DK172094B1 - 1,4-Dihydropyridin-forbindelser, farmaceutiske præparater indeholdende disse og deres anvendelse til deres fremstilling af lægemidler samt beskyttede derivater deraf til anvendelse som udgangsmateriale ved deres fremstilling - Google Patents
1,4-Dihydropyridin-forbindelser, farmaceutiske præparater indeholdende disse og deres anvendelse til deres fremstilling af lægemidler samt beskyttede derivater deraf til anvendelse som udgangsmateriale ved deres fremstilling Download PDFInfo
- Publication number
- DK172094B1 DK172094B1 DK264388A DK234388A DK172094B1 DK 172094 B1 DK172094 B1 DK 172094B1 DK 264388 A DK264388 A DK 264388A DK 234388 A DK234388 A DK 234388A DK 172094 B1 DK172094 B1 DK 172094B1
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- cycloocta
- amylose
- starch
- dioxa
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Dental Preparations (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8710493 | 1987-05-02 | ||
GB878710493A GB8710493D0 (en) | 1987-05-02 | 1987-05-02 | Dihydropyridines |
Publications (3)
Publication Number | Publication Date |
---|---|
DK234388D0 DK234388D0 (da) | 1988-04-28 |
DK234388A DK234388A (da) | 1989-01-19 |
DK172094B1 true DK172094B1 (da) | 1997-10-20 |
Family
ID=10616773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK264388A DK172094B1 (da) | 1987-05-02 | 1988-04-28 | 1,4-Dihydropyridin-forbindelser, farmaceutiske præparater indeholdende disse og deres anvendelse til deres fremstilling af lægemidler samt beskyttede derivater deraf til anvendelse som udgangsmateriale ved deres fremstilling |
Country Status (13)
Country | Link |
---|---|
US (1) | US4806557A (fi) |
EP (1) | EP0290211B1 (fi) |
JP (1) | JPS63297365A (fi) |
AT (1) | ATE66915T1 (fi) |
CA (1) | CA1326672C (fi) |
DE (1) | DE3864573D1 (fi) |
DK (1) | DK172094B1 (fi) |
ES (1) | ES2031595T3 (fi) |
FI (1) | FI90415C (fi) |
GB (1) | GB8710493D0 (fi) |
GR (1) | GR3002767T3 (fi) |
IE (1) | IE60055B1 (fi) |
PT (1) | PT87361B (fi) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5270323A (en) * | 1990-05-31 | 1993-12-14 | Pfizer Inc. | Method of treating impotence |
US6057344A (en) * | 1991-11-26 | 2000-05-02 | Sepracor, Inc. | Methods for treating hypertension, and angina using optically pure (-) amlodipine |
DE60005017T2 (de) * | 1999-06-25 | 2004-06-09 | Vertex Pharmaceuticals Inc., Cambridge | Prodrugs von impdh-inhibierenden carbamaten |
US6521647B2 (en) | 2000-04-04 | 2003-02-18 | Pfizer Inc. | Treatment of renal disorders |
GB0008332D0 (en) * | 2000-04-04 | 2000-05-24 | Pfizer Ltd | Treament |
EP1309556B1 (en) | 2000-12-29 | 2004-11-24 | Pfizer Limited | Amlodipine fumarate |
AT5874U1 (de) | 2000-12-29 | 2003-01-27 | Bioorg Bv | Pharmazeutische zubereitungen enthaltend amlodipinmaleat |
BR0116553A (pt) | 2000-12-29 | 2004-02-03 | Pfizer Ltd | Composto, composição farmacêutica para tratamento de angina ou hipertensão, processo, processo para tratamento ou prevenção de angina ou hipertensão, composição de ingredientes farmaceuticamente ativos, composição farmacêutica para tratamento ou prevenção de angina ou hipertensão e processo para tratar ou prevenir angina ou hipertensão |
US6653481B2 (en) | 2000-12-29 | 2003-11-25 | Synthon Bv | Process for making amlodipine |
CN1272319C (zh) | 2000-12-29 | 2006-08-30 | 辉瑞有限公司 | 制备氨氯地平马来酸盐的工艺、所制得的氨氯地平马来酸盐、其药物组合物和用途 |
ATE315026T1 (de) | 2000-12-29 | 2006-02-15 | Pfizer Ltd | Amlodipin-hemimaleat |
WO2002054062A2 (en) | 2000-12-29 | 2002-07-11 | Pfizer Limited | Reference standards and processes for determining the purity or stability of amlodipine maleate |
EP1309554A1 (en) | 2000-12-29 | 2003-05-14 | Synthon Licensing, Ltd. | Amide derivative of amlodipine |
MXPA03005882A (es) | 2000-12-29 | 2005-04-19 | Pfizer Ltd | Derivado amida de amlodipina. |
US7335380B2 (en) | 2000-12-29 | 2008-02-26 | Synthon Ip Inc. | Amlodipine free base |
US6699892B2 (en) | 2002-06-04 | 2004-03-02 | Yung Shin Pharmaceutical Industrial Co., Ltd. | Pharmaceutically acceptable salt of amlodipine and method of preparing the same |
KR20040011751A (ko) * | 2002-07-30 | 2004-02-11 | 씨제이 주식회사 | 암로디핀의 유기산염 |
KR100538641B1 (ko) * | 2002-07-30 | 2005-12-22 | 씨제이 주식회사 | 암로디핀의 유기산염 |
KR100496436B1 (ko) * | 2002-07-30 | 2005-06-20 | 씨제이 주식회사 | 암로디핀의 유기산염 |
KR100462304B1 (ko) * | 2002-07-30 | 2004-12-17 | 씨제이 주식회사 | 암로디핀의 유기산염 |
KR100467669B1 (ko) * | 2002-08-21 | 2005-01-24 | 씨제이 주식회사 | 암로디핀의 유기산염 |
TWI583383B (zh) | 2010-05-03 | 2017-05-21 | 東生華製藥股份有限公司 | 治療高血壓之醫藥組成物及方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1552911A (en) * | 1975-07-02 | 1979-09-19 | Fujisawa Pharmaceutical Co | 1,4 dihydropyridine derivatives and the preparation thereof |
US4447613A (en) * | 1979-08-24 | 1984-05-08 | Zoecon Corporation | Pyridyl esters and thiolesters of aminoalkanoic acids |
CS228917B2 (en) * | 1981-03-14 | 1984-05-14 | Pfizer | Method of preparing substituted derivatives of 1,4-dihydropyridine |
DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
GB8306666D0 (en) * | 1983-03-10 | 1983-04-13 | Pfizer Ltd | Therapeutic agents |
US4568677A (en) * | 1983-07-23 | 1986-02-04 | Pfizer Inc. | 2-(4-Pyrimidone alkoxyalkyl) dihydropyridine anti-ischaemic and antihypertensive agents |
-
1987
- 1987-05-02 GB GB878710493A patent/GB8710493D0/en active Pending
-
1988
- 1988-04-28 DK DK264388A patent/DK172094B1/da not_active IP Right Cessation
- 1988-04-28 US US07/187,116 patent/US4806557A/en not_active Expired - Lifetime
- 1988-04-28 FI FI882001A patent/FI90415C/fi not_active IP Right Cessation
- 1988-04-29 IE IE128388A patent/IE60055B1/en not_active IP Right Cessation
- 1988-04-29 PT PT87361A patent/PT87361B/pt not_active IP Right Cessation
- 1988-04-29 ES ES198888303940T patent/ES2031595T3/es not_active Expired - Lifetime
- 1988-04-29 AT AT88303940T patent/ATE66915T1/de not_active IP Right Cessation
- 1988-04-29 CA CA000565483A patent/CA1326672C/en not_active Expired - Fee Related
- 1988-04-29 DE DE8888303940T patent/DE3864573D1/de not_active Expired - Lifetime
- 1988-04-29 EP EP88303940A patent/EP0290211B1/en not_active Expired - Lifetime
- 1988-04-30 JP JP63108909A patent/JPS63297365A/ja active Granted
-
1991
- 1991-09-20 GR GR91401379T patent/GR3002767T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0290211A1 (en) | 1988-11-09 |
FI882001A (fi) | 1988-11-03 |
DK234388A (da) | 1989-01-19 |
DE3864573D1 (en) | 1991-10-10 |
US4806557A (en) | 1989-02-21 |
PT87361B (pt) | 1992-08-31 |
GB8710493D0 (en) | 1987-06-03 |
FI90415B (fi) | 1993-10-29 |
IE881283L (en) | 1988-11-02 |
FI882001A0 (fi) | 1988-04-28 |
ATE66915T1 (de) | 1991-09-15 |
IE60055B1 (en) | 1994-05-18 |
GR3002767T3 (en) | 1993-01-25 |
EP0290211B1 (en) | 1991-09-04 |
FI90415C (fi) | 1994-02-10 |
JPH0581588B2 (fi) | 1993-11-15 |
CA1326672C (en) | 1994-02-01 |
ES2031595T3 (es) | 1992-12-16 |
PT87361A (pt) | 1989-05-31 |
DK234388D0 (da) | 1988-04-28 |
JPS63297365A (ja) | 1988-12-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |