ES2139934T3 - Procedimiento mejorado para preparar derivados de cadena lateral de ciclohexapeptidil lipopeptidos. - Google Patents
Procedimiento mejorado para preparar derivados de cadena lateral de ciclohexapeptidil lipopeptidos.Info
- Publication number
- ES2139934T3 ES2139934T3 ES95930199T ES95930199T ES2139934T3 ES 2139934 T3 ES2139934 T3 ES 2139934T3 ES 95930199 T ES95930199 T ES 95930199T ES 95930199 T ES95930199 T ES 95930199T ES 2139934 T3 ES2139934 T3 ES 2139934T3
- Authority
- ES
- Spain
- Prior art keywords
- lipopeptides
- side chain
- cyclohexapeptidil
- chain derivatives
- improved procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE DESCRIBE UN PROCEDIMIENTO MEJORADO DE PREPARACION DE DERIVADOS DE CADENAS LATERALES DE LIPOPEPTIDOS DE CICLOHEXAPEPTIDILO, REPRESENTADOS POR LA FORMULA SEQ ID NO. 1, DONDE R{SUP,1} SE DESCRIBE TOTALMENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29517694A | 1994-08-23 | 1994-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2139934T3 true ES2139934T3 (es) | 2000-02-16 |
Family
ID=23136562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95930199T Expired - Lifetime ES2139934T3 (es) | 1994-08-23 | 1995-08-18 | Procedimiento mejorado para preparar derivados de cadena lateral de ciclohexapeptidil lipopeptidos. |
Country Status (11)
Country | Link |
---|---|
US (2) | US5684128A (es) |
EP (1) | EP0779895B1 (es) |
JP (1) | JP3118466B2 (es) |
AT (1) | ATE186737T1 (es) |
AU (1) | AU692043B2 (es) |
CA (1) | CA2195975C (es) |
DE (1) | DE69513408T2 (es) |
DK (1) | DK0779895T3 (es) |
ES (1) | ES2139934T3 (es) |
GR (1) | GR3032427T3 (es) |
WO (1) | WO1996006109A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE223226T1 (de) * | 1994-09-16 | 2002-09-15 | Merck & Co Inc | Azazyklohexapeptid-verbindungen |
US5552521A (en) * | 1995-02-10 | 1996-09-03 | Merck & Co., Inc. | Process for preparing certain aza cyclohexapeptides |
US6080719A (en) * | 1996-02-23 | 2000-06-27 | Hoechst Aktiengesellschaft | Cyclohexapeptides and their mixtures, a process for preparing them, and their use |
US5696084A (en) * | 1996-08-16 | 1997-12-09 | Abbott Laboratories | Amino-lipopetide antifungal agents |
DE69934683T2 (de) * | 1998-04-23 | 2007-10-18 | Aventis Pharma Deutschland Gmbh | Verfahren zur reduzierung von echinocandin-peptiden zu deren c4-monodeoxyhomotyrosin analoga |
EP1785432A1 (en) * | 2005-11-15 | 2007-05-16 | Sandoz AG | Process and intermediates for the synthesis of caspofungin. |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE851310A (fr) * | 1976-02-12 | 1977-08-10 | Sandoz Sa | Nouveaux derives de la tetrahydro-equinocandine b |
DE2742435A1 (de) * | 1976-09-28 | 1978-04-06 | Sandoz Ag | Aminoalkylaether der peptide tetrahydro- sl 7810/f-ii, s 31794/f-1, aculeacin a und tetrahydroechinocandin b, ihre verwendung und herstellung |
US5166135A (en) * | 1988-09-12 | 1992-11-24 | Merck & Company, Inc. | Method for the control of pneumocystis carinii |
US5194377A (en) * | 1989-06-30 | 1993-03-16 | Merck & Co., Inc. | Antibiotic agent |
US5202309A (en) * | 1989-06-30 | 1993-04-13 | Merck & Co., Inc. | Antibiotic cyclopeptide fermentation product |
US5310873A (en) * | 1990-03-12 | 1994-05-10 | Merck & Co., Inc. | Cyclohexapeptide compound |
US5159059A (en) * | 1990-05-29 | 1992-10-27 | Merck & Co., Inc. | Process for reduction of certain cyclohexapeptide compounds |
EP0486011A3 (en) * | 1990-11-16 | 1992-07-15 | Fujisawa Pharmaceutical Co., Ltd. | Pharmaceutical composition against pneumocystis carinii |
ATE140460T1 (de) * | 1991-10-17 | 1996-08-15 | Merck & Co Inc | Echinocandin-b-derivat |
WO1994009033A1 (en) * | 1992-10-16 | 1994-04-28 | Merck & Co., Inc. | An improved process for cyclohexapeptidyl bisamine compounds |
US5378804A (en) * | 1993-03-16 | 1995-01-03 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
ATE223226T1 (de) * | 1994-09-16 | 2002-09-15 | Merck & Co Inc | Azazyklohexapeptid-verbindungen |
US5516756A (en) * | 1994-10-31 | 1996-05-14 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
US5552521A (en) * | 1995-02-10 | 1996-09-03 | Merck & Co., Inc. | Process for preparing certain aza cyclohexapeptides |
-
1995
- 1995-08-18 AU AU44656/96A patent/AU692043B2/en not_active Ceased
- 1995-08-18 CA CA002195975A patent/CA2195975C/en not_active Expired - Fee Related
- 1995-08-18 AT AT95930199T patent/ATE186737T1/de not_active IP Right Cessation
- 1995-08-18 ES ES95930199T patent/ES2139934T3/es not_active Expired - Lifetime
- 1995-08-18 DK DK95930199T patent/DK0779895T3/da active
- 1995-08-18 JP JP08508206A patent/JP3118466B2/ja not_active Expired - Fee Related
- 1995-08-18 DE DE69513408T patent/DE69513408T2/de not_active Expired - Fee Related
- 1995-08-18 EP EP95930199A patent/EP0779895B1/en not_active Expired - Lifetime
- 1995-08-18 WO PCT/US1995/010506 patent/WO1996006109A1/en active IP Right Grant
-
1996
- 1996-02-20 US US08/604,135 patent/US5684128A/en not_active Expired - Fee Related
- 1996-05-16 US US08/648,741 patent/US5646245A/en not_active Expired - Fee Related
-
2000
- 2000-01-19 GR GR20000400124T patent/GR3032427T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5646245A (en) | 1997-07-08 |
EP0779895B1 (en) | 1999-11-17 |
WO1996006109A1 (en) | 1996-02-29 |
JPH10500141A (ja) | 1998-01-06 |
ATE186737T1 (de) | 1999-12-15 |
AU4465696A (en) | 1996-03-14 |
CA2195975A1 (en) | 1996-02-29 |
CA2195975C (en) | 2001-05-15 |
GR3032427T3 (en) | 2000-05-31 |
AU692043B2 (en) | 1998-05-28 |
EP0779895A4 (en) | 1997-10-29 |
JP3118466B2 (ja) | 2000-12-18 |
DE69513408D1 (de) | 1999-12-23 |
DK0779895T3 (da) | 2000-03-13 |
US5684128A (en) | 1997-11-04 |
EP0779895A1 (en) | 1997-06-25 |
DE69513408T2 (de) | 2000-06-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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