NO173497C - 2-aza-4-(alkoksykarbonyl)spiro(4,5)-dekan-3-on, en fremgangsmaate ved fremstilling derav, og (1-cyanocyklo-heksyl)-malonsyredialkylester som mellomprodukt i fremgangsmaaten - Google Patents

2-aza-4-(alkoksykarbonyl)spiro(4,5)-dekan-3-on, en fremgangsmaate ved fremstilling derav, og (1-cyanocyklo-heksyl)-malonsyredialkylester som mellomprodukt i fremgangsmaaten

Info

Publication number
NO173497C
NO173497C NO893491A NO893491A NO173497C NO 173497 C NO173497 C NO 173497C NO 893491 A NO893491 A NO 893491A NO 893491 A NO893491 A NO 893491A NO 173497 C NO173497 C NO 173497C
Authority
NO
Norway
Prior art keywords
cyanocyclohexyl
decan
aza
spiro
alkoxycarbonyl
Prior art date
Application number
NO893491A
Other languages
English (en)
Other versions
NO893491D0 (no
NO173497B (no
NO893491L (no
Inventor
Hans Peter Mettler
Gareth Griffiths
Lester Mills
Felix Previdoli
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of NO893491D0 publication Critical patent/NO893491D0/no
Publication of NO893491L publication Critical patent/NO893491L/no
Publication of NO173497B publication Critical patent/NO173497B/no
Publication of NO173497C publication Critical patent/NO173497C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/45Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54Spiro-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO893491A 1988-09-01 1989-08-31 2-aza-4-(alkoksykarbonyl)spiro(4,5)-dekan-3-on, en fremgangsmaate ved fremstilling derav, og (1-cyanocyklo-heksyl)-malonsyredialkylester som mellomprodukt i fremgangsmaaten NO173497C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH327288 1988-09-01
CH138289 1989-04-12
CH138389 1989-04-12

Publications (4)

Publication Number Publication Date
NO893491D0 NO893491D0 (no) 1989-08-31
NO893491L NO893491L (no) 1990-03-02
NO173497B NO173497B (no) 1993-09-13
NO173497C true NO173497C (no) 1993-12-22

Family

ID=27172939

Family Applications (1)

Application Number Title Priority Date Filing Date
NO893491A NO173497C (no) 1988-09-01 1989-08-31 2-aza-4-(alkoksykarbonyl)spiro(4,5)-dekan-3-on, en fremgangsmaate ved fremstilling derav, og (1-cyanocyklo-heksyl)-malonsyredialkylester som mellomprodukt i fremgangsmaaten

Country Status (12)

Country Link
US (2) US4956473A (no)
EP (1) EP0358092B1 (no)
JP (1) JPH02115165A (no)
CA (1) CA1337769C (no)
DE (1) DE58900561D1 (no)
DK (2) DK170974B1 (no)
ES (1) ES2027057T3 (no)
FI (1) FI90862C (no)
IL (1) IL91411A (no)
NO (1) NO173497C (no)
PT (1) PT91612B (no)
YU (1) YU162789A (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3928184A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte
PH27359A (en) * 1989-08-25 1993-06-21 Warner Lambert Co Process for cyclic amino acid anticonvulsant compounds
US5149870A (en) * 1989-11-16 1992-09-22 Lonza Ltd. Process for the production of 1-(aminomethyl)cyclohexane acetic acid
US5136091A (en) * 1989-11-16 1992-08-04 Lonza Ltd. Process for the production of 1-(aminomethyl) cyclohexane acetic acid
FI905584A (fi) * 1989-11-16 1991-05-17 Lonza Ag Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra.
BR9708200A (pt) * 1996-03-14 1999-07-27 Warner Lambert Co Aminoácidos cíclicos substituídos como agentes farmacéuticos
US6372792B1 (en) 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
USD386310S (en) * 1996-10-08 1997-11-18 Nepsco, Inc. Shoulder carrying strap
WO1999018063A2 (en) 1997-10-07 1999-04-15 Warner-Lambert Company Process for preparing a cyclic amino acid anticonvulsant compound
US20050148792A1 (en) * 2004-01-02 2005-07-07 Damodaragounder Gopal Process for the preparation of gabapentin
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
CN101484413B (zh) * 2006-06-30 2014-05-14 Zach系统股份公司 制备加巴喷丁的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1350582A (en) * 1970-07-24 1974-04-18 Ucb Sa Cerivatives of 2-pyrrolidinone
GB1415338A (en) * 1971-12-16 1975-11-26 American Home Prod Amino acids and derivatives thereof
GB1385846A (en) * 1973-05-18 1975-03-05 Le G Venny Ped I Im A I Gertse Chlorohydrate of beta-phenyl-ypsilon-amino butyric acid and process for producing same
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2541855A1 (de) * 1975-09-18 1977-03-31 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone ii
DE2611690A1 (de) * 1976-03-19 1977-09-22 Goedecke Ag Cyclische sulfonyloxyimide
DE3631414A1 (de) * 1986-09-16 1988-03-24 Basf Ag Verfahren zur herstellung von (alpha)-pyrrolidonen, deren verwendung und neue (alpha)-pyrrolidone
JP2807277B2 (ja) * 1988-08-31 1998-10-08 第一製薬株式会社 スピロ化合物

Also Published As

Publication number Publication date
EP0358092A1 (de) 1990-03-14
EP0358092B1 (de) 1991-12-11
DK430689D0 (da) 1989-08-31
NO893491D0 (no) 1989-08-31
FI90862C (fi) 1994-04-11
IL91411A (en) 1994-07-31
IL91411A0 (en) 1990-04-29
ES2027057T3 (es) 1992-05-16
FI894121A0 (fi) 1989-09-01
NO173497B (no) 1993-09-13
FI90862B (fi) 1993-12-31
CA1337769C (en) 1995-12-19
JPH02115165A (ja) 1990-04-27
DK170929B1 (da) 1996-03-18
YU162789A (en) 1990-12-31
NO893491L (no) 1990-03-02
DE58900561D1 (de) 1992-01-23
US4958044A (en) 1990-09-18
PT91612A (pt) 1990-03-30
FI894121A (fi) 1990-03-02
DK170974B1 (da) 1996-04-09
DK3095A (da) 1995-01-11
PT91612B (pt) 1995-05-31
US4956473A (en) 1990-09-11
DK430689A (da) 1990-03-02

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