ES2079872T3 - Derivados hipotensores oculares de la 2-descarboxil-2-aciltioalquilprostaglandina. - Google Patents
Derivados hipotensores oculares de la 2-descarboxil-2-aciltioalquilprostaglandina.Info
- Publication number
- ES2079872T3 ES2079872T3 ES92913037T ES92913037T ES2079872T3 ES 2079872 T3 ES2079872 T3 ES 2079872T3 ES 92913037 T ES92913037 T ES 92913037T ES 92913037 T ES92913037 T ES 92913037T ES 2079872 T3 ES2079872 T3 ES 2079872T3
- Authority
- ES
- Spain
- Prior art keywords
- descarboxil
- aciltioalquilprostaglandina
- derivatives
- hypotensive
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000001953 Hypotension Diseases 0.000 title 1
- 208000021822 hypotensive Diseases 0.000 title 1
- 230000001077 hypotensive effect Effects 0.000 title 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A PROSTAGLANDINAS DE 2DECARBOXIL-2-ACILTIOALQUILO QUE SON HIPOTENSOS OCULARES POTENTES, Y SON PARTICULARES CONVENIENTES PARA EL MANEJO DE GLAUCOMA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/702,220 US5312832A (en) | 1991-05-17 | 1991-05-17 | Ocular hypotensive 2-decarboxyl-2-acylthioalkyl prostaglandin derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2079872T3 true ES2079872T3 (es) | 1996-01-16 |
Family
ID=24820309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92913037T Expired - Lifetime ES2079872T3 (es) | 1991-05-17 | 1992-05-13 | Derivados hipotensores oculares de la 2-descarboxil-2-aciltioalquilprostaglandina. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5312832A (es) |
EP (1) | EP0585380B1 (es) |
JP (1) | JPH06507897A (es) |
AT (1) | ATE130603T1 (es) |
AU (1) | AU653240B2 (es) |
CA (1) | CA2102295A1 (es) |
DE (1) | DE69206262T2 (es) |
ES (1) | ES2079872T3 (es) |
HU (1) | HUT65913A (es) |
WO (1) | WO1992020648A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5312842A (en) * | 1992-10-30 | 1994-05-17 | Allergan, Inc. | Cyclopentane heptenylsulfinylalkyl and heptanylsulfinylalkyl-2-aliphatic or aryl aliphatic derivatives |
US5516796A (en) * | 1994-03-24 | 1996-05-14 | Kabi Pharmacia Ab | Thioprostaglandins and -prostaglandin-like compounds and therapeutic uses thereof |
JP4834224B2 (ja) | 1999-03-05 | 2011-12-14 | デューク ユニバーシティ | C16不飽和fp−選択的プロスタグランジン類縁体 |
DE60003435T2 (de) | 1999-08-04 | 2004-05-19 | The Procter & Gamble Company, Cincinnati | Neue 2-decarboxy-2-phosphinico prostaglandin f analoge |
US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
US20020146439A1 (en) * | 2000-03-31 | 2002-10-10 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins |
US20020037914A1 (en) | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
WO2007093839A1 (en) * | 2006-02-16 | 2007-08-23 | Sederma | New polypeptides kxk and their use |
US8722739B2 (en) * | 2008-10-29 | 2014-05-13 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
US8623918B2 (en) * | 2008-10-29 | 2014-01-07 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7605381A (nl) * | 1975-05-26 | 1976-11-30 | Schering Ag | Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking. |
JPS5334747A (en) * | 1976-09-14 | 1978-03-31 | Ono Pharmaceut Co Ltd | Prostaglandin-like compounds and their preparation |
EP0051284B1 (en) * | 1980-10-31 | 1985-01-09 | Teijin Limited | Novel thiaprostaglandin e1 derivatives, process for production thereof, and pharmaceuticals containing these compounds |
US5238961A (en) * | 1990-06-14 | 1993-08-24 | Allergan, Inc. | Pgf 1-alcohols and their use as ocular hypotensives |
-
1991
- 1991-05-17 US US07/702,220 patent/US5312832A/en not_active Expired - Fee Related
-
1992
- 1992-05-13 AT AT92913037T patent/ATE130603T1/de not_active IP Right Cessation
- 1992-05-13 WO PCT/US1992/003969 patent/WO1992020648A1/en active IP Right Grant
- 1992-05-13 ES ES92913037T patent/ES2079872T3/es not_active Expired - Lifetime
- 1992-05-13 DE DE69206262T patent/DE69206262T2/de not_active Expired - Fee Related
- 1992-05-13 HU HU9303242A patent/HUT65913A/hu unknown
- 1992-05-13 JP JP5500151A patent/JPH06507897A/ja active Pending
- 1992-05-13 AU AU20066/92A patent/AU653240B2/en not_active Ceased
- 1992-05-13 EP EP92913037A patent/EP0585380B1/en not_active Expired - Lifetime
- 1992-05-13 CA CA002102295A patent/CA2102295A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2006692A (en) | 1992-12-30 |
DE69206262T2 (de) | 1996-07-18 |
DE69206262D1 (de) | 1996-01-04 |
HUT65913A (en) | 1994-07-28 |
AU653240B2 (en) | 1994-09-22 |
US5312832A (en) | 1994-05-17 |
EP0585380B1 (en) | 1995-11-22 |
EP0585380A1 (en) | 1994-03-09 |
CA2102295A1 (en) | 1992-11-18 |
WO1992020648A1 (en) | 1992-11-26 |
ATE130603T1 (de) | 1995-12-15 |
JPH06507897A (ja) | 1994-09-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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