DK172306B1 - Naphthoxazinderivater, fremstilling af disse og naphthoxazinderivaterne til anvendelse som lægemidler, samt farmaceutiske præparater - Google Patents

Naphthoxazinderivater, fremstilling af disse og naphthoxazinderivaterne til anvendelse som lægemidler, samt farmaceutiske præparater Download PDF

Info

Publication number
DK172306B1
DK172306B1 DK259185A DK259185A DK172306B1 DK 172306 B1 DK172306 B1 DK 172306B1 DK 259185 A DK259185 A DK 259185A DK 259185 A DK259185 A DK 259185A DK 172306 B1 DK172306 B1 DK 172306B1
Authority
DK
Denmark
Prior art keywords
carbon atoms
general formula
compounds
acid addition
addition salt
Prior art date
Application number
DK259185A
Other languages
Danish (da)
English (en)
Other versions
DK259185D0 (da
DK259185A (da
Inventor
Joachim Nozulak
Rudolf K A Giger
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK259185D0 publication Critical patent/DK259185D0/da
Publication of DK259185A publication Critical patent/DK259185A/da
Application granted granted Critical
Publication of DK172306B1 publication Critical patent/DK172306B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK259185A 1984-06-12 1985-06-10 Naphthoxazinderivater, fremstilling af disse og naphthoxazinderivaterne til anvendelse som lægemidler, samt farmaceutiske præparater DK172306B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3421729 1984-06-12
DE3421729 1984-06-12
DE3508263 1985-03-08
DE3508263 1985-03-08

Publications (3)

Publication Number Publication Date
DK259185D0 DK259185D0 (da) 1985-06-10
DK259185A DK259185A (da) 1985-12-13
DK172306B1 true DK172306B1 (da) 1998-03-09

Family

ID=25822036

Family Applications (1)

Application Number Title Priority Date Filing Date
DK259185A DK172306B1 (da) 1984-06-12 1985-06-10 Naphthoxazinderivater, fremstilling af disse og naphthoxazinderivaterne til anvendelse som lægemidler, samt farmaceutiske præparater

Country Status (28)

Country Link
US (1) US4656167A (nl)
JP (1) JPS611676A (nl)
AT (1) AT394717B (nl)
AU (1) AU582751B2 (nl)
BE (1) BE902600A (nl)
CA (1) CA1285561C (nl)
CH (1) CH666031A5 (nl)
CY (1) CY1581A (nl)
DE (1) DE3520104C2 (nl)
DK (1) DK172306B1 (nl)
ES (1) ES8704469A1 (nl)
FI (1) FI86301C (nl)
FR (1) FR2565586B1 (nl)
GB (1) GB2160200B (nl)
GR (1) GR851418B (nl)
HK (1) HK11891A (nl)
HU (1) HU193979B (nl)
IE (1) IE58398B1 (nl)
IL (1) IL75468A (nl)
IT (1) IT1200079B (nl)
LU (1) LU85941A1 (nl)
MY (1) MY102059A (nl)
NL (1) NL194166C (nl)
NZ (1) NZ212358A (nl)
PH (1) PH23666A (nl)
PT (1) PT80634B (nl)
SE (1) SE465428B (nl)
SG (1) SG9691G (nl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8616669D0 (en) * 1986-07-09 1986-08-13 Merk Sharpe & Dohme Ltd Pharmaceutical compositions
US5071875A (en) * 1989-09-25 1991-12-10 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
HU214591B (hu) * 1989-12-14 1998-04-28 Novartis Ag. Eljárás egy naftoxazinszármazék malonátsójának és az ilyen hatóanyagot tartalmazó gyógyszerkészítmények előállítására
DE4329776A1 (de) * 1993-09-03 1995-03-09 Sandoz Ag Naphthoxazine, ihre Herstellung und Verwendung
TW357143B (en) * 1995-07-07 1999-05-01 Novartis Ag Benzo[g]quinoline derivatives
JP2011525893A (ja) * 2008-06-27 2011-09-29 ハー・ルンドベック・アクチエゼルスカベット 新規のフェノールアミン類およびカテコールアミン類ならびにそのプロドラッグ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2194421B1 (nl) * 1972-08-03 1975-10-17 Cerpha
AU521527B2 (en) * 1979-09-12 1982-04-08 Dow Chemical Company, The Dehydrohalogenation of (polyhaloalkyl) benzenes
US4368201A (en) * 1981-07-20 1983-01-11 Usv Pharmaceutical Corporation Tetrahydronaphthoxazoles
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
CA1204745A (en) * 1981-11-20 1986-05-20 Merck Co. Hexahydronaphth (1,2-b) -1,4 -oxazines
DE4003262A1 (de) * 1990-02-03 1991-08-08 Sandoz Ag Neues naphthoxazin, seine herstellung und verwendung

Also Published As

Publication number Publication date
GB2160200A (en) 1985-12-18
IL75468A (en) 1989-05-15
HUT39438A (en) 1986-09-29
LU85941A1 (fr) 1986-01-24
FI852325L (fi) 1985-12-13
GB2160200B (en) 1988-03-16
SE8502865D0 (sv) 1985-06-10
CY1581A (en) 1992-04-03
NZ212358A (en) 1989-01-27
DE3520104A1 (de) 1985-12-12
FI852325A0 (fi) 1985-06-11
FI86301C (fi) 1992-08-10
FR2565586B1 (fr) 1989-09-15
ATA172385A (de) 1991-11-15
JPS611676A (ja) 1986-01-07
DE3520104C2 (de) 1997-01-23
IL75468A0 (en) 1985-10-31
HU193979B (en) 1987-12-28
IE58398B1 (en) 1993-09-08
FR2565586A1 (fr) 1985-12-13
IT8548195A0 (it) 1985-06-11
NL8501526A (nl) 1986-01-02
AT394717B (de) 1992-06-10
AU582751B2 (en) 1989-04-13
PT80634B (pt) 1987-10-20
DK259185D0 (da) 1985-06-10
IE851437L (en) 1985-12-12
FI86301B (fi) 1992-04-30
PH23666A (en) 1989-09-27
CA1285561C (en) 1991-07-02
ES8704469A1 (es) 1987-04-01
SG9691G (en) 1991-04-05
NL194166C (nl) 2001-08-03
PT80634A (en) 1985-07-01
NL194166B (nl) 2001-04-02
DK259185A (da) 1985-12-13
GR851418B (nl) 1985-11-25
SE8502865L (sv) 1985-12-13
SE465428B (sv) 1991-09-09
BE902600A (fr) 1985-12-06
CH666031A5 (de) 1988-06-30
AU4345885A (en) 1985-12-19
ES544074A0 (es) 1987-04-01
US4656167A (en) 1987-04-07
JPH0576472B2 (nl) 1993-10-22
IT1200079B (it) 1989-01-05
HK11891A (en) 1991-02-22
MY102059A (en) 1992-03-31
GB8514636D0 (en) 1985-07-10

Similar Documents

Publication Publication Date Title
EP0074304B1 (fr) Ethers tricycliques, leur préparation et les compositions pharmaceutiques les contenant
FI113862B (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten 1-piperatsino-1,2-dihydroindeenijohdannaisten valmistamiseksi
BG62048B1 (bg) Хиполипидемични 1,4-бензотиазепин-1,1-диоксиди
EP0243018B1 (en) Thiolactam-n-acetic acid derivatives, their production and use
DK160820B (da) Analogifremgangsmaade til fremstilling af 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinolinderivater
EP0080115B1 (en) Hexahydronaphth(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical formulation containing them
US4420480A (en) Hexahydronaphth[1,2-b]-1,4-oxazines
DK172306B1 (da) Naphthoxazinderivater, fremstilling af disse og naphthoxazinderivaterne til anvendelse som lægemidler, samt farmaceutiske præparater
US4243805A (en) 3 Fluoro-10-piperazino-8-substituted 10,11-dihydrodibenzo-(bf) thiepins and method for the preparation thereof
US5084454A (en) 2-(piperidinylmethyl)-4-phenyl-2,3-dihydro-4h-1,4-benzoxazines useful as antipsychotics
NO811229L (no) Fremgangsmaate ved fremstilling av nye tricykliske etere
EP0003016B1 (en) Pyrazino-benzoxazepine and -benzthiazepine derivatives, processes for their production and pharmaceutical compositions containing them
DK166584B1 (da) Substituerede 4-benzyl-1h-imidazoler, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende dem
US4237135A (en) 2-(4-Ethyl-1-piperazinyl)-4-phenylquinoline, process for preparation thereof, and composition thereof
IE55377B1 (en) 1,5-diphenylpyrazolin-3-one compounds,method for preparing them,and pharmaceutical compositions containing these compounds
US4672064A (en) 1,5-benzoxathiepin derivatives, their production and use
EP2935254A1 (en) Compounds of 2,3-dihydro-4h-1,3-benzoxazine-4-one, method for preparing them and pharmaceutical form comprising them
EP0205264B1 (en) Condensed seven-membered heterocyclic compounds, their production and use
RU2295521C2 (ru) Фотохромные оксазиновые соединения и способы их производства
JPS6130588A (ja) ベンゾ〔ｃ〕〔１，８〕ナフチリジン、その製造方法及びその使用、並びにこれらの化合物を含有する調製剤
CS196399B2 (en) Process for preparing 2-substituted 1-/omega-amino-alkoxy/-benzenes
US4147871A (en) Cyclohexanetetrol derivatives
HUT61997A (en) Process for producing benzopyran derivatives, as well as antihypertensive and vasodilator pharmaceutical compositions comprising such compounds
US4302453A (en) Antiarrhythmic tetrahydronaphthalene derivatives
PL150777B1 (pl) Sposób wytwarzania naftooksazyn

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK