DK170974B1 - 2-Aza-4-(alkoxycarbonyl)spiro[4,5]decan-3-oner samt fremgangsmåde og mellemprodukt til fremstilling deraf - Google Patents

2-Aza-4-(alkoxycarbonyl)spiro[4,5]decan-3-oner samt fremgangsmåde og mellemprodukt til fremstilling deraf Download PDF

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Publication number
DK170974B1
DK170974B1 DK430689A DK430689A DK170974B1 DK 170974 B1 DK170974 B1 DK 170974B1 DK 430689 A DK430689 A DK 430689A DK 430689 A DK430689 A DK 430689A DK 170974 B1 DK170974 B1 DK 170974B1
Authority
DK
Denmark
Prior art keywords
formula
aza
coor
decan
spiro
Prior art date
Application number
DK430689A
Other languages
Danish (da)
English (en)
Other versions
DK430689D0 (da
DK430689A (da
Inventor
Hans Peter Mettler
Gareth Griffiths
Lester Mills
Felix Previdoli
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of DK430689D0 publication Critical patent/DK430689D0/da
Publication of DK430689A publication Critical patent/DK430689A/da
Application granted granted Critical
Publication of DK170974B1 publication Critical patent/DK170974B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK430689A 1988-09-01 1989-08-31 2-Aza-4-(alkoxycarbonyl)spiro[4,5]decan-3-oner samt fremgangsmåde og mellemprodukt til fremstilling deraf DK170974B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH327288 1988-09-01
CH327288 1988-09-01
CH138289 1989-04-12
CH138389 1989-04-12
CH138289 1989-04-12
CH138389 1989-04-12

Publications (3)

Publication Number Publication Date
DK430689D0 DK430689D0 (da) 1989-08-31
DK430689A DK430689A (da) 1990-03-02
DK170974B1 true DK170974B1 (da) 1996-04-09

Family

ID=27172939

Family Applications (2)

Application Number Title Priority Date Filing Date
DK430689A DK170974B1 (da) 1988-09-01 1989-08-31 2-Aza-4-(alkoxycarbonyl)spiro[4,5]decan-3-oner samt fremgangsmåde og mellemprodukt til fremstilling deraf
DK003095A DK170929B1 (da) 1988-09-01 1995-01-11 Fremgangsmåde til fremstilling af 2-aza-4-(alkoxycarbonyl)spiro[4,5]decan-3-oner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK003095A DK170929B1 (da) 1988-09-01 1995-01-11 Fremgangsmåde til fremstilling af 2-aza-4-(alkoxycarbonyl)spiro[4,5]decan-3-oner

Country Status (12)

Country Link
US (2) US4956473A (pt)
EP (1) EP0358092B1 (pt)
JP (1) JPH02115165A (pt)
CA (1) CA1337769C (pt)
DE (1) DE58900561D1 (pt)
DK (2) DK170974B1 (pt)
ES (1) ES2027057T3 (pt)
FI (1) FI90862C (pt)
IL (1) IL91411A (pt)
NO (1) NO173497C (pt)
PT (1) PT91612B (pt)
YU (1) YU162789A (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3928184A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte
PH27359A (en) * 1989-08-25 1993-06-21 Warner Lambert Co Process for cyclic amino acid anticonvulsant compounds
US5149870A (en) * 1989-11-16 1992-09-22 Lonza Ltd. Process for the production of 1-(aminomethyl)cyclohexane acetic acid
US5136091A (en) * 1989-11-16 1992-08-04 Lonza Ltd. Process for the production of 1-(aminomethyl) cyclohexane acetic acid
FI905584A (fi) * 1989-11-16 1991-05-17 Lonza Ag Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra.
BR9708200A (pt) * 1996-03-14 1999-07-27 Warner Lambert Co Aminoácidos cíclicos substituídos como agentes farmacéuticos
US6372792B1 (en) 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
USD386310S (en) * 1996-10-08 1997-11-18 Nepsco, Inc. Shoulder carrying strap
WO1999018063A2 (en) 1997-10-07 1999-04-15 Warner-Lambert Company Process for preparing a cyclic amino acid anticonvulsant compound
US20050148792A1 (en) * 2004-01-02 2005-07-07 Damodaragounder Gopal Process for the preparation of gabapentin
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
CN101484413B (zh) * 2006-06-30 2014-05-14 Zach系统股份公司 制备加巴喷丁的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1350582A (en) * 1970-07-24 1974-04-18 Ucb Sa Cerivatives of 2-pyrrolidinone
GB1415338A (en) * 1971-12-16 1975-11-26 American Home Prod Amino acids and derivatives thereof
GB1385846A (en) * 1973-05-18 1975-03-05 Le G Venny Ped I Im A I Gertse Chlorohydrate of beta-phenyl-ypsilon-amino butyric acid and process for producing same
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2541855A1 (de) * 1975-09-18 1977-03-31 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone ii
DE2611690A1 (de) * 1976-03-19 1977-09-22 Goedecke Ag Cyclische sulfonyloxyimide
DE3631414A1 (de) * 1986-09-16 1988-03-24 Basf Ag Verfahren zur herstellung von (alpha)-pyrrolidonen, deren verwendung und neue (alpha)-pyrrolidone
JP2807277B2 (ja) * 1988-08-31 1998-10-08 第一製薬株式会社 スピロ化合物

Also Published As

Publication number Publication date
EP0358092A1 (de) 1990-03-14
EP0358092B1 (de) 1991-12-11
DK430689D0 (da) 1989-08-31
NO893491D0 (no) 1989-08-31
FI90862C (fi) 1994-04-11
IL91411A (en) 1994-07-31
IL91411A0 (en) 1990-04-29
ES2027057T3 (es) 1992-05-16
NO173497C (no) 1993-12-22
FI894121A0 (fi) 1989-09-01
NO173497B (no) 1993-09-13
FI90862B (fi) 1993-12-31
CA1337769C (en) 1995-12-19
JPH02115165A (ja) 1990-04-27
DK170929B1 (da) 1996-03-18
YU162789A (en) 1990-12-31
NO893491L (no) 1990-03-02
DE58900561D1 (de) 1992-01-23
US4958044A (en) 1990-09-18
PT91612A (pt) 1990-03-30
FI894121A (fi) 1990-03-02
DK3095A (da) 1995-01-11
PT91612B (pt) 1995-05-31
US4956473A (en) 1990-09-11
DK430689A (da) 1990-03-02

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment