DK170666B1 - Substitueret di-t-butylphenol og farmaceutisk præparat deraf og mellemprodukt til fremstilling deraf - Google Patents

Substitueret di-t-butylphenol og farmaceutisk præparat deraf og mellemprodukt til fremstilling deraf Download PDF

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Publication number
DK170666B1
DK170666B1 DK344786A DK344786A DK170666B1 DK 170666 B1 DK170666 B1 DK 170666B1 DK 344786 A DK344786 A DK 344786A DK 344786 A DK344786 A DK 344786A DK 170666 B1 DK170666 B1 DK 170666B1
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Prior art keywords
carbon
tert
butyl
mixture
formula
Prior art date
Application number
DK344786A
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Danish (da)
English (en)
Other versions
DK344786D0 (da
DK344786A (da
Inventor
Robert Allan Scherrer
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of DK344786D0 publication Critical patent/DK344786D0/da
Publication of DK344786A publication Critical patent/DK344786A/da
Application granted granted Critical
Publication of DK170666B1 publication Critical patent/DK170666B1/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK344786A 1985-07-22 1986-07-21 Substitueret di-t-butylphenol og farmaceutisk præparat deraf og mellemprodukt til fremstilling deraf DK170666B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75735885A 1985-07-22 1985-07-22
US75735885 1985-07-22

Publications (3)

Publication Number Publication Date
DK344786D0 DK344786D0 (da) 1986-07-21
DK344786A DK344786A (da) 1987-01-23
DK170666B1 true DK170666B1 (da) 1995-11-27

Family

ID=25047508

Family Applications (1)

Application Number Title Priority Date Filing Date
DK344786A DK170666B1 (da) 1985-07-22 1986-07-21 Substitueret di-t-butylphenol og farmaceutisk præparat deraf og mellemprodukt til fremstilling deraf

Country Status (14)

Country Link
US (5) US5347036A (fr)
EP (1) EP0212848B1 (fr)
JP (2) JPH0667884B2 (fr)
KR (1) KR900007271B1 (fr)
AU (1) AU585626B2 (fr)
CA (2) CA1283419C (fr)
CS (1) CS417691A3 (fr)
DE (1) DE3676008D1 (fr)
DK (1) DK170666B1 (fr)
ES (1) ES2000368A6 (fr)
IL (1) IL79376A (fr)
NO (1) NO172230C (fr)
NZ (1) NZ216854A (fr)
ZA (1) ZA865090B (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868183A (en) * 1986-07-21 1989-09-19 Otsuka Pharmaceutical Factory, Inc. N-pyrazinyl substituted P-aminophenols
JPH0610174B2 (ja) * 1986-09-29 1994-02-09 株式会社大塚製薬工場 アミノフエノ−ル誘導体
JPS63185923A (ja) * 1987-01-28 1988-08-01 Otsuka Pharmaceut Factory Inc 抗炎症剤
JPS63185924A (ja) * 1987-01-28 1988-08-01 Otsuka Pharmaceut Factory Inc リポキシゲナ−ゼ阻害剤
ZA882251B (en) * 1987-04-06 1989-11-29 Riker Laboratories Inc Substituted di-t-butylphenols
NZ226621A (en) * 1987-11-13 1991-12-23 Riker Laboratories Inc Di-tert butyl phenols substituted by alkoxy, benzyloxy, or benzylthio groups; pharmaceutical compositions containing them
AU633263B2 (en) * 1988-07-25 1993-01-28 Libbey-Owens-Ford Co. Sputtered multi-layer color compatible solar control coating
JP2824387B2 (ja) * 1994-03-18 1998-11-11 関西電力株式会社 ガス中の硫化水素と二酸化炭素を除去する方法
US5578639A (en) * 1994-07-01 1996-11-26 Warner-Lambert Company PLA2 inhibitors and their use for inhibition of intestinal cholesterol absorption
US5684204A (en) * 1995-11-15 1997-11-04 The Procter & Gamble Company Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents
DE19608006A1 (de) * 1996-03-04 1997-09-11 Hoechst Ag Salze von phosphonigen Säuren und deren Verwendung als Flammschutzmittel in Kunststoffen
US6218437B1 (en) * 1996-09-30 2001-04-17 The Regents Of The University Of California Treatment and prevention of hepatic disorders
AU742641B2 (en) * 1998-01-28 2002-01-10 Shionogi & Co., Ltd. Novel tricyclic compound
GB2349880A (en) 1999-05-10 2000-11-15 Secr Defence (Thio)morpholinium salts having SHG activity
EP1127882A1 (fr) 2000-01-25 2001-08-29 Pfizer Products Inc. Composés tétrazoliques comme ligands du récepteur thyroid
FR2818656A1 (fr) * 2000-12-22 2002-06-28 Rhodia Chimie Sa Composition et procede d'inhibition de la polymerisation radicalaire de monomeres aromatiques a insaturation ethylenique
US7479507B2 (en) * 2003-01-14 2009-01-20 Adam Heller Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs
MY141255A (en) * 2003-12-11 2010-03-31 Memory Pharm Corp Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
GB0813403D0 (en) * 2008-07-22 2008-08-27 Lectus Therapeutics Ltd Potassium ion channel modulators & uses thereof

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CH7213A (de) * 1893-07-03 1894-02-15 Mueller Dr Eugen Feldflasche
US3318848A (en) * 1963-06-20 1967-05-09 Celanese Corp Melt hydrolysis of oxymethylene copolymers
US3413313A (en) * 1964-06-18 1968-11-26 Parke Davis & Co Anthranilic acid compounds and methods for their production
US3313848A (en) * 1964-06-18 1967-04-11 Parke Davis & Co Anthranilic acids and derivatives
NL133740C (fr) * 1965-04-08
US3558690A (en) * 1965-04-08 1971-01-26 Gelgy Chemical Corp Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation
US3895063A (en) * 1965-04-08 1975-07-15 Ciba Geigy Corp Substituted Anilino Benzyl Alcohols
CH496667A (de) * 1966-10-07 1970-09-30 Geigy Ag J R Verfahren zur Herstellung von neuen substituierten Phenylessigsäuren
CH478762A (de) * 1966-10-07 1969-09-30 Geigy Ag J R Verfahren zur Herstellung von neuen substituierten Zimtsäuren
US3673243A (en) * 1968-05-08 1972-06-27 Sumitomo Chemical Co Novel process for producing o-anilinophenylaliphatic acid derivatives
US3773936A (en) * 1969-06-25 1973-11-20 Merck & Co Inc Method of treating inflammation with substituted anilino salicylic acids
US3778470A (en) * 1972-08-23 1973-12-11 A Sallman Chemical intermediates for the production of substituted 2-anilinophenylacetic acids and esters
US4070484A (en) * 1973-01-18 1978-01-24 Kissei Pharmaceutical Co., Ltd. Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same
JPS6039262B2 (ja) * 1977-05-11 1985-09-05 ウェルファイド株式会社 第3級ブチルフェノ−ル誘導体
US4172151A (en) 1977-05-16 1979-10-23 Riker Laboratories, Inc. Anti-inflammatory method
JPS55145648A (en) * 1979-05-02 1980-11-13 Hisamitsu Pharmaceut Co Inc New derivative of anthranylic acid
US4496390A (en) * 1980-02-26 1985-01-29 May & Baker Limited N-Phenylpyrazole derivatives
US4496590A (en) * 1983-04-18 1985-01-29 Sterling Drug Inc. Benzyl alcohol derivatives, their preparation and use
US4515980A (en) * 1983-07-11 1985-05-07 Sterling Drug Inc. Substituted aminobenzoates, their preparation and use
US4510139A (en) * 1984-01-06 1985-04-09 Sterling Drug Inc. Substituted aminobenzamides and their use as agents which inhibit lipoxygenase activity
JPS60168175A (ja) * 1984-02-13 1985-08-31 Konishiroku Photo Ind Co Ltd 複写機
US4528392A (en) * 1984-04-18 1985-07-09 American Home Products Corporation Aromatic compounds as antiallergic agents
NO174506B (no) * 1984-10-30 1994-02-07 Usv Pharma Corp Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
US4716178A (en) * 1985-07-22 1987-12-29 Riker Laboratories, Inc. Substituted di-t-butylphenols
ZA865091B (en) 1985-07-22 1988-02-24 Riker Laboratories Inc Substituted di-t-butylphenols
US4714776A (en) * 1985-07-22 1987-12-22 Riker Laboratories, Inc. Antiallergic agents
JPS6229557A (ja) * 1985-07-29 1987-02-07 Otsuka Pharmaceut Factory Inc ジ低級アルキルフエノ−ル誘導体
US4677113A (en) * 1986-04-22 1987-06-30 Riker Laboratories, Inc. Di-t-butylphenols substituted by a thenoyl group
JPH0610174B2 (ja) * 1986-09-29 1994-02-09 株式会社大塚製薬工場 アミノフエノ−ル誘導体
US4710515A (en) * 1987-03-17 1987-12-01 Riker Laboratories, Inc. Substituted biphenyl derivatives

Also Published As

Publication number Publication date
KR900007271B1 (ko) 1990-10-06
KR870001149A (ko) 1987-03-11
NO172230C (no) 1993-06-23
NO862924D0 (no) 1986-07-21
US5498745A (en) 1996-03-12
US5495043A (en) 1996-02-27
IL79376A (en) 1991-05-12
NO862924L (no) 1987-01-23
NO172230B (no) 1993-03-15
JPS6345243A (ja) 1988-02-26
DK344786D0 (da) 1986-07-21
EP0212848A2 (fr) 1987-03-04
EP0212848B1 (fr) 1990-12-05
AU585626B2 (en) 1989-06-22
CS417691A3 (en) 1992-10-14
AU6008586A (en) 1987-01-29
US5416113A (en) 1995-05-16
CA1295336C (fr) 1992-02-04
ZA865090B (en) 1988-02-24
DE3676008D1 (de) 1991-01-17
ES2000368A6 (es) 1988-02-16
IL79376A0 (en) 1986-10-31
DK344786A (da) 1987-01-23
US5527824A (en) 1996-06-18
CA1283419C (fr) 1991-04-23
US5347036A (en) 1994-09-13
JPH0667884B2 (ja) 1994-08-31
NZ216854A (en) 1991-03-26
JP2515486B2 (ja) 1996-07-10
EP0212848A3 (en) 1987-12-16
JPH0753485A (ja) 1995-02-28

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B1 Patent granted (law 1993)
PBP Patent lapsed

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