCT/BE1996/000076 external-priority patent/WO1997003706A1/fr
Publication of IL122665A0 publication Critical patent/IL122665A0/xx
Publication of IL122665A publication Critical patent/IL122665A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0042—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Processing Of Meat And Fish (AREA)
IL12266596A 1994-07-14 1996-07-15 Method and apparatus for inactivating contaminants in blood products IL122665A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94870121 1994-07-14
PCT/BE1995/000069 WO1996002571A1 (fr) 1994-07-14 1995-07-14 Concentre de fibrinogene issu de plasma sanguin, procede et installation pour sa preparation
PCT/BE1996/000076 WO1997003706A1 (fr) 1995-07-14 1996-07-15 Procede et installation d'inactivation de contaminants presents dans des produits sanguins

Publications (2)

Publication Number Publication Date
IL122665A0 IL122665A0 (en) 1998-08-16
IL122665A true IL122665A (en) 2001-08-26

Family

ID=8218658

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12266596A IL122665A (en) 1994-07-14 1996-07-15 Method and apparatus for inactivating contaminants in blood products

Country Status (9)

Country Link
US (1) US5834420A (xx)
EP (1) EP0771324B2 (xx)
JP (1) JP4211894B2 (xx)
AT (1) ATE184884T1 (xx)
CA (1) CA2195127C (xx)
DE (1) DE69512416T3 (xx)
ES (1) ES2139227T5 (xx)
IL (1) IL122665A (xx)
WO (1) WO1996002571A1 (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996002571A1 (fr) * 1994-07-14 1996-02-01 Croix-Rouge De Belgique Concentre de fibrinogene issu de plasma sanguin, procede et installation pour sa preparation
US6190608B1 (en) 1995-07-14 2001-02-20 Croix-Rouge De Beligique Departement Central De Fractionnement Method and apparatus for inactivating contaminants in blood products
WO2000017239A1 (en) * 1998-09-24 2000-03-30 Ppl Therapeutics (Scotland) Limited Purification of fibrinogen from fluids by precipitation and hydrophobic chromatography
AU6104999A (en) 1998-09-24 2000-04-10 Ppl Therapeutics (Scotland) Limited Purification of fibrinogen from milk by use of cation exchange chromatography
FR2785206B1 (fr) * 1998-10-14 2001-01-19 Fond Jean Dausset Ceph Dispositif de centrifugation pour automate de laboratoire
US6946140B1 (en) * 1999-02-09 2005-09-20 The Research Foundation Of State University Of New York Methods and compositions for enhancing fibroblast migration
US6867285B2 (en) 1999-12-20 2005-03-15 Mitsubishi Pharma Corporation Virus-free plasma protein compositions treated with porous membrane and process for producing the same
US6960463B2 (en) * 1999-12-23 2005-11-01 Csl Limited Separation of fibrinogen from plasma proteases
US20030086817A1 (en) * 2001-11-06 2003-05-08 Horton Isaac B. Blood purification system
ES2318145T3 (es) * 2002-02-19 2009-05-01 Resolution Chemicals Limited Esterilizacion de esteroides por medio de disolventes.
WO2004075931A2 (en) 2003-02-27 2004-09-10 Baxter International Inc. Method for the validatable inactivation of pathogens in a biological fluid by irradiation
US20050124038A1 (en) * 2003-07-14 2005-06-09 Pharmacia Corporation Transfection of cartilage and matrices thereof in vitro
ES2403357T3 (es) 2003-12-11 2013-05-17 Isto Technologies Inc. Sistema de cartílago particulado
EP1753860B1 (en) * 2004-02-20 2012-04-11 Isto Technologies Inc. Intervertebral disc repair and methods therefor
DE102004009400A1 (de) * 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
KR101209162B1 (ko) * 2004-06-29 2012-12-06 리라이언스 라이프 사이언시스 프라이빗. 리미티드 바이러스에 안전한 생물학적 유체의 개선 방법
FR2887883B1 (fr) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
US20110033554A1 (en) * 2008-03-28 2011-02-10 Research Foundation For Medical Devices Method of Viral Inactivation of Biological Fluids
ES2586698T3 (es) * 2010-09-20 2016-10-18 Octapharma Ag Proceso para la producción de fibrinógeno
US20140287044A1 (en) * 2011-03-04 2014-09-25 Rare Antibody Antigen Supply, Inc. Fibrin sealant (fibringluraas) consisting of a kit of lyophilized or frozen high concentrate fribinogen
RU2663792C2 (ru) * 2012-03-13 2018-08-09 Октафарма Аг Способ очистки фибриногена, продукт фибриногена и средство для очистки или производства продукта фибриногена
CH706420A1 (fr) * 2012-04-19 2013-10-31 Valerie Soulie Procédé d'inactivation virale d'un fluide biologique, dispositif et récipient pour la mise en œuvre d'un tel procédé.
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
US20140154233A1 (en) 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
IL231230A0 (en) 2014-02-27 2014-08-31 Omrix Biopharmaceuticals Ltd Fibrinogen preparation
US9932388B2 (en) 2014-11-13 2018-04-03 Hemarus Therapeutics Limited Chromatographic process for producing high purity fibrinogen and thrombin
EP4073105A1 (en) * 2019-12-10 2022-10-19 Biotest AG Method for manufacturing a fibrinogen preparation
CN111518197B (zh) * 2020-03-30 2024-01-05 哈尔滨派斯菲科生物制药有限公司 一种纤维蛋白原的生产方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5598196A (en) * 1979-01-16 1980-07-25 Meito Sangyo Kk Fractionation of fibrinogen or its constituents and their use
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
US4481189A (en) † 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
GB8505882D0 (en) * 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii
DE3734923C1 (de) * 1987-10-15 1989-01-26 Biotest Pharma Gmbh Verfahren zur Herstellung einer sterilen Plasmaproteinloesung,die Fibrinogen und den Gerinnungsfaktor XIII enthaelt
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
DE69011136T3 (de) † 1989-01-13 2003-10-23 Mitsubishi Pharma Corp Verfahren zur Herstellung einer Protein enthaltenden Zusammensetzung.
ATE180492T1 (de) * 1991-09-05 1999-06-15 Baxter Int Topischer fibrinogenkomplex
FR2686883B1 (fr) * 1992-02-04 1994-05-13 Aquitaine Develop Transf Sanguin Procede de fabrication de fibrinogene de tres haute purete, fibrinogene de tres haute purete obtenu ainsi qu'une composition pharmaceutique le contenant.
WO1996002571A1 (fr) * 1994-07-14 1996-02-01 Croix-Rouge De Belgique Concentre de fibrinogene issu de plasma sanguin, procede et installation pour sa preparation

Also Published As

Publication number Publication date
CA2195127A1 (en) 1996-02-01
DE69512416D1 (de) 1999-10-28
EP0771324B2 (fr) 2011-02-09
JP4211894B2 (ja) 2009-01-21
ES2139227T3 (es) 2000-02-01
WO1996002571A1 (fr) 1996-02-01
EP0771324A1 (fr) 1997-05-07
DE69512416T3 (de) 2011-12-15
US5834420A (en) 1998-11-10
IL122665A0 (en) 1998-08-16
ES2139227T5 (es) 2011-05-04
CA2195127C (en) 2007-06-19
ATE184884T1 (de) 1999-10-15
EP0771324B1 (fr) 1999-09-22
DE69512416T2 (de) 2000-02-17
JPH10506607A (ja) 1998-06-30

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