DK174331B1 - Krystalliserede cephem-syreadditionssalte, dets fremstilling og anvendelse til fremstilling af et lægemiddel samt lægemiddel indeholdende saltet - Google Patents

Krystalliserede cephem-syreadditionssalte, dets fremstilling og anvendelse til fremstilling af et lægemiddel samt lægemiddel indeholdende saltet Download PDF

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Publication number
DK174331B1
DK174331B1 DK198800957A DK95788A DK174331B1 DK 174331 B1 DK174331 B1 DK 174331B1 DK 198800957 A DK198800957 A DK 198800957A DK 95788 A DK95788 A DK 95788A DK 174331 B1 DK174331 B1 DK 174331B1
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DK
Denmark
Prior art keywords
salt
formula
medicament
compound
acid addition
Prior art date
Application number
DK198800957A
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Danish (da)
English (en)
Other versions
DK95788A (da
DK95788D0 (da
Inventor
Rudolf Lattrell
Walter Duerckheimer
Reiner Kirrstetter
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Aventis Pharma Gmbh
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Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of DK95788D0 publication Critical patent/DK95788D0/da
Publication of DK95788A publication Critical patent/DK95788A/da
Application granted granted Critical
Publication of DK174331B1 publication Critical patent/DK174331B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK198800957A 1987-02-25 1988-02-24 Krystalliserede cephem-syreadditionssalte, dets fremstilling og anvendelse til fremstilling af et lægemiddel samt lægemiddel indeholdende saltet DK174331B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873706020 DE3706020A1 (de) 1987-02-25 1987-02-25 Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3706020 1987-02-25

Publications (3)

Publication Number Publication Date
DK95788D0 DK95788D0 (da) 1988-02-24
DK95788A DK95788A (da) 1988-08-26
DK174331B1 true DK174331B1 (da) 2002-12-09

Family

ID=6321729

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198800957A DK174331B1 (da) 1987-02-25 1988-02-24 Krystalliserede cephem-syreadditionssalte, dets fremstilling og anvendelse til fremstilling af et lægemiddel samt lægemiddel indeholdende saltet

Country Status (27)

Country Link
US (1) US4845087A (fr)
EP (1) EP0280157B1 (fr)
JP (1) JP2635078B2 (fr)
KR (1) KR960003617B1 (fr)
AR (1) AR243193A1 (fr)
AT (1) ATE128469T1 (fr)
AU (1) AU621040B2 (fr)
CA (1) CA1297473C (fr)
CS (1) CS274422B2 (fr)
CY (1) CY2023A (fr)
DD (1) DD287505A5 (fr)
DE (2) DE3706020A1 (fr)
DK (1) DK174331B1 (fr)
ES (1) ES2079349T3 (fr)
FI (1) FI91530C (fr)
GR (1) GR3017917T3 (fr)
HU (1) HU200186B (fr)
IE (1) IE69040B1 (fr)
IL (1) IL85521A0 (fr)
MA (1) MA21193A1 (fr)
MX (1) MX10537A (fr)
NO (1) NO880811L (fr)
NZ (1) NZ223594A (fr)
PH (1) PH26857A (fr)
PT (1) PT86826B (fr)
TN (1) TNSN88018A1 (fr)
ZA (1) ZA881282B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4921851A (en) * 1986-06-09 1990-05-01 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
IE61679B1 (en) * 1987-08-10 1994-11-16 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
EP0997466A1 (fr) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Lactam-quinolones antimicrobiennes
DE4440141A1 (de) * 1994-11-10 1996-05-15 Hoechst Ag Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
KR100389284B1 (ko) * 1999-09-30 2003-06-27 (주)정인종합건축사사무소 경첩
US20080318919A1 (en) * 2005-10-29 2008-12-25 Intervet International B.V. Cefquinome Compositions and Methods of Their Use
AR077320A1 (es) * 2009-07-20 2011-08-17 Intervet Int Bv Metodo para la preparacion de particulas de cefquinoma y formulaciones farmaceuticas que las comprenden.
CN102002058B (zh) * 2010-11-05 2012-04-04 山东鲁抗立科药物化学有限公司 硫酸头孢喹肟的合成方法
WO2012095438A1 (fr) 2011-01-12 2012-07-19 Intervet International B.V. Particules et suspensions d'antibiotiques céphalosporine
CN104031069B (zh) * 2014-05-19 2016-05-18 浙江工业大学 一种硫酸头孢喹肟的制备方法
CN111072686B (zh) * 2019-12-30 2021-02-12 济宁市化工研究院(淮海化工研究院) 一种硫酸头孢喹肟的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5657789A (en) * 1979-10-02 1981-05-20 Glaxo Group Ltd Novel cephalosporin antibiotic
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
DE3419015A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von cephalosporinen

Also Published As

Publication number Publication date
IE880503L (en) 1988-08-25
FI880842A (fi) 1988-08-26
IL85521A0 (en) 1988-08-31
US4845087A (en) 1989-07-04
FI91530B (fi) 1994-03-31
ATE128469T1 (de) 1995-10-15
AU621040B2 (en) 1992-03-05
DE3854507D1 (de) 1995-11-02
HUT46695A (en) 1988-11-28
AR243193A1 (es) 1993-07-30
HU200186B (en) 1990-04-28
DD287505A5 (de) 1991-02-28
EP0280157B1 (fr) 1995-09-27
MX10537A (es) 1993-08-01
EP0280157A3 (en) 1990-07-18
CA1297473C (fr) 1992-03-17
AU1210688A (en) 1988-09-01
IE69040B1 (en) 1996-08-07
DK95788A (da) 1988-08-26
FI91530C (fi) 1994-07-11
JP2635078B2 (ja) 1997-07-30
DE3706020A1 (de) 1988-09-08
ES2079349T3 (es) 1996-01-16
GR3017917T3 (en) 1996-01-31
EP0280157A2 (fr) 1988-08-31
MA21193A1 (fr) 1988-10-01
PH26857A (en) 1992-11-16
PT86826B (pt) 1992-05-29
ZA881282B (en) 1988-08-23
DK95788D0 (da) 1988-02-24
NO880811L (no) 1988-08-26
PT86826A (pt) 1988-03-01
KR960003617B1 (en) 1996-03-20
CS113688A2 (en) 1990-08-14
JPH01216995A (ja) 1989-08-30
TNSN88018A1 (fr) 1990-07-10
NO880811D0 (no) 1988-02-24
CS274422B2 (en) 1991-04-11
FI880842A0 (fi) 1988-02-23
NZ223594A (en) 1990-03-27
KR880009973A (ko) 1988-10-06
CY2023A (en) 1998-02-20

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired