DK172543B1 - Fremgangsmåde til fremstilling af 1-N-(omega-amino-alfa-hydroxyalkanoyl)aminoglucosider samt polysilyleret aminoglycosid so - Google Patents

Fremgangsmåde til fremstilling af 1-N-(omega-amino-alfa-hydroxyalkanoyl)aminoglucosider samt polysilyleret aminoglycosid so Download PDF

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Publication number
DK172543B1
DK172543B1 DK197801830A DK183078A DK172543B1 DK 172543 B1 DK172543 B1 DK 172543B1 DK 197801830 A DK197801830 A DK 197801830A DK 183078 A DK183078 A DK 183078A DK 172543 B1 DK172543 B1 DK 172543B1
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DK
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Prior art keywords
groups
amino
acid
formula
aminoglycoside
Prior art date
Application number
DK197801830A
Other languages
Danish (da)
English (en)
Other versions
DK183078A (da
Inventor
Derek Walker
Martin John Cron
John Gerard Keil
Jeng Shyong Lin
Mariano Vecchio Ruggeri
Original Assignee
Squibb Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb Bristol Myers Co filed Critical Squibb Bristol Myers Co
Publication of DK183078A publication Critical patent/DK183078A/da
Application granted granted Critical
Publication of DK172543B1 publication Critical patent/DK172543B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK197801830A 1977-04-28 1978-04-26 Fremgangsmåde til fremstilling af 1-N-(omega-amino-alfa-hydroxyalkanoyl)aminoglucosider samt polysilyleret aminoglycosid so DK172543B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79180677A 1977-04-28 1977-04-28
US79180677 1977-04-28
US88858578A 1978-03-20 1978-03-20
US88858578 1978-03-20

Publications (2)

Publication Number Publication Date
DK183078A DK183078A (da) 1978-10-29
DK172543B1 true DK172543B1 (da) 1998-12-07

Family

ID=27121201

Family Applications (2)

Application Number Title Priority Date Filing Date
DK182978A DK165450C (da) 1977-04-28 1978-04-26 Fremgangsmaade til fremstilling af 1-n-(omega-amino-alfa-hydroxyalkanoyl)kanamycin a eller b
DK197801830A DK172543B1 (da) 1977-04-28 1978-04-26 Fremgangsmåde til fremstilling af 1-N-(omega-amino-alfa-hydroxyalkanoyl)aminoglucosider samt polysilyleret aminoglycosid so

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK182978A DK165450C (da) 1977-04-28 1978-04-26 Fremgangsmaade til fremstilling af 1-n-(omega-amino-alfa-hydroxyalkanoyl)kanamycin a eller b

Country Status (27)

Country Link
JP (1) JPS53149951A (de)
AR (1) AR218910A1 (de)
AT (1) AT357675B (de)
CA (2) CA1100953A (de)
CH (1) CH639104A5 (de)
CS (1) CS207607B2 (de)
CY (1) CY1241A (de)
DE (2) DE2818822A1 (de)
DK (2) DK165450C (de)
EG (1) EG13710A (de)
ES (1) ES469303A1 (de)
FI (1) FI781288A (de)
FR (2) FR2388826A1 (de)
GB (1) GB1598294A (de)
HK (1) HK51484A (de)
IE (2) IE46945B1 (de)
IT (2) IT1156718B (de)
KE (1) KE3398A (de)
LU (1) LU79541A1 (de)
MY (1) MY8500528A (de)
NL (1) NL178790C (de)
NO (2) NO149635C (de)
PL (1) PL117307B1 (de)
PT (1) PT67959B (de)
SE (2) SE447259B (de)
SG (1) SG22884G (de)
YU (2) YU102578A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55306A (en) * 1978-04-28 1980-01-05 Bristol Myers Co Manufacture of 11nn*omegaaaminooalphaahydroxy alkanoyl**aminoglycoside antibiotic
TW200303209A (en) * 2002-02-19 2003-09-01 Amato Pharm Prod Ltd Lactic acid derivative
ES2613936T3 (es) 2007-11-21 2017-05-29 Achaogen, Inc. Análogos de aminoglucósido antibacterianos
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132757A2 (en) * 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin

Also Published As

Publication number Publication date
SE447259B (sv) 1986-11-03
DE2818822C2 (de) 1989-01-26
NO154697B (no) 1986-08-25
IT7849137A0 (it) 1978-04-28
FR2388827A1 (fr) 1978-11-24
AT357675B (de) 1980-07-25
NL178790C (nl) 1986-05-16
IE47271B1 (en) 1984-02-08
YU102478A (en) 1982-10-31
DK183078A (da) 1978-10-29
NL7804503A (nl) 1978-10-31
DK165450C (da) 1993-04-13
MY8500528A (en) 1985-12-31
FR2388826B1 (de) 1982-12-10
JPS53149951A (en) 1978-12-27
SE7804973L (sv) 1978-10-29
GB1598294A (en) 1981-09-16
NL178790B (nl) 1985-12-16
CA1105454A (en) 1981-07-21
IE46945B1 (en) 1983-11-16
NO831197L (no) 1978-10-31
IE780842L (en) 1978-10-28
JPS5721277B2 (de) 1982-05-06
NO154697C (no) 1986-12-03
SG22884G (en) 1985-01-04
CA1100953A (en) 1981-05-12
SE461148B (sv) 1990-01-15
NO149635C (no) 1984-05-23
CH639104A5 (en) 1983-10-31
ATA312778A (de) 1979-12-15
FR2388826A1 (fr) 1978-11-24
CS207607B2 (en) 1981-08-31
LU79541A1 (fr) 1978-11-28
DE2818992A1 (de) 1978-11-23
DE2818822A1 (de) 1978-11-09
KE3398A (en) 1984-06-08
IE780841L (en) 1978-10-28
PT67959A (en) 1978-05-01
ES469303A1 (es) 1979-09-16
DE2818992C2 (de) 1988-03-17
NO781437L (no) 1978-10-31
FR2388827B1 (de) 1982-07-09
PT67959B (en) 1980-03-05
SE8305538D0 (sv) 1983-10-07
IT1105500B (it) 1985-11-04
EG13710A (en) 1982-09-30
NO149635B (no) 1984-02-13
YU41590B (en) 1987-12-31
HK51484A (en) 1984-06-22
DK165450B (da) 1992-11-30
DK182978A (da) 1978-10-29
IT1156718B (it) 1987-02-04
SE8305538L (sv) 1983-10-07
PL206457A1 (de) 1980-03-24
PL117307B1 (en) 1981-07-31
YU102578A (en) 1983-01-21
AR218910A1 (es) 1980-07-15
FI781288A (fi) 1978-10-29
CY1241A (en) 1984-06-29
IT7849136A0 (it) 1978-04-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired