SE8704746L - Tricykliska ketoner - Google Patents

Tricykliska ketoner

Info

Publication number
SE8704746L
SE8704746L SE8704746A SE8704746A SE8704746L SE 8704746 L SE8704746 L SE 8704746L SE 8704746 A SE8704746 A SE 8704746A SE 8704746 A SE8704746 A SE 8704746A SE 8704746 L SE8704746 L SE 8704746L
Authority
SE
Sweden
Prior art keywords
ketons
tricyclic
compounds
image
formula
Prior art date
Application number
SE8704746A
Other languages
English (en)
Other versions
SE8704746D0 (sv
SE467255B (sv
Inventor
I H Coates
J Bradshaw
J A Bell
D C Humber
G B Ewan
W L Mitchell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868628473A external-priority patent/GB8628473D0/en
Priority claimed from GB878726537A external-priority patent/GB8726537D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE8704746D0 publication Critical patent/SE8704746D0/sv
Publication of SE8704746L publication Critical patent/SE8704746L/sv
Publication of SE467255B publication Critical patent/SE467255B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8704746A 1986-11-28 1987-11-27 3-imidazolylmetyl-4-karbazoloner, 3-imidazolylmetylen-4-karbazoloner och mellanprodukter SE467255B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868628473A GB8628473D0 (en) 1986-11-28 1986-11-28 Chemical compounds
GB878726537A GB8726537D0 (en) 1987-11-12 1987-11-12 Tricyclic ketones

Publications (3)

Publication Number Publication Date
SE8704746D0 SE8704746D0 (sv) 1987-11-27
SE8704746L true SE8704746L (sv) 1988-05-29
SE467255B SE467255B (sv) 1992-06-22

Family

ID=26291603

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8704746A SE467255B (sv) 1986-11-28 1987-11-27 3-imidazolylmetyl-4-karbazoloner, 3-imidazolylmetylen-4-karbazoloner och mellanprodukter

Country Status (24)

Country Link
US (1) US4822881A (sv)
AT (1) AT396933B (sv)
AU (1) AU605805B2 (sv)
BE (1) BE1001004A4 (sv)
CA (1) CA1326032C (sv)
CH (1) CH676120A5 (sv)
CZ (1) CZ404591A3 (sv)
DE (1) DE3740352A1 (sv)
DK (1) DK169675B1 (sv)
ES (1) ES2008360A6 (sv)
FI (1) FI92062C (sv)
FR (1) FR2611366B1 (sv)
GB (1) GB2202530B (sv)
GR (1) GR871809B (sv)
HK (1) HK51591A (sv)
IE (1) IE61510B1 (sv)
IL (1) IL84635A (sv)
IT (1) IT1211936B (sv)
NL (1) NL8702851A (sv)
NO (1) NO172581C (sv)
NZ (1) NZ222725A (sv)
PH (1) PH30436A (sv)
SE (1) SE467255B (sv)
SG (1) SG46591G (sv)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8812002D0 (en) * 1988-05-20 1988-06-22 Glaxo Group Ltd Chemical compounds
US5202343A (en) * 1986-11-28 1993-04-13 Glaxo Group Limited Tricyclic ketones useful as HT3 -receptor antagonists
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
US4939144A (en) * 1987-10-22 1990-07-03 Glaxo Group Limited Tricyclic ketone derivatives as 5-HT antagonists
JPH0249772A (ja) * 1988-04-07 1990-02-20 Glaxo Group Ltd イミダゾール誘導体
DK185489A (da) * 1988-04-22 1989-10-23 Duphar Int Res Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
JPH0256485A (ja) * 1988-04-27 1990-02-26 Glaxo Group Ltd ラクタム誘導体
GB8812636D0 (en) * 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
EP0350129A1 (en) * 1988-07-07 1990-01-10 Duphar International Research B.V New annelated indoleketones with an imidazolylalkyl substituent
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
ES2088389T3 (es) * 1988-08-02 1996-08-16 Glaxo Group Ltd Derivados de lactamas.
US5008272A (en) * 1988-08-15 1991-04-16 Glaxo Group Limited Lactam derivatives
GB8820651D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
EP0357417A1 (en) * 1988-09-01 1990-03-07 Glaxo Group Limited Lactam derivatives
GB8820653D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
GB8823980D0 (en) * 1988-10-13 1988-11-23 Glaxo Group Ltd Chemical compounds
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
HU204049B (en) * 1989-02-28 1991-11-28 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising same
GB8904552D0 (en) 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical process
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
DK0422154T3 (da) 1989-04-21 1994-03-07 Sandoz Ag Terapeutisk anvendelse af 5-HT3-receptorantagonister
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments
HU211081B (en) * 1990-12-18 1995-10-30 Sandoz Ag Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
KR100368895B1 (ko) * 2000-03-30 2003-01-24 하나제약 주식회사 1,2,3,9-테트라하이드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온의 제조방법
CA2473392A1 (en) * 2002-01-18 2003-07-31 Aryx Therapeutics 5-ht3 receptor antagonists and methods of use
DK2432467T3 (en) 2009-05-20 2018-04-16 Inst Nat Sante Rech Med SEROTONIN 5-HT3 RECEPTOR ANTAGONISTS FOR USE IN TREATMENT OF VESTIBULAR DAMAGE LESSONS
ES2432618T3 (es) 2009-05-20 2013-12-04 Inserm (Institut National De La Santé Et De La Recherche Medicale) Antagonistas del receptor 5-HT3 de serotonina para usar en el tratamiento o prevención de una patología del oído interno con déficit vestibular

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740404A (en) * 1969-05-09 1973-06-19 American Cyanamid Co Piperidinomethylenedihydrocarbazolones
US3634420A (en) * 1969-05-09 1972-01-11 American Cyanamid Co 3(morpholinomethyl)-2 3-dihydro-carbazol-4(1h)-ones
GB1365296A (en) * 1970-10-30 1974-08-29 Unilever Ltd Dentifrice compositions
US4176230A (en) * 1977-08-04 1979-11-27 Hoffmann-La Roche Inc. 5-(6-Alkylindol-3-ylmethylene)-1,3-dimethyl-2-(methylimino)-4-imidazolidinones
EP0012208B1 (en) * 1978-11-01 1983-01-26 The Wellcome Foundation Limited 9-(3-(3,5-cis-dimethylpiperazino)propyl)-carbazole, its preparation and pharmaceutical compositions containing it
DK151884C (da) * 1979-03-07 1988-06-13 Pfizer Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf
KR920003064B1 (ko) * 1984-01-25 1992-04-13 글락소 그룹 리미티드 헤테로시클릭 화합물의 제조방법
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
DE3680123D1 (en) * 1985-01-23 1991-08-14 Glaxo Group Ltd Tetrahydrocarbazolonderivate.
GB8518745D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518743D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process

Also Published As

Publication number Publication date
NL8702851A (nl) 1988-06-16
AU8184587A (en) 1988-06-02
IE873232L (en) 1988-05-28
FI875235A (sv) 1988-05-29
IE61510B1 (en) 1994-11-16
GB2202530B (en) 1990-04-18
GR871809B (en) 1988-03-07
DK624887A (da) 1988-05-29
HK51591A (en) 1991-07-12
SE8704746D0 (sv) 1987-11-27
IL84635A (en) 1993-01-31
FI92062C (sv) 1994-09-26
PH30436A (en) 1997-05-09
DK169675B1 (da) 1995-01-09
NO874959D0 (no) 1987-11-27
FI875235A0 (sv) 1987-11-27
NO172581B (no) 1993-05-03
ES2008360A6 (es) 1989-07-16
FI92062B (sv) 1994-06-15
SE467255B (sv) 1992-06-22
CA1326032C (en) 1994-01-11
BE1001004A4 (fr) 1989-06-06
US4822881A (en) 1989-04-18
NO172581C (no) 1993-08-11
DK624887D0 (da) 1987-11-27
FR2611366B1 (fr) 1990-03-16
GB2202530A (en) 1988-09-28
AT396933B (de) 1993-12-27
ATA312487A (de) 1993-05-15
CH676120A5 (sv) 1990-12-14
FR2611366A1 (fr) 1988-09-02
AU605805B2 (en) 1991-01-24
NZ222725A (en) 1990-08-28
CZ404591A3 (en) 1993-08-11
GB8727835D0 (en) 1987-12-31
IL84635A0 (en) 1988-04-29
DE3740352A1 (de) 1988-06-09
IT8748642A0 (it) 1987-11-27
SG46591G (en) 1991-07-26
NO874959L (no) 1988-05-30
IT1211936B (it) 1989-11-08

Similar Documents

Publication Publication Date Title
SE8704746D0 (sv) Tricykliska ketoner
EA199700156A1 (ru) Производные индола как антагонисты рецептора 5-нт
ES8609309A1 (es) Un nuevo procedimiento para la preparacion de nuevos derivados. de carbazolona.
ES2123149T3 (es) Derivados de perhidroisoindol como antagonistas de la substancia p.
FI931370A0 (fi) Kvaeve innehaollande analoger av icke-aromatiska heterocykliska foereningar med en fusionerad ring
DE3684195D1 (de) Substituierte imidazolylmethyltetrahydrocarbazolone.
ES2060655T3 (es) Derivados de lactamas.
DE3685471D1 (de) Tetrahydrocarbazolonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
YU128091A (sh) Derivati hinuklidina
ES533338A0 (es) Derivados de la 2-pirimidinil-1-piperazina
NO964236L (no) Anvendelse av serotonin-antagonister (5HT3) for behandling av fibromyalgi
EP0339959A3 (en) Lactam derivatives
EP0266899A3 (en) Indole derivatives
NO871861D0 (no) Fremgangsmaate for fremstilling av nye dopamin beta-hydroxylase inhibitorer.
ES2000936A6 (es) Un procedimiento para la preparacion de 3-imidazolin -metiltetrahidrocarbazolonas.
EP0356098A3 (en) Lactam derivatives
ATE130603T1 (de) Oxalon und hypotensive 2-decarboxyl-2 azylthioalkyl prostagladin-derivate.
EP0327307A3 (en) Tricyclic ketone derivatives having a 5-HT3 antagonist activity
ES2143630T3 (es) Derivados azabicicloalquilos de imidazo(1,5-a)indol-3-ona utilizados como antagonistas de 5ht3.
DE3872722D1 (de) Indol-derivate.
EA199900043A1 (ru) ПРОИЗВОДНЫЕ ПИРИДИЛКАРБАМОИЛИНДОЛИНОВ В КАЧЕСТВЕ АНТАГОНИСТОВ 5-НТ2с-РЕЦЕПТОРОВ
DK245789D0 (da) Tricycliske ketoner
DK0521766T3 (da) Hidtil ukendt fremgangsmåde til syntese af enantiomerer af 3-aminochromanderivater
ATE26275T1 (de) Acridanon-derivate.
MY103831A (en) Lactam derivatives.

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8704746-0

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8704746-0

Format of ref document f/p: F