BR9711477A - Derivado de benzocicloheptapiridina substituida Úteis para inibi-Æo de transferase de farnesila - Google Patents

Derivado de benzocicloheptapiridina substituida Úteis para inibi-Æo de transferase de farnesila

Info

Publication number
BR9711477A
BR9711477A BR9711477A BR9711477A BR9711477A BR 9711477 A BR9711477 A BR 9711477A BR 9711477 A BR9711477 A BR 9711477A BR 9711477 A BR9711477 A BR 9711477A BR 9711477 A BR9711477 A BR 9711477A
Authority
BR
Brazil
Prior art keywords
farnesyl transferase
inhibiting farnesyl
derivative useful
benzocycloheptapyridine
substituted
Prior art date
Application number
BR9711477A
Other languages
English (en)
Inventor
Arthur G Taveras
George F N Joroge
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of BR9711477A publication Critical patent/BR9711477A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Confectionery (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Indole Compounds (AREA)
BR9711477A 1996-09-13 1997-09-11 Derivado de benzocicloheptapiridina substituida Úteis para inibi-Æo de transferase de farnesila BR9711477A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71192596A 1996-09-13 1996-09-13
PCT/US1997/015905 WO1998011099A1 (en) 1996-09-13 1997-09-11 Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase

Publications (1)

Publication Number Publication Date
BR9711477A true BR9711477A (pt) 1999-08-24

Family

ID=24860067

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9711477A BR9711477A (pt) 1996-09-13 1997-09-11 Derivado de benzocicloheptapiridina substituida Úteis para inibi-Æo de transferase de farnesila

Country Status (21)

Country Link
EP (1) EP0931079B1 (pt)
JP (1) JP2001500508A (pt)
KR (1) KR20000036103A (pt)
CN (1) CN1122031C (pt)
AT (1) ATE209201T1 (pt)
AU (1) AU4337797A (pt)
BR (1) BR9711477A (pt)
CA (1) CA2264513C (pt)
CZ (1) CZ87499A3 (pt)
DE (1) DE69709774T2 (pt)
ES (1) ES2163195T3 (pt)
HK (1) HK1018443A1 (pt)
HU (1) HUP9904056A3 (pt)
ID (1) ID22156A (pt)
IL (1) IL128929A0 (pt)
NO (1) NO991229L (pt)
NZ (1) NZ334437A (pt)
PL (1) PL332253A1 (pt)
SK (1) SK33599A3 (pt)
TR (1) TR199901205T2 (pt)
WO (1) WO1998011099A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0989979A1 (en) * 1997-06-17 2000-04-05 Schering Corporation Novel n-substituted urea inhibitors of farnesyl-protein transferase
US6358968B1 (en) 1997-06-17 2002-03-19 Schering Corporation N-substituted urea inhibitors of farnesyl-protein transferase
US6509346B2 (en) 1998-01-21 2003-01-21 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
JP2002501052A (ja) 1998-01-21 2002-01-15 ミレニアム・ファーマシューティカルズ・インコーポレイテッド ケモカイン受容体アンタゴニストおよびその使用方法
US6613905B1 (en) 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
WO1999037651A1 (en) 1998-01-21 1999-07-29 Millenium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6288083B1 (en) 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7271176B2 (en) 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US6503926B2 (en) 1998-09-04 2003-01-07 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
US5719148A (en) * 1993-10-15 1998-02-17 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
IL125062A (en) * 1995-12-22 2003-11-23 Schering Corp Tricyclic amides and pharmaceutical compositions containing them for inhibition of g-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
CN1236364A (zh) 1999-11-24
ID22156A (id) 1999-09-09
HUP9904056A3 (en) 2001-10-29
NZ334437A (en) 2000-09-29
CN1122031C (zh) 2003-09-24
ES2163195T3 (es) 2002-01-16
KR20000036103A (ko) 2000-06-26
CA2264513A1 (en) 1998-03-19
PL332253A1 (en) 1999-08-30
HK1018443A1 (en) 1999-12-24
CZ87499A3 (cs) 1999-08-11
TR199901205T2 (xx) 1999-07-21
EP0931079B1 (en) 2001-11-21
DE69709774D1 (de) 2002-02-21
EP0931079A1 (en) 1999-07-28
ATE209201T1 (de) 2001-12-15
AU4337797A (en) 1998-04-02
JP2001500508A (ja) 2001-01-16
HUP9904056A2 (hu) 2000-04-28
WO1998011099A1 (en) 1998-03-19
DE69709774T2 (de) 2002-08-08
NO991229L (no) 1999-05-12
IL128929A0 (en) 2000-02-17
NO991229D0 (no) 1999-03-12
CA2264513C (en) 2004-03-30
SK33599A3 (en) 2000-03-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A,7A E 8A ANUIDADES.