ATE130603T1 - Oxalon und hypotensive 2-decarboxyl-2 azylthioalkyl prostagladin-derivate. - Google Patents

Oxalon und hypotensive 2-decarboxyl-2 azylthioalkyl prostagladin-derivate.

Info

Publication number
ATE130603T1
ATE130603T1 AT92913037T AT92913037T ATE130603T1 AT E130603 T1 ATE130603 T1 AT E130603T1 AT 92913037 T AT92913037 T AT 92913037T AT 92913037 T AT92913037 T AT 92913037T AT E130603 T1 ATE130603 T1 AT E130603T1
Authority
AT
Austria
Prior art keywords
decarboxyl
azylthioalkyl
oxalone
prostagladin
hypotensive
Prior art date
Application number
AT92913037T
Other languages
English (en)
Inventor
Ming Fai Chan
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of ATE130603T1 publication Critical patent/ATE130603T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT92913037T 1991-05-17 1992-05-13 Oxalon und hypotensive 2-decarboxyl-2 azylthioalkyl prostagladin-derivate. ATE130603T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/702,220 US5312832A (en) 1991-05-17 1991-05-17 Ocular hypotensive 2-decarboxyl-2-acylthioalkyl prostaglandin derivatives

Publications (1)

Publication Number Publication Date
ATE130603T1 true ATE130603T1 (de) 1995-12-15

Family

ID=24820309

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92913037T ATE130603T1 (de) 1991-05-17 1992-05-13 Oxalon und hypotensive 2-decarboxyl-2 azylthioalkyl prostagladin-derivate.

Country Status (10)

Country Link
US (1) US5312832A (de)
EP (1) EP0585380B1 (de)
JP (1) JPH06507897A (de)
AT (1) ATE130603T1 (de)
AU (1) AU653240B2 (de)
CA (1) CA2102295A1 (de)
DE (1) DE69206262T2 (de)
ES (1) ES2079872T3 (de)
HU (1) HUT65913A (de)
WO (1) WO1992020648A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5312842A (en) * 1992-10-30 1994-05-17 Allergan, Inc. Cyclopentane heptenylsulfinylalkyl and heptanylsulfinylalkyl-2-aliphatic or aryl aliphatic derivatives
US5516796A (en) * 1994-03-24 1996-05-14 Kabi Pharmacia Ab Thioprostaglandins and -prostaglandin-like compounds and therapeutic uses thereof
JP4834224B2 (ja) 1999-03-05 2011-12-14 デューク ユニバーシティ Ｃ１６不飽和ｆｐ−選択的プロスタグランジン類縁体
DE60003435T2 (de) 1999-08-04 2004-05-19 The Procter & Gamble Company, Cincinnati Neue 2-decarboxy-2-phosphinico prostaglandin f analoge
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
WO2007093839A1 (en) * 2006-02-16 2007-08-23 Sederma New polypeptides kxk and their use
US8722739B2 (en) * 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605381A (nl) * 1975-05-26 1976-11-30 Schering Ag Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking.
JPS5334747A (en) * 1976-09-14 1978-03-31 Ono Pharmaceut Co Ltd Prostaglandin-like compounds and their preparation
EP0051284B1 (de) * 1980-10-31 1985-01-09 Teijin Limited Thiaprostaglandin E1-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
US5238961A (en) * 1990-06-14 1993-08-24 Allergan, Inc. Pgf 1-alcohols and their use as ocular hypotensives

Also Published As

Publication number Publication date
AU2006692A (en) 1992-12-30
DE69206262T2 (de) 1996-07-18
DE69206262D1 (de) 1996-01-04
HUT65913A (en) 1994-07-28
AU653240B2 (en) 1994-09-22
US5312832A (en) 1994-05-17
EP0585380B1 (de) 1995-11-22
EP0585380A1 (de) 1994-03-09
ES2079872T3 (es) 1996-01-16
CA2102295A1 (en) 1992-11-18
WO1992020648A1 (en) 1992-11-26
JPH06507897A (ja) 1994-09-08

Similar Documents

Publication Publication Date Title
ATE269290T1 (de) Benzoylderivate
ES2138691T3 (es) Procedimiento para la obtencion de derivados de n-acil-5-fluorocitidina.
ES533338A0 (es) Derivados de la 2-pirimidinil-1-piperazina
ATE158506T1 (de) Okulare hypotensive 2-dekarboxyl-2-aminoalkyl- prostaglandine
ATE130603T1 (de) Oxalon und hypotensive 2-decarboxyl-2 azylthioalkyl prostagladin-derivate.
SE8703854D0 (sv) Prostaglandinderivat for behandling av glaukom eller okuler hypertension
CO4230097A1 (es) Piridopirimidinas sustituidas como antihipertensivos
ES2164366T3 (es) Derivados de la distamicina acriloil sustituidos, procedimiento de fabricacion asociado y su utilizacion como agentes antitumorales y antivirales.
MX9305093A (es) Nuevos derivadosindano-2 mercaptoacetilamina triciclicos 2-sustituidos, utiles como inhibidores de la encefalinasa.
ES2096941T3 (es) 27-hidroxirrapamicina y derivados de la misma.
FI892222A (fi) Peptidalkoholer med antikoagulantverkan.
ATE73768T1 (de) 2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8inter-m-phenylene-pgi2-derivate.
ES2060944T3 (es) Derivados de 2,5,6,7-tetranor-4,8-inter-m-fenileno de pgi2 (prostaglandina i2).
TR200001080T2 (tr) 2 ile ikame edilmiş 1,2-Benisotiyazol türevleri ve bunların serrotonın antagonistleri
WO1992010473A3 (en) 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives
ATE164763T1 (de) Okulare hypotensive homo-prostaglandinderivate
NO921317D0 (no) Antimetastatisk virkende midler
ATE176242T1 (de) Uck14-verbindungen
FR2401136A1 (fr) Derives de type isothio-uree
AR241135A2 (es) "derivados de n-triazinil-n-sulfamoilurea herbicidamente activos y formulacion herbicida que los contiene".
IT1249649B (it) Derivato liposolubile dell'alfa-tocoferolo

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties