DK174745B1 - Ikke-ioniske kontrastmedier ud fra ioniske kontrastmedier - Google Patents

Ikke-ioniske kontrastmedier ud fra ioniske kontrastmedier Download PDF

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Publication number
DK174745B1
DK174745B1 DK198701785A DK178587A DK174745B1 DK 174745 B1 DK174745 B1 DK 174745B1 DK 198701785 A DK198701785 A DK 198701785A DK 178587 A DK178587 A DK 178587A DK 174745 B1 DK174745 B1 DK 174745B1
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DK
Denmark
Prior art keywords
acid
triiodo
reaction
mmol
added
Prior art date
Application number
DK198701785A
Other languages
Danish (da)
English (en)
Other versions
DK178587D0 (da
DK178587A (da
Inventor
Milos Sovak
Ramachandran Ranganathan
Original Assignee
Cook Imaging Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cook Imaging Corp filed Critical Cook Imaging Corp
Publication of DK178587D0 publication Critical patent/DK178587D0/da
Publication of DK178587A publication Critical patent/DK178587A/da
Application granted granted Critical
Publication of DK174745B1 publication Critical patent/DK174745B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK198701785A 1985-08-09 1987-04-08 Ikke-ioniske kontrastmedier ud fra ioniske kontrastmedier DK174745B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US76427485A 1985-08-09 1985-08-09
US76427485 1985-08-09
US8601590 1986-08-01
PCT/US1986/001590 WO1987000757A1 (en) 1985-08-09 1986-08-01 Non-ionic polyol contrast media from ionic contrast media

Publications (3)

Publication Number Publication Date
DK178587D0 DK178587D0 (da) 1987-04-08
DK178587A DK178587A (da) 1987-04-08
DK174745B1 true DK174745B1 (da) 2003-10-13

Family

ID=25070222

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198701785A DK174745B1 (da) 1985-08-09 1987-04-08 Ikke-ioniske kontrastmedier ud fra ioniske kontrastmedier

Country Status (9)

Country Link
EP (1) EP0233249B1 (ja)
JP (1) JPH0813794B2 (ja)
AU (3) AU600672B2 (ja)
CA (1) CA1339666C (ja)
DE (1) DE3689330T2 (ja)
DK (1) DK174745B1 (ja)
HK (1) HK1003564A1 (ja)
NO (1) NO178106C (ja)
WO (1) WO1987000757A1 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4109169A1 (de) * 1991-03-20 1992-09-24 Koehler Chemie Dr Franz Wasserloesliche nicht ionische roentgenkontrastmittel sowie mittel und verfahren zu ihrer herstellung
US5840967A (en) * 1996-08-29 1998-11-24 Nycomed Imaging As Process for the preparation of contrast agents
GB9618055D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
AU2002245169A1 (en) 2000-11-10 2002-07-08 Wm. Marsh Rice University Fullerene (c60)-based x-ray contrast agent for diagnostic imaging
FR2899581B1 (fr) * 2006-04-07 2008-06-27 Guerbet Sa Procede d'atomisation du ioxilan
JP2012514622A (ja) 2009-01-09 2012-06-28 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影製剤組成物
PT108524B (pt) 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA935153A (en) * 1969-06-27 1973-10-09 Nyegaard And Co. A/S 2,4,6-triiodobenzoyl amines used as x-ray contrast agents
BE788054A (fr) * 1971-08-26 1973-02-26 Bracco Ind Chimica Spa Nouvel agent de contraste radiographique et procede pour le preparer
CH608189A5 (ja) * 1974-12-13 1978-12-29 Savac Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
BE877443A (fr) * 1978-07-04 1980-01-03 Nyegaard & Co As Procede de preparation d'unesolution tamponnee d'une substance de contraste pour rayons x
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
IT1193211B (it) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
DE3150916A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
JP2568166B2 (ja) * 1982-10-01 1996-12-25 ニユコメド・イメージング・アクシェセルカペト Ｘ線造影剤

Also Published As

Publication number Publication date
DK178587D0 (da) 1987-04-08
WO1987000757A1 (en) 1987-02-12
AU600672B2 (en) 1990-08-23
AU7415594A (en) 1995-01-05
CA1339666C (en) 1998-02-10
HK1003564A1 (en) 1998-10-30
EP0233249B1 (en) 1993-11-24
NO871474D0 (no) 1987-04-08
AU6197486A (en) 1987-03-05
AU650432B2 (en) 1994-06-23
DE3689330D1 (de) 1994-01-05
DK178587A (da) 1987-04-08
JPS63500522A (ja) 1988-02-25
AU673286B2 (en) 1996-10-31
AU6686690A (en) 1991-06-13
JPH0813794B2 (ja) 1996-02-14
NO178106C (no) 1996-01-24
NO178106B (no) 1995-10-16
EP0233249A4 (en) 1988-10-06
EP0233249A1 (en) 1987-08-26
DE3689330T2 (de) 1994-05-19

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