AU605805B2 - Tricyclic ketones - Google Patents

Tricyclic ketones Download PDF

Info

Publication number
AU605805B2
AU605805B2 AU81845/87A AU8184587A AU605805B2 AU 605805 B2 AU605805 B2 AU 605805B2 AU 81845/87 A AU81845/87 A AU 81845/87A AU 8184587 A AU8184587 A AU 8184587A AU 605805 B2 AU605805 B2 AU 605805B2
Authority
AU
Australia
Prior art keywords
methyl
group
compound
formula
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU81845/87A
Other languages
English (en)
Other versions
AU8184587A (en
Inventor
James Angus Bell
John Bradshaw
Ian Harold Coates
George Blanch Ewan
David Cedric Humber
William Leonard Mitchell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868628473A external-priority patent/GB8628473D0/en
Priority claimed from GB878726537A external-priority patent/GB8726537D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AU8184587A publication Critical patent/AU8184587A/en
Application granted granted Critical
Publication of AU605805B2 publication Critical patent/AU605805B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU81845/87A 1986-11-28 1987-11-27 Tricyclic ketones Ceased AU605805B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8628473 1986-11-28
GB868628473A GB8628473D0 (en) 1986-11-28 1986-11-28 Chemical compounds
GB8726537 1987-11-12
GB878726537A GB8726537D0 (en) 1987-11-12 1987-11-12 Tricyclic ketones

Publications (2)

Publication Number Publication Date
AU8184587A AU8184587A (en) 1988-06-02
AU605805B2 true AU605805B2 (en) 1991-01-24

Family

ID=26291603

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81845/87A Ceased AU605805B2 (en) 1986-11-28 1987-11-27 Tricyclic ketones

Country Status (24)

Country Link
US (1) US4822881A (enExample)
AT (1) AT396933B (enExample)
AU (1) AU605805B2 (enExample)
BE (1) BE1001004A4 (enExample)
CA (1) CA1326032C (enExample)
CH (1) CH676120A5 (enExample)
CZ (1) CZ404591A3 (enExample)
DE (1) DE3740352A1 (enExample)
DK (1) DK169675B1 (enExample)
ES (1) ES2008360A6 (enExample)
FI (1) FI92062C (enExample)
FR (1) FR2611366B1 (enExample)
GB (1) GB2202530B (enExample)
GR (1) GR871809B (enExample)
HK (1) HK51591A (enExample)
IE (1) IE61510B1 (enExample)
IL (1) IL84635A (enExample)
IT (1) IT1211936B (enExample)
NL (1) NL8702851A (enExample)
NO (1) NO172581C (enExample)
NZ (1) NZ222725A (enExample)
PH (1) PH30436A (enExample)
SE (1) SE467255B (enExample)
SG (1) SG46591G (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU633254B2 (en) * 1988-05-20 1993-01-28 Glaxo Group Limited Tricyclic ketones Patent to Lapse

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
US5202343A (en) * 1986-11-28 1993-04-13 Glaxo Group Limited Tricyclic ketones useful as HT3 -receptor antagonists
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
US4939144A (en) * 1987-10-22 1990-07-03 Glaxo Group Limited Tricyclic ketone derivatives as 5-HT antagonists
US5116984A (en) * 1988-04-07 1992-05-26 Glaxo Group Limited Imidazole derivatives
DK185489A (da) * 1988-04-22 1989-10-23 Duphar Int Res Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
JPH0256485A (ja) * 1988-04-27 1990-02-26 Glaxo Group Ltd ラクタム誘導体
GB8812636D0 (en) * 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
EP0350129A1 (en) * 1988-07-07 1990-01-10 Duphar International Research B.V New annelated indoleketones with an imidazolylalkyl substituent
NO169714C (no) * 1988-08-02 1992-07-29 Glaxo Group Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive laktamderivater
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
US5008272A (en) * 1988-08-15 1991-04-16 Glaxo Group Limited Lactam derivatives
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
GB8820653D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820651D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
GB8823980D0 (en) * 1988-10-13 1988-11-23 Glaxo Group Ltd Chemical compounds
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
GB8904552D0 (en) 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical process
AU631632B2 (en) 1989-04-21 1992-12-03 Novartis Ag Therapeutic use of 5-ht3 receptor antagonists
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
HU211081B (en) * 1990-12-18 1995-10-30 Sandoz Ag Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
KR100368895B1 (ko) * 2000-03-30 2003-01-24 하나제약 주식회사 1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
ATE356623T1 (de) 2002-01-18 2007-04-15 Aryx Therapeutics 5-ht3-rezeptorantagonisten und verwendungsverfahren
PL2432467T3 (pl) 2009-05-20 2018-07-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Zastosowanie antagonistów receptora 5-ht3 serotoniny w leczeniu zaburzeń przedsionkowych ze zmianami chorobowymi
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3809785A (en) * 1984-01-25 1985-08-01 Glaxo Group Limited Heterocyclic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740404A (en) * 1969-05-09 1973-06-19 American Cyanamid Co Piperidinomethylenedihydrocarbazolones
US3634420A (en) * 1969-05-09 1972-01-11 American Cyanamid Co 3(morpholinomethyl)-2 3-dihydro-carbazol-4(1h)-ones
GB1365296A (en) * 1970-10-30 1974-08-29 Unilever Ltd Dentifrice compositions
US4176230A (en) * 1977-08-04 1979-11-27 Hoffmann-La Roche Inc. 5-(6-Alkylindol-3-ylmethylene)-1,3-dimethyl-2-(methylimino)-4-imidazolidinones
MC1286A1 (fr) * 1978-11-01 1980-07-22 Wellcome Found Preparation de composes heterocycliques utilisables en pharmacie et de medicaments contenant ces composes
DK151884C (da) * 1979-03-07 1988-06-13 Pfizer Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
EP0191562B1 (en) * 1985-01-23 1991-07-10 Glaxo Group Limited Tetrahydrocarbazolone derivatives
GB8518745D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518743D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3809785A (en) * 1984-01-25 1985-08-01 Glaxo Group Limited Heterocyclic compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU633254B2 (en) * 1988-05-20 1993-01-28 Glaxo Group Limited Tricyclic ketones Patent to Lapse

Also Published As

Publication number Publication date
PH30436A (en) 1997-05-09
CH676120A5 (enExample) 1990-12-14
GB8727835D0 (en) 1987-12-31
IT1211936B (it) 1989-11-08
DK624887D0 (da) 1987-11-27
GB2202530B (en) 1990-04-18
NO172581C (no) 1993-08-11
SE8704746L (sv) 1988-05-29
FI875235A7 (fi) 1988-05-29
IE61510B1 (en) 1994-11-16
AT396933B (de) 1993-12-27
US4822881A (en) 1989-04-18
IT8748642A0 (it) 1987-11-27
DK169675B1 (da) 1995-01-09
IE873232L (en) 1988-05-28
ATA312487A (de) 1993-05-15
DE3740352A1 (de) 1988-06-09
NO172581B (no) 1993-05-03
IL84635A0 (en) 1988-04-29
GR871809B (en) 1988-03-07
HK51591A (en) 1991-07-12
NO874959L (no) 1988-05-30
DK624887A (da) 1988-05-29
BE1001004A4 (fr) 1989-06-06
NL8702851A (nl) 1988-06-16
ES2008360A6 (es) 1989-07-16
IL84635A (en) 1993-01-31
SE467255B (sv) 1992-06-22
NO874959D0 (no) 1987-11-27
FI92062B (fi) 1994-06-15
CA1326032C (en) 1994-01-11
SG46591G (en) 1991-07-26
FR2611366A1 (fr) 1988-09-02
FI92062C (fi) 1994-09-26
GB2202530A (en) 1988-09-28
AU8184587A (en) 1988-06-02
CZ404591A3 (en) 1993-08-11
NZ222725A (en) 1990-08-28
SE8704746D0 (sv) 1987-11-27
FR2611366B1 (fr) 1990-03-16
FI875235A0 (fi) 1987-11-27

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