ES2027057T3 - Procedimiento para preparar 2-aza-4-(alcoxicarbonil)espiro(4,5)decan-3-onas. - Google Patents

Procedimiento para preparar 2-aza-4-(alcoxicarbonil)espiro(4,5)decan-3-onas.

Info

Publication number
ES2027057T3
ES2027057T3 ES198989115938T ES89115938T ES2027057T3 ES 2027057 T3 ES2027057 T3 ES 2027057T3 ES 198989115938 T ES198989115938 T ES 198989115938T ES 89115938 T ES89115938 T ES 89115938T ES 2027057 T3 ES2027057 T3 ES 2027057T3
Authority
ES
Spain
Prior art keywords
aza
procedure
alcoxicarbonil
onas
decan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198989115938T
Other languages
English (en)
Inventor
Hans Peter Dr. Mettler
Gareth Dr. Griffiths
Lester Dr. Mills
Felix Dr. Previdoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Application granted granted Critical
Publication of ES2027057T3 publication Critical patent/ES2027057T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/45Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54Spiro-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Abstract

EL INVENTO SE REFIERE A UNA 2 - AZA - 4 - (ALCOXICARBONILO) ESPIRO (4,5) DECANO - 3 - ONA. TAMBIEN SE DESCRIBE EN EL INVENTO UN PROCEDIMIENTO PARA LA PRODUCCION DEL 2 - AZA - 4 - (ALCOXICARBONILO) ESPIRO - [4,5] DECANO - 3 ONA A PARTIR DE ESTERES DE LOS ACIDOS CIDOHEXILIDENOMALONICO O ALQUILATOS DE LOS CICLOHEXILIDENOCIANO. ASI MISMO TRATA EL INVENTO DE LA APLICACION DE ESTOS PRODUCTOS PARA PRODUCIR ACIDOS 1 - (AMINOMETILO) CICLOHOXANO ACETICO.
ES198989115938T 1988-09-01 1989-08-29 Procedimiento para preparar 2-aza-4-(alcoxicarbonil)espiro(4,5)decan-3-onas. Expired - Lifetime ES2027057T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH327288 1988-09-01
CH138289 1989-04-12
CH138389 1989-04-12

Publications (1)

Publication Number Publication Date
ES2027057T3 true ES2027057T3 (es) 1992-05-16

Family

ID=27172939

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198989115938T Expired - Lifetime ES2027057T3 (es) 1988-09-01 1989-08-29 Procedimiento para preparar 2-aza-4-(alcoxicarbonil)espiro(4,5)decan-3-onas.

Country Status (12)

Country Link
US (2) US4956473A (es)
EP (1) EP0358092B1 (es)
JP (1) JPH02115165A (es)
CA (1) CA1337769C (es)
DE (1) DE58900561D1 (es)
DK (2) DK170974B1 (es)
ES (1) ES2027057T3 (es)
FI (1) FI90862C (es)
IL (1) IL91411A (es)
NO (1) NO173497C (es)
PT (1) PT91612B (es)
YU (1) YU162789A (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY106864A (en) * 1989-08-25 1995-08-30 Warner Lambert Co Improved process for cyclic amino acid anticonvulsant compounds.
DE3928184A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte
FI905584A (fi) * 1989-11-16 1991-05-17 Lonza Ag Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra.
US5149870A (en) * 1989-11-16 1992-09-22 Lonza Ltd. Process for the production of 1-(aminomethyl)cyclohexane acetic acid
US5136091A (en) * 1989-11-16 1992-08-04 Lonza Ltd. Process for the production of 1-(aminomethyl) cyclohexane acetic acid
NZ331143A (en) * 1996-03-14 2001-06-29 Warner Lambert Co Substituted cyclic amino acids as pharmaceutical agents
US6372792B1 (en) 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
USD386310S (en) * 1996-10-08 1997-11-18 Nepsco, Inc. Shoulder carrying strap
AU9318398A (en) 1997-10-07 1999-04-27 Warner-Lambert Company Process for preparing a cyclic amino acid anticonvulsant compound
US20050148792A1 (en) * 2004-01-02 2005-07-07 Damodaragounder Gopal Process for the preparation of gabapentin
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
EP2038249B1 (en) * 2006-06-30 2013-09-11 ZaCh System S.p.A. Process for preparing gabapentin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1350582A (en) * 1970-07-24 1974-04-18 Ucb Sa Cerivatives of 2-pyrrolidinone
GB1415338A (en) * 1971-12-16 1975-11-26 American Home Prod Amino acids and derivatives thereof
GB1385846A (en) * 1973-05-18 1975-03-05 Le G Venny Ped I Im A I Gertse Chlorohydrate of beta-phenyl-ypsilon-amino butyric acid and process for producing same
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2541855A1 (de) * 1975-09-18 1977-03-31 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone ii
DE2611690A1 (de) * 1976-03-19 1977-09-22 Goedecke Ag Cyclische sulfonyloxyimide
DE3631414A1 (de) * 1986-09-16 1988-03-24 Basf Ag Verfahren zur herstellung von (alpha)-pyrrolidonen, deren verwendung und neue (alpha)-pyrrolidone
JP2807277B2 (ja) * 1988-08-31 1998-10-08 第一製薬株式会社 スピロ化合物

Also Published As

Publication number Publication date
DK3095A (da) 1995-01-11
EP0358092B1 (de) 1991-12-11
JPH02115165A (ja) 1990-04-27
DK430689D0 (da) 1989-08-31
NO893491D0 (no) 1989-08-31
IL91411A0 (en) 1990-04-29
US4958044A (en) 1990-09-18
FI894121A (fi) 1990-03-02
DE58900561D1 (de) 1992-01-23
NO893491L (no) 1990-03-02
DK170929B1 (da) 1996-03-18
FI90862B (fi) 1993-12-31
PT91612A (pt) 1990-03-30
DK430689A (da) 1990-03-02
DK170974B1 (da) 1996-04-09
IL91411A (en) 1994-07-31
NO173497C (no) 1993-12-22
FI894121A0 (fi) 1989-09-01
NO173497B (no) 1993-09-13
EP0358092A1 (de) 1990-03-14
US4956473A (en) 1990-09-11
YU162789A (en) 1990-12-31
FI90862C (fi) 1994-04-11
CA1337769C (en) 1995-12-19
PT91612B (pt) 1995-05-31

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