DK169675B1 - 4-Imidazolylmethyltetrahydrocarbazoloner, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende forbindelserne - Google Patents

4-Imidazolylmethyltetrahydrocarbazoloner, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende forbindelserne Download PDF

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Publication number
DK169675B1
DK169675B1 DK624887A DK624887A DK169675B1 DK 169675 B1 DK169675 B1 DK 169675B1 DK 624887 A DK624887 A DK 624887A DK 624887 A DK624887 A DK 624887A DK 169675 B1 DK169675 B1 DK 169675B1
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DK
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Prior art keywords
methyl
compound
formula
alkyl
compounds
Prior art date
Application number
DK624887A
Other languages
Danish (da)
English (en)
Other versions
DK624887D0 (da
DK624887A (da
Inventor
Ian Harold Coates
John Bradshaw
James Angus Bell
David Cedric Humber
George Blanch Ewan
William Leonard Mitchell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868628473A external-priority patent/GB8628473D0/en
Priority claimed from GB878726537A external-priority patent/GB8726537D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DK624887D0 publication Critical patent/DK624887D0/da
Publication of DK624887A publication Critical patent/DK624887A/da
Application granted granted Critical
Publication of DK169675B1 publication Critical patent/DK169675B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK624887A 1986-11-28 1987-11-27 4-Imidazolylmethyltetrahydrocarbazoloner, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende forbindelserne DK169675B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8628473 1986-11-28
GB868628473A GB8628473D0 (en) 1986-11-28 1986-11-28 Chemical compounds
GB8726537 1987-11-12
GB878726537A GB8726537D0 (en) 1987-11-12 1987-11-12 Tricyclic ketones

Publications (3)

Publication Number Publication Date
DK624887D0 DK624887D0 (da) 1987-11-27
DK624887A DK624887A (da) 1988-05-29
DK169675B1 true DK169675B1 (da) 1995-01-09

Family

ID=26291603

Family Applications (1)

Application Number Title Priority Date Filing Date
DK624887A DK169675B1 (da) 1986-11-28 1987-11-27 4-Imidazolylmethyltetrahydrocarbazoloner, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende forbindelserne

Country Status (24)

Country Link
US (1) US4822881A (enExample)
AT (1) AT396933B (enExample)
AU (1) AU605805B2 (enExample)
BE (1) BE1001004A4 (enExample)
CA (1) CA1326032C (enExample)
CH (1) CH676120A5 (enExample)
CZ (1) CZ404591A3 (enExample)
DE (1) DE3740352A1 (enExample)
DK (1) DK169675B1 (enExample)
ES (1) ES2008360A6 (enExample)
FI (1) FI92062C (enExample)
FR (1) FR2611366B1 (enExample)
GB (1) GB2202530B (enExample)
GR (1) GR871809B (enExample)
HK (1) HK51591A (enExample)
IE (1) IE61510B1 (enExample)
IL (1) IL84635A (enExample)
IT (1) IT1211936B (enExample)
NL (1) NL8702851A (enExample)
NO (1) NO172581C (enExample)
NZ (1) NZ222725A (enExample)
PH (1) PH30436A (enExample)
SE (1) SE467255B (enExample)
SG (1) SG46591G (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
US5202343A (en) * 1986-11-28 1993-04-13 Glaxo Group Limited Tricyclic ketones useful as HT3 -receptor antagonists
GB8812002D0 (en) * 1988-05-20 1988-06-22 Glaxo Group Ltd Chemical compounds
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
US4939144A (en) * 1987-10-22 1990-07-03 Glaxo Group Limited Tricyclic ketone derivatives as 5-HT antagonists
US5116984A (en) * 1988-04-07 1992-05-26 Glaxo Group Limited Imidazole derivatives
DK185489A (da) * 1988-04-22 1989-10-23 Duphar Int Res Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
JPH0256485A (ja) * 1988-04-27 1990-02-26 Glaxo Group Ltd ラクタム誘導体
GB8812636D0 (en) * 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
EP0350129A1 (en) * 1988-07-07 1990-01-10 Duphar International Research B.V New annelated indoleketones with an imidazolylalkyl substituent
NO169714C (no) * 1988-08-02 1992-07-29 Glaxo Group Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive laktamderivater
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
US5008272A (en) * 1988-08-15 1991-04-16 Glaxo Group Limited Lactam derivatives
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
GB8820653D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820651D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
GB8823980D0 (en) * 1988-10-13 1988-11-23 Glaxo Group Ltd Chemical compounds
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
GB8904552D0 (en) 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical process
AU631632B2 (en) 1989-04-21 1992-12-03 Novartis Ag Therapeutic use of 5-ht3 receptor antagonists
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
HU211081B (en) * 1990-12-18 1995-10-30 Sandoz Ag Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
KR100368895B1 (ko) * 2000-03-30 2003-01-24 하나제약 주식회사 1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
ATE356623T1 (de) 2002-01-18 2007-04-15 Aryx Therapeutics 5-ht3-rezeptorantagonisten und verwendungsverfahren
PL2432467T3 (pl) 2009-05-20 2018-07-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Zastosowanie antagonistów receptora 5-ht3 serotoniny w leczeniu zaburzeń przedsionkowych ze zmianami chorobowymi
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740404A (en) * 1969-05-09 1973-06-19 American Cyanamid Co Piperidinomethylenedihydrocarbazolones
US3634420A (en) * 1969-05-09 1972-01-11 American Cyanamid Co 3(morpholinomethyl)-2 3-dihydro-carbazol-4(1h)-ones
GB1365296A (en) * 1970-10-30 1974-08-29 Unilever Ltd Dentifrice compositions
US4176230A (en) * 1977-08-04 1979-11-27 Hoffmann-La Roche Inc. 5-(6-Alkylindol-3-ylmethylene)-1,3-dimethyl-2-(methylimino)-4-imidazolidinones
MC1286A1 (fr) * 1978-11-01 1980-07-22 Wellcome Found Preparation de composes heterocycliques utilisables en pharmacie et de medicaments contenant ces composes
DK151884C (da) * 1979-03-07 1988-06-13 Pfizer Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
IL74165A (en) * 1984-01-25 1988-11-15 Glaxo Group Ltd 1,2,3,9-tetrahydro-3-(1h-imidazole-1-yl methyl)-4h-carbazol-4-one compounds,their preparation and pharmaceutical compositions containing them
EP0191562B1 (en) * 1985-01-23 1991-07-10 Glaxo Group Limited Tetrahydrocarbazolone derivatives
GB8518745D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518743D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process

Also Published As

Publication number Publication date
PH30436A (en) 1997-05-09
CH676120A5 (enExample) 1990-12-14
GB8727835D0 (en) 1987-12-31
AU605805B2 (en) 1991-01-24
IT1211936B (it) 1989-11-08
DK624887D0 (da) 1987-11-27
GB2202530B (en) 1990-04-18
NO172581C (no) 1993-08-11
SE8704746L (sv) 1988-05-29
FI875235A7 (fi) 1988-05-29
IE61510B1 (en) 1994-11-16
AT396933B (de) 1993-12-27
US4822881A (en) 1989-04-18
IT8748642A0 (it) 1987-11-27
IE873232L (en) 1988-05-28
ATA312487A (de) 1993-05-15
DE3740352A1 (de) 1988-06-09
NO172581B (no) 1993-05-03
IL84635A0 (en) 1988-04-29
GR871809B (en) 1988-03-07
HK51591A (en) 1991-07-12
NO874959L (no) 1988-05-30
DK624887A (da) 1988-05-29
BE1001004A4 (fr) 1989-06-06
NL8702851A (nl) 1988-06-16
ES2008360A6 (es) 1989-07-16
IL84635A (en) 1993-01-31
SE467255B (sv) 1992-06-22
NO874959D0 (no) 1987-11-27
FI92062B (fi) 1994-06-15
CA1326032C (en) 1994-01-11
SG46591G (en) 1991-07-26
FR2611366A1 (fr) 1988-09-02
FI92062C (fi) 1994-09-26
GB2202530A (en) 1988-09-28
AU8184587A (en) 1988-06-02
CZ404591A3 (en) 1993-08-11
NZ222725A (en) 1990-08-28
SE8704746D0 (sv) 1987-11-27
FR2611366B1 (fr) 1990-03-16
FI875235A0 (fi) 1987-11-27

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